LOCUS       NM_001100660            4162 bp    mRNA    linear   ROD 12-DEC-2024
DEFINITION  Rattus norvegicus RHO family interacting cell polarization
            regulator 1 (Ripor1), mRNA.
ACCESSION   NM_001100660 XM_001075785 XM_214666
VERSION     NM_001100660.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4162)
  AUTHORS   Mardakheh,F.K., Self,A. and Marshall,C.J.
  TITLE     RHO binding to FAM65A regulates Golgi reorientation during cell
            migration
  JOURNAL   J Cell Sci 129 (24), 4466-4479 (2016)
   PUBMED   27807006
REFERENCE   2  (bases 1 to 4162)
  AUTHORS   Gao,K., Tang,W., Li,Y., Zhang,P., Wang,D., Yu,L., Wang,C. and Wu,D.
  TITLE     Front-signal-dependent accumulation of the RHOA inhibitor FAM65B at
            leading edges polarizes neutrophils
  JOURNAL   J Cell Sci 128 (5), 992-1000 (2015)
   PUBMED   25588844
REFERENCE   3  (bases 1 to 4162)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   4  (bases 1 to 4162)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 4162)
  AUTHORS   Patrakka,J., Xiao,Z., Nukui,M., Takemoto,M., He,L., Oddsson,A.,
            Perisic,L., Kaukinen,A., Szigyarto,C.A., Uhlen,M., Jalanko,H.,
            Betsholtz,C. and Tryggvason,K.
  TITLE     Expression and subcellular distribution of novel
            glomerulus-associated proteins dendrin, ehd3, sh2d4a, plekhh2, and
            2310066E14Rik
  JOURNAL   J Am Soc Nephrol 18 (3), 689-697 (2007)
   PUBMED   17251388
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FQ147070.1, BF524907.1 and AY724537.1.
            
            On or before Aug 29, 2012 this sequence version replaced
            XM_001075785.3, XM_214666.6.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132264 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-443               FQ147070.1         1-443
            444-771             BF524907.1         52-379              c
            772-4162            AY724537.1         1-3391
FEATURES             Location/Qualifiers
     source          1..4162
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..4162
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /note="RHO family interacting cell polarization regulator
                     1"
                     /db_xref="GeneID:291974"
                     /db_xref="RGD:1307772"
     exon            1..104
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            105..231
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..3781
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /note="protein FAM65A; family with sequence similarity 65,
                     member A"
                     /codon_start=1
                     /product="rho family-interacting cell polarization
                     regulator 1"
                     /protein_id="NP_001094130.1"
                     /db_xref="GeneID:291974"
                     /db_xref="RGD:1307772"
                     /translation="MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRNFTVFSPPG
                     PQRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYAALKRGLTAYLEVHQQEQEKLQRQ
                     IKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMV
                     RAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARL
                     CVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLAN
                     HVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKA
                     STVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSG
                     TARYSSTPKPLVQQPEPLPVQVTFRRPESLSSGSMDEEPPLTPALVNGHAPYSRTLSH
                     ISEASVDAALTEAMEAVDLKCPAPGPSPLVYPESTHVEHVSSVPPVADNGRSATSPAL
                     STAGPAPTFIDPASSTQLDLVHKATDSGSSELPSITHTMASSTYSAVSPINSVPGLTS
                     TTVGSTHKPMPSPLTSTGSIPSVTDSIQTTTSPTHTTPSPTHTTVSPTHSTPSPTHTT
