LOCUS       NM_181625                563 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus resistin-like gamma (Retnlg), mRNA.
ACCESSION   NM_181625 XM_006248282
VERSION     NM_181625.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 563)
  AUTHORS   Tian,H., Liu,L., Wu,Y., Wang,R., Jiang,Y., Hu,R., Zhu,L., Li,L.,
            Fang,Y., Yang,C., Ji,L., Liu,G. and Dai,A.
  TITLE     Resistin-like molecule beta acts as a mitogenic factor in hypoxic
            pulmonary hypertension via the Ca2+-dependent PI3K/Akt/mTOR and
            PKC/MAPK signaling pathways
  JOURNAL   Respir Res 22 (1), 8 (2021)
   PUBMED   33407472
  REMARK    GeneRIF: Resistin-like molecule beta acts as a mitogenic factor in
            hypoxic pulmonary hypertension via the Ca(2+)-dependent
            PI3K/Akt/mTOR and PKC/MAPK signaling pathways.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 563)
  AUTHORS   Gerstmayer,B., Kusters,D., Gebel,S., Muller,T., Van Miert,E.,
            Hofmann,K. and Bosio,A.
  TITLE     Identification of RELMgamma, a novel resistin-like molecule with a
            distinct expression pattern
  JOURNAL   Genomics 81 (6), 588-595 (2003)
   PUBMED   12782128
  REMARK    GeneRIF: revealed a repression of RELMgamma mRNA in nasal
            respiratory epithelium of cigarette smoke-exposed versus untreated
            rats; tissue-specific expression revealed highest expression in
            hematopoietic tissues, suggesting a cytokine-like role for
            RELMgamma
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On or before Oct 20, 2022 this sequence version replaced
            XM_006248282.4, NM_181625.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA509499.1, CA505605.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676789 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-54                JAXUCZ010000011.1  65395586-65395639   c
            55-206              JAXUCZ010000011.1  65395268-65395419   c
            207-287             JAXUCZ010000011.1  65394733-65394813   c
            288-563             JAXUCZ010000011.1  65393907-65394182   c
FEATURES             Location/Qualifiers
     source          1..563
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..563
                     /gene="Retnlg"
                     /gene_synonym="retn1g"
                     /note="resistin-like gamma"
                     /db_xref="GeneID:288135"
                     /db_xref="RGD:727934"
     exon            1..54
                     /gene="Retnlg"
                     /gene_synonym="retn1g"
                     /inference="alignment:Splign:2.1.0"
     exon            55..206
                     /gene="Retnlg"
                     /gene_synonym="retn1g"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..415
                     /gene="Retnlg"
                     /gene_synonym="retn1g"
                     /note="resistin-like beta; RELMgamma; resistin-like
                     molecule gamma"
                     /codon_start=1
                     /product="resistin-like gamma precursor"
                     /protein_id="NP_853656.2"
                     /db_xref="GeneID:288135"
                     /db_xref="RGD:727934"
                     /translation="MKTAICSLLICIFLLQLMVPVNTDGTLESIVEQKVKELLAHRDN
                     CPSTVTKTLSCTSVKATGRLASCPPGMAVTGCACGYACGSWDIRDGTTCHCQCAVMDW
                     ATARCCQLS"
     exon            207..287
                     /gene="Retnlg"
                     /gene_synonym="retn1g"
                     /inference="alignment:Splign:2.1.0"
     exon            288..563
                     /gene="Retnlg"
                     /gene_synonym="retn1g"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtgtattac agcatttcat ctggccaggt cctagaacct tccctgagat tctgccccag
       61 gacacggact ttcaacagga tgaagactgc aatctgttcc cttctcatct gcatctttct
      121 tctccagctg atggtcccag tgaatactga tggaacctta gagtctattg tggagcaaaa
      181 ggtcaaggaa cttcttgccc atcgagataa ctgtccctcc actgtaacga agactctctc
      241 ctgcactagt gtcaaggcta caggcagatt ggcctcctgt cctcctggaa tggctgtcac
      301 tggatgtgct tgtggctatg cctgtggatc ttgggatatc cgggatggaa ctacttgcca
      361 ctgccagtgc gcagtcatgg attgggccac tgcccgctgc tgccaactgt cctaagaatg
      421 tggaggctga gaacccggct ttgaaatgaa gactgtaaca gaagcacaat ctcaacttgg
      481 aaacctggcc catagcccct tgatgaaatc ttattgccca ttagccctgc ttcttgaaaa
      541 ataaagacta atttttgcat gtg
//
