LOCUS       NM_001013136            1457 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus regulatory factor X-associated ankyrin-containing
            protein (Rfxank), mRNA.
ACCESSION   NM_001013136 XM_224739
VERSION     NM_001013136.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1457)
  AUTHORS   McKinsey,T.A., Kuwahara,K., Bezprozvannaya,S. and Olson,E.N.
  TITLE     Class II histone deacetylases confer signal responsiveness to the
            ankyrin-repeat proteins ANKRA2 and RFXANK
  JOURNAL   Mol Biol Cell 17 (1), 438-447 (2006)
   PUBMED   16236793
REFERENCE   2  (bases 1 to 1457)
  AUTHORS   Wiszniewski,W., Fondaneche,M.C., Louise-Plence,P.,
            Prochnicka-Chalufour,A., Selz,F., Picard,C., Le Deist,F.,
            Eliaou,J.F., Fischer,A. and Lisowska-Grospierre,B.
  TITLE     Novel mutations in the RFXANK gene: RFX complex containing
            in-vitro-generated RFXANK mutant binds the promoter without
            transactivating MHC II
  JOURNAL   Immunogenetics 54 (11), 747-755 (2003)
   PUBMED   12618906
REFERENCE   3  (bases 1 to 1457)
  AUTHORS   Lin,J.H., Makris,A., McMahon,C., Bear,S.E., Patriotis,C.,
            Prasad,V.R., Brent,R., Golemis,E.A. and Tsichlis,P.N.
  TITLE     The ankyrin repeat-containing adaptor protein Tvl-1 is a novel
            substrate and regulator of Raf-1
  JOURNAL   J Biol Chem 274 (21), 14706-14715 (1999)
   PUBMED   10329666
REFERENCE   4  (bases 1 to 1457)
  AUTHORS   Masternak,K., Barras,E., Zufferey,M., Conrad,B., Corthals,G.,
            Aebersold,R., Sanchez,J.C., Hochstrasser,D.F., Mach,B. and Reith,W.
  TITLE     A gene encoding a novel RFX-associated transactivator is mutated in
            the majority of MHC class II deficiency patients
  JOURNAL   Nat Genet 20 (3), 273-277 (1998)
   PUBMED   9806546
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087111.1.
            
            [WARNING] On Mar 21, 2025 this sequence was replaced by
            NM_001013136.2.
            
            On Apr 20, 2005 this sequence version replaced XM_224739.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087111.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132277
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1457
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..1457
                     /gene="Rfxank"
                     /note="regulatory factor X-associated ankyrin-containing
                     protein"
                     /db_xref="GeneID:306353"
                     /db_xref="RGD:1311390"
     exon            1..367
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
     exon            368..562
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
     CDS             376..1230
                     /gene="Rfxank"
                     /codon_start=1
                     /product="DNA-binding protein RFXANK"
                     /protein_id="NP_001013154.1"
                     /db_xref="GeneID:306353"
                     /db_xref="RGD:1311390"
                     /translation="MEPTQVAENLIPNQQSLAPDLEDPEDRRDESPDSSDTVVLSLFP
                     CTPDAVNPEADASASSLQVPAASVWTPLAQAQTPGEQALPLLAGSFLKHSTTLTNRQR
                     GNEVSALPATLDSLSIHQLAAQGELSQLKDHLRKGDNLVNKPDERGFTPLIWASAFGE
                     IETVRFLLDWGADPHILAKERESALSLASMGGYTDIVRLLLDRDVDINIYDWNGGTPL
                     LYAVRGNHVKCVEALLARGADLTTEADSGYTPMDLAVALGYRKVQQVMESHILKLFQG
                     TLGPADPE"
     exon            563..718
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
     exon            719..784
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
     exon            785..885
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
     exon            886..1011
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
     exon            1012..1078
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
     exon            1079..1159
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1362
                     /gene="Rfxank"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctccttca gccctttacg aaggatagcg cgcatgcgcc tctgtactca gaggcctcag
       61 cggaagccac gctcctccct ccattcttaa agggctagaa gccgattcgg gtttttattt
      121 tttatttttt ggtacttttg caggacaggg gtgcgcaggc gcagtggagg agttctcctg
      181 taggaatagt cctggcgtat taagttgctg ctctatgtcc cagcagaaga agctagagga
      241 ctgggcgtcc ggtcaccaac ttgctcctca cgagatctac tggactagaa aagtttgtga
      301 acagagcttc ccgagttttg ggagagccag gctggcagcg taagggaacg gaggaggctg
      361 gagggagctt cctcgatgga gcccactcag gttgcagaga acctcatccc aaaccagcag
      421 tcccttgctc ctgacctaga ggatcctgag gaccgcagag atgaatcccc agatagctct
      481 gacactgtcg tcctcagtct gttcccctgc accccagacg ctgtgaatcc tgaggcagat
      541 gccagtgcat cctcactaca ggttcctgca gcatctgtct ggacaccctt ggcacaagcc
      601 caaacaccag gggaacaagc ccttcctctc ctcgcaggaa gtttcttgaa gcactccaca
      661 accctcacaa accggcaacg tgggaatgag gtctcagctc tgccagccac cctggactcc
      721 ctgtctatcc accagcttgc agcccagggg gagctgagtc aactgaagga tcacctgcga
      781 aagggtgaca acctggtcaa caagccggat gaacgtggct tcacccccct catctgggcc
      841 tcagcctttg gagaaattga gacagtacgc ttcctgctag actggggtgc tgacccccac
      901 atcctggcca aggagcggga aagcgctctg tcgcttgcca gtatgggtgg ttacacggac
      961 atcgtgaggt tgctgcttga ccgtgatgtg gacatcaaca tctatgactg gaatgggggg
     1021 acaccactgc tctacgctgt gcgtgggaac catgtgaagt gtgtggaggc cttactcgcc
     1081 cgaggtgctg acctcaccac agaggccgac tctggctaca ccccaatgga cctcgccgtg
     1141 gccctaggat accgcaaagt gcaacaggtg atggagagcc acatcctcaa actgttccag
     1201 ggtaccctgg ggcctgcgga cccggagtga agacagcctg ttgggaaccc aggcactcag
     1261 ggacaaacca gtcagcccac aactggcttg gaaggcagct cctggacagt ggtgggaaga
     1321 gccctcccca acaggaacca ataaatctgt gcagaacttg aaaaaaaaaa aaaaaaaaaa
     1381 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1441 aaaaaaaaaa aaaaaaa
//
