LOCUS       XM_006231255            6865 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus RIC1 homolog, RAB6A GEF complex
            partner 1 (Ric1), transcript variant X1, mRNA.
ACCESSION   XM_006231255
VERSION     XM_006231255.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006231255.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006231255.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6865
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6865
                     /gene="Ric1"
                     /note="RIC1 homolog, RAB6A GEF complex partner 1; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 19 ESTs, 4 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 77 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:309306"
                     /db_xref="RGD:1310016"
     CDS             37..4320
                     /gene="Ric1"
                     /codon_start=1
                     /product="guanine nucleotide exchange factor subunit RIC1
                     isoform X1"
                     /protein_id="XP_006231317.1"
                     /db_xref="GeneID:309306"
                     /db_xref="RGD:1310016"
                     /translation="MYFLSGWPKRLLCAPRSPAEAPLHVQSDPRRAFFAVLAPARLSI
                     WYSRPSVLIVTYKEPAKSSAQFGSYTQAEWRPNSTMIAVSTANGYILFFHITSSRGDK
                     YLYEPVYPKGSPQMKGIPHFKEEHCAPALNLEMKKILDLQAPIMSLQSVLEDLLVATS
                     DGLLHLIHWEGMTNGRKAINLSTVPFSVDLQSSRVGSFLGFADVHIKDMEYCATLDGF
                     AVVFNDGKVGFITPVSSRFTAEQLHGVWPQDVVDGTCVAVNNKYRLMAFGCASGSVQV
                     YTIDNTTGAMLLSHKLELTAKQYPDIWNKTGAVKLIRWSPDNSAVIVTWEYGGLSLWS
                     VFGAQLICTLGGDFAYRSDGTKKDPLKINSMSWGAEGYHLWVISEFGSQHTQTDTDLG
                     SAVKEPSILLFQFIKSVLTVNPCMSNQEQVLLQGEDRLYLNCGEASQTQNLKYSSARA
                     EHMPRHEKSPFADGGLESPGLSTLLGHRHWHVVQISSTYLESNWPIRFSAIDKLGQNI
                     AVAGKFGFAHYSLLTKKWKLFGNITQEQNMIVTGGLAWWNDFMVLACYNLSDRQEELR
                     IYLRTSNLDNAFAHVTKAPIETLLLSVFRDMVVVFRADCSICLYSIERKSDGSSTTAS
                     VQVLQEVSMSRYIPHPFLVVSVTLTSVSTENGITLKMPQQARDAESIMLNLAGQLIMM
                     QRDRSGPQIREKDSNPSQRKLVSNALPFCPPVVLAQSVENVWTTCRANKQKRHLLEAL
                     WLSCGGAGMKVWLPLFPRDHRKPHSFLSQRIMLPFHINIYPLAVLFEDALVLGAVNDT
                     LLYDSLYTRNSAREQLEVLFPFCVVERTSQIYLHHILRQLLVRNLGEQALLLAQSCAA
                     LAYFPHVLELMLHEVLEEEASSREPIPDPLLPTVAKFISEFPLFLQTVVHCARKTEYA
                     LWNYLFAAVGNPKDLFEECLMAQDLDTAASYLIILQNMEVPAVSRQHATLLFNTALEQ
                     GKWDLCRHMIRFLKAIGSGESETPPSTPTSQEPSSSGGFEFFRNRSISLSQSAENVPP
                     GKFGLQKTLSMPTGPSGKRWSKDSDCAENMYIDMMLWRHARRLLEDVRLKDLGCFAAQ
                     LGFELISWLCKERTRAARVDNFVVALKRLHKDFLWPLPIIPASSISSPFKNGKCRAVG
                     EQLLKSQSADPFLTPEMDAGISTIQRSQSWLSSIGPTHRDADIASSPGPQMQDAFLSP
                     LSNRGDECSIGSATDLTESSSMVDGDWTMVDENFSTLSLTQSELEHISMELASKGPHK
                     SQVQLRYLLHIFMEAGCLDWCVVIGLILKESSVVSQILGIAQSSEIDGEMLQNIKAGL
