LOCUS       NM_001105892            1424 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ripply transcriptional repressor 3 (Ripply3),
            mRNA.
ACCESSION   NM_001105892 XM_001055140 XM_213661
VERSION     NM_001105892.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Osipovich,A.B., Long,Q., Manduchi,E., Gangula,R., Hipkens,S.B.,
            Schneider,J., Okubo,T., Stoeckert,C.J. Jr., Takada,S. and
            Magnuson,M.A.
  TITLE     Insm1 promotes endocrine cell differentiation by modulating the
            expression of a network of genes that includes Neurog3 and Ripply3
  JOURNAL   Development 141 (15), 2939-2949 (2014)
   PUBMED   25053427
REFERENCE   2  (bases 1 to 1424)
  AUTHORS   Okubo,T., Kawamura,A., Takahashi,J., Yagi,H., Morishima,M.,
            Matsuoka,R. and Takada,S.
  TITLE     Ripply3, a Tbx1 repressor, is required for development of the
            pharyngeal apparatus and its derivatives in mice
  JOURNAL   Development 138 (2), 339-348 (2011)
   PUBMED   21177346
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474083.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001055140.1, XM_213661.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK844273.1, CB556533.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132296, SAMD00132304
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..1424
                     /gene="Ripply3"
                     /gene_synonym="Dscr6"
                     /note="ripply transcriptional repressor 3"
                     /db_xref="GeneID:288239"
                     /db_xref="RGD:1308788"
     exon            1..179
                     /gene="Ripply3"
                     /gene_synonym="Dscr6"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..528
                     /gene="Ripply3"
                     /gene_synonym="Dscr6"
                     /note="Down syndrome critical region homolog 6; Down
                     syndrome critical region gene 6; ripply3 homolog"
                     /codon_start=1
                     /product="protein ripply3"
                     /protein_id="NP_001099362.1"
                     /db_xref="GeneID:288239"
                     /db_xref="RGD:1308788"
                     /translation="MRPEAAAAREAQGRISHCPGDDPGRPPLPRGPESSIPAPWRPWM
                     SPPRDADLTRTERPPWEDQQTLGSKGAFGFQHPVRLYLPISKRQEYLQSSGEKVLASF
                     PVQATIHFYNDDSESSSEEEQEEEAQPNHLQCLEAEVRDSALEERAE"
     exon            180..252
                     /gene="Ripply3"
                     /gene_synonym="Dscr6"
                     /inference="alignment:Splign:2.1.0"
     exon            253..314
                     /gene="Ripply3"
                     /gene_synonym="Dscr6"
                     /inference="alignment:Splign:2.1.0"
     exon            315..1424
                     /gene="Ripply3"
                     /gene_synonym="Dscr6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgagccggt aggtgagcgc gctgggccag gggggaccag gcgccgtcgg gctgcgggac
       61 tcgcgcgacg cccgcaccat gagacccgag gcggccgcag cccgggaggc gcagggacgc
      121 atctcccact gtccggggga tgatcccggg aggccaccgc tgccacgcgg gccagaaagt
      181 tccattccag ccccgtggag accgtggatg tcgcctccca gagatgctga tctgaccaga
      241 actgaacgtc cgccttggga ggaccaacaa accttggggt caaagggagc ctttggattc
      301 cagcatcctg tcagacttta cttgcccatt tcaaagcgtc aagaatacct gcagagttct
      361 ggggaaaaag tgctggccag cttcccagtg caagccacca ttcatttcta caacgatgac
      421 tctgagtcta gctctgagga ggagcaggag gaggaggctc agcccaacca ccttcagtgc
      481 ctggaggcag aagtcaggga ttccgctctg gaggaaaggg cagagtaagt ggcaaacctg
      541 tgagacaaag gagtggcctc tggaagggta gctgcctgca aactgagaga gcctctctcc
      601 tatgctggtc actgtgtccc agggacagcc tagcctgcca ggattcttct ccagcctcct
      661 ctgtggcaag ttcagaggct ggactgtgct cagtacctgc tcaggccacg aactcaactt
      721 ctattttctt gatgtatgta tgtgtgtgtg tgtgtgtctg tgtctgtgta tctgtctgtg
      781 tgtgtgcaca catgtgctca tgcatacttt tgaggaaggg tgcctgatga ggtgctctca
      841 ggaagaaggc ctttggagct cactgccact ctgaatgtta ctcatccgta agtctcacca
      901 cccctctctt gcccagagac ccattatcta gtgattcttc ccttcataaa aataatttaa
      961 atattaattc aaatgttaag agttcatttg gttattcatt ttaagagttt catttgaatg
     1021 aaagtagctg tttggaaaaa tatcctttta cttgccaaaa aaaaaaaaaa aaaaaaccaa
     1081 aattaaaaca ctgaataatt ttcacaggaa taagaagtaa gaagttaaga tctctttagg
     1141 ggataaaaca gctgtttctg agaactgtat aagagctgtg tgtttaagta tatatgttat
     1201 aaggggttaa tttttattac ttggtgacca gcatggtctt gttatttgca tgaaatggca
     1261 ctatttttaa ttaaagtttc ttatgtgaaa attgctttga gttttatcat tttgacaatc
     1321 caaggactct gccatcaagg ctctccctaa ttatcttacc agaatctgtc ttcctgtata
     1381 ttccaccctg tatggatttt tacttggaat aaatattttg aaag
//
