LOCUS       NM_019338               2157 bp    mRNA    linear   ROD 04-MAR-2025
DEFINITION  Rattus norvegicus regulator of G-protein signaling 11 (Rgs11),
            mRNA.
ACCESSION   NM_019338
VERSION     NM_019338.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2157)
  AUTHORS   Orlandi,C., Posokhova,E., Masuho,I., Ray,T.A., Hasan,N., Gregg,R.G.
            and Martemyanov,K.A.
  TITLE     GPR158/179 regulate G protein signaling by controlling localization
            and activity of the RGS7 complexes
  JOURNAL   J Cell Biol 197 (6), 711-719 (2012)
   PUBMED   22689652
REFERENCE   2  (bases 1 to 2157)
  AUTHORS   Lyssand,J.S., DeFino,M.C., Tang,X.B., Hertz,A.L., Feller,D.B.,
            Wacker,J.L., Adams,M.E. and Hague,C.
  TITLE     Blood pressure is regulated by an alpha1D-adrenergic
            receptor/dystrophin signalosome
  JOURNAL   J Biol Chem 283 (27), 18792-18800 (2008)
   PUBMED   18468998
REFERENCE   3  (bases 1 to 2157)
  AUTHORS   Lopez-Fando,A., Rodriguez-Munoz,M., Sanchez-Blazquez,P. and
            Garzon,J.
  TITLE     Expression of neural RGS-R7 and Gbeta5 Proteins in Response to
            Acute and Chronic Morphine
  JOURNAL   Neuropsychopharmacology 30 (1), 99-110 (2005)
   PUBMED   15199376
REFERENCE   4  (bases 1 to 2157)
  AUTHORS   Zhou,J.Y., Toth,P.T. and Miller,R.J.
  TITLE     Direct interactions between the heterotrimeric G protein subunit G
            beta 5 and the G protein gamma subunit-like domain-containing
            regulator of G protein signaling 11: gain of function of cyan
            fluorescent protein-tagged G gamma 3
  JOURNAL   J Pharmacol Exp Ther 305 (2), 460-466 (2003)
   PUBMED   12606627
REFERENCE   5  (bases 1 to 2157)
  AUTHORS   Gold,S.J., Ni,Y.G., Dohlman,H.G. and Nestler,E.J.
  TITLE     Regulators of G-protein signaling (RGS) proteins: region-specific
            expression of nine subtypes in rat brain
  JOURNAL   J Neurosci 17 (20), 8024-8037 (1997)
   PUBMED   9315921
REFERENCE   6  (bases 1 to 2157)
  AUTHORS   Koelle,M.R. and Horvitz,H.R.
  TITLE     EGL-10 regulates G protein signaling in the C. elegans nervous
            system and shares a conserved domain with many mammalian proteins
  JOURNAL   Cell 84 (1), 115-125 (1996)
   PUBMED   8548815
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Jan 14, 2022 this sequence version replaced NM_019338.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN13663602,
                              SAMN16418986 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-78                JAXUCZ010000010.1  15727279-15727356
            79-175              JAXUCZ010000010.1  15727612-15727708
            176-226             JAXUCZ010000010.1  15727778-15727828
            227-333             JAXUCZ010000010.1  15727900-15728006
            334-385             JAXUCZ010000010.1  15728680-15728731
            386-444             JAXUCZ010000010.1  15728825-15728883
            445-521             JAXUCZ010000010.1  15729257-15729333
            522-603             JAXUCZ010000010.1  15729515-15729596
            604-672             JAXUCZ010000010.1  15730120-15730188
            673-696             JAXUCZ010000010.1  15731682-15731705
            697-758             JAXUCZ010000010.1  15731780-15731841
            759-872             JAXUCZ010000010.1  15731936-15732049
            873-988             JAXUCZ010000010.1  15732146-15732261
            989-1076            JAXUCZ010000010.1  15732388-15732475
            1077-1215           JAXUCZ010000010.1  15732553-15732691
            1216-1298           JAXUCZ010000010.1  15734512-15734594
            1299-2157           JAXUCZ010000010.1  15734678-15735536
FEATURES             Location/Qualifiers
     source          1..2157
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..2157
                     /gene="Rgs11"
                     /note="regulator of G-protein signaling 11"
                     /db_xref="GeneID:54291"
                     /db_xref="RGD:3563"
     exon            1..78
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..1413
                     /gene="Rgs11"
                     /codon_start=1
                     /product="regulator of G-protein signaling 11"
                     /protein_id="NP_062211.1"
                     /db_xref="GeneID:54291"
                     /db_xref="RGD:3563"
                     /translation="MATVRGCTPHRGCSRMQRPHLSKMERVVVSMQDPDQGVKMRSQR
