LOCUS       NM_182825               1260 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus RHEB like 1 (Rhebl1), mRNA.
ACCESSION   NM_182825 XM_345869
VERSION     NM_182825.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1260)
  AUTHORS   Yuan,J., Shan,Y., Chen,X., Tang,W., Luo,K., Ni,J., Wan,B. and Yu,L.
  TITLE     Identification and characterization of RHEBL1, a novel member of
            Ras family, which activates transcriptional activities of NF-kappa
            B
  JOURNAL   Mol Biol Rep 32 (4), 205-214 (2005)
   PUBMED   16328882
REFERENCE   2  (bases 1 to 1260)
  AUTHORS   Tabancay,A.P. Jr., Gau,C.L., Machado,I.M., Uhlmann,E.J.,
            Gutmann,D.H., Guo,L. and Tamanoi,F.
  TITLE     Identification of dominant negative mutants of Rheb GTPase and
            their use to implicate the involvement of human Rheb in the
            activation of p70S6K
  JOURNAL   J Biol Chem 278 (41), 39921-39930 (2003)
   PUBMED   12869548
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Feb 3, 2022 this sequence version replaced NM_182825.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY327411.1, SRR26360186.1102685.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680414, SAMN06680416
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-226               JAXUCZ010000007.1  131908966-131909191 c
            227-298             JAXUCZ010000007.1  131908312-131908383 c
            299-366             JAXUCZ010000007.1  131907560-131907627 c
            367-449             JAXUCZ010000007.1  131907202-131907284 c
            450-506             JAXUCZ010000007.1  131907056-131907112 c
            507-554             JAXUCZ010000007.1  131906807-131906854 c
            555-636             JAXUCZ010000007.1  131905989-131906070 c
            637-1260            JAXUCZ010000007.1  131905207-131905830 c
FEATURES             Location/Qualifiers
     source          1..1260
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1260
                     /gene="Rhebl1"
                     /note="RHEB like 1"
                     /db_xref="GeneID:359959"
                     /db_xref="RGD:727778"
     exon            1..226
                     /gene="Rhebl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             175..726
                     /gene="Rhebl1"
                     /note="rheb-like protein 1; Ras homolog enriched in brain
                     like 1; ras homolog enriched in brain-like protein 1"
                     /codon_start=1
                     /product="GTPase RhebL1"
                     /protein_id="NP_877977.1"
                     /db_xref="GeneID:359959"
                     /db_xref="RGD:727778"
                     /translation="MPLVRYRKVAILGYRSVGKTSLAHQFVEGEFLKGYDPTVENTYS
                     KTVTLGKDEFHLHLVDTAGQDKYSILPYSFIIGVHGYVLVYNVTSLRSFQIVKNLYQK
                     LQEGHGKTRLPVLLVGNKADLSADREVQAVEGKKLAESWGATFMESSARDNQLIQDIF
                     IRVIQEIARVENSYGQDRRCCLM"
     exon            227..298
                     /gene="Rhebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            299..366
                     /gene="Rhebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            367..449
                     /gene="Rhebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            450..506
                     /gene="Rhebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            507..554
                     /gene="Rhebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            555..636
                     /gene="Rhebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            637..1260
                     /gene="Rhebl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgatcacgt gggctgcccg gggcgcgcgg cttgttttgg tttttccttg cgtttgccgg
       61 gtgagctccg gtgagctact gtccttcccc gtgtccaccc aggcctgcac ctcggctgat
      121 ctttgggctc cctcagcccg cactctgacg agccccgcgg ggcggcgtcc tgtcatgccg
      181 ctagtgcgct acaggaaggt ggccatcctg gggtaccgct ccgtagggaa gacatctttg
      241 gcacatcaat ttgtggaagg ggagttcctg aaaggctacg atcctacagt ggagaatact
      301 tacagcaaga cagtgactct tggcaaagat gagtttcacc tacatctagt ggacacagca
      361 gggcaggata agtacagcat tctgccctat tccttcatca ttggggtcca tggttacgtg
      421 cttgtgtaca acgttacctc cctgcgcagc ttccaaatcg ttaagaacct gtaccaaaag
      481 ctacaggaag gccatggtaa aactcgactg ccagtgctgc ttgtggggaa caaggcagat
      541 ctctctgcag acagagaggt gcaggcagtt gaagggaaga agctagcaga gtcctggggt
      601 gcaacattta tggagtcatc tgcacgggat aatcagctaa ttcaggacat cttcatcaga
      661 gtcatccagg agattgcccg tgtggagaat tcttatggac aagaccgccg atgctgtctt
      721 atgtgaactc ttggcatgga ataactgccc tgtttcggcc acaggcattg accaacctgc
      781 agcagtgggg tcgaccctca ggacttaagt actagggttg ccaactatgt ccttactcct
      841 ctgggcacac agtaggggac ccttattttt gcacactcat cccaggttct ggtaacctgg
      901 atgttaatgt ttacaaaggg gcaaaacgtc tcagggacac tggcttctaa ctccttgttt
      961 tcctaaacga atttttatag tctgtacagt tgggatgagt cttgggcatt gattaccgag
     1021 gatctgccct cctgggtata ttttgggtgt tggttgggta agggtgttgg tcacttggca
     1081 gttcagaagt agaactgtcc gggctgggga tttagctcag tggtagagcg cttacctagg
     1141 aagcgcaagg tcctgggttc ggtacccagc tccgaaaaaa agaaccaaaa aaaaaaaaaa
     1201 aaagaagtag aactgtctac tggggtaact gtatatttcc aaataaactg agaaatcttt
//
