LOCUS       XM_006241548            5176 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus regulator of G-protein signaling 22
            (Rgs22), transcript variant X1, mRNA.
ACCESSION   XM_006241548
VERSION     XM_006241548.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006241548.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006241548.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5176
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5176
                     /gene="Rgs22"
                     /note="regulator of G-protein signaling 22; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 10 ESTs, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 38 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:500853"
                     /db_xref="RGD:1565493"
     CDS             132..3905
                     /gene="Rgs22"
                     /codon_start=1
                     /product="regulator of G-protein signaling 22 isoform X1"
                     /protein_id="XP_006241610.1"
                     /db_xref="GeneID:500853"
                     /db_xref="RGD:1565493"
                     /translation="MPERRLSAEPPEVTEEEFENYLATDNFLVDYFNEFLSLPTFSEA
                     IRFNVDYGVFEVINDAPQLLEKQLKKILQNQQPRNPIYDVVRKGKSDSKAKQKSVPCE
                     DEAINVNYTIMCLKREQGINWIKRKRLPAFLESDCYFEYRLAKLISQATWSSSGMNFT
                     VGTNFSPWILRKPPTPPHASTEEDNSGIMKTFYVSLGQASYTQTKDWFTLAKESEKTV
                     TTFSLPCCLPHHESASSVVATVSEIFDDGIHPRTTNGLSKTSKIVSEPEEEEGSISMK
                     DTPSQALLRIYLERKGEDRNLTVHFSSFDEFLNAYIIFILREAIHHITGQSLSDTPGY
                     VNYYKVAHVIFDKAKPVPSQKATVSPPVEVVQETSEDRLEENVSLSSESESVGPESRA
                     DWCISHKTYDIGNRREFERFKKFLKGTLGERYWWLWMDIERLKVLKDPGRHQRHLEKM
                     KKCYLVSSGERYLSAEILSKFKLMNGSWWTEDHLKNIQIEVLKPLLLYWAPRFCVTHS
                     VSAKNASAELKFWRFRQEKPRKDVDPFPQMATLLPLRPKSCIPQTPEVQGEEIGLFQP
                     SKSKKLSKMNAGTQKFGRNESVRPVSSKDDRVEKGSKRLPESTTVVRLTSFTDISECL
                     KPQLERKYTYTEKMNVKTVSNVGALGGFDMENLLQSLYVENRAGFFFTKFCENSGNKL
                     WKHSVYFWFDLQAYHQLFYQETLEPFKVCKQAQYLFATYIAPSASLDVGLHPEEKKDI
                     YIKIQPPFEDLFDTAEEFILLNLLEPWTQMVMSDQVSYRKVELQEETRQLDSTSFRKL
                     HALHKEAVSKKAEDTAGSVTAALSLSDISKQTEYWLNVPEEYKYFTFNDLLNNKLEFE
                     HFRQFLESHSSSIDLMCWIDIEQFRRIIFKDQKQREAKSIYIKNKYLNKKYFFGPRSP
                     ASLHQQNQIMLLSGGWGKILHEQLDASVLVEIQKHVLNRLENVWLPLFLSSEQFASRQ
                     KIKIRMKDIADELLLQRHDRKIGVWKPVESKWISSSCEIIAFRKALLNPVIARQFQRF
                     VALKGDLLENGVLFWQEVQKFKDLCHSHCEESIIHKKITTIINCFINSCIPPALQIDI
                     PVEQAQKIIEHRKELGPYVFREAQMTIFGVLFKFWPQFCEFRKNLTDEKIMSVLERRQ
                     EYKQKRKTSDIEEDKAAKSGVKQYASTTGSLTKPTLGSESLLVLQSYGRQPTWCYSKY
                     IEALEQERILLKIQEEVERKMFTGTSSFTNLLKPSTGSALSLKKNVSPHSIQR"
ORIGIN      
        1 ccaggcgcct ctgctttgtg cagctctatg gcaacagcag gcagcacaga acgggcattc
       61 cctggccgcg cgccgccggg cggcggtcgc tccccagaca gcggggccgg gcagctgggc
      121 ccccggacaa catgccggaa aggcggctct cggcggagcc gccagaagtt acagaagaag
