LOCUS       NM_001013875            1874 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus rhomboid domain containing 3 (Rhbdd3), mRNA.
ACCESSION   NM_001013875 XM_214071
VERSION     NM_001013875.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1874)
  AUTHORS   Liu,J., Liu,S., Xia,M., Xu,S., Wang,C., Bao,Y., Jiang,M., Wu,Y.,
            Xu,T. and Cao,X.
  TITLE     Rhomboid domain-containing protein 3 is a negative regulator of
            TLR3-triggered natural killer cell activation
  JOURNAL   Proc Natl Acad Sci U S A 110 (19), 7814-7819 (2013)
   PUBMED   23610400
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081912.1.
            
            On Apr 20, 2005 this sequence version replaced XM_214071.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081912.1, SRR8487230.142987.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1874
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..1874
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /note="rhomboid domain containing 3"
                     /db_xref="GeneID:289753"
                     /db_xref="RGD:1311827"
     exon            1..262
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /inference="alignment:Splign:2.1.0"
     exon            263..466
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /inference="alignment:Splign:2.1.0"
     exon            467..503
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /inference="alignment:Splign:2.1.0"
     exon            504..693
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /inference="alignment:Splign:2.1.0"
     CDS             546..1703
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /codon_start=1
                     /product="rhomboid domain-containing protein 3"
                     /protein_id="NP_001013897.1"
                     /db_xref="GeneID:289753"
                     /db_xref="RGD:1311827"
                     /translation="MHAWDPPASLSRALPLASSVLMLLLSCLWLLGAGPSLRLAPELL
                     TEPWQVHRLLTHALGHTALPGLLLSLLLLPTLGWWQECHLGTLRFLHNSAVLALATGL
                     LAVLLAGLGLSSAAGGCGYMPVHLAMLAGQSYYPGWPQRTLPPWLLPWLLLALTLLLS
                     SEPPFLQLLCGLLAGLAYAAGAFRWLELSERRLQVLQEGVLCRTLAGCWPLKLLPTPG
                     SLGELPVTYPAGVRPATPRPPYLASSSSWPHTDGFAQLPPGLGPGQLTWKNSERDLDW
                     AGPSFASATPMWAALDEQMLQEGIQASLLDVSVQGSQNTLWSPKPSVSSLRLQQLQHM
                     GFPTEQAAVALAATGRVEGAVSLLVEGLVDTEALVTEERSGPAHCKDTGVS"
     exon            694..1077
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /inference="alignment:Splign:2.1.0"
     exon            1078..1240
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1525
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /inference="alignment:Splign:2.1.0"
     exon            1526..1846
                     /gene="Rhbdd3"
                     /gene_synonym="RGD1311827"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggtccgtc tgcttgggag ggaggccggg aatgccgcgc ccgaccccag taacggtcgg
       61 agtccagaag ccctataatc atccatcctt caactcatac ccttgtctta acagaaaact
      121 caggcccaag aaattgagta cttcccctag agttacaaag ctgaatccga cccagacccc
      181 gggactcccc tctctgtgct ccacccggaa gcttctccac tgtccttgat ttcccattct
      241 gtcctcctgg cttcccagta agatatggtt ggaggagtgt taccggcttg cctatgatgt
      301 atgagaccct agtttccatt cctatcgcca agaaagagaa gagactggtc cagaggactc
      361 gaggcccagt tctgtatgtc catggacctg tcccttagtg cccagggatg gaatggttgt
      421 gagaaggtgc aagaggaagc ttcattttag gtgaccctgc ctccagtact gggaaacaaa
      481 tccagctgcc tatgtatggc tagcatccag cctcaggacc acctttgacc accatcaaca
      541 aagctatgca tgcctgggac ccccctgcct cactgtcccg ggcactaccc ctcgcttcct
      601 cggtcctgat gctgctgctg agctgcctgt ggttgctggg ggctggcccc agcctcaggt
      661 tggctccaga gctgctaacg gaaccctggc aggtgcaccg gctgctgacc catgctctgg
      721 gccacactgc actgcctggc ctgctcctga gcctgctgct cctgcccact ctgggctggt
      781 ggcaggagtg tcatctgggc actctgcgct tcctgcacaa ctccgccgtg cttgccctgg
      841 ctactgggct gctggctgtg ctgctggcag gccttggcct gtccagtgca gctggaggct
      901 gtggatatat gcctgtccat ctagccatgc tggcagggca gagttactac ccaggatggc
      961 ctcagaggac cctgccacca tggctgctac catggctgct gctggccctg accctgctgc
     1021 tcagctctga gccacccttc ctgcagctcc tttgtggcct tcttgctggc ctagcctatg
     1081 ccgctggggc cttccggtgg ctggagctct cagagcggag actgcaggtg ttacaggaag
     1141 gtgtcctttg caggactctg gccgggtgct ggccactgaa actccttccc accccaggca
     1201 gtctgggtga gctgcctgtc acttatcctg ctggagtaag gcctgccacc cctagacctc
     1261 cttacctggc ttcctcaagc tcctggcctc acactgatgg ctttgctcag cttccaccag
     1321 gcctggggcc tggacagctg acctggaaga actcggagag ggacttggac tgggctgggc
     1381 ccagctttgc ttcagcaaca ccgatgtggg cagccctaga tgagcaaatg ctacaggaag
     1441 ggatccaggc ctcacttctt gatgtgtcag tccagggttc ccagaacact ctgtggtcac
     1501 caaagccctc tgtgtcttct ctaaggcttc agcagctaca gcatatggga ttccccactg
     1561 agcaggctgc ggtggccttg gcagctacag ggcgtgtaga gggggcagtg tccctgctgg
     1621 tggaagggct agtggatacc gaggccctag tgactgagga gaggagtggt ccagcccact
     1681 gcaaggacac tggggtctca tagtctaaga agagagtaga cctggcctga gtccttacct
     1741 ggtctcctga gggcttggtg gggtcttgaa agcatcctgg ggcaggagca ggccccacca
     1801 tgttcccctg gtactttgta agaataaaag ctggtgtgct tttcaaaaaa aaaaaaaaaa
     1861 aaaaaaaaaa aaaa
//
