LOCUS       NM_001399263            3123 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus RAD50 interactor 1 (Rint1), transcript variant 1,
            mRNA.
ACCESSION   NM_001399263 XM_039108552
VERSION     NM_001399263.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3123)
  AUTHORS   Civril,F., Wehenkel,A., Giorgi,F.M., Santaguida,S., Di Fonzo,A.,
            Grigorean,G., Ciccarelli,F.D. and Musacchio,A.
  TITLE     Structural analysis of the RZZ complex reveals common ancestry with
            multisubunit vesicle tethering machinery
  JOURNAL   Structure 18 (5), 616-626 (2010)
   PUBMED   20462495
REFERENCE   2  (bases 1 to 3123)
  AUTHORS   Arasaki,K., Taniguchi,M., Tani,K. and Tagaya,M.
  TITLE     RINT-1 regulates the localization and entry of ZW10 to the syntaxin
            18 complex
  JOURNAL   Mol Biol Cell 17 (6), 2780-2788 (2006)
   PUBMED   16571679
REFERENCE   3  (bases 1 to 3123)
  AUTHORS   Hirose,H., Arasaki,K., Dohmae,N., Takio,K., Hatsuzawa,K.,
            Nagahama,M., Tani,K., Yamamoto,A., Tohyama,M. and Tagaya,M.
  TITLE     Implication of ZW10 in membrane trafficking between the endoplasmic
            reticulum and Golgi
  JOURNAL   EMBO J 23 (6), 1267-1278 (2004)
   PUBMED   15029241
REFERENCE   4  (bases 1 to 3123)
  AUTHORS   Xiao,J., Liu,C.C., Chen,P.L. and Lee,W.H.
  TITLE     RINT-1, a novel Rad50-interacting protein, participates in
            radiation-induced G(2)/M checkpoint control
  JOURNAL   J Biol Chem 276 (9), 6105-6111 (2001)
   PUBMED   11096100
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jan 5, 2022 this sequence version replaced XM_039108552.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.14794.1,
                                           SRR26360186.2587974.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-164               JAXUCZ010000004.1  12247954-12248117   c
            165-210             JAXUCZ010000004.1  12247505-12247550   c
            211-395             JAXUCZ010000004.1  12241499-12241683   c
            396-637             JAXUCZ010000004.1  12236780-12237021   c
            638-811             JAXUCZ010000004.1  12232624-12232797   c
            812-961             JAXUCZ010000004.1  12232387-12232536   c
            962-1118            JAXUCZ010000004.1  12231131-12231287   c
            1119-1229           JAXUCZ010000004.1  12228077-12228187   c
            1230-1455           JAXUCZ010000004.1  12227765-12227990   c
            1456-1593           JAXUCZ010000004.1  12227188-12227325   c
            1594-1793           JAXUCZ010000004.1  12224853-12225052   c
            1794-2008           JAXUCZ010000004.1  12216628-12216842   c
            2009-2189           JAXUCZ010000004.1  12215807-12215987   c
            2190-2308           JAXUCZ010000004.1  12215615-12215733   c
            2309-3123           JAXUCZ010000004.1  12213156-12213970   c
FEATURES             Location/Qualifiers
     source          1..3123
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q11"
     gene            1..3123
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /note="RAD50 interactor 1"
                     /db_xref="GeneID:296750"
                     /db_xref="RGD:1560433"
     exon            1..164
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     CDS             123..2501