                     LLITVIPHAVAGRDIVEWLVQKFCISEEEALHLGTLLTQHGYIYPLRESRDLTLRPDE
                     TPYRFQTPYFWTSTLWPAAELDYAIYLAKKNIQKQGALVDYEKEHYTLLHKKINHAWD
                     LVLMQAREQLRAAKQRRKGDRLVISCQEQTYWLVNKPPPGAPNVLEQGPERGSDNPSQ
                     VQMSSDFYKCEIECFRKALSRNRVKSSVCLEAYLKFSSQHGPHDPILSGCLPSNPWIT
                     DDVTYWVMNAPNVAAPTKLRVERWSFSFRELLDDPVGRIHFMDFLQKEFSAENLSFWE
                     ACEELRFGGQAQVPTLVDSVYQQFLAPGAARWINIDSRTMEWTLEGLRQPHRYVLDAA
                     QLHIYMLMKKDSYPRFLKSDIYRGLLEEAVIPLETKRWPFPFLRKPLHSSPSPALQST
                     SGEPAATSSPAGGNEED"
     exon            79..175
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            176..226
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            227..333
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            334..385
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            386..444
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            445..521
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            522..603
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            604..672
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            673..696
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            697..758
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            759..872
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            873..988
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1076
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1215
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1298
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
     exon            1299..2157
                     /gene="Rgs11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggtccgcca tggccacggt tagaggctgc acaccccatc gcgggtgctc ccgaatgcag
       61 agaccacatc tcagcaagat ggaacgggtg gtcgtgagta tgcaggaccc tgaccagggc
      121 gtgaagatgc ggagccagcg ccttctgatc accgtcattc cccacgcggt ggcgggcaga
      181 gacatcgtgg aatggctggt ccagaagttc tgcatctcgg aggaggaagc cctgcacctg
      241 ggcacactcc tgacacagca cggctacatc tacccactgc gtgagtcccg agacctgacg
      301 ctcaggccgg acgagacccc ctacaggttc cagacaccct acttttggac aagcactctg
      361 tggccagctg ctgaactgga ctatgccatc tacctggcta agaagaacat ccaaaaacaa
      421 ggggccttgg tggactatga gaaggaacat tacaccctgc tgcacaagaa gatcaaccat
      481 gcgtgggatc tagtattgat gcaggctcga gagcagctgc gggctgctaa gcagcgcagg
      541 aagggagaca ggctggtcat ttcgtgtcag gagcagacat actggctggt gaacaaaccc
      601 cctcctgggg cacctaatgt tctggagcag ggtcctgaga ggggttctga taaccccagt
      661 caagtgcaga tgagctcgga tttctataag tgtgagatcg agtgcttcag gaaggcgctg
      721 agcaggaacc gggtgaagtc ctctgtctgc ctcgaggcgt acctgaagtt cagcagccag
      781 catgggccgc acgatcccat cctgtcaggg tgcctgccca gcaacccctg gatcacagac
      841 gatgtcacct actgggtcat gaatgcgccc aatgtggctg ccccgacaaa gctccgcgtc
      901 gagcgatgga gcttcagctt ccgggagctc ctggatgacc ccgtggggcg tatccacttc
      961 atggactttc tgcagaagga attcagtgcg gaaaacctca gcttctggga ggcgtgtgag
     1021 gagctgcgct ttggcggaca ggcccaggtc cccaccctgg tggactctgt ttaccagcag
     1081 ttcctggccc ctggagctgc ccgctggatc aacattgaca gcagaacaat ggagtggacc
     1141 ctggaggggc tgcgccagcc acaccgctat gtcctagatg cagcacaact gcacatctac
     1201 atgctcatga agaaggactc ctatccaagg ttcctaaagt ctgatatcta cagagggctg
     1261 ctggaggaag ctgtgattcc gctggagacc aagcgctggc cattcccatt cttgcggaag
     1321 cctctgcact caagtcccag ccctgctctc cagtcgacct ctggggagcc tgcagctacc
     1381 agctcccctg caggtggcaa tgaggaggac taagtggctc ttgctgcaca tgtcacctta
     1441 tcatcacctg cctgacaccc tgtggggtca tgttctcctc actgagatac tcccagcact
     1501 ggtgtctccc tgtagagggc ccagccttgc tacgaggccc tttagcctcc actaagtaag
     1561 ccctctcctt cccagaaggg actggcccag ctgattccta gggcaagatt tcattggctg
     1621 atccttgcca ggacagaact tgttctagga agtaaaatca aggtcctcag ttcctggtat
     1681 tctgtagtct tcaattcagg actaggaggc catctcaacc ttagaaagtt gtcagtgaca
     1741 catgcggaag tgttgtttct ggccatgcca tcctattcag gaggactcct cccctgtgta
     1801 acctactcct taggctaaac ccagtgactt ctcagtagac tatgtgtgca gatgccgttt
     1861 tactgccata catggcatct cgtccacctg ccttctgacc agatgtgtag aaaggccact
     1921 ccacagtggt gtcctgactg tagggctccc agatctctta gcaagtcttt gtcaagctgg
     1981 cagccgtagc atccaggctt cctgtctagg ttgtcctgtg ccaccagcat tgccaccccc
     2041 accccagagg tagaaataga gacggcacct ccttctgcta tgcagctccc ggcagggcta
     2101 ttctctagtc tccctcacaa cccattccta cagaaatgaa agtttcaggc cctggca
//
