LOCUS       NM_001107786            4659 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Ras and Rab interactor 2 (Rin2), mRNA.
ACCESSION   NM_001107786 XM_001054910 XM_230647
VERSION     NM_001107786.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4659)
  AUTHORS   Sandri,C., Caccavari,F., Valdembri,D., Camillo,C., Veltel,S.,
            Santambrogio,M., Lanzetti,L., Bussolino,F., Ivaska,J. and Serini,G.
  TITLE     The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and
            morphogenesis via active integrin endocytosis and Rac signaling
  JOURNAL   Cell Res 22 (10), 1479-1501 (2012)
   PUBMED   22825554
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474026.2.
            
            [WARNING] On Oct 18, 2024 this sequence was replaced by
            NM_001107786.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001054910.1, XM_230647.4.
FEATURES             Location/Qualifiers
     source          1..4659
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q41"
     gene            1..4659
                     /gene="Rin2"
                     /note="Ras and Rab interactor 2"
                     /db_xref="GeneID:311494"
                     /db_xref="RGD:1305873"
     exon            1..111
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            112..231
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            232..324
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     CDS             268..2976
                     /gene="Rin2"
                     /codon_start=1
                     /product="ras and Rab interactor 2"
                     /protein_id="NP_001101256.1"
                     /db_xref="GeneID:311494"
                     /db_xref="RGD:1305873"
                     /translation="MSAWTMGARGLDKRGSFFKLIDTIASEIGELKREMVQTDVSLEN
                     GLEPSETYSMVRHKDGGYPEDKDGKTCPRDSGYDSLSNRLSILDRLLHTHPIWLQLSL
                     SEEEAAEVLQAQPPGIFLVRKSSKMQKKVLSLRLPCEFGAPLKEFTIKESTYTFSLEG
                     SGISFADLFRLIAFYCISRDVLPFTLKLPYAISTAKTESQLEELAQLGLNFWSSSADN
                     KPPNSPPPHRPLSSAGICPASLRQLCLINGVHSIKTRTPSELECSQTNGALCFINPLF
                     LKVHSQDLSTGPKRPSTRTPNANGTERPRSPPPRPPPPAINSLHTSPGLSRTEPQTSM
                     PETVHHSKHGNVALLGTKPTPIPPPRLKKQASFLEAESSAKTLTACRPGRSPPEPELE
                     LEVEMGTAGHAGGAPPRDAPGDCTRAPPPDSESQPPPCHGARQRLSDMSLSTSSSDSL
                     EFDRSMPLYGYEADTTSSLEDYEGESDQETMAPPIKSKKKRNSSFVLPKLVKSQLRKM
                     SGVFSSFMTPEKRMVRRIAELSRDKCTYFGCLVQDYVSFLKENKECHVSSTDMLQTIR
                     QFMTQVKNYLSQSSELDPPIESLIPEDQIDVVLEKAMHKCILKPLKGHVEAMLKDFHT
                     ADGSWKQLKENLQLVRQRNPQELGVFAPTPDLMELEKIKLKFMTMQKMYSPEKKVMLL
                     LRVCKLIYTVMENNSGRMYGADDFLPVLTYVIAQCDMLELDTEIEYMMELLDPSLLHG
                     EGGYYLTSAYGALSLIKNFQEEQAARLLSSEARDTLRQWHKRRTTNRTIPSVDDFQNY
                     LRVAFQEVNSGCTGKTLLVRPYITTEDVCQLCAEKFKVEDPEEYSLFLFVDETWQQLA
                     EDTYPQKIKAELHSRPQPHIFHFVYKRIKSDPYGVIFQNGDDLTPS"
     exon            325..425
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            426..618
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            619..730
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            731..803