                     HAVDRWASTDCPGYKPFLNIIKPQLQKLSEITEELVQPDTFQPITVGKSPEQTSPRAE
                     ESRGSSSHGSITQSETGSNNSMVSRKEEDTTQADEEEPFQDGAYDCSVS"
ORIGIN      
        1 ggggccgccg gggactgtcg gggccgcgcg cggaccatgt atttcctgag cggctggccc
       61 aagaggctgc tctgcgcgcc gcggagcccg gccgaggcgc cgctccacgt ccagtctgac
      121 cctcggagag cgttcttcgc cgtgctggcc ccggcccgcc tcagcatctg gtacagccga
      181 cccagtgtgt taattgtaac atacaaggaa ccagctaaat cgtctgctca gtttggatct
      241 tacacacaag ctgaatggag gccgaacagt accatgatag cagtgtcaac agcaaatggc
      301 tacatcttgt tttttcatat tacatcttca agaggggata aataccttta tgaaccagtg
      361 tatcccaaag gaagtccaca aatgaagggg atacctcatt ttaaggaaga acattgcgcc
      421 ccagcattga atttagaaat gaagaaaata ctggatttgc aagcacccat catgagtttg
      481 cagtctgtgc tggaagatct ccttgttgca acttctgatg gacttcttca tcttattcat
      541 tgggaaggaa tgacaaatgg aagaaaagcc atcaatctct ctacagtacc cttttcagta
      601 gaccttcagt catctagagt aggttcattc ctcggctttg cagatgtgca cattaaagat
      661 atggaatatt gtgccacact tgatggattt gctgttgtgt ttaatgatgg taaagttgga
      721 tttattacac cagtatcgag tagatttact gcagagcagc ttcatggagt ttggccacaa
      781 gatgttgttg atgggacttg tgttgcagta aataacaaat accgactgat ggcctttggt
      841 tgtgcaagtg gttctgtgca agtctatacg atagacaaca ctactggagc catgctgctg
      901 tctcataaac tagagcttac agcaaagcag tatcctgaca tctggaacaa aacaggagct
      961 gttaaattga ttagatggtc tcctgacaac agtgctgtaa tagtaacctg ggaatatgga
     1021 ggtctttctc tgtggagtgt gtttggagcc cagctgattt gtacacttgg aggagacttt
     1081 gcttacaggt cagatggtac caaaaaagat ccccttaaga tcaactccat gagctggggt
     1141 gcagaaggct atcacctatg ggtaatcagt gaatttggtt ctcagcacac tcaaactgac
     1201 actgacctcg ggagtgcagt taaagagccc agcattttgt tatttcagtt tatcaagagt
     1261 gtactcactg taaacccttg tatgagtaac caagaacagg tgttacttca gggagaagat
     1321 cgcttatact tgaactgtgg agaagcctca cagacccaaa atctgaagta ctcttcagca
     1381 cgtgctgagc atatgcccag acacgagaag agcccatttg cagatggagg tctagagtct
     1441 ccaggattaa gcactttact tggacatcga cattggcatg ttgtacagat ttccagcacc
     1501 tatctagaaa gcaattggcc tatacggttt tcagctattg ataaacttgg acaaaatatc
     1561 gctgtggctg gcaagtttgg gtttgcgcat tattctttac ttaccaagaa atggaaactt
     1621 tttggaaaca ttactcagga gcaaaatatg attgtgactg gtggcttagc ctggtggaat
     1681 gactttatgg tccttgcctg ttacaactta agtgaccgcc aagaagagct cagaatctac
     1741 ctacgaacat caaacctgga caatgccttt gctcatgtca ccaaagcacc aatagaaaca
     1801 ttactgctta gtgtcttccg ggacatggtg gtagtgttta gagcagactg ttcaatatgc
     1861 ctctacagta ttgaaagaaa atccgatggt tcgagtacga cagcgagtgt tcaggttctt
     1921 caggaggtct ccatgtcgag gtacattcct catcccttcc tggtggtgtc tgtcacactg
     1981 acgtcagtga gtacagagaa tggcatcacc ttgaaaatgc cacaacaggc tcgggatgca
     2041 gagagcataa tgctgaacct tgcaggacag ctcatcatga tgcagaggga ccggtcaggc
     2101 cctcagatcc gggagaagga cagtaaccct agccaaagga aactcgtgag taacgctctg