      181 aatttgaaaa ttacttggca acagacaact tccttgtgga ctactttaat gagttcttaa
      241 gtcttcctac cttttcagag gcaattagat ttaatgtgga ctacggagtt tttgaagtaa
      301 ttaatgatgc accacaactt ctggaaaagc aactgaaaaa aattctgcaa aaccagcaac
      361 cgcggaatcc catctatgat gttgtaagaa aagggaagag tgacagcaaa gctaagcaaa
      421 agagtgtccc ctgtgaagac gaggccatca atgtcaacta caccatcatg tgtctcaagc
      481 gtgaacaagg tattaattgg atcaaaagga aaagacttcc ggcatttctg gaaagtgatt
      541 gctactttga atacaggcta gccaagttga tctcgcaagc gacatggagc agctcaggca
      601 tgaatttcac agtaggtaca aatttttctc cgtggatcct gagaaaaccg cccactccac
      661 ctcatgccag cactgaagag gacaattccg ggattatgaa gacgttctac gtttctctgg
      721 gccaggcctc ctatactcaa acaaaagact ggtttacact cgccaaggag agtgagaaga
      781 cagtgacgac attttcatta ccctgctgtt taccccatca cgaaagtgca tcctcagttg
      841 ttgccacggt ttctgagatt tttgatgatg gaattcaccc caggacaaca aacggcctgt
      901 ctaaaacctc taaaatagtt tccgagccgg aggaagaaga aggttctata tcaatgaaag
      961 atacaccttc tcaagctcta ctgagaatat acctggagag gaagggcgag gacagaaacc
     1021 tgaccgtgca cttctcatcg tttgacgaat tcctaaatgc ctacatcatc tttatcttga
     1081 gagaagccat ccatcatatc acaggccagt cccttagtga cactccaggc tatgtcaact
     1141 actataaagt agcccatgtg atatttgata aagccaagcc tgtgcctagc cagaaggcta
     1201 cagtttcacc ccctgttgaa gttgtacaag aaacctcaga agatagattg gaggaaaatg
     1261 taagtttaag ttcagagagt gagagtgttg ggcctgagag cagggcagac tggtgtattt
     1321 ctcacaaaac ctatgacatt ggcaacagaa gggaatttga aagatttaag aagtttctaa
     1381 aaggcacatt aggagagagg tactggtggc tgtggatgga catagagagg ctgaaagttc
     1441 ttaaggaccc tggaagacat caaagacatc ttgagaaaat gaaaaaatgc taccttgtga
     1501 gcagtgggga gcgctacctt tctgcagaaa ttttatcaaa gtttaagctg atgaatggat
     1561 cctggtggac agaagaccat ttgaaaaaca tccagattga ggttttaaaa cctctgcttc
     1621 tgtattgggc accaagattt tgtgtaactc attcagtttc tgcaaaaaat gctagtgctg
     1681 agctgaagtt ctggcgcttc cgtcaggaga agccaaggaa ggatgttgac cctttcccac
     1741 agatggccac tctcctgcca ttaagaccga agtcctgcat tccacagacc cccgaggtcc
     1801 agggagaaga aatcggttta tttcaaccat ctaaatctaa gaaattatca aaaatgaatg
     1861 cagggactca aaaatttggg agaaatgagt ctgtgcgccc agtttcttct aaggacgaca
     1921 gggttgagaa agggtcaaag aggctaccag agagcaccac ggtggtccgc ttgacatctt
     1981 ttacggacat ctccgagtgt ctgaagcccc aactggagag gaaatacact tacacagaga
     2041 agatgaatgt taaaactgta tcaaatgttg gagccttggg aggatttgac atggaaaact
     2101 tgttgcaatc tttatacgta gaaaacagag ctggattctt ctttaccaaa ttttgcgaga
     2161 attcagggaa caagctgtgg aagcacagtg tgtacttttg gtttgaccta caggcttatc
     2221 accagctgtt ctaccaagaa acgctcgaac ctttcaaagt gtgcaagcaa gcccaatatc
     2281 ttttcgccac atacatcgct ccatcagcca gtctcgatgt tggactccat ccggaagaga
     2341 agaaagacat ttacataaaa atacagcccc cattcgaaga cctttttgac acagcagagg
     2401 agtttatcct tctcaacctt ctggaaccct ggacacagat ggtgatgtca gaccaggtgt
     2461 cttacagaaa ggtggaacta caagaagaga ctcggcagct ggattccaca tccttcagaa
     2521 agctacatgc tttgcataaa gaagcagttt ccaagaaggc tgaggacact gccgggtctg
     2581 tgacggctgc actgtcactc tcagacatct ctaaacagac agagtattgg ctgaatgttc
     2641 ctgaggaata caagtacttt acctttaatg acttacttaa caacaaacta gaattcgaac
