LOCUS       NM_001305237            3337 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus rhophilin, Rho GTPase binding protein 1 (Rhpn1),
            mRNA.
ACCESSION   NM_001305237 XM_001069922 XM_216954
VERSION     NM_001305237.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3337)
  AUTHORS   Watanabe,G., Saito,Y., Madaule,P., Ishizaki,T., Fujisawa,K.,
            Morii,N., Mukai,H., Ono,Y., Kakizuka,A. and Narumiya,S.
  TITLE     Protein kinase N (PKN) and PKN-related protein rhophilin as targets
            of small GTPase Rho
  JOURNAL   Science 271 (5249), 645-648 (1996)
   PUBMED   8571126
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On or before Mar 5, 2015 this sequence version replaced
            XM_216954.8, XM_001069922.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments and orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.1722946.1,
                                           SRR26643287.18538.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               JAXUCZ010000007.1  109272715-109272889
            176-291             JAXUCZ010000007.1  109276132-109276247
            292-420             JAXUCZ010000007.1  109276962-109277090
            421-496             JAXUCZ010000007.1  109277199-109277274
            497-574             JAXUCZ010000007.1  109277986-109278063
            575-699             JAXUCZ010000007.1  109278414-109278538
            700-866             JAXUCZ010000007.1  109278625-109278791
            867-1060            JAXUCZ010000007.1  109278977-109279170
            1061-1217           JAXUCZ010000007.1  109279582-109279738
            1218-1325           JAXUCZ010000007.1  109279819-109279926
            1326-1520           JAXUCZ010000007.1  109280260-109280454
            1521-1597           JAXUCZ010000007.1  109280963-109281039
            1598-1744           JAXUCZ010000007.1  109281191-109281337
            1745-1906           JAXUCZ010000007.1  109281422-109281583
            1907-3337           JAXUCZ010000007.1  109282014-109283444
FEATURES             Location/Qualifiers
     source          1..3337
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..3337
                     /gene="Rhpn1"
                     /note="rhophilin, Rho GTPase binding protein 1"
                     /db_xref="GeneID:300030"
                     /db_xref="RGD:1305688"
     exon            1..175
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..2080
                     /gene="Rhpn1"
                     /codon_start=1
                     /product="rhophilin-1"
                     /protein_id="NP_001292166.1"
                     /db_xref="GeneID:300030"
                     /db_xref="RGD:1305688"
                     /translation="MILEERPDGQGTGEDSPRQQNDGSIRKGHDSFVQNQPGQLHSHR
                     ARLHQQISKELRMRTGAENLYRATSNTWVRETVALELSYVNSNLQLLKEELAELSCNA
                     DVDQPEGESVTIPMIPLGLKETKELDWATPLKELISEHFGEDGASYETEIQELEDLRQ
                     ATRTPSRDEVGLDLLAAYYSQLCFLDARFFSPARSPGLLFHWYDSLTGVPAQQRALAF
                     EKGSVLFNIGALHTQIGARQDCSCTEGTSQAAEAFQRAAGAFRLLRENFSHAPSPDMS
                     AASLSMLEQLMVAQAQECIFRGLLLRASATPDICPDQLQLAQEATQVATEYGLVHRAM
                     AQPPVRDYLPASWTNLARVKAEHFCALAHYHAAMALCESTSAKGELSRQEDIFQPSAT
                     CEPQGPTLPQHPEERRKLAKAHLKRAILGQEEALRLHTLCRVPRKVDLLQVVVTQALR
                     RSLTKYSELEREDDFFEAMEAPDIQPKTHQAPEVSIPSLSQVKVTDFFHRLGPLSVFS
                     TKNRWQLVGPVHMTRGEGGFGFTLRGDSPVLIAAVVPGGQAESAGLKEGDYIVSVNGQ
                     PCKWWKHVEVVTQLRSMGEEGVSLQVVSLLPGPEPRGTGPRRPALLWNQRECGFETPT
                     PAHTRPWPILGWSRKNKQSKSGSHPDPCTNRNCITCP"
     exon            176..291
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            292..420
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            421..496
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            497..574
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            575..699
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            700..866
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            867..1060
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1217
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1218..1325
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1520
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1521..1597
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1744