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            804..895
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            896..2053
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            2054..2359
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            2360..2491
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            2492..2655
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
     exon            2656..4659
                     /gene="Rin2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctgggaag gtttaactct ccattgcttt tggccaaagc agactgttag aaccatttac
       61 ttcgtacaca gatagaacaa agatgaaagg gtctgcagtc cactgcagag gatggagacc
      121 tgagacagaa actcctgaac ttccactgga aaagctcaaa tgtgtgagcc ttcagaactc
      181 tgcagaagac aagcccaagc tgaagaggag agagagatgc tggtctgaca ggagtccccg
      241 gcatgcagta gagcctcgct gggggaaatg tcagcttgga ccatgggcgc ccgaggtctg
      301 gacaagcgag gaagtttctt taagctcatt gacacgatcg cctcggagat cggagaactg
      361 aaacgggaga tggtgcagac agatgtcagc ctggaaaatg gcctggaacc ttctgaaacc
      421 tacagcatgg tgagacacaa ggatggtggc tatcctgaag acaaggacgg gaagacatgt
      481 ccccgagact ctggctatga cagcctctcc aacaggctca gcattctgga caggctcctg
      541 catacccatc ccatatggct gcagctcagt ctgagtgagg aggaggcagc agaggtcctg
      601 caggcccagc ctccagggat ctttttggtt cgtaaatcct ccaaaatgca gaagaaagtc
      661 ctctcccttc gcctgccctg tgaatttgga gcacctctca aagagtttac tataaaggaa
      721 agcacgtaca ccttttccct ggaaggctcg ggaatcagct ttgcagattt attccggctc
      781 attgctttct actgcatcag cagggatgtt ctgccattca ccttgaagct gccttatgcc
      841 atttcaacag ccaagacgga gtctcaactt gaagaactag cccagctggg actaaatttt
      901 tggagctcct cggcagacaa caaaccccca aactccccac ctccccatag gcctctttcc
      961 tcagccggca tctgccctgc ctccttgcgt cagctctgcc ttataaatgg agtgcattct
     1021 ataaaaacca ggacgccttc agagttggag tgcagccaga ccaacggagc cttgtgtttt
     1081 attaatcctc ttttcttgaa agtgcacagc caggacctca gcacaggccc aaagcggccg
     1141 agcacaagga ctcccaacgc gaatggcacc gagagacctc ggtccccgcc acccaggccc
     1201 ccgccacccg ctattaatag tctgcacaca agccctgggc tatccaggac tgaaccccag
     1261 acgagcatgc cagaaacagt ccaccatagc aaacatggga acgtagctct gcttggaaca
     1321 aaaccaactc ccatccctcc accccggctg aagaagcagg cttctttttt ggaagcggaa
     1381 agcagcgcca agaccttgac cgcctgccgg cccggccgga gcccgccgga gcctgagctg
     1441 gagctggagg tggagatggg cacagctggg cacgcaggtg gagccccgcc tagggacgcc
     1501 cccggggatt gcacaagggc gccgccgccc gactctgaat cacagccacc accgtgccat
     1561 ggagccaggc agaggctgag cgacatgagc ctttccactt cctcctcgga ctcgctggag
     1621 ttcgaccgga gcatgcccct gtatgggtac gaggccgaca ccaccagcag cctggaggac
     1681 tacgaagggg agagtgacca ggagacgatg gcacctccca tcaagtccaa aaagaagagg
     1741 aacagttctt ttgtgctgcc caaactggtc aagtcccagt tgcgaaagat gagcggggtg
     1801 ttcagctcct tcatgacccc tgagaagcgc atggtccgca ggatcgccga gctgtcccgg
     1861 gacaaatgca cctatttcgg gtgtctggtg caggactacg tgagcttcct gaaggagaac
     1921 aaggaatgcc atgtgtccag caccgatatg ctgcagacta tccggcagtt tatgacccag
     1981 gtcaagaact atttgtctca gagctctgaa ctggaccccc ctatcgagtc actgatccca
     2041 gaagaccaaa ttgatgtggt gttggagaag gccatgcaca aatgcatctt gaagcccctc
