LOCUS       NM_001107459            2493 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus regulator of G-protein signaling 17 (Rgs17),
            mRNA.
ACCESSION   NM_001107459 XM_001059287 XM_217837
VERSION     NM_001107459.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2493)
  AUTHORS   Dhukhwa,A., Al Aameri,R.F.H., Sheth,S., Mukherjea,D., Rybak,L. and
            Ramkumar,V.
  TITLE     Regulator of G protein signaling 17 represents a novel target for
            treating cisplatin induced hearing loss
  JOURNAL   Sci Rep 11 (1), 8116 (2021)
   PUBMED   33854102
  REMARK    GeneRIF: Regulator of G protein signaling 17 represents a novel
            target for treating cisplatin induced hearing loss.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2493)
  AUTHORS   Sun,H., Calipari,E.S., Beveridge,T.J., Jones,S.R. and Chen,R.
  TITLE     The brain gene expression profile of dopamine D2/D3 receptors and
            associated signaling proteins following amphetamine
            self-administration
  JOURNAL   Neuroscience 307, 253-261 (2015)
   PUBMED   26321241
REFERENCE   3  (bases 1 to 2493)
  AUTHORS   Sokolov,E., Iannitti,D.A., Schrum,L.W. and McKillop,I.H.
  TITLE     Altered expression and function of regulator of G-protein
            signaling-17 (RGS17) in hepatocellular carcinoma
  JOURNAL   Cell Signal 23 (10), 1603-1610 (2011)
   PUBMED   21620966
  REMARK    GeneRIF: RGS17 is differentially expressed in hepatocellular
            carcinoma cells and plays a central role in regulating transformed
            hepatocyte tumorgenicity.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474052.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_217837.4, XM_001059287.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132261, SAMD00132262
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2493
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q11"
     gene            1..2493
                     /gene="Rgs17"
                     /note="regulator of G-protein signaling 17"
                     /db_xref="GeneID:308118"
                     /db_xref="RGD:1305515"
     exon            1..158
                     /gene="Rgs17"
                     /inference="alignment:Splign:2.1.0"
     exon            159..231
                     /gene="Rgs17"
                     /inference="alignment:Splign:2.1.0"
     exon            232..375
                     /gene="Rgs17"
                     /inference="alignment:Splign:2.1.0"
     CDS             257..889
                     /gene="Rgs17"
                     /codon_start=1
                     /product="regulator of G-protein signaling 17"
                     /protein_id="NP_001100929.1"
                     /db_xref="GeneID:308118"
                     /db_xref="RGD:1305515"
                     /translation="MRKRQQSQNEGTQAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVR
                     NEERGDSSGRPPHTTKMESIQVLEECQNPTADEVLSWSQNFDKMMKAPAGRNLFREFL
                     RTEYSEENLLFWLACEDLKKEQNKKAVEEKARMIYEDYISILSPKEVSLDSRVREVIN
                     RNLLEPSPHMYEDAQLQIYTLMHRDSFPRFLNSQIYKAFVESTASSTSES"
     exon            376..465
                     /gene="Rgs17"
                     /inference="alignment:Splign:2.1.0"
     exon            466..700
                     /gene="Rgs17"
