LOCUS       NM_001014106            2235 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus riboflavin kinase (Rfk), mRNA.
ACCESSION   NM_001014106 XM_228521
VERSION     NM_001014106.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2235)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 2235)
  AUTHORS   Yazdanpanah,B., Wiegmann,K., Tchikov,V., Krut,O., Pongratz,C.,
            Schramm,M., Kleinridders,A., Wunderlich,T., Kashkar,H.,
            Utermohlen,O., Bruning,J.C., Schutze,S. and Kronke,M.
  TITLE     Riboflavin kinase couples TNF receptor 1 to NADPH oxidase
  JOURNAL   Nature 460 (7259), 1159-1163 (2009)
   PUBMED   19641494
REFERENCE   3  (bases 1 to 2235)
  AUTHORS   Kasai,S., Nakano,H., Maeda,K. and Matsui,K.
  TITLE     Purification, properties, and function of flavokinase from rat
            intestinal mucosa
  JOURNAL   J Biochem 107 (2), 298-303 (1990)
   PUBMED   2163401
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079125.1.
            
            On Apr 1, 2005 this sequence version replaced XM_228521.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079125.1, FQ223869.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2235
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..2235
                     /gene="Rfk"
                     /note="riboflavin kinase"
                     /db_xref="GeneID:499328"
                     /db_xref="RGD:1549748"
     exon            1..340
                     /gene="Rfk"
                     /inference="alignment:Splign:2.1.0"
     CDS             259..726
                     /gene="Rfk"
                     /EC_number="2.7.1.26"
                     /codon_start=1
                     /product="riboflavin kinase"
                     /protein_id="NP_001014128.1"
                     /db_xref="GeneID:499328"
                     /db_xref="RGD:1549748"
                     /translation="MRSLPFFCRGQVVRGFGRGSKQLGIPTANFPEQVVDNLPADVST
                     GIYYGWASVGSGEVHKMVVSIGWNPYYKNVKKSMETHIIHTFKEDFYGEILNVAIVGY
                     LRPEKNFDSLESLISAIQGDIEEAKKQLDLPEHLKLKDDNFFQVSKSKIMNGH"
     exon            341..492
                     /gene="Rfk"
                     /inference="alignment:Splign:2.1.0"
     exon            493..595
                     /gene="Rfk"
                     /inference="alignment:Splign:2.1.0"
     exon            596..2211
                     /gene="Rfk"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggaagccga gcaggccggt cgcctgggcc gcagatccgt gcgttctctg cggttgtcgc
       61 aattccgacc gagagacctc tgggttcttg gcggctggcg gctgtcctgc cggcaggcac
      121 cggtagcggc gggtgtcccg ctccgccggc ccagctcctg cggaatcccc ggctggtccg
      181 ggccggagtg ccgcactcac ggcggctccg tcgcaggcac ggagcgagga gcagcccgcg
      241 tcctccgagg tcagcgtcat gaggagcctg ccgttcttct gccgaggtca ggtggtgcgt
      301 ggcttcggcc gcggctccaa gcaactgggc atccccacag ccaattttcc tgaacaagta
      361 gtagacaatc ttccagctga tgtgtccact ggcatctatt acggctgggc cagcgttggg
      421 agtggagagg tccataaaat ggtggtgagc ataggatgga atccatacta caagaatgtg
      481 aagaagtcca tggaaaccca tatcatccat accttcaaag aggactttta tggggagatt
      541 ctcaatgtgg ccattgttgg ctacctcaga cctgaaaaga actttgattc tttagagtca
      601 cttatttctg cgattcaagg tgatattgaa gaagctaaaa aacaactgga tttaccagaa
      661 catttgaaac tcaaagatga caatttcttc caagtttcta aaagcaaaat tatgaatggc
      721 cactgatgaa aagtctcgta cctgtccacc cactagtgtc ttagtgcttc tgatacagtc
      781 tcatcttgat catagtttaa atcaagtgtt tccttgtagc tgtcaagagg tctccagcag
      841 ttaactccat catgttgcat agaaaaagat tcattcagaa atcaaggctt taaatgtaat
      901 gtgttgatta aaatgtagca ctagaaagct agtgtcttgt aatgaaaata aagtctgtga
      961 gtgtgggtgg aaaagcaagt tactaaggaa aatgaggact ggccatagtt cctgtgacca
     1021 tgtgtgctgg cactggcaag cctgacaagc atgtactgct gaatagacgc cttccaggaa
     1081 acgcaccact tacacagctt agccaaggag ggaaatctag agttactttt attattttgt
     1141 gcattaatat atttttacag tccttcaaac tttcatgagc cgtgagtcac tcattcctta
     1201 tgcggtcact tcctggtagt gtcctaatgc tctgtgtgga gttaacttca ggttgaagtg
     1261 cccttgatgg ccccgcacca gggcttttct gcacagtact gaggatccaa cccagtgcct
     1321 tacatggtag gcaagtgtga ccactgagca aggctcctgg ccccctttac ttttttaagc
     1381 catatgacgt ctctgtgtcg cctttttgaa gaatagatgt ttttgctctt tttatgactt
     1441 tggtttattt tcttcccatt tggcatatcc gacaaccatg tggcgtagag actgcttgtg
     1501 ggtgtgccgt tctgctcaaa actaagtggt ggtcaggtgc aagtatgctt tgtgttttaa
     1561 gaaaaataaa agaagctgta tttatagact tgcttggaat tgaaacggac ccagccagtt
     1621 cctacccaac ccagctctgt cttttttttt ttttttttta aaaacagtgt ggtcttatgt
     1681 tttcaaagta aaaatagttc tctatgacca agtacttaaa tataatttaa tactcatcta
     1741 aagcctttgc agcttcagaa gtggagaaag ttttagccgc gtatctttat atctcctggt
     1801 ttctcactga attggcttga gttgcctatg ctggcagaag gttgacattg ggcgaccaat
     1861 tgctttgggc tcatcagtgc gttgaattag ttgttgaatg gcgagagatt tgctggggca
     1921 gccctgtgaa tgtgttctat gactgagcaa cctccttagc cttcaaaata gaatttttga
     1981 tgttggaaat tccatactaa aaggaagcct taagtaagaa tagcttgtta attatgtcct
     2041 cattaagtaa tgttcatggc taatgtcaca ttgttaacag ttgttacttt ggaattatat
     2101 ggcatgtggt ttagggctta gttaattctc tagacttcaa aaactgtatt attgatgtat
     2161 tataagaaat tacagtacca ctttgattag tctgaatgtt tgcagacctt gaaaaaaaaa
     2221 aaaaaaaaaa aaaaa
//
