LOCUS       NM_001105944            4156 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus regulatory factor X1 (Rfx1), mRNA.
ACCESSION   NM_001105944 XM_001068588 XM_222456
VERSION     NM_001105944.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4156)
  AUTHORS   Ma,K., Zheng,S. and Zuo,Z.
  TITLE     The transcription factor regulatory factor X1 increases the
            expression of neuronal glutamate transporter type 3
  JOURNAL   J Biol Chem 281 (30), 21250-21255 (2006)
   PUBMED   16723357
  REMARK    GeneRIF: RFX1 enhances the activity of EAAT3 promoter to increase
            the expression of EAAT3 proteins
REFERENCE   2  (bases 1 to 4156)
  AUTHORS   Safrany,G. and Perry,R.P.
  TITLE     Transcription factor RFX1 helps control the promoter of the mouse
            ribosomal protein-encoding gene rpL30 by binding to its alpha
            element
  JOURNAL   Gene 132 (2), 279-283 (1993)
   PUBMED   8224874
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473972.1.
            
            [WARNING] On Oct 17, 2024 this sequence was replaced by
            NM_001105944.2.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_222456.4, XM_001068588.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4156
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q11"
     gene            1..4156
                     /gene="Rfx1"
                     /note="regulatory factor X1"
                     /db_xref="GeneID:288906"
                     /db_xref="RGD:1306574"
     exon            1..184
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            185..523
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     CDS             226..3120
                     /gene="Rfx1"
                     /note="regulatory factor X, 1 (influences HLA class II
                     expression)"
                     /codon_start=1
                     /product="MHC class II regulatory factor RFX1"
                     /protein_id="NP_001099414.1"
                     /db_xref="GeneID:288906"
                     /db_xref="RGD:1306574"
                     /translation="MATQSYVTELQAAPQASQPPQAPPQALPQPPPPAAPQPPAAATP
                     QPQYVTELQSPQPQTQPPGSQKQYVAELPAAPAPSQPATPAPSPVAQQYIVVTVSEGA
                     MRASETVSEASPSSTASQTGVPTQVVQQVQGTQQRLLVQASVQAKPGHVSPLQLTNIQ
                     VPQQALPTQHLVVQSPAPGSKGGQVSLTVHSTQQVHSAPERSPVQANNSTSKTAGTPA
                     GTVQQLQVHSVQQSVPVTQERSVVQATPQTKAGPVQQLTVQGLQPVHVAQEVQQLPQV
                     PVPHVYSSQVQYVEGGDASYTASAIRSSTYQYPETPIYTQTAGTSYYEASGTAAQVST
                     PATSQTVASSGSVPMYVSGSPIVASSSSSEAGASNSSVGAGGNGGGGSGGGGGGSSGG
                     GSGAGTYVIQGGYMLGNASQSYSHTTRASPATVQWLLDNYETAEGVSLPRSTLYCHYL
                     LHCQEQKLEPVNAASFGKLIRSVFMGLRTRRLGTRGNSKYHYYGLRIKASSPLLRLME
                     DQQHMAMRGQPFSQKQRLKPIQKMEGVANGVAVGQQSTGLSDISAQVQQYQQFLDASR
                     SLPDFAELDLQGKVLPEGVGPGDIKAFQVLYREHCEAIVDVMVNLQFTLVETLWKTFW
                     RYNLSQPNEAPPLAVHDEAEKRLPRASLVLLSKFQPVLQWTKHCDNVLYQGLVEILIP
                     DVLRPIPSALTQAIRNFAKSLESWLTHAMVNIPEEMLRVKVAAAGAFAQTLRRYTSLN
                     HLAQAARAVLQNTAQINQMLSDLNRVDFANVQEQASWVCRCEDRVVQRLEQDFKVTLQ
                     QQNSLEQWAAWLDGVVSQVLKPYQGSSGFPKAAKLFLLKWSFYSSMVIRDLTLRSAAS
                     FGSFHLIRLLYDEYMYYLIEHRVAQAKGETPIAVMGEFANLATSLNPLDPDKDEEEEE