                     /inference="alignment:Splign:2.1.0"
     exon            701..2493
                     /gene="Rgs17"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctcggctc tatcctggcc tctctccctc tctccgtcgc cgggtgctga agttgggcgg
       61 atggcaagga gcccgctccg ctagaggacg gaacagccca gccttgagca cactcggact
      121 cggacccggg gacggtcgcc cacatcccag gccacctggt ttattatata tactgcctaa
      181 ttcccatcaa gatatgtgat tcttcccaac aaattattgc taagatggca gccagtcgga
      241 ttctgaagca gctgacatga gaaaacggca gcagtcacaa aatgaaggca cgcaggctgt
      301 gtctcaagcg cccggaaacc aaaggcccaa caacacctgt tgcttctgct ggtgctgctg
      361 ctgcagctgc tcctgcctca ctgtcaggaa tgaagaaaga ggagactctt cggggagacc
      421 cccacacacc accaaaatgg agagcatcca ggtcctagag gaatgccaaa accccactgc
      481 agatgaagtc ttgtcctggt ctcagaattt tgacaagatg atgaaggctc ctgcaggaag
      541 aaaccttttc cgagagttcc tccgaacaga atacagcgag gagaacctac tcttctggct
      601 ggcctgtgaa gacttaaaga aggagcagaa caagaaagct gttgaagaaa aggccaggat
      661 gatatacgag gattacattt ctatactgtc accgaaagag gtcagcctcg attctcgagt
      721 tagagaggtg atcaacagga atctgctgga gcccagccct cacatgtacg aagatgccca
      781 gcttcagatc tacaccctaa tgcacagaga ttctttccca agattcttga actcgcagat
      841 ctacaaagcc tttgtcgaaa gtactgccag ctccacttct gaatcttaat tttcatttga
      901 aaggccaaaa aaaaaatcat ttcagagggc tgggatggga aataaaagta attaaataac
      961 atcagaaatc gagttcctga aaaaaacgac aggttggctg ctgggaaaag acaactggga
     1021 aagtcgtttg tctctatttt tatcaaggtt atccatgatt ctgttagggg gtaaaaagcc
     1081 tgtgtaagaa aatgagttgc caaattgagt ttgtttgatt caacacttgc tctccttgca
     1141 agcgaactat gttcctagtc ctctgaacaa tcccctagtg catctctaga ggccgcatgt
     1201 gcaaagtaaa accgcttcgt ctgcccttta cttgtgccat taagtcagta gcataccttg
     1261 tatctgtatt taaggacttc tgtgcaatat ggtctcttag aaacaattgc caacaaattg
     1321 gccgtggttt gcatttttta agcataatct gatacacaca aaggctattt taaacatgta
     1381 acagtgatat ttaaccacgc tacatactat gtttagtaca tggactctga agccaatttt
     1441 tctgtacatg ttaaaaaaaa aagtgaccat tgaaggacct tattgtgtga gacctctggt
     1501 tgttcactgc ccacattctg acatttttgt tacagaagag tttgctatat atatatttta
     1561 agagaaagaa aagagagaaa aagaaagaaa acaaaaatag ttaacaatga taagaaaaat
     1621 tttaaaaagc acaaaacaat ctgcagatat cctgtctcgt tgaaaattcc aagaaggata
     1681 ctatttttag gtctaaaaga aagaaaagag tctatgtata tatcagatgt ccaatagtgt
     1741 aattaattta tcaaagaaag gctcttcagt tctaaaagca ttgcataaac ctatgactgt
     1801 cagcaggtaa acaataataa gttcagtaac ccagtttggg aatagaacgg gaagggtaat
     1861 aaagaaatgc ctacatgtag cactgtaaaa gtcacctttg aggagtcgcc tctgtgtggc
     1921 gcgctcacct tgaacgtgta attcagtgaa aagcttgagt ttttcctaac caacatttta
     1981 caagggatta tagagaagaa agccttcgat gtcagacctt aactgttttc accgtagtct
     2041 ctcaagaaag acttattttt aacattgtta aaatcaaact accaaccctc gtccgtaact
     2101 agaaggcagt gcagtgctca atccttttag ctgccaatat tattttttat aattacatta
     2161 actctttaca cggatactca catgaccatg gtatgcattt ctgaccttca gaacagtatc
     2221 gtcttgtgca caaaaccaaa attacaatca atgtcatatt tatatcaagg tcctaccttt
     2281 caatatcaaa atcccctgga gactattttt ttaatcttaa actcaatgaa tatatgttga
     2341 gtaaccttta aaaaatgaaa gatttaaaaa gatttataac cactgagaat actggcctta
     2401 tattaaggat gatattaaaa ttaaaggttt tgtttgtcat ttttaactac ctctcagttt
     2461 ttaatttatt aaacatattt ttttaagatg caa
//
