LOCUS       NM_053786               1556 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus replication factor C subunit 2 (Rfc2), mRNA.
ACCESSION   NM_053786 XM_341062 XM_347153
VERSION     NM_053786.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1556)
  AUTHORS   Vannier,J.B., Sandhu,S., Petalcorin,M.I., Wu,X., Nabi,Z., Ding,H.
            and Boulton,S.J.
  TITLE     RTEL1 is a replisome-associated helicase that promotes telomere and
            genome-wide replication
  JOURNAL   Science 342 (6155), 239-242 (2013)
   PUBMED   24115439
REFERENCE   2  (bases 1 to 1556)
  AUTHORS   Hedglin,M., Kumar,R. and Benkovic,S.J.
  TITLE     Replication clamps and clamp loaders
  JOURNAL   Cold Spring Harb Perspect Biol 5 (4), a010165 (2013)
   PUBMED   23545418
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1556)
  AUTHORS   Li,G.M.
  TITLE     Mechanisms and functions of DNA mismatch repair
  JOURNAL   Cell Res 18 (1), 85-98 (2008)
   PUBMED   18157157
  REMARK    Review article
REFERENCE   4  (bases 1 to 1556)
  AUTHORS   Bermudez,V.P., Maniwa,Y., Tappin,I., Ozato,K., Yokomori,K. and
            Hurwitz,J.
  TITLE     The alternative Ctf18-Dcc1-Ctf8-replication factor C complex
            required for sister chromatid cohesion loads proliferating cell
            nuclear antigen onto DNA
  JOURNAL   Proc Natl Acad Sci U S A 100 (18), 10237-10242 (2003)
   PUBMED   12930902
REFERENCE   5  (bases 1 to 1556)
  AUTHORS   Chim,S.S., Fung,K., Waye,M.M., Lee,C. and Tsui,S.K.
  TITLE     Expression of replication factor C 40-kDa subunit is down-regulated
            during neonatal development in rat ventricular myocardium
  JOURNAL   J Cell Biochem 78 (4), 533-540 (2000)
   PUBMED   10861850
REFERENCE   6  (bases 1 to 1556)
  AUTHORS   Ellison,V. and Stillman,B.
  TITLE     Reconstitution of recombinant human replication factor C (RFC) and
            identification of an RFC subcomplex possessing DNA-dependent ATPase
            activity
  JOURNAL   J Biol Chem 273 (10), 5979-5987 (1998)
   PUBMED   9488738
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC082110.1.
            
            On or before Nov 26, 2004 this sequence version replaced
            XM_341062.1, XM_347153.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC082110.1, SRR8487227.147001.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1556
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q12"
     gene            1..1556
                     /gene="Rfc2"
                     /note="replication factor C subunit 2"
                     /db_xref="GeneID:116468"
                     /db_xref="RGD:621198"
     exon            1..135
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1087
                     /gene="Rfc2"
                     /note="activator 1 subunit C2; replication factor C
                     (activator 1) 2"
                     /codon_start=1
                     /product="replication factor C subunit 2"
                     /protein_id="NP_446238.1"
                     /db_xref="GeneID:116468"
                     /db_xref="RGD:621198"
                     /translation="MEVQESGSGSAESGTQEPSPVPSKTTGHYELPWVEKYRPVKLNE
                     IVGNEDTVSRLEVFAREGNVPNIIIAGPPGTGKTTSILCLARALLGPALKDAVLELNA
                     SNDRGIDVVRNKIKMFAQQKVTLPKGRHKIIILDEADSMTDGAQQALRRTMEIYSKTT
                     RFALACNASDKIIEPIQSRCAVLRYTKLTDAQVLSRLMNVIEKEKVPYTDDGLEAIIF
                     TAQGDMRQALNNLQSTFSGFGYINSENVFKVCDEPHPLLVKEMIQHCVDANIDEAYKI
                     LAHLWHLGYSPEDVIGNIFRVCKTFPMAEYLKLEFIKEIGYTHMKVAEGVNSLLQMAG
                     LLARLCQKTMAPVAS"
     exon            136..205
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            206..247
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            248..354
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            355..456
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            457..557
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            558..715
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            716..781
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            782..862
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            863..976
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1528
                     /gene="Rfc2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggagctt cgggtggcgg gaagagcagg caccggaatg gaggttcagg agagcggcag
       61 tggctcggct gagagtggga cgcaggagcc ctcgcctgtc cccagcaaga ccaccggcca
      121 ctacgagctg ccgtgggttg aaaaatacag accagtgaag ctcaatgaaa tagtgggaaa
      181 cgaagacact gtgagcaggc tggaggtctt tgcaagagaa ggcaatgtac ccaatatcat
      241 catcgctggc cctccaggaa ctggcaagac aaccagcatc ctctgcttgg cgagagcgct
      301 gctgggcccg gccctgaagg atgcagttct ggaactcaat gcgtccaacg acaggggcat
      361 cgatgtggta aggaataaaa tcaaaatgtt cgcccagcag aaagtcaccc ttcccaaggg
      421 ccgacacaag atcatcattc tggatgaggc agacagcatg acggatggtg cccagcaggc
      481 cctcaggaga accatggaaa tctactccaa aacgactcgc ttcgctctgg cttgtaatgc
      541 ttcagacaaa atcatagagc ccatccagtc ccgctgtgcg gtgctccgct acaccaagct
      601 caccgatgca caggtcctca gcaggctcat gaatgtcatc gagaaggaaa aagtgccata
      661 cacagatgac ggcctggaag ccatcatttt cacagcccag ggagacatgc gccaggctct
      721 gaacaacttg cagtccacct tctcaggatt tggctatatc aacagcgaga atgtattcaa
      781 ggtctgtgac gagccccacc ccctgctggt gaaggagatg atccagcact gtgtggacgc
      841 caacattgat gaggcctata agattcttgc tcacctgtgg cacctgggct actcgccaga
      901 agatgtcatc ggcaatattt tccgtgtgtg taaaaccttc ccaatggctg aatacttgaa
      961 actggagttc atcaaggaga ttggatacac ccacatgaaa gtggccgaag gagtgaactc
     1021 cctgctgcag atggccgggc tcctggccag gctgtgtcag aagaccatgg ctccggtggc
     1081 cagctgactt gagacgccct tcactaatgg aattaggaga atccttgtcg ccgagacact
     1141 gatgttccag ctttccactt gtgggagaag tgccttagcc tttgctagaa catgctctgt
     1201 ttttcttctg tgagaatagg gtctcttgta gcccaggctg acattgaact cctgacctcc
     1261 ctcccagctc tgcctgccga gtactagagt cacaggtgtg tgtcctgctt gctttatgca
     1321 ggactacgga tggagcccac agcttgtgct tgtcagctgg gcgacagtga gagactgagc
     1381 tctggaagat ttcctcatgg ctaccgatac acgtctgctc ttcagtgtgt gaatatggcc
     1441 tcaggccctg gacatgggca tggtgggaaa gctttgacct cctcagtctt gttgtagctg
     1501 ataaagcctt tggatgtttg tctttgaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