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /note="isoform 1 is encoded by transcript variant 1;
                     RAD50-interacting protein 1"
                     /codon_start=1
                     /product="RAD50-interacting protein 1 isoform 1"
                     /protein_id="NP_001386192.1"
                     /db_xref="GeneID:296750"
                     /db_xref="RGD:1560433"
                     /translation="MLAAGEIGDVPAALCCPESGDETKNTEEKSDVNTAALVGSEQLG
                     QGGGDHELLLYVSAFIEKEVGSDLKSLKTLGKLIEQMTESKVKLEEQVLTISSEIPKR
                     IQSALKDAEEAKQALGDILGQEAPLFSSINSHLLIAQPWTDDLGAMISQIEEIERHLT
                     YLKWVSQIEELSDNIQQYLMTNSVPEAASTLVTMTELDIKLQESSCTHLLSFMRATVK
                     FWYKILKDKLTSDFEEILAQLHWPFITHTQSQAVGASRPASTPETYASLETLFCQLLK
                     LQASDELLTESKQLPEKYCLPASPSVALPIQIMLVPLQKRFRYHFRGSRQTNVISKPE
                     WYFAQVLLWIGSHSHFLDEKIQPILDKVGSAVNARLEFSRGLVMLILEKLASDIPCLL
                     YDDSLFCHLVDEVLLFERELHSVHGYPSTFASCMHILSEETCFQRWLTVERKFALQKM
                     DSMLSSEAAWVSQYKDITDVDEMKVPDCAEVFMTLLLVITDRYKNLPTASRKLQFLEL
                     QKDLVDDFRIRLTQVMKEETRAPLGFRYCAILNAVNYISTVLADWADNVFFLQLQQAA
                     LEVFAENNVLSKLQLGQLASMESSVFDDMINLLERLKLDMLTRQVDHVFREVKDAAKL
                     YKKERWLSLLSQSEQAVMSLSSSACPLLLTLRDRLLQLEQQLCFSLFNIFWQMLVEKL
                     DLYLYQEIILANHFNEGGAAQLQFDMTRNLFPLFSHYCKRPENYFKHVKEACIVLNLN
                     IGSALLLKDVLQSASEHIPATAALNEVGVYKLAQQDVEILLNLRTNWPNPGK"
     exon            165..210
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            211..395
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            396..637
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            638..811
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            812..961
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1118
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1229
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1455
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            1456..1593
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            1594..1793
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            1794..2008
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            2009..2189
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            2190..2308
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..3123
                     /gene="Rint1"
                     /gene_synonym="RGD1560433"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggtggcgc tcaacccggc gtccctgaag gctggtctgg tcgcctagtg tgtgtgttct
       61 ctagccggac tctgcaggcc aggctggcgg tgcatggaat ccaggactcg agcggaggca
      121 ggatgcttgc agctggcgag atcggcgatg tgccggcagc cctgtgctgc cccgagagcg
      181 gtgacgaaac gaagaacaca gaggagaaaa gtgacgtgaa caccgcagct cttgttggaa
      241 gtgagcagct cggccaaggt ggcggtgacc atgagcttct tttgtatgtg tctgcgttca
      301 tagagaagga ggtgggaagt gaccttaagt ctttgaagac acttggcaaa ctcatagaac
      361 aaatgacaga gagcaaagtg aagttagaag agcaggtact tacgatttca tcagaaatcc
      421 ctaaaagaat tcaaagtgct ttaaaagatg cagaggaggc caaacaagcc cttggtgaca
      481 ttctagggca ggaggcacct ctcttcagct ccatcaacag ccatttactg attgcccagc
