LOCUS       NM_001047084            1993 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus regulator of G-protein signaling 18 (Rgs18),
            mRNA.
ACCESSION   NM_001047084 XM_001068803 XM_222692
VERSION     NM_001047084.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1993)
  AUTHORS   Kveberg,L., Ryan,J.C., Rolstad,B. and Inngjerdingen,M.
  TITLE     Expression of regulator of G protein signalling proteins in natural
            killer cells, and their modulation by Ly49A and Ly49D
  JOURNAL   Immunology 115 (3), 358-365 (2005)
   PUBMED   15946253
REFERENCE   2  (bases 1 to 1993)
  AUTHORS   Nagata,Y., Oda,M., Nakata,H., Shozaki,Y., Kozasa,T. and Todokoro,K.
  TITLE     A novel regulator of G-protein signaling bearing GAP activity for
            Galphai and Galphaq in megakaryocytes
  JOURNAL   Blood 97 (10), 3051-3060 (2001)
   PUBMED   11342430
REFERENCE   3  (bases 1 to 1993)
  AUTHORS   Park,I.K., Klug,C.A., Li,K., Jerabek,L., Li,L., Nanamori,M.,
            Neubig,R.R., Hood,L., Weissman,I.L. and Clarke,M.F.
  TITLE     Molecular cloning and characterization of a novel regulator of
            G-protein signaling from mouse hematopoietic stem cells
  JOURNAL   J Biol Chem 276 (2), 915-923 (2001)
   PUBMED   11042171
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Oct 14, 2022 this sequence version replaced NM_001047084.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.42305.1,
                                           SRR26360194.1940308.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-302               JAXUCZ010000013.1  59066041-59066342   c
            303-404             JAXUCZ010000013.1  59065501-59065602   c
            405-466             JAXUCZ010000013.1  59064757-59064818   c
            467-633             JAXUCZ010000013.1  59046613-59046779   c
            634-1993            JAXUCZ010000013.1  59043431-59044790   c
FEATURES             Location/Qualifiers
     source          1..1993
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q21"
     gene            1..1993
                     /gene="Rgs18"
                     /note="regulator of G-protein signaling 18"
                     /db_xref="GeneID:289076"
                     /db_xref="RGD:1306522"
     exon            1..302
                     /gene="Rgs18"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..891
                     /gene="Rgs18"
                     /codon_start=1
                     /product="regulator of G-protein signaling 18"
                     /protein_id="NP_001040549.2"
                     /db_xref="GeneID:289076"
                     /db_xref="RGD:1306522"
                     /translation="MEMSLVFFSHLNMCESKEKTFFKLMHGSGKEETNIEAKIRAKEK
                     RNRLSLLLQRPDFHGETHTSRSALLAKETRVSSEEALKWAESFDKLLSHRDGVDAFTR
                     FLKTEFSEENIEFWVACEDFKKCTEPQQLILKAKSIYEKFIKNDAPKEVNLDFHTKEV
                     ITKSIAQPTLHSFDAAQSRVCQLMEHDSYKRFLKSEIYLHLIEGRPQRPTNLRRRSRS
                     FTYNEFQDVKSDVAIWL"
     exon            303..404
                     /gene="Rgs18"
                     /inference="alignment:Splign:2.1.0"
     exon            405..466
                     /gene="Rgs18"
                     /inference="alignment:Splign:2.1.0"
     exon            467..633
                     /gene="Rgs18"
                     /inference="alignment:Splign:2.1.0"
     exon            634..1993
                     /gene="Rgs18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agacttgcag aggcagaaac gcagctcttc actttctttc ctggtctttt ctcccttttg
       61 taagctctgt ggaaagattc aggatagcgc tttattcagc atgttttcca gtgaaatagc
      121 attcatccat gggaaagaga aggactgaga aaatccgaca tctcttgatc actgggacag
      181 aatatggaaa tgtcactggt tttcttctct cacttaaata tgtgtgaatc caaagagaaa
      241 acttttttca aactaatgca cgggtcagga aaagaagaaa caaacatcga ggccaaaatc
      301 agagctaaag aaaaaaggaa tagactaagt cttctcctac agaggcctga cttccatgga
      361 gagactcaca ccagtagatc tgccctgttg gccaaagaaa caagagtctc ctctgaagaa
      421 gcactgaaat gggctgaatc atttgacaaa ctgctttctc atagagatgg agtagatgca
      481 tttaccagat ttcttaaaac tgaattcagt gaagaaaaca ttgaattttg ggttgcctgt
      541 gaagacttca agaaatgcac ggaacctcaa caactcatcc taaaagcaaa atcaatatat
      601 gagaaattca ttaaaaatga tgcccctaaa gaggttaacc ttgattttca tactaaagaa
      661 gtaattacta agagcatcgc ccagcccact ctccacagtt ttgatgcagc acaaagcaga
      721 gtgtgtcagc tcatggaaca cgacagttat aaacgctttc tgaaatccga gatctactta
      781 catttgatag agggaagacc tcagagacca acaaatctta ggaggcgatc gcgatccttt
      841 acctacaatg agttccaaga cgtaaaatca gatgttgcca tttggttatg agtaaaagtc
      901 attttttttc ttttgataat acatgtgtac atctgcttct aaaaatatag catgtgtata
      961 gtacgaaatg atttcacttt taaaatacac caggcagaag tattttaaat gtaagaacct
     1021 ttatattata ctaaaataat tcatcgtcta ttttcccata tatttgatga aaatcatatc
     1081 ttctatatta ttcataataa aaatctttat ttctacaata gatgtcagta agaagaagct
     1141 ttgtaaattg ttaaagtaaa atgaaaactc tgcagtaatg tcacgtctag tttggattat
     1201 atttctaagc aaaaacaatg tatttagata agtatataaa tacagatgat atttgacatc
     1261 atgaaggatt ggggcataca gagacgaccc atctctttta taacagggaa ggatggatat
     1321 ttattgttgc atactcattc tgactccaga ttagctgttg gtcacttcca tttttaagca
     1381 agccaaaaga tgtgttataa agatgtattt ctctctacat attaaatggg actgtcttaa
     1441 cccaggtatg tatctgagac ttcactctgc agtcagatgt accctgagga acaattcccc
     1501 attagagaga gcaacactcc tgttcacacc cgcatgctca tgctaatgat ctccaatatc
     1561 tgcagagtgg gccaccttct atctcaataa gtgactgagc cacattaaaa taacaccaat
     1621 cagtgcttga atgatgatga cgatggcata cttccacaca agcatttatg tctcacattt
     1681 ggaattttaa agttggtgta gaagtccaaa cagagagata gtgaaaagta aaatccacaa
     1741 atttgacaac attgacatca tccaaccctg ttctctcatt acgttctttc aattcttgcc
     1801 taatactata ttatacagta aggttatact aataaataaa ctctatttta caaaaatgtt
     1861 taattgcaat gtgttatgca gtctataaat gtttgtatta aagatgaaat gctttcaaat
     1921 taataaatgc tcttgtcttc atagaagtgt ataacaaatt taacatctat cataataaag
     1981 tgttaaaact taa
//