                     VSPSNAALSPSNATPSLSHSTTSPTQKATMSTHTTSAVGPVQTTTSPISTTVSPSPSV
                     DTAIISSSSAVPSVPGPEARPCSHPTSTPYTKADPTAACTSSPSLASSGPKPLTSPAP
                     DSLEQILKSPSSSPSSIVPEPQRSELSLALVAQAPVPEATGGAGDRRLEEALRTLMAA
                     LDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDED
                     EDNDSPGDRPTSSPEVVAEERLDSSNAQCLSTGCSALDATLVQHLYHCSCLLLKLGTF
                     GPLRCQEAWALERLLREARVLQEVCEHSKLWGNAVTSAQEVVQFSASRPGFLTFWDQC
                     TEGLNPFLCPVEQVLLTFCSQYGARLSLRQPGLAEAVCVKFLEDALGQKLPRRPHSGP
                     GEQLTIFQFWSYVEVLDSPSMEAYVTETAEEVLLVQNLNSDDQAVVLKALRLAPEGRL
                     RKDGLRALSSLLVHGNSKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDEDVQTRVA
                     GCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRQLEESLDALP
                     CLFGPSSMASTAF"
     exon            232..384
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            385..463
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            464..487
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            488..541
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            542..694
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            695..758
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            759..802
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            803..928
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1077
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1207
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            1208..2599
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            2600..2721
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            2722..2854
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            2855..2990
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            2991..3152
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            3153..3311
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            3312..3508
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            3509..3592
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            3593..3683
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
     exon            3684..4130
                     /gene="Ripor1"
                     /gene_synonym="Fam65a; RGD1307772"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggctggcg ccggccgcgg cgacagcggc agctgcagcg cgagcaggcc cggcaacgcc
       61 gagagtaccg acagcgcgag gtccttgcag cccagcgcag ccatggagcc ccgcgcgaac
      121 tcattccatg atgtccctgt cggtgcggcc gcagcgccgc ctgctcagcg cccgggtcag
      181 taggagccag tccttcgcag gcgtcctcgg cagccaagag cgcgggccca ggaacttcac
      241 ggtcttcagc ccaccagggc ctcaacggaa gcctttagtg ctctcccgag tgtcaaggat
      301 gttttctgtg gcccacccag cccccaaggt gccacagcct gagaggctgg acctggtata
      361 tgctgctctt aagcggggac tgacggccta cttggaagtg catcagcaag agcaggagaa
      421 gctccagcgc cagataaagg agtccaagag gaattcccgc ctaggattcc tgtatgactt
      481 ggataagcaa gtcaagtcca ttgaacgttt tcttcgacga ctggaattcc atgccagtaa
      541 gattgatgag ctgtatgaag catactgtgt ccagcggcgt ctcagggatg gtgcctacaa
      601 catggttcgt gcttatagca ctgggtcccc agggagtcga gaggcccgag acagcctggc
      661 tgaggccacc cgaggccatc gagagtatac agagagcatg tgtcttctgg agaatgagct
      721 ggaggcacag ctgggcgagt ttcatctccg gatgaaaggg ttggctgggt tcgccaggct
      781 gtgtgtgggc gatcaatatg agatctgcat gaaatacggc cgccagcgct ggaagttacg
      841 aggccgaata gagagtagtg gaaagcaagt gtgggacagt gaagagactg tctttcttcc
      901 tctgctcaca gaattcctgt ctatcaaggt gacagaatta aaaggactgg ctaaccatgt
      961 agtcgtgggc agtgtctcct gtgagaccaa ggacctgttt gccgccctgc cccaggttgt
     1021 ggctgtggat atcaatgatc tcggcactat caagctcagc ctagaagtca tatggagtcc
     1081 ctttgacaag gatgaccagc cttcagctgc ttctacagtc aacaaagctt ccacagtcac
