LOCUS       NM_001012347            1364 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus regulator of G-protein signaling 7 binding
            protein (Rgs7bp), mRNA.
ACCESSION   NM_001012347 XM_215473
VERSION     NM_001012347.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Aguado,C., Orlandi,C., Fajardo-Serrano,A., Gil-Minguez,M.,
            Martemyanov,K.A. and Lujan,R.
  TITLE     Cellular and Subcellular Localization of the RGS7/Gbeta5/R7BP
            Complex in the Cerebellar Cortex
  JOURNAL   Front Neuroanat 10, 114 (2016)
   PUBMED   27965545
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  AUTHORS   Ostrovskaya,O., Xie,K., Masuho,I., Fajardo-Serrano,A., Lujan,R.,
            Wickman,K. and Martemyanov,K.A.
  TITLE     RGS7/Gbeta5/R7BP complex regulates synaptic plasticity and memory
            by modulating hippocampal GABABR-GIRK signaling
  JOURNAL   Elife 3, e02053 (2014)
   PUBMED   24755289
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1364)
  AUTHORS   Jia,L., Linder,M.E. and Blumer,K.J.
  TITLE     Gi/o signaling and the palmitoyltransferase DHHC2 regulate
            palmitate cycling and shuttling of RGS7 family-binding protein
  JOURNAL   J Biol Chem 286 (15), 13695-13703 (2011)
   PUBMED   21343290
REFERENCE   4  (bases 1 to 1364)
  AUTHORS   Beaulieu,J.M. and Gainetdinov,R.R.
  TITLE     The physiology, signaling, and pharmacology of dopamine receptors
  JOURNAL   Pharmacol Rev 63 (1), 182-217 (2011)
   PUBMED   21303898
  REMARK    Review article
REFERENCE   5  (bases 1 to 1364)
  AUTHORS   Grabowska,D., Jayaraman,M., Kaltenbronn,K.M., Sandiford,S.L.,
            Wang,Q., Jenkins,S., Slepak,V.Z., Smith,Y. and Blumer,K.J.
  TITLE     Postnatal induction and localization of R7BP, a membrane-anchoring
            protein for regulator of G protein signaling 7 family-Gbeta5
            complexes in brain
  JOURNAL   Neuroscience 151 (4), 969-982 (2008)
   PUBMED   18248908
REFERENCE   6  (bases 1 to 1364)
  AUTHORS   Anderson,G.R., Lujan,R., Semenov,A., Pravetoni,M., Posokhova,E.N.,
            Song,J.H., Uversky,V., Chen,C.K., Wickman,K. and Martemyanov,K.A.
  TITLE     Expression and localization of RGS9-2/G 5/R7BP complex in vivo is
            set by dynamic control of its constitutive degradation by cellular
            cysteine proteases
  JOURNAL   J Neurosci 27 (51), 14117-14127 (2007)
   PUBMED   18094251
REFERENCE   7  (bases 1 to 1364)
  AUTHORS   Drenan,R.M., Doupnik,C.A., Boyle,M.P., Muglia,L.J., Huettner,J.E.,
            Linder,M.E. and Blumer,K.J.
  TITLE     Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP,
            a novel membrane anchor for the RGS7 family
  JOURNAL   J Cell Biol 169 (4), 623-633 (2005)
   PUBMED   15897264
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC089977.1.