                     EEESEDELPQDISLAAGSESPALGPETLEPPAKLARTDTRGLFVQALPSS"
     exon            524..633
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            634..717
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            718..825
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            826..939
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            940..1032
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1127
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1497
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1498..1679
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1680..1799
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1800..1912
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            1913..2031
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            2032..2141
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2293
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            2294..2391
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            2392..2541
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            2542..2750
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            2751..2904
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            2905..2950
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
     exon            2951..4156
                     /gene="Rfx1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 catagccacg gtagtcgtgg cgaccaagca acccagcaac gccagtcaac aacaacaact
       61 gcggccgccc cccaccccca cgcccccggc ccggcctggg gaccccggcg tgctcggtcc
      121 cctctgcaca gcgcccacgc acctccttaa agccttccgc ggacacaagt gcggagaagc
      181 cgaggaagag gaaaaccgcc ttatttatta tcattcactg ttggcatggc aacacagtcc
      241 tatgttactg agctacaggc agccccacaa gcatcccagc caccacaggc cccgccccag
      301 gccctgcccc agccaccacc cccagcagca ccccagcctc ctgctgcagc aaccccccag
      361 ccccagtatg tcaccgagct gcaaagcccc cagccccaga cgcaacctcc aggcagccag
      421 aagcagtatg tggcagagct cccggctgct cctgcaccct cacagcctgc cacacctgcc
      481 ccatccccgg tggctcagca gtatatcgtg gtcaccgtct cggaaggtgc catgcgggct
      541 agtgagactg tgtcagaagc cagccccagt tccacggcaa gccagaccgg tgtccccacc
      601 caagtggtac agcaggtgca gggcacccag cagcggctgc tggtccaggc aagtgtgcag
      661 gccaagccag gccatgtgtc acccctgcag cttaccaaca tccaggtgcc acagcaggct
      721 ctccccacac agcacttggt ggtgcagagc ccggcgccag gctctaaggg tggccaagtt
      781 tccttgacgg tgcacagcac gcagcaggtg cactctgccc ctgagaggtc accagtgcag
      841 gccaacaact ccaccagcaa gacagctggg actcctgccg gcactgtgca gcagctacag
      901 gtccacagtg tccagcagag tgtccctgtc acccaagaga ggtcagtagt ccaggccact
      961 ccacagacca aagctggccc agtgcagcag ctgactgtgc agggactgca gccagttcac
     1021 gttgctcaag aggtacagca actcccgcag gtgcctgtcc cacatgtgta ctccagccag
     1081 gtgcagtacg tggaaggtgg cgacgccagc tacacagcca gcgccatccg ctctagcacc
     1141 taccagtacc ctgagacgcc gatctatacg cagacagcag gcaccagcta ctatgaggct
     1201 tcaggcacgg ctgcccaggt cagcacgccc gctacttccc agacggtggc cagcagcggc
     1261 tcggtgccca tgtacgtatc cggcagcccg attgtcgcca gctcatccag cagcgaggct
     1321 ggggccagca acagcagtgt gggtgccggg ggcaacgggg gaggtggcag cggcggcggc
     1381 ggtggcggca gcagcggcgg cggcagtggg gcaggcacct atgtgatcca aggcggctac
     1441 atgctcggca acgccagcca gtcttactcc cacaccaccc gtgcctcgcc agccacagtc