     2701 atttccgtca atttctagag tctcattctt caagtatcga ccttatgtgt tggatagata
     2761 tcgaacagtt ccgaagaatc atttttaaag accaaaagca aagagaggca aagtctatat
     2821 acattaaaaa caagtacctt aataaaaaat atttcttcgg acccagaagt ccagcttctt
     2881 tgcatcaaca gaaccagata atgcttctga gtggtggctg gggcaagatt cttcatgagc
     2941 agcttgacgc atctgtgctg gtagagatcc agaagcacgt cttgaatagg ctggaaaacg
     3001 tgtggctgcc attgtttctt tcgagtgagc agtttgcatc ccgtcagaag ataaagatac
     3061 ggatgaaaga catagcagat gagctgttac tgcagaggca tgacaggaaa attggagttt
     3121 ggaagcctgt ggagagtaag tggatatctt catcctgtga gattattgct ttccgtaaag
     3181 cattattgaa tccagtcatt gcaaggcaat ttcaacggtt tgtagccctg aaaggagatt
     3241 tattggaaaa tggagttctt ttttggcaag aagtacaaaa gtttaaggat ttgtgtcatt
     3301 cacattgtga ggagtccatc atccataaga agattacgac catcatcaac tgcttcatta
     3361 actcctgtat cccaccagct ctacagattg atattccagt tgagcaagcc cagaagatca
     3421 ttgaacacag gaaggagctg gggccatacg tgttccgaga ggcacagatg acaatttttg
     3481 gggttctgtt taagttttgg ccacagtttt gtgaatttag gaagaattta actgatgaga
     3541 aaatcatgag tgttttagaa agaaggcaag aatataagca gaaaaggaaa acatcagaca
     3601 tagaagagga caaagctgca aagtctggag tcaagcagta tgcaagtact acaggctctc
     3661 ttacaaaacc tactttaggc agcgagtcct tgctagtcct gcagtcctat ggccgacagc
     3721 ccacttggtg ctattcaaag tacatagaag ccttggaaca agagcgaatt cttctgaaaa
     3781 ttcaagaaga agtggaaaga aagatgttca caggtacatc gtctttcaca aacttgctta
     3841 agccttccac gggctccgct ctgtctctga agaagaatgt gtctcctcac agcatccaga
     3901 gatagcagca ttcctgtcca ggctcacatc ctccagcttc aagtaccagg atttctttag
     3961 gctaattgtt aactaacttg agaagctgaa tgcccacggt gtggatagtc cgatttactt
     4021 tagagtactt tagagtactt tagaggctag atgaattaaa gatttgtgcc tatcatactc
     4081 cttaaggaaa aagcatgtgt agtctttcag cagatatccc ttgcaggctc ggcatatctg
     4141 gttagcagat ctattcactg gatggttatg ggtgtgccta ttcctccgcc tccatttcag
     4201 ctgtgatgaa ctgtggaagc actggtcttt acacagcagc acccacagga cccacacggc
     4261 gagggttagc atctcaggtg cctcggatcc ctccatgcaa gccttccagc tattcagggg
     4321 gcactctaga gcctccatcg tcaccaggca cctcagtggt tttaactggg acctgcgcta
     4381 cagactactc ttgatgcaga ctgttagggt caaaagaaat ggtgctgaga aagggaggag
     4441 gcctggtgca catgggctcc acatgcggca aaggagaacc agacaacacg taaaagaaga
     4501 cctgagaggg acccttgtga cccacatcac taaagcgctc cgaggactac aactcagact
     4561 agaaactgtc ccacacagtc ccaagaggtc ttttcaaaga taaaactgtc atcccaaatt
     4621 ctccaggtag tttggaactt taaataggga atgtatcggc tgacatactt gtaaggtccc
     4681 ctttcctcta aagaagggac tttgcagagc agagacaagc tcctgagagt ccctccttca
     4741 gggcaaggat cttgctgtgc gtccaggctg ccctccatcc tcctgagtct ctgggattgc
     4801 cagacaaggt gtggcttgtc acgccttgct agatagaatg tccctgcact gtgccgcagc
     4861 accctatgca gtggccctgg aactcactgt ttgacaaagc cctgaaagag ctcagtgcct
     4921 caagggttcc gatccttctc cctcctccgc ttcagctgag gttttattga tttgtttgtt
     4981 ttcccgttgt tcaattttct gttctctcaa caggttaggt ataatttcca ataagttgtt
     5041 tttcccagtc gttaatattc attacagcaa atgagacccc actcctggtc acagtgttgg
     5101 gctgcttcct gaagagtgca agcactgtag aatattaacc aaagtaagat aaaataaaat
     5161 atatatcatc ttctta
//
