LOCUS       NM_022505               1509 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus Rh blood group, D antigen (Rhd), mRNA.
ACCESSION   NM_022505 XM_001067788
VERSION     NM_022505.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1509)
  AUTHORS   Goossens,D., Trinh-Trang-Tan,M.M., Debbia,M., Ripoche,P.,
            Vilela-Lamego,C., Louache,F., Vainchenker,W., Colin,Y. and
            Cartron,J.P.
  TITLE     Generation and characterisation of Rhd and Rhag null mice
  JOURNAL   Br J Haematol 148 (1), 161-172 (2010)
   PUBMED   19807729
REFERENCE   2  (bases 1 to 1509)
  AUTHORS   Huang,C.H. and Peng,J.
  TITLE     Evolutionary conservation and diversification of Rh family genes
            and proteins
  JOURNAL   Proc Natl Acad Sci U S A 102 (43), 15512-15517 (2005)
   PUBMED   16227429
REFERENCE   3  (bases 1 to 1509)
  AUTHORS   Westhoff,C.M., Schultze,A., From,A., Wylie,D.E. and
            Silberstein,L.E.
  TITLE     Characterization of the mouse Rh blood group gene
  JOURNAL   Genomics 57 (3), 451-454 (1999)
   PUBMED   10329015
REFERENCE   4  (bases 1 to 1509)
  AUTHORS   Kitano,T., Sumiyama,K., Shiroishi,T. and Saitou,N.
  TITLE     Conserved evolution of the Rh50 gene compared to its homologous Rh
            blood group gene
  JOURNAL   Biochem Biophys Res Commun 249 (1), 78-85 (1998)
   PUBMED   9705835
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF531096.1.
            
            [WARNING] On May 2, 2024 this sequence was replaced by NM_022505.3.
            
            On or before Jun 25, 2006 this sequence version replaced
            XM_001067788.1, NM_022505.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF531096.1, FQ234604.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN06680412
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1509
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1509
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /note="Rh blood group, D antigen"
                     /db_xref="GeneID:60414"
                     /db_xref="RGD:620451"
     exon            1..180
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     CDS             36..1304
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /note="Rhesus blood group CE and D; erythrocyte membrane
                     glycoprotein Rh30"
                     /codon_start=1
                     /product="blood group Rh(D) polypeptide"
                     /protein_id="NP_071950.1"
                     /db_xref="GeneID:60414"
                     /db_xref="RGD:620451"
                     /translation="MGSKYPRSLRCCLPLWAFGLQVTFILLFYFLIGQDPIQADHKFM
                     AIYQVIQDLTLVAALGFGFLSSSFRRHGWSSVAFSFFMLALGVQGTILLDYFLNWVLD
                     WNMIKNPFSPFLSIQRATISTLPLLISAGAVLGKVNLVQLAVMVLVEAMTFGAIRVAD
                     KKVFRIEDHIIMMYGHVFGAYFGLTVAWWLSKSLPRRRHENAQTEKVQMTTSSSLFAM
                     LGTLFLWIFWPSINSALLEGTKKKNAVFNTYYALAVSTVTATSMSALSHPKGKINMVH
                     IHNAVLAGGVAVGAPSCLISSPWIAMVLGLTAGLISIWGAKCPQVCLSDLLLNPSGIH
                     YTFGLPGLLGALTYYCLHIIAESRPSNLWIVTQTITDVGALSFAMAMGMVTGLLTGCL
                     LSVKVWRAPHAVKYFDDQAFWEFPHLAVEF"
     exon            181..367
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     exon            368..530
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     exon            531..693
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     exon            694..857
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     exon            858..995
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     exon            996..1123
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     exon            1124..1203
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     exon            1204..1277
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1492
                     /gene="Rhd"
                     /gene_synonym="Rh; Rhced"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctgacaga acttgggcac agcggcagac acaagatggg ctctaagtac ccaaggtccc
       61 tccgctgctg cctgcccctg tgggccttcg ggctacaggt gacttttatc ctcctcttct
      121 attttctcat cggccaagac cctatccagg cagatcacaa gttcatggcg atctatcaag
      181 tcatccagga tttgaccctt gtggcagcct tgggtttcgg cttcctgtcc tcatcctttc
      241 ggagacacgg ctggagcagt gtggccttca gcttcttcat gttggccctt ggggtacagg
      301 ggacaatctt gctggactat ttcctgaatt gggtcctcga ctggaacatg atcaagaatc
      361 cgttcagtcc gtttctcagc atccagagag ctaccataag caccttaccg ctgctgatct
      421 cagcgggcgc tgtcttgggg aaggtcaact tggtgcagct ggccgtgatg gtgctggtgg
      481 aagctatgac ctttggtgcc atcagagtcg ctgacaagaa ggtcttcaga attgaagacc
      541 acataatcat gatgtacgga cacgtgtttg gggcctattt tgggctgact gtggcatggt
      601 ggctttccaa gtctctgccc aggagaaggc atgagaacgc ccagacagaa aaggttcaga
      661 tgaccacgag ctccagtctg tttgccatgc tgggcaccct cttcttgtgg atattctggc
      721 caagtatcaa ctctgctctc ctggaaggga caaagaaaaa gaacgcagtg ttcaacacct
      781 actacgccct ggcagtcagc acagtgacag ccacctccat gtccgccctg agtcacccca
      841 aagggaagat caacatggtt cacatccaca acgcagtgct ggctgggggt gtggctgtcg
      901 gtgccccgag ttgcctgatt tcttctcctt ggattgctat ggtcctgggc ctcacagctg
      961 ggttgatctc catctgggga gccaagtgtc cacaggtgtg tttgagcgac ttgctgctga
     1021 accccagtgg gatccactac accttcggct tgcccggcct gctcggagca ctcacctact
     1081 actgcctcca tataatagcc gagtccaggc cctccaatct ctggattgtc acccaaacga
     1141 tcactgacgt cggggctctc agctttgcta tggcgatggg aatggtgact ggactgctga
     1201 caggttgtct cctaagtgtc aaagtgtgga gggctcccca tgcagtcaag tactttgatg
     1261 atcaggcttt ctgggagttc ccccacttgg ctgtcgaatt ttaagcaaat ccatctgaga
     1321 acgaggctga gcacggcgag ccctccgttc accttccatt tgtctgcatc atgtgttaca
     1381 agaaaggctt ccgagtgatg gtcgaagttt aaatatgttc gctttcatga cagatacgat
     1441 caatactttt ggctgaagac acctcattaa agttctggtc taattctacg caaaaaaaaa
     1501 aaaaaaaaa
//
