LOCUS       NM_001008326            1185 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus RNA exonuclease 2 (Rexo2), mRNA; nuclear gene for
            mitochondrial product.
ACCESSION   NM_001008326 XM_217137
VERSION     NM_001008326.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1185)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   2  (bases 1 to 1185)
  AUTHORS   Nguyen,L.H., Erzberger,J.P., Root,J. and Wilson,D.M. 3rd.
  TITLE     The human homolog of Escherichia coli Orn degrades small
            single-stranded RNA and DNA oligomers
  JOURNAL   J Biol Chem 275 (34), 25900-25906 (2000)
   PUBMED   10851236
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001008326.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086420.1, CF114237.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676787 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-298               JAXUCZ010000008.1  57719845-57720142   c
            299-382             JAXUCZ010000008.1  57718851-57718934   c
            383-460             JAXUCZ010000008.1  57714437-57714514   c
            461-572             JAXUCZ010000008.1  57713701-57713812   c
            573-681             JAXUCZ010000008.1  57712283-57712391   c
            682-735             JAXUCZ010000008.1  57710645-57710698   c
            736-1185            JAXUCZ010000008.1  57708420-57708869   c
FEATURES             Location/Qualifiers
     source          1..1185
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q23"
     gene            1..1185
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /note="RNA exonuclease 2"
                     /db_xref="GeneID:300689"
                     /db_xref="RGD:1304874"
     exon            1..298
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..865
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /note="oligoribonuclease, mitochondrial; RNA exonuclease 2
                     homolog; small fragment nuclease; REX2, RNA exonuclease 2
                     homolog"
                     /codon_start=1
                     /product="oligoribonuclease, mitochondrial precursor"
                     /protein_id="NP_001008327.1"
                     /db_xref="GeneID:300689"
                     /db_xref="RGD:1304874"
                     /translation="MLGVSLGARLLRGVGGRRGQFGARGVSEGSAAMAAGESMAQRMV
                     WVDLEMTGLDIEKDQIIEMACLITDSDLNILAEGPNLIIKQPDELLDSMSDWCKEHHG
                     KSGLTKAVKESTVTLQQAEYEFLSFVRQQTPPGLCPLAGNSVHADKKFLDKHMPQFMK
                     HLHYRIIDVSTVKELCRRWYPEDYEFAPKKAASHRALDDISESIKELQFYRNNIFKKK
                     TDEKKRKIIENGENEKPVS"
     exon            299..382
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /inference="alignment:Splign:2.1.0"
     exon            383..460
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /inference="alignment:Splign:2.1.0"
     exon            461..572
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /inference="alignment:Splign:2.1.0"
     exon            573..681
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /inference="alignment:Splign:2.1.0"
     exon            682..735
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /inference="alignment:Splign:2.1.0"
     exon            736..1185
                     /gene="Rexo2"
                     /gene_synonym="Smfn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agcgtagctg tggagggcga gctgacacct agcatgccgg ggattgtagt cttctcccgg
       61 cacctccccg tgggtttgcg acgtttagcg actgtggcgc ctgcgcgcgc tgggccggcg
      121 gggctggggc cgtggcggct cgtgccgggt gatgctaggc gtatccctgg gcgccaggct
      181 gttgcggggc gtgggtggta ggcgcgggca gttcggggcg cgaggtgtca gcgaaggtag
      241 cgcagccatg gcggcagggg agagcatggc tcagcgaatg gtctgggtgg acctggagat
      301 gacaggattg gacattgaga aggatcagat tattgagatg gcttgtctga taactgactc
      361 tgaccttaac attttggctg aaggtcccaa cctgattatc aaacagccgg atgagttgct
      421 ggacagcatg tcagattggt gcaaggagca tcacgggaag tctggtctta ccaaggccgt
      481 gaaggagagt acagttacac tgcagcaggc agagtatgaa tttctgtcct ttgtacgaca
      541 gcagactcct ccggggctct gtccacttgc agggaactca gttcatgcag ataagaagtt
      601 tcttgacaaa cacatgcccc agttcatgaa acatcttcac tataggataa ttgatgtgag
      661 cactgttaaa gagctgtgca gacgctggta tccggaagat tatgaatttg caccgaagaa
      721 ggctgcttct cacagggcac tggatgacat tagcgaaagc atcaaagagc ttcagtttta
      781 ccgaaataac atcttcaaga aaaagacaga tgaaaagaag aggaaaatta tagaaaatgg
      841 ggaaaatgag aagcccgtga gttgatgcca gttctcaagc cgcagagcct ggctctcaga
      901 agccacttta gcgtctctct ctctctctcc cgccgaccac tcggcacggc accttttcta
      961 aagaaaaaaa aaattctttt ttccagttaa ctttgcatct tcagactcct ccagcagacg
     1021 agacatcact attccgttcc ttctagtctg ctgtttccgt cgcgagacgg cggcgccttt
     1081 gtaagcttca ggccacgccc acccccctca gtccgtatct gcacttgctt ataggccatt
     1141 ccttttgttt gaataataaa taaagctagt tctattgaaa tgcaa
//