      541 cctggacgga tgacctaggg gccatgatca gccagataga agagattgag cgacatctca
      601 cttaccttaa gtgggtgtca cagatcgagg agctgagtga taacattcag cagtacctga
      661 tgaccaatag tgtgccagag gcagcctcta ccctggtgac catgacagaa ctggacatca
      721 agcttcagga gtcatcctgt actcatcttc ttagtttcat gagagccaca gttaaattct
      781 ggtataaaat tctcaaggac aagcttacca gtgatttcga ggagatttta gcacagcttc
      841 attggccatt cattacacac acccagtctc aagctgttgg tgcgagccga cctgccagta
      901 cccctgagac gtacgctagc ctggagacac tgttttgtca gctcttgaaa ctacaggcct
      961 cagatgaatt attgactgag tcaaaacaac tcccagaaaa atactgtctt cctgcctctc
     1021 cttctgtggc cctgcccatc cagatcatgc tggttcccct tcagaagaga ttcaggtacc
     1081 acttcagagg cagccggcag accaacgtca tcagcaagcc tgaatggtac ttcgctcagg
     1141 tacttctgtg gattggaagc cattctcact ttctggatga gaagatccag ccaatactgg
     1201 ataaagtggg ttctgcagtg aacgcaaggc ttgagttttc tcgcggcctc gtgatgctca
     1261 tccttgagaa gctggcgtct gatatccctt gcctgctcta tgacgatagt ctcttctgtc
     1321 atctggtaga cgaggtgctg ttgtttgaaa gggagctgca cagtgtccat ggctatccta
     1381 gcacatttgc cagctgcatg cacattctgt cggaggaaac ctgtttccag agatggctga
     1441 ctgtggagag aaagtttgct cttcaaaaaa tggactcaat gctttcatca gaagctgcct
     1501 gggtatccca gtataaagac atcaccgatg tggatgaaat gaaggtccca gactgtgcgg
     1561 aagtctttat gaccctgctt ctggttataa ctgacaggta taaaaatctc cccacagcct
     1621 cccggaagct gcagttcctg gagttacaga aggacctagt ggatgatttt aggatccggt
     1681 tgacacaggt gatgaaggag gagactagag cgcccctggg ctttcggtac tgtgcgattc
     1741 tcaacgccgt gaactatatc tcaacagtgc tggctgactg ggctgacaac gtgttctttc
     1801 tgcagctgca gcaggcagca ctggaggtct ttgcagagaa caacgtcctc agcaaactgc
     1861 agctggggca gctggcctcc atggagagct ccgtcttcga cgacatgatc aacctcttag
     1921 agcgcctaaa gcttgatatg ctgactcgcc aagtagacca tgttttcaga gaagtgaaag
     1981 acgcggctaa gttgtataag aaagaaagat ggctgtccct gctgtctcag tctgaacagg
     2041 cagtgatgtc cctgtccagc tctgcctgcc cactcttgct gaccttacgg gaccggctgc
     2101 ttcagctgga gcagcagctg tgtttctcct tattcaacat cttctggcag atgctcgtag
     2161 agaaactgga cttgtatctg tatcaggaaa taatccttgc taatcacttc aatgagggag
     2221 gagcagccca gctgcagttc gatatgacga ggaacctctt ccctttgttc tctcactatt
     2281 gcaagaggcc agaaaactac tttaaacatg taaaagaagc ctgcatcgtt ctgaatttga
     2341 acatcggttc cgcgttactc ctgaaagacg tccttcagtc agcttccgag cacattcccg
     2401 ccacagcagc cttaaatgaa gttggagttt acaaactggc tcaacaagat gttgagattc
     2461 tgcttaatct gaggacaaac tggcctaacc ctggaaaatg atgcatcttt gagaaaaggg
     2521 tcatttaaca gagcggcagt tggattgaag ttgtctgata aagttctgaa ttgatgaaac
     2581 tggacaaagg aaacttggca gaatcttctc ttgtcttgag ttatgatatc actaaaacaa
     2641 tggccatcct ccaccctccc gttcctaaga acaaaaggaa ggaaaacagc tgtgagacgc
     2701 agagtaattg tgtgcaagta ggaatgcaga catctgaaga cagaatgaga gcaaaggtca
     2761 gccatacctg acccctgacc tccactgtcc taatcaaggg ggccgttgtc aaaggctgga
     2821 ttgtacaatg cttacgggtg caagtaggta gtggagggtc ctttttccag tttgggaatt
     2881 cagtgttcat ataagaaata cactttgagc tgcaagtggt gggagacacc tgtaatccca
     2941 gcattctgaa ggctgaagca gggggatcac tgtgggttcc tgggcaacat agtaagatcc
     3001 tatccatatc aacagaaaaa accaaaccaa accaaaccaa accaaacccc aagaccaaca
     3061 acacagtagt cttatgagat ggtggtgaag ctaccatggt tcttaatatt ctattcttat
     3121 gtc
//
