LOCUS       NM_145084               1855 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus retinol saturase (Retsat), mRNA.
ACCESSION   NM_145084 XM_346698
VERSION     NM_145084.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 1855)
  AUTHORS   Moise,A.R., Kuksa,V., Imanishi,Y. and Palczewski,K.
  TITLE     Identification of all-trans-retinol:all-trans-13,14-dihydroretinol
            saturase
  JOURNAL   J Biol Chem 279 (48), 50230-50242 (2004)
   PUBMED   15358783
REFERENCE   3  (bases 1 to 1855)
  AUTHORS   Wang,Y., Hu,L., Yao,R., Wang,M., Crist,K.A., Grubbs,C.J.,
            Johanning,G.L., Lubet,R.A. and You,M.
  TITLE     Altered gene expression profile in chemically induced rat mammary
            adenocarcinomas and its modulation by an aromatase inhibitor
  JOURNAL   Oncogene 20 (53), 7710-7721 (2001)
   PUBMED   11753649
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF465614.1.
            
            On Sep 24, 2004 this sequence version replaced XM_346698.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF465614.1, SRR8487227.92344.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132263, SAMD00132264
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q32"
     gene            1..1855
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /note="retinol saturase"
                     /db_xref="GeneID:246298"
                     /db_xref="RGD:628802"
     CDS             1..1830
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /EC_number="1.3.99.23"
                     /note="all-trans-retinol 13,14-reductase;
                     all-trans-13,14-dihydroretinol saturase; RMT-7;
                     PPAR-alpha-regulated and starvation-induced gene protein;
                     hypothetical protein RMT-7; retinol saturase (all trans
                     retinol 13,14 reductase)"
                     /codon_start=1
                     /product="all-trans-retinol 13,14-reductase precursor"
                     /protein_id="NP_659552.1"
                     /db_xref="GeneID:246298"
                     /db_xref="RGD:628802"
                     /translation="MWITALLLVVLLLVVVHRVYVGLFTGSSPNPFAEDVKRPPEPLV
                     TDKEARKKVLKQAFSVSRVPEKLDAVVIGSGIGGLASAAVLAKAGKRVLVLEQHTKAG
                     GCCHTFGENGLEFDTGIHYIGRMREGNIGRFILDQITEGQLDWAPMASPFDLMILEGP
                     NGRKEFPMYSGRKEYIQGLKEKFPKEEAVIDKYMELVKVVAHGVSHAILLKFLPLPLT
                     QLLNKFGLLTRFSPFCRASTQSLAEVLKQLGASPELQAVLSYILPTYGVTPSHTTFSL
                     HALLVDHYIQGAYYPRRGSSEIAFHTIPLIQRAGGAVLTRATVQSVLLDSAGRACGVS
                     VKKGQELVNIYCPVVISNAGMFNTYQHLLPESVRYLPDVKKQLTMVKPGLSMLSIFIC
                     LKGTKEELKLQSTNYYVYFDTDMDKAMECYVSMPKEKAPEHIPLLFIPFPSSKDPTWE
                     DRFPDRSTMTVLVPTAFEWFEEWQEEPKGKRGVDYETLKNTFREASMSVIMKLFPQLE
                     GKVESVTGGSPLTNQYYLAAHRGATYGADHDLARLHPHAMASLRAQTPIPNLYLTGQD
                     IFTCGLMGALQGALLCSSAILKRNLYSDLQALGSKVRAQKKKK"
     exon            1..169
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            170..352
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            353..594
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            595..796
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            797..994
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1114
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1253
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            1254..1363
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            1364..1530
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            1531..1690
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1855
                     /gene="Retsat"
                     /gene_synonym="Rmt7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtggatca ctgctctgct gctggtcgtg ctgctgctgg tggtcgttca cagggtttat
       61 gtgggccttt tcaccggaag ttccccgaac cccttcgctg aggatgtcaa gcggccacct
      121 gaacccctag tgaccgacaa ggaggctagg aagaaagttc tcaaacaagc tttctcagtc
      181 agccgagtac cagagaagct ggacgcagtg gtgattggca gcggcattgg gggactggcc
      241 tcagctgcgg ttctagctaa agctggcaag agagtccttg tgctggaaca acacaccaag
      301 gcaggcggct gttgtcatac ctttggggaa aatggccttg aatttgacac tggaattcat
      361 tatattggac gaatgcggga gggcaacatt ggccgtttca tcttggacca gatcaccgaa
      421 gggcaactgg actgggcccc tatggcctcc ccttttgact tgatgatact agaaggaccc
      481 aatggccgaa aggagttccc catgtacagt gggaggaaag aatacatcca gggccttaag
      541 gagaagttcc ccaaggaaga ggctgtcatt gacaaataca tggagctggt taaggtggtg
      601 gcccatggag tctctcatgc catcctactg aagttcctcc cattgccctt gactcagctc
      661 ctcaacaagt ttgggctgct gactcgtttt tctccattct gccgagcgtc tactcagagc
      721 ctagctgaag tcctgaaaca gcttggggct tcccctgagc tccaggctgt tcttagctac
      781 attttaccca cttacggagt aacccccagc cataccacct tttccttgca cgctctgctg
      841 gttgaccact acatacaagg ggcatattac ccccgacggg gctccagtga gattgctttc
      901 cataccatcc ctttgattca gcgggccggg ggcgctgtcc tcaccagggc caccgtacag
      961 agtgtgctgc tggactcagc tgggagagcg tgcggtgtca gtgtgaagaa gggacaagag
     1021 ctggtgaaca tctactgccc agttgtcatc tccaatgcgg gaatgttcaa tacctatcag
     1081 cacctgttgc cagagtctgt ccgctacctg ccagatgtga agaagcagct gacaatggta
     1141 aagcctggtt tgagcatgct gtcaattttc atctgtctga agggcaccaa ggaggagctc
     1201 aagcttcagt ccaccaacta ctatgtttat tttgacacag acatggacaa agcgatggag
     1261 tgctatgtct ctatgcccaa ggaaaaggct ccagaacaca ttccccttct cttcattccc
     1321 ttcccatcaa gcaaggatcc aacctgggag gaccgattcc cagaccgatc cacaatgact
     1381 gtcctggtac ccacggcctt tgaatggttc gaggagtggc aggaggagcc taagggcaag
     1441 cgaggtgttg actatgagac cctcaaaaat accttccggg aagcctctat gtcggtgatc
     1501 atgaaactgt tcccacagct ggaaggcaag gtggagagtg tgactggagg atccccactg
     1561 accaaccagt actatctggc tgcacaccga ggagctactt atggggctga ccatgacctg
     1621 gctcgtctgc atcctcatgc aatggcttcc ctaagagccc aaacccccat ccccaacctc
     1681 tacctgacag gccaagatat cttcacctgt gggctgatgg gggccctgca aggggccctg
     1741 ctgtgcagca gtgccatcct gaaacggaac ctgtactcag atctgcaggc tcttggctca
     1801 aaggtcaggg cacaaaagaa gaagaagtag tctattcaga gatgagctag aggaa
//