     2161 ccgttctgcc ctcccgttgt actagctcag tcagtggaaa atgtctggac tacctgtcga
     2221 gcaaacaaac aaaagcgtca ccttctggag gccctctggc tgagctgtgg tggtgcgggg
     2281 atgaaggttt ggctccctct cttccccagg gatcaccgaa agccccactc cttcttgtcc
     2341 cagcggatca tgctgccttt ccacatcaac atttaccccc tcgccgttct gtttgaagac
     2401 gcgttggtcc ttggtgctgt caatgacact ctgctctatg attctctgta cacacggaac
     2461 agtgctaggg agcagctgga ggtgctcttt cccttctgcg ttgtggagag aacctctcag
     2521 atctacctcc accatatcct ccgccagctc ctggtcagga accttggcga gcaagccctc
     2581 cttctggctc agtcgtgcgc tgcgttagct tacttccctc atgtgttgga gctcatgctc
     2641 catgaagtgc tggaagagga agctagctca cgggagccca ttcccgaccc gctgcttcct
     2701 accgtggcga agtttatctc cgagttcccc ctcttccttc agacagtcgt gcactgcgcc
     2761 cggaagactg agtatgcgct gtggaattac ctttttgcag ctgttgggaa ccccaaggac
     2821 ttattcgagg aatgtttgat ggctcaggac ttggacacag ctgcctctta ccttattatc
     2881 ctacagaata tggaagtccc cgcagtaagt aggcagcatg ccacccttct gttcaacaca
     2941 gcactggaac agggcaaatg ggacctgtgt cgacacatga ttagatttct taaagccatt
     3001 ggttctggag aatctgagac ccctccatcc acaccgacat ctcaggagcc cagttcaagt
     3061 ggtggctttg agttcttcag gaatcgcagc atcagtttat cccagtcagc tgaaaatgtt
     3121 cctcctggta aattcggctt acagaaaact ctaagtatgc caactggtcc ttctgggaaa
     3181 aggtggagca aagacagtga ctgtgcagag aacatgtaca tcgacatgat gctgtggcga
     3241 cacgctcggc gtctcctaga agacgtgcgc ctgaaggacc tgggctgctt tgcagcccag
     3301 ctaggctttg aactcatcag ttggctttgc aaagaacgca ctcgagccgc ccgtgtggac
     3361 aactttgtag tagccctgaa gagactgcac aaggatttcc tgtggcctct tcccattatc
     3421 ccagcctctt ccattagttc ccctttcaaa aatgggaaat gtcgagcagt gggagagcag
     3481 ctgttgaagt ctcagtcagc tgaccctttt cttacccctg agatggatgc cggcatctct
     3541 accatccaac gcagtcagag ctggctcagc agcattggtc ccacccatcg tgacgcagac
     3601 atagcctcat ctcctggacc acaaatgcaa gatgctttcc tctcaccatt atctaataga
     3661 ggggatgaat gcagcattgg ctcagctaca gacttgactg aaagcagctc catggtggat
     3721 ggagactgga caatggtgga cgaaaacttc tccacactca gcttgactca gtctgagctg
     3781 gagcacatct ccatggagtt ggcaagcaaa gggccccaca aatctcaagt tcagctgcgt
     3841 tatctgctgc acattttcat ggaggcagga tgtctggact ggtgtgttgt catcggcctg
     3901 attctcaaag aatcctccgt ggtcagtcag attcttggga ttgctcagtc ttcagagata
     3961 gatggagaga tgttacagaa cataaaagca gggctgcacg ccgtagaccg atgggcctct
     4021 acagactgcc ctggatataa gccattttta aacatcatta agccacaact acagaagctc
     4081 agtgagataa cggaagagtt ggtccagcct gacaccttcc agccaataac agtgggtaag
     4141 agtcctgaac agaccagccc ccgggcagag gagagcaggg gctcttctag ccatgggagc
     4201 atcactcaga gtgagaccgg gagtaacaac agcatggtca gccggaaaga agaggacaca
     4261 acacaagcag atgaagagga gccatttcag gatggggctt atgactgttc tgtgtcctga
     4321 caacgagcag gcagtattag tcacagcagc gtgcaccaga gcaccttgtg acctgctgag
     4381 tgacgtaaca ggtaaaagag cttggggcgg aactctttca taaagtgtta taatttaatg
     4441 aattcttcct ctaaatctct tcgactccat ttaaaaaaag aagtgtggta tcaaagcctc