            
            On Feb 18, 2005 this sequence version replaced XM_215473.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089977.1, SRR8487226.71706.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760384 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q13"
     gene            1..1364
                     /gene="Rgs7bp"
                     /gene_synonym="R7bp; RGD1309360"
                     /note="regulator of G-protein signaling 7 binding protein"
                     /db_xref="GeneID:294715"
                     /db_xref="RGD:1309360"
     exon            1..538
                     /gene="Rgs7bp"
                     /gene_synonym="R7bp; RGD1309360"
                     /inference="alignment:Splign:2.1.0"
     CDS             374..1147
                     /gene="Rgs7bp"
                     /gene_synonym="R7bp; RGD1309360"
                     /note="R7 binding protein; R7 family-binding protein"
                     /codon_start=1
                     /product="regulator of G-protein signaling 7-binding
                     protein"
                     /protein_id="NP_001012347.1"
                     /db_xref="GeneID:294715"
                     /db_xref="RGD:1309360"
                     /translation="MSSAPNGRKKRPSRSTRSSIFQISKPPLQSGDWERRGSGSESAH
                     KTQRALDDCKMLVQEFNTQVALYRELVISIGDVSVSCPSLRAEMHKTRTKGCEMARQA
                     HQKLAAISGPEDGEIHPEICRLYIQLQCCLEMYTTEMLKSICLLGSLQFHRKGKEASG
                     GAKSLDSKIEENAETPALEDSLSSPLDSQQQSWQVATDIENTERDMREMKNLLSKLRE
                     TMPLPLKNQDDSSLLNLTPYPMVRRRKRRFFGLCCLVSS"
     exon            539..705
                     /gene="Rgs7bp"
                     /gene_synonym="R7bp; RGD1309360"
                     /inference="alignment:Splign:2.1.0"
     exon            706..836
                     /gene="Rgs7bp"
                     /gene_synonym="R7bp; RGD1309360"
                     /inference="alignment:Splign:2.1.0"
     exon            837..984
                     /gene="Rgs7bp"
                     /gene_synonym="R7bp; RGD1309360"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1055
                     /gene="Rgs7bp"
                     /gene_synonym="R7bp; RGD1309360"
                     /inference="alignment:Splign:2.1.0"
     exon            1056..1351
                     /gene="Rgs7bp"
                     /gene_synonym="R7bp; RGD1309360"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggaaactcg gagccgcccg gcggcgcgtt cctcctcgct cagcctgtca atccatgccg
       61 agaggaaggc ggtgcaagcc cgcgccagca gcgtccagct cccgggacag ggccggcaat
      121 gctgctgagc agaacttgat cgcgcctctc cgtcgctgct agcggaagcg atgctgtacc
      181 gcacaggcag cgcttccccg gctctccttc aagctgaagg ttacccaccc gcgcagccag
      241 ccgcaacctt gtgagccgcg cgcgcctcag gtcccggctc tggctgctcc gcggcggcgt
      301 gcaggggcaa ccaccgggcc gcccgcgccg gggcgcactg caccagcggc ttcggcttcg
      361 tggatgtgta tgcatgagtt ctgcaccgaa tgggcgcaaa aagcgcccca gccggtccac
      421 ccgctcctcg atcttccaga tcagcaagcc tccgctgcag agcggagatt gggagcgcag
      481 gggcagtggc tccgaaagcg cccacaaaac ccaacgagcc ctggacgact gcaagatgct
      541 tgtccaagag ttcaacacgc aagtggccct gtaccgagag ttggtcattt ctattgggga
      601 cgtctcagtc agctgcccct ctctgcgagc ggaaatgcac aagacaagga ccaaaggctg
      661 tgaaatggcc cgacaggcgc accaaaagct ggctgccatc tcaggcccgg aagatggtga
      721 gatccatccc gaaatctgcc ggctttacat ccagctgcag tgttgcctgg agatgtacac
      781 aacggagatg ctgaagtcca tctgtctgct ggggtctctt cagttccatc gaaaaggaaa
      841 agaagctagt gggggagcaa agagtctgga cagtaaaatt gaagagaatg ctgaaacgcc
      901 tgccctggag gactccttgt catcccctct agatagccag cagcagtcct ggcaggtggc
      961 cacagatatt gaaaacactg aaagagacat gcgagaaatg aaaaaccttc ttagcaaact
     1021 cagggaaacg atgcctttac cgctgaaaaa tcaagatgac agcagccttc tgaatctaac
     1081 tccctacccc atggtcagaa gacggaagag aaggttcttc gggttatgtt gtcttgtctc
     1141 cagctaggtg ggtcttctgg aaactcaccg ccaagatcac ctgaaaaaca ccacagaacc
     1201 ggaagacctc cacaccgcag aacactgaga atggttttga ccacgttttc taggcttcct
     1261 tattactttt atctgcctct ccccgccctt ttaaatgatt tcacacttga aagcagctgc
     1321 catcaaggag aggaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
