LOCUS       NM_001105869            1265 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus replication factor C subunit 4 (Rfc4), mRNA.
ACCESSION   NM_001105869 XM_001056509 XM_213598
VERSION     NM_001105869.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1265)
  AUTHORS   Vannier JB, Sandhu S, Petalcorin MI, Wu X, Nabi Z, Ding H and
            Boulton SJ.
  TITLE     RTEL1 is a replisome-associated helicase that promotes telomere and
            genome-wide replication
  JOURNAL   Science 342 (6155), 239-242 (2013)
   PUBMED   24115439
REFERENCE   2  (bases 1 to 1265)
  AUTHORS   Hedglin M, Kumar R and Benkovic SJ.
  TITLE     Replication clamps and clamp loaders
  JOURNAL   Cold Spring Harb Perspect Biol 5 (4), a010165 (2013)
   PUBMED   23545418
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1265)
  AUTHORS   Lee KY, Fu H, Aladjem MI and Myung K.
  TITLE     ATAD5 regulates the lifespan of DNA replication factories by
            modulating PCNA level on the chromatin
  JOURNAL   J Cell Biol 200 (1), 31-44 (2013)
   PUBMED   23277426
REFERENCE   4  (bases 1 to 1265)
  AUTHORS   Li GM.
  TITLE     Mechanisms and functions of DNA mismatch repair
  JOURNAL   Cell Res 18 (1), 85-98 (2008)
   PUBMED   18157157
  REMARK    Review article
REFERENCE   5  (bases 1 to 1265)
  AUTHORS   Bermudez VP, Maniwa Y, Tappin I, Ozato K, Yokomori K and Hurwitz J.
  TITLE     The alternative Ctf18-Dcc1-Ctf8-replication factor C complex
            required for sister chromatid cohesion loads proliferating cell
            nuclear antigen onto DNA
  JOURNAL   Proc Natl Acad Sci U S A 100 (18), 10237-10242 (2003)
   PUBMED   12930902
REFERENCE   6  (bases 1 to 1265)
  AUTHORS   Ellison V and Stillman B.
  TITLE     Reconstitution of recombinant human replication factor C (RFC) and
            identification of an RFC subcomplex possessing DNA-dependent ATPase
            activity
  JOURNAL   J Biol Chem 273 (10), 5979-5987 (1998)
   PUBMED   9488738
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC168166.1.
            
            On Aug 10, 2008 this sequence version replaced NM_001105869.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168166.1, FQ228232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1265
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..1265
                     /gene="Rfc4"
                     /note="replication factor C subunit 4"
                     /db_xref="GeneID:288003"
                     /db_xref="RGD:1310142"
     exon            1..26
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            27..168
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1132
                     /gene="Rfc4"
                     /note="replication factor C (activator 1) 4"
                     /codon_start=1
                     /product="replication factor C subunit 4"
                     /protein_id="NP_001099339.1"
                     /db_xref="GeneID:288003"
                     /db_xref="RGD:1310142"
                     /translation="MQAFLKGTSVSTKPQLTKERGISSSAGSSGETKKVKPVPWVEKY
                     RPKCVDEVAFQEEVVAVLKKSLEGADLPNLLFYGPPGTGKTSTILAAARELFGPELFR
                     LRVLELNASDERGIQVVREKVKNFAQLTVSGSRSDGKPCPPFKIVILDEADSMTSAAQ
                     AALRRTMEKESKTTRFCLICNYVSRIIEPLTSRCSKFRFKPLSDKIQQKRLLDIAEKE
                     NVKIGDEEIAYLVRISEGDLRKAITFLQSATRLTGGKEISEDVITDIAGVIPAATIEG
                     IVTACHSGSFDKLEAVLKNLIDEGHAATQLVNQLHDSIIEDENLSDKQKSIITEKLAE
                     VDKCLADGADEHLQLMSLCATVMQQLTQNC"
     exon            169..247
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            248..327
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            328..447
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            448..591
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            592..712
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            713..838
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            839..919
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1036
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1184
                     /gene="Rfc4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcaccag ggggacggcg acaactgaga agaaaccatg caagcatttc tgaaaggcac
       61 atctgtcagt accaaaccac aattgaccaa ggaacggggc atatcttcct ctgcaggaag
      121 cagtggagaa accaagaaag tcaaaccagt tccttgggtg gaaaaatacc gtccgaagtg
      181 cgtggatgaa gttgctttcc aggaagaagt ggttgcagtg ctgaaaaagt ctttagaagg
      241 agctgatctt cctaatctct tgttctatgg gccacctgga actggcaaaa catccaccat
      301 tttggcagca gctagagagc tctttgggcc tgaactcttt cgattaagag tccttgagtt
      361 aaatgcatct gatgaacgtg gaatacaagt agtccgagag aaagtgaaaa actttgctca
      421 gttaactgtg tctggaagtc gttcagatgg gaaaccatgt cctcccttta agattgtaat
      481 tctggatgaa gcagattcta tgacttcagc tgctcaggca gctttaagac gaaccatgga
      541 aaaagagtct aaaacaacca gattctgcct catctgtaac tatgtcagcc gaataattga
      601 acccctcact tctagatgtt caaaattccg cttcaagcct ctgtcagata aaattcaaca
      661 gaagcgatta ttggatattg ctgagaagga aaatgtcaaa attggcgatg aggaaatagc
      721 ttatcttgtt agaatatcag aaggagattt acggaaagca attacatttc ttcaaagtgc
      781 tactcgacta acaggtggaa aggaaatctc ggaagatgtg atcacagaca ttgctggggt
      841 aataccagct gcaaccattg agggaatagt cactgcatgt cacagcggct cttttgacaa
      901 actagaagcc gtgctgaaga acctaataga tgaagggcat gcagccactc agcttgtcaa
      961 ccaacttcat gattcaatca tagaagatga aaatctgtct gataaacaga agtccatcat
     1021 tacagaaaaa cttgctgagg tggataagtg tttagcagat ggtgcagatg agcacctgca
     1081 gctgatgagc ctctgcgcaa ctgtgatgca gcaactgacc cagaactgtt aagatcgatg
     1141 ttcttttgta tgaataatag aaataaagga ccaaaccacc tgtaaaaaaa aaaaaaaaaa
     1201 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1261 aaaaa
//