     4501 tttttaagct gcagtagaaa gtaatgagca gtatatagat gcacatgcac atatgatatt
     4561 tgattttctt cacagtttgt agttgtagga attattcata acggatcgtt agtgtaggga
     4621 ttactctgcc ccaagtgagc ttattttttc actcctatgg cttatgtact ttctggttca
     4681 gcatgtctga ctggtttgtc ctgtgggtgg gttacctttc tttaaatgag tgctaaggcg
     4741 cttgctgcag ctcgtcagct gcctgagcaa ctgtctgctt ccgtgtggtg tggagtcagc
     4801 cggaccctta cttggtcctt cgaatcctgc gcttgtaagg aaggctcagt ggacagacac
     4861 cttgtgactt tggtacgttg ttcaccagca gtcctgggtt gatggaagcc agttacctgt
     4921 gacttaatgt gcctgtttta gcaagcttaa ttccttctag atcagtgtgg gcagaggggg
     4981 aggggttctt atcaattatg ctgacaccac taaattttgt atcaaagaac tgtatctttt
     5041 tgtgaatatt catgtaaata tactcaaagg cactgtccat atttttaagg tgtgtattat
     5101 aatctgtaag gtttacgctg gattctgcat gactatactc actcttggaa taaagacaag
     5161 actttcttct ttccaaaatg agcagtcatc atagaggaag acaggtttgt tggcccagct
     5221 gtaaagtagt agtcatccca ctgatcatga ggggaacagg ttttgtgcaa attaatggag
     5281 tttcttattt attgcttttg taaattgaat aaaaatgggc ttttatgtaa atagactgtg
     5341 ggatcctgta ttatcagcta ctaaaaatta ctttgtaaat tctttattat aaagtttaaa
     5401 aatattttat gtatttctag atgtgactta aattttagtt ttcatacatt atgaaagcag
     5461 aactacatat tcagttgctt cagactaaac acatacctac cacatgtaat tctaattatt
     5521 aataacagta ttaatttaga tagcttattt gtactgtgca atttgaacaa ggaatgcaat
     5581 gttatttttt ataaaatctt gtttattttt ataacaacaa tgtatttgaa gtggaccaaa
     5641 ttcgtaccac cgtgtaaaac agcctctctt ataatgcaga tgttgcttag aaatggaatt
     5701 cagccctctg ttcctgcctt ctaaactaaa gagatagact gcatcctctt aggcagtacc
     5761 tttagaggaa acctcagaat tattttgaaa ttatttcaaa tttcaccacc tagtaaaaat
     5821 tattgaattt agtaattact gttatttcct ttctacatta gaagtgcaat aattttatat
     5881 aataaaatcc ctgaatgggt gaaatatgtt gctattggta cctggtcctt ctggtgctac
     5941 ttttatttaa gtcattgtat caaatcacca ccttgttctg aattttaaaa tagagaataa
     6001 agtttcctat gtaagtagat gccgtgcagc aaaaaaaaca aaaactaagc tgaaatatct
     6061 tctgtcccat tccattaggg acaagagcca gcaattcttc tgtatctagt caatttctaa
     6121 tgtgactact cagttattaa agcagtgtta ccatcataag cagcagtggt gtttccagat
     6181 gtcttacatg ggtgctgctg agttcatcta actttggtgg tgagggcagt ataaggacga
     6241 gcatacggcc tctcatgcta accaagtgtt ccactactga gttatatccc acaagcccct
     6301 gccttttttt tttttttttt tttttttttt tttttttttt tgaggcagag ccttgcccaa
     6361 gctggacacc aatttgtaac tcttccttag ctgcccccat aactggtttt tacagccgtg
     6421 tgctgccata cccagtcata ggactatcac ctcacaatct taaaagcaga gtctggatta
     6481 gctaatgtga ctcctgtggt ttgagctggg aatgactcag ataaaataca tagtgtgtac
     6541 tgagtagaac taggaaacac caaagcaaga aatttggcaa gcttaataaa aattattctt
     6601 tggttgttgt atacttttta aaaaattgtg ttttgctgca ttgtttggtt taaaacatat
     6661 cacctgtaaa gccatatctt taatgaactt aaatattcag cataactatt tgaaagctaa
     6721 tatatatggt taaatttttt gctgatacca aaacatatca tttggagata caaacaactt
     6781 ttgcttgtaa ttaaagttgc tgctgcttct gtaatgtgta ttcccacccg ttggtaaagg
     6841 gtaataaaac tattacacaa acaaa
//