     1501 cagtggctcc tggataatta cgagaccgct gagggcgtga gcctgccgcg gagcaccctc
     1561 tactgccact acctgctgca ctgccaggaa cagaagctgg agccggttaa cgctgcctcc
     1621 ttcggcaagc tcatccgctc cgtattcatg ggtctgcgta cgcgccgtct gggcaccagg
     1681 ggcaactcta agtaccacta ttacggcctg cggatcaaag ccagctcacc cctgctgcgg
     1741 ctgatggagg accagcagca catggccatg cgaggccaac cgttctccca gaaacagagg
     1801 ctcaagccca tccagaagat ggagggcgtg gccaacggtg ttgctgtggg gcagcagagc
     1861 acagggctgt cggacatcag cgctcaggtg cagcagtacc agcagttcct ggatgcctcc
     1921 aggagcctcc ctgattttgc tgagctggac ctccagggca aagtgctgcc tgagggtgtc
     1981 ggtcctgggg acatcaaggc cttccaggtc ctgtaccggg agcactgtga ggccattgtg
     2041 gacgtcatgg taaatctcca gtttacactg gtagaaacgc tgtggaagac cttctggaga
     2101 tataacctta gccagcctaa cgaggcacca ccactggccg tgcatgatga ggcagagaag
     2161 cggctgccca gggccagtct ggtgctcctc tccaagttcc agcctgtgct tcagtggacc
     2221 aagcactgtg acaatgtgct gtaccagggc ctggtggaga tccttatccc tgatgttctg
     2281 cggcccatcc ccagtgcctt gacccaagca atccggaact ttgccaagag cctggagagc
     2341 tggctgaccc atgccatggt gaacatccct gaggagatgc tgcgggtgaa ggtggcagca
     2401 gccggcgcct tcgcacagac gctgcggcgc tacacatcgc tcaaccactt ggcacaggca
     2461 gcgcgcgcag tgctgcagaa cactgcccag atcaaccaga tgctaagcga cctcaatcga
     2521 gtggacttcg caaatgtcca ggagcaggcc tcgtgggtgt gtcgctgcga ggaccgtgtg
     2581 gtgcagcgtc tggagcagga cttcaaggtg acgctgcagc agcagaactc actggagcag
     2641 tgggcagcct ggctggatgg cgttgtgagc caggtgctca agccctacca gggcagttcc
     2701 ggcttcccca aggcggccaa gctcttcctc ctcaagtggt ccttctacag ctccatggta
     2761 atccgggacc tgaccctgcg cagtgctgcc agctttggct ccttccacct catccggctg
     2821 ctctatgacg agtacatgta ctacctgatc gagcacagag tggcccaggc caagggcgag
     2881 accccaatcg cagtcatggg agagtttgca aacctggcca cctcactgaa tcccttggac
     2941 cctgacaaag atgaggaaga ggaggaggaa gaggagagtg aggacgagct gccacaagac
     3001 atctcactgg ctgctggcag cgagtccccc gcactaggcc cagaaactct ggaaccacca
     3061 gcgaaactgg cgcggactga cactcgtggc ctctttgtgc aggccctgcc ctccagctaa
     3121 gcctgagacc tccctgcacc cctccacccg cccaacctgc tgctgctgcc cctccaggcc
     3181 agggtccggt ccttcagttt ttgtggcttc actgtcaccc ttccagcaca tgccagagct
     3241 ggagagggtt cccctgatag ggaaggctaa gagagtctcc cctatatggg gctggtacaa
     3301 tcatgggcgg ggctgggcag aaccgaagct gcaaaccctg acacaaaaga tgtgccttaa
     3361 ggaacctgcc caggtgtccc tccttcctgc cccagctcac agcccggtcc cccaccacta
     3421 ccactccaga gggcagcagg ccagctcctc ccctgcggaa ctgttaactt attctgctct
     3481 ctggctttgc acagcctgcc tgagtaggcg caggtgggta gcaccttggg acccccgtca
     3541 gcagcagtac cccgctgctc ccctttcttg gtataagtgc aattaaagct gtgggtgttg
     3601 caccttctcc agagctgggt tctcctggcc ccgcagccca gagaggggca cattgtgaag
     3661 ggccccggcc tccagcttcc aaagaggagc atctggctgg ctgcagggcc aggtgctcca
     3721 gacccaaggc ctcgccctgc gccttccacc ccatcagctt gtgaccgaaa cctgctccca
     3781 gagatgcttc tcctccgtgc agtgccccga cccccgtaac tattgtgtga ttagtgagtg
     3841 ccgcttgagc ggagtcagta acttgttggg tttttttcca accatcatgg ccttatccgt
     3901 tcccgttttc tcagtgtctt caatctgtga tagatgttta tgaagaaaaa aagaaaatct
     3961 ggcctattgt atagaaatca ctattttgtg tgctccgcgt gctacagctt ttggggtggt
     4021 cctgcacact ccccatgggc ctcccttccc agtggtcaga gtacccacgc gcgtggtagt
     4081 tttagtgtgc tgttttctac cttttttgta gtctttctta aaacaataaa tactgctgtg
     4141 atctttgtct actgat
//