     1141 caagcggttt tccacatata gccagagtcc accagataca ccctcacttc gggagcaggc
     1201 tttttataac atgttacggc ggcaggagga gttagagaat gggacagcat ggtccctgtc
     1261 atccgaatct tctgatgatt catccagccc gcagctctca ggcactgctc gatactcatc
     1321 aactcccaag cctctggtgc aacagcctga gcccctgcct gtccaagtta ccttccgaag
     1381 gccagagagc ctctcctctg gttccatgga tgaagagcca cctctgaccc cagccctggt
     1441 caatgggcat gccccttaca gtcggactct cagccacatc agtgaagcca gcgtggatgc
     1501 tgccttgact gaggccatgg aagctgtgga cttaaaatgc ccagccccag ggcctagccc
     1561 acttgtatat ccagagtcca cccatgtgga gcatgtcagt agtgttcctc ctgttgcaga
     1621 caatggccgt tctgccacaa gtcctgccct aagtacagct ggccctgccc ccacatttat
     1681 agaccctgcc tcatctacac agctagactt agttcacaaa gccacagact ctggctcttc
     1741 tgagttgcca agcatcacac atactatggc aagctctaca tatagtgctg tgagcccgat
     1801 caacagtgtt ccaggcctaa cttccaccac tgtaggttct acccacaaac ccatgccctc
     1861 tcccctcacc tctacaggct ctatccccag tgtcacagac tcaatccaga ctaccacaag
     1921 cccaactcac accaccccaa gccctaccca cactactgta agccctacac atagcactcc
     1981 aagtcccacc cataccactg taagtcccag caatgctgct ctaagcccca gcaatgctac
     2041 tccaagcctc agccacagta ccactagtcc tactcaaaaa gccacgatgt caactcatac
     2101 cactagtgct gtgggcccag tccagaccac tacaagtccc atttctacaa ctgtaagccc
     2161 ctccccttct gtagacactg ctataatctc cagttcctct gcagtaccct ctgtcccagg
     2221 ccctgaagca cggccttgta gtcacccaac ctctactccc tacactaaag cagaccccac
     2281 agcagcctgc acctcttctc cgagtcttgc ttcctctggt ccaaaacccc tcacaagccc
     2341 tgccccagac tcgctagaac aaatccttaa gagcccaagt tcctctccgt catccatagt
     2401 ccctgaaccc caacgttcag aacttagcct ggccttggtt gctcaagccc cagtccctga
     2461 agccactgga ggagctgggg acagaaggct cgaagaggct ctcaggaccc taatggctgc
     2521 cctggatgat tatcgaggtc agttccctga gctccagggc ctggagcagg aggtgactcg
     2581 gctggagagt ctgctcatgc agaggcaagg cctgactcga agccgggcct ccagtcttag
     2641 catcaccgtg gagcatgccc tggagagctt cagcttcctc aatgatgatg aagatgaaga
     2701 caatgacagt cctggggaca ggcccacaag cagcccagag gttgtggctg aggaaagact
     2761 agactcatca aatgcccagt gtctaagcac agggtgttca gccctggatg ctaccttggt
     2821 ccagcacctg taccactgca gctgcctcct gctgaaactg ggcacatttg ggcccctgcg
     2881 ctgccaggag gcatgggccc tggaacggct gctgagggaa gctcgagtgc tccaggaagt
     2941 gtgtgagcac agcaagctgt ggggaaatgc tgtcacatct gcccaggaag tggtacagtt
     3001 ctctgcctct cggcccggtt tcctgacctt ttgggaccag tgtacagagg gactcaaccc
     3061 cttcctctgc cctgtggagc aggtgctcct cactttctgc agccagtatg gtgcccgtct
     3121 ttccctgcgc cagccaggct tagccgaggc tgtgtgtgtg aagttcctgg aagatgctct
     3181 ggggcagaag ctgcccagga ggccccactc aggccccggg gagcagctca ccatcttcca
     3241 attctggagt tatgtagaag tcttggacag cccctccatg gaagcctatg tgacagagac
     3301 cgcagaggag gtgttactgg tacagaacct gaactccgat gaccaggcag ttgtgctgaa
     3361 ggctctaagg ttagccccag aggggcgcct gaggaaggat gggcttcggg ctcttagctc
     3421 cctgctggtc cacggcaata gcaaagtcat ggctgctgtc agcacccagc ttcggagcct
     3481 gtcacttggt cctgtcttcc gggaaagggc tcttctgtgc ttcctggacc agcttgagga
     3541 tgaggatgtg cagactcgag tggccgggtg cctggctttg ggctgtatca aggctcctga
     3601 gggcattgag cccctggtgt acttgtgtca aacagacaca gaagctgtga gggaagctgc
     3661 ccggcagagc ctccagcagt gtggggaaga aggacagtct gctcatcgcc agctagagga
     3721 gtccctggat gccctgccct gcctctttgg gcccagcagc atggccagca cagcattctg
     3781 aactctgatt gccagctccc agtgctcctt ccctcatttt cagggctcac taggcactgg
     3841 cagggagggt gagggctggt tccagtcacc tctccccaca aattcctatc aatgaaaatc
     3901 taatatattc ttctgttatc actggggttg gtagaatgcc tgaaatgaag tgcctcccag
     3961 ccggttctgc atagccacaa acagtgtcag gggcctgacc gtttggtcag cttgctctgc
     4021 ctcaccacat cccttggttt tgtattttat ttacagagtt ttacagataa taaaaaagca
     4081 aaatgtgttt cctacgtggc ttggtgcacg cccgagcctc tgctccaaca aaaaaaaaaa
     4141 aaaaaaaaaa aaaaaaaaaa aa
//