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1745..1906
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..3337
                     /gene="Rhpn1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaggggaca gtccgagcag cgcgctggtc ctccctgtag cgcgagggac ctgctgctcg
       61 cagcttctcg gggtcagcgt ccgagtgggc agcaatgatc ctcgaggaga ggccagatgg
      121 ccagggcact ggcgaggaca gccctcgtca gcagaacgac ggcagcatcc gtaagggcca
      181 tgactccttc gtgcaaaacc agcctggcca gctgcatagt cacagggctc ggctccacca
      241 gcagatcagc aaggagctgc gcatgcggac cggtgctgaa aacctctaca gagccacgag
      301 caacacctgg gtccgggaga cggtcgctct ggagctgagc tacgtcaact ccaacctaca
      361 actgctgaaa gaggagctgg cagagctgag ctgcaacgcg gatgtggacc agccagaggg
      421 tgagagtgtt actattccca tgatccccct gggcctgaag gaaaccaagg agttggactg
      481 ggccacaccg ctgaaggagc tgatctctga gcactttgga gaggacggtg cctcctatga
      541 gacagagatc caggaactag aagacctgcg gcaggctacg aggactccca gcagggacga
      601 ggtgggcctg gatctgcttg cagcctacta tagccagctc tgcttcctgg acgcacgttt
      661 cttcagtcct gccaggagcc cagggctact ctttcactgg tacgactcgc tcacgggggt
      721 cccggcacag cagcgggctc tggccttcga gaagggcagt gtactgttta acattggggc
      781 actccacacg cagatcggag cacggcagga ttgctcctgc accgagggca ccagccaggc
      841 cgccgaggct ttccagaggg ccgccggggc cttcagactc ctgagagaga acttctccca
      901 tgcgccaagc ccggacatga gcgccgcctc tctctccatg ctggagcagc tcatggttgc
      961 tcaggcccag gaatgcatct tcaggggcct cttgctgagg gcctcggcca cacctgacat
     1021 ctgtccagat caactgcagc tggctcagga agctacccag gtggcgaccg agtatgggct
     1081 tgtgcaccgg gccatggccc agccccccgt ccgagactac ctgcctgcct cctggactaa
     1141 cctggcacgt gtcaaggctg agcacttctg cgccctggcc cactatcacg cagccatggc
     1201 cctctgcgaa agcacctcag ccaagggtga actctcaagg caggaggaca tcttccagcc
     1261 ctcagctacc tgtgagcccc aaggtcccac actgccgcag cacccagaag agcgcaggaa
     1321 gcttgccaag gcccacctga agcgtgccat cctgggccag gaggaggcgc tgcggcttca
     1381 cactttgtgc agagtcccgc gcaaggtgga cctgctacag gttgtggtga ctcaggcact
     1441 gaggcgctcc ctgaccaagt actcagagct cgagcgtgag gatgacttct tcgaggctat
     1501 ggaggccccc gacatccagc ccaagactca ccaggcccca gaggtgagca tacctagcct
     1561 gtcgcaggtg aaggtgactg acttcttcca caggctggga cccctatccg tgttctcaac
     1621 caagaatcga tggcagttgg tcgggccggt gcacatgact cgaggagagg gaggtttcgg
     1681 gttcacgctg cggggagact cgccagtcct catcgctgcc gttgtccctg ggggtcaggc
     1741 tgagtctgct ggcctgaagg agggtgacta catcgtgtct gtgaatgggc agccttgcaa
     1801 gtggtggaaa cacgtagaag tggtcacgca gctgaggagc atgggcgagg aaggcgtgag
     1861 cctgcaggtc gtgtccttgc tgcccggccc cgaaccacgt ggcacgggac cccgacggcc
     1921 agcactgctg tggaaccaga gagaatgtgg ttttgagact ccgacgcctg cacacacccg
     1981 accctggccc atcctcggct ggagccgcaa gaataaacaa agcaagagtg ggagccaccc
     2041 tgacccctgc accaacagga actgtatcac ctgcccctga gctggacacc ccgtacccct
     2101 gtgtgtccag ggtggccgtg ggggccatac tcctgtgtac accatcctgt agccagcccc
     2161 agctagccag gtgtgcctag cgcattgccc tctactctgg gggaccatca ggctgcccct
     2221 gcctggctta gagatgtcta ttaaaaatgc tggtcagatg aggcaagtct gagtcagcta
     2281 ccagagccgt ggccacttta ccccacccga gatcttctca gtgtaatcca gacgcagtgc
     2341 ttacactatc ctcctgcagc aggcctctag gcccctgcca tgccccatct actcttcggc
     2401 tgcctgacta tcctcacatc cagtttctct gggcacgtac ccttatggtc ctatcctgac
     2461 tgcgcctggt tcatagtagc ccttctggtc accaccctcc cttgctggtt agtcagtttc
     2521 tctgtatgta agatcccagc aaagacattt tctctccagt ccccttatac tccccccaac
     2581 tttcaagccc ccctgtctcc cattccacct gcacccatgc aggtcctggc aggttcctca
     2641 gtaaggtagg ccctggactc cagaggcaca ggatgggggc accaggtaag aagcagtcct
     2701 aaactgtgca tggctgaagc catggagatg ctctccctca aaggccctgg aggttcagca
     2761 tggaaacaga aaggctgtat gtatctctct gtggtagaga atgcaagaaa ctctgggctc
     2821 agtccctgga actagaaaaa aacagaaaca aaaaaattag agggggagat tgctctctgt
     2881 gaccaccagg gggcagtgtc actcattcat gcagccctag gaggctgcag ctcttccaac
     2941 ccccacgaat ctgagaatcc gtggacagcc caggaaagag aagcatccag ctcggtactc
     3001 agcaacccac ccacactcat cctccagctt ctgcccaggg gctcccaggt gagagcacct
     3061 agagtctgtg ctccagattg gcctacacag tccagggctc tgccgcccat caccctgtgc
     3121 agacatctgt gtcaaggtcc agcgggtaaa tgtagtgttt aagcacgtga gtccggaaga
     3181 tccaggtaca gctttcttct gacgtaggag aggctcccag gggatccagg agtgtccctt
     3241 atcactcacc tgggacaatc tccaactcag cagaatgacc aaggccactc aggctcaaca
     3301 cttgctaatt ttattaataa aactgtacgt caaggaa
//