     2101 aagggccacg tggaggccat gctgaaggac ttccacacgg ctgatggctc gtggaaacaa
     2161 ctcaaggaaa acctacagct tgtgcggcag agaaacccgc aggagctggg ggtctttgct
     2221 ccaacccctg acttgatgga gctggagaag atcaagctga aattcatgac catgcagaag
     2281 atgtattcgc cagaaaagaa agtcatgctt ttgctacggg tctgtaagct catctacact
     2341 gtcatggaga acaactcagg gaggatgtac ggggcggacg acttcttgcc ggtcctgacc
     2401 tatgtcatag ctcagtgtga tatgcttgaa ttggacactg aaatcgagta catgatggag
     2461 ctcctagacc catcactgct gcatggagaa ggaggctatt acttgaccag tgcctatggg
     2521 gctctatctc tgataaagaa cttccaagaa gaacaggctg caagactgct cagctcagaa
     2581 gccagggaca ctctgaggca gtggcacaag cggagaacca ccaaccggac tatcccctcc
     2641 gtggatgact ttcagaatta cctccgagtt gccttccaag aggtcaacag tggatgcact
     2701 gggaagactc tccttgtgag accgtacatc accacagagg atgtgtgtca gctctgtgct
     2761 gagaaattta aggtggagga ccctgaagag tacagtctgt ttctctttgt tgatgagaca
     2821 tggcagcaat tggcagagga cacttatcct cagaagatca aggctgagct gcacagccgg
     2881 cctcagcccc acatcttcca ctttgtgtac aagcgaatca agagtgatcc ttatggtgtg
     2941 attttccaga atggagatga tctcactccc tcatagggga cacatgggac ttcctattga
     3001 tatatccaaa agggagctga gagtctagct ttctggctgc cgcctgtttg agcttagaag
     3061 acagccacct cctcaaggat ccctcagttc agtgactaag ccatccgtag gctgacttgg
     3121 ctaagggcat cctttagata cattgcccag atgaggtagc tgtgatttgg aaaatagtaa
     3181 gactctcctc cagaaatggt gaattgcatt taatggttca gatgtcctga gttcactggc
     3241 tagttaacta gttaacctta gccagcttcg aggttggctt acacatgtgt atgtgtgctg
     3301 aggaaacact taaggtacaa attcttctct tggattcgat attaagtgtt gacaagactg
     3361 tccgatgcag tgcgtccgat acctctcagc tctgtggatg gctccctcct tccctctttc
     3421 ccttctttcc tccatccttc atcctatact tttttttttt tacaaagagc ctttgtgttt
     3481 ttatatattt catagaaaaa tttatagcag ttgcaggtaa actgtcagga ttggttttta
     3541 aaatattttt gtaactttaa aaatattcta taagtatgca tgtgatttaa catttaatat
     3601 ttgaagatga atctcttgct ggatttgaga gtactgcatt ttagacgcct cttagatgtc
     3661 tctcttttgt aactggatgt ttctgcaaat ttgtggggag agacttctga ttgtcttaga
     3721 gcaatccctg actggccaca ggcggccttt gaaaaaataa accgggtgta ctgttacatt
     3781 gttctctttt agtgctagtg taccttttgt tgtgtttgtt ttttaagcaa tcaatgttga
     3841 gaattaggag agaaacgaat gtagagagag gtagagagag aaacacagac tctaaggagg
     3901 ggctgaggaa cgtagtctgc aggttcaggc tctttggagg acatagagaa aaggagtcag
     3961 tactgtaaga tatgtgctac agtgagtttt gacaaagacc tgttccatat gctatgtgct
     4021 ctgggaaaca attttaaaaa ccccgtaagg aaaagcaaat caaggataac gatccctatg
     4081 gccgtttgta agccaccact aaggacatcc gtttatttgg aggcagaaac caagtaatgt
     4141 aggatatggg ttttgttgag ttcgatgaga tgatgagaag agaatgcacc aaaaccaaaa
     4201 ccaaaccaaa agaaaggaaa ccctgttcat tataggactg gacagtggtg ggggcgtggc
     4261 tcagtggtag agctggcata cacagaccaa catgctgggt tccaccctca gcatggcaaa
     4321 tatgagcaaa gccagcataa aacatgtctg tatggtgaag ttagatttat gttatataaa
     4381 atgaatttac gggcacgcat attctagaag ggtcatatat tagtgtaata caggtcatgg
     4441 caaaacaaaa acaaaaaaaa tgttactgtc ttgtgtaagg atgcataggc atctgatttg
     4501 ggggaccttg taccttgtac ccctggcttt tgttgtaccc aaacccttgg cacatgctgt
     4561 gttgtgcttc cttttgtaaa tgattttcaa tggaattttg cacataatac attgtaatac
     4621 tgtacaataa tcctgtgtaa aacaattttt ttcaatatt
//
