LOCUS       NM_001402015            2056 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus regulator of G-protein signaling 20 (Rgs20),
            transcript variant 2, mRNA.
ACCESSION   NM_001402015 XM_017593465
VERSION     NM_001402015.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Sun H, Calipari ES, Beveridge TJ, Jones SR and Chen R.
  TITLE     The brain gene expression profile of dopamine D2/D3 receptors and
            associated signaling proteins following amphetamine
            self-administration
  JOURNAL   Neuroscience 307, 253-261 (2015)
   PUBMED   26321241
REFERENCE   2  (bases 1 to 2056)
  AUTHORS   McAllister CE, Mi Z, Mure M, Li Q and Muma NA.
  TITLE     GPER1 stimulation alters posttranslational modification of RGSz1
            and induces desensitization of 5-HT1A receptor signaling in the rat
            hypothalamus
  JOURNAL   Neuroendocrinology 100 (2-3), 228-239 (2014)
   PUBMED   25402859
  REMARK    GeneRIF: Results demonstrate that RGSz1 isoforms with different
            posttranslational modifications are differentially distributed in
            subcellular organelles
REFERENCE   3  (bases 1 to 2056)
  AUTHORS   Chatterjee TK and Fisher RA.
  TITLE     Cytoplasmic, nuclear, and golgi localization of RGS proteins.
            Evidence for N-terminal and RGS domain sequences as intracellular
            targeting motifs
  JOURNAL   J Biol Chem 275 (31), 24013-24021 (2000)
   PUBMED   10791963
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000160.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001402015.2.
            
            On Mar 3, 2022 this sequence version replaced XM_017593465.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760396,
                              SAMEA5760433 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-276               JACYVU010000160.1  2492537-2492812
            277-591             JACYVU010000160.1  2543054-2543368
            592-743             JACYVU010000160.1  2607644-2607795
            744-827             JACYVU010000160.1  2613773-2613856
            828-1062            JACYVU010000160.1  2618622-2618856
            1063-2056           JACYVU010000160.1  2621425-2622418
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q12"
     gene            1..2056
                     /gene="Rgs20"
                     /note="regulator of G-protein signaling 20"
                     /db_xref="GeneID:362477"
                     /db_xref="RGD:1586146"
     exon            1..276
                     /gene="Rgs20"
                     /inference="alignment:Splign:2.1.0"
     CDS             109..1251
                     /gene="Rgs20"
                     /note="isoform 2 is encoded by transcript variant 2"
                     /codon_start=1
                     /product="regulator of G-protein signaling 20 isoform 2"
                     /protein_id="NP_001388944.1"
                     /db_xref="GeneID:362477"
                     /db_xref="RGD:1586146"
                     /translation="MPSLPQGNQGYLEEHLSGQAEQAQLLPLIRAEKDSNSSIPQDPE
                     NKGVSQAVTGVKLPDSPNAPTLLRHLSSLLSSHRRLFLCLLRRPPPAARLRPWDFPSQ
                     PSSWPTAWLSPVPRRLLFLLVASMALPGRPPRGRRLKLSSPSQELREEDACTGKSSPE
                     SPVESEQTEMRMRQMCSGSETQGSVPSQQQGVGGRGSNACCFCWCCCCSCSCLTVRNQ
                     EDQRPQRAAHELRTDIPACEESPMPTLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEF
                     SEENMLFWMACEELKREANKSTIEEKARIIYEDYISILSPKEVSLDSRVREVINRNMV
                     DPSQHIFDDAQLQIYTLMHRDSYPRFMNSTVYKDLLKSLAEKAVEA"
     exon            277..591
                     /gene="Rgs20"
                     /inference="alignment:Splign:2.1.0"
     exon            592..743
                     /gene="Rgs20"
                     /inference="alignment:Splign:2.1.0"
     exon            744..827
                     /gene="Rgs20"
                     /inference="alignment:Splign:2.1.0"
     exon            828..1062
                     /gene="Rgs20"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..2056
                     /gene="Rgs20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcagactca gacatgggcc agcattagcc agccaaagaa cagagacgat acctggatgt
       61 tggtaaaacc ggatgacaag actccggtag ggcatttgtt aggaaaacat gcccagcctt
      121 ccccaaggaa accaaggcta cctggaggag catctttccg ggcaggctga gcaggcacag
      181 ttgctgcccc tgatcagagc agagaaagat tccaattcca gtattcccca agacccagaa
      241 aataaagggg tctctcaggc tgtgactggt gtcaagctcc cagactcgcc caacgcgccc
      301 actctacttc gccacctttc tagcctgctc tccagccaca ggagattgtt cttgtgtctt
      361 ctgcggcgac cccctcccgc ggctcgcctg cgaccctggg actttccttc tcagccaagc
      421 tcctggccta cggcctggct ctctccagtg ccccgccgcc tcctgtttct acttgtggcc
      481 tcaatggcac tgccaggacg acctccgagg ggtcgtcgtc tgaagctgtc aagtccgagc
      541 caggagctca gagaagagga cgcctgtact gggaagagtt cgccggaatc tcctgtggaa
      601 tctgagcaga ccgaaatgcg gatgcggcag atgtgcagcg gaagtgagac gcagggctct
      661 gtcccaagcc agcagcaggg cgtgggcggc cgaggctcca atgcctgctg cttttgctgg
      721 tgctgctgct gcagctgttc ttgcctcacc gtcagaaacc aagaagacca gagaccccaa
      781 agagctgccc acgaactcag aacagacatt ccagcgtgtg aagaaagccc catgcccact
      841 ctggaagaag tctgtgcctg ggcccaatct tttgacaacc taatggtcac tccagctgga
      901 agaaatgcat tccgggaatt tcttcgaaca gaattcagtg aggaaaacat gctcttctgg
      961 atggcctgtg aggaactgaa aagggaagct aataaaagca ctattgagga gaaagcaagg
     1021 ataatatatg aagactacat ttctattctc tctccgaaag aggtcagcct ggactcccga
     1081 gtgcgagagg ttatcaacag aaacatggtg gatccatctc aacacatctt tgatgacgct
     1141 caactgcaga tctacaccct aatgcacaga gactcctatc cccgcttcat gaactccaca
     1201 gtctataagg atttacttaa gtccttagct gagaaagcag ttgaagcata ggtggttttg
     1261 aatatattta ttattaacaa aacaagaaaa taactcatgg attccgtcta gcacagggga
     1321 tttagagata ggatgtcttg tgctacagtg attctgactg ttgtaataac agattcttcc
     1381 tccacggaaa gttctcgatt cacaatggaa attgcagcca cctatagcga tacttatcag
     1441 acaagagggc ggtgggcatg actgccttag atagtgtgct cacactcaca ataacagtag
     1501 catgttctca ggggcagggc atgcactagc ctctgttctg cctgaagcat agatatacaa
     1561 ggaacaaatg gtaacacttt gttttgcatg agttcaatac tatattgctc tccaaagaag
     1621 tggcattcaa atccttctca actaaccctt ccctcagtct gaatacttta cttggcacca
     1681 tgccaggtct gagagtcaca tctcacaaag atgtgaccat tccttgtaaa aatggtggaa
     1741 acctgttctc tctctctctc tctctctctc tctctctctc tctctctctc tctctttctc
     1801 tctctctgca tgcctgtgtg tgttcaagtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     1861 tgtgtgtgtg tgtgatctgt tatggttggt agaacacatc atgctctagg tgggtcactc
     1921 tcagaggttt ggtaaatgaa gcaacattta aaatgaaaag atgactgtat tgtcagaacg
     1981 tgaagaatga actttgaagt tcatagtttg tcatgttcac aaatcctcaa ataaacaatt
     2041 ttaattttta ttgaaa
//
