LOCUS       NM_001024281             531 bp    mRNA    linear   ROD 03-SEP-2024
DEFINITION  Rattus norvegicus resistin like beta (Retnlb), mRNA.
ACCESSION   NM_001024281 XM_573275
VERSION     NM_001024281.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Wang,Y., Han,D., Chai,L., Qiu,Y., Liu,J., Li,D., Zhang,Q., Shen,N.,
            Chen,Y., Chen,H., Zhang,J., Wang,Q., Wang,J., Li,S., Xie,X. and
            Li,M.
  TITLE     MFN2-dependent mitochondrial dysfunction contributes to
            Relm-beta-induced pulmonary arterial hypertension via
            USP18/Twist1/miR-214 pathway
  JOURNAL   Eur J Pharmacol 980, 176828 (2024)
   PUBMED   39094924
  REMARK    GeneRIF: MFN2-dependent mitochondrial dysfunction contributes to
            Relm-beta-induced pulmonary arterial hypertension via
            USP18/Twist1/miR-214 pathway.
REFERENCE   2  (bases 1 to 531)
  AUTHORS   Hosoya,A., Takahama,A. and Nakamura,H.
  TITLE     Localization of RELM-beta/FIZZ2 Is Associated with Cementum
            Formation
  JOURNAL   Anat Rec (Hoboken) 300 (10), 1865-1874 (2017)
   PUBMED   28681425
  REMARK    GeneRIF: secreted by the inner dental enamel epithelium and became
            localized in the matrix at the surface of the apical root dentin;
            might be involved in cementogenesis
REFERENCE   3  (bases 1 to 531)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   4  (bases 1 to 531)
  AUTHORS   Gerstmayer,B., Kusters,D., Gebel,S., Muller,T., Van Miert,E.,
            Hofmann,K. and Bosio,A.
  TITLE     Identification of RELMgamma, a novel resistin-like molecule with a
            distinct expression pattern
  JOURNAL   Genomics 81 (6), 588-595 (2003)
   PUBMED   12782128
REFERENCE   5  (bases 1 to 531)
  AUTHORS   Steppan,C.M., Brown,E.J., Wright,C.M., Bhat,S., Banerjee,R.R.,
            Dai,C.Y., Enders,G.H., Silberg,D.G., Wen,X., Wu,G.D. and Lazar,M.A.
  TITLE     A family of tissue-specific resistin-like molecules
  JOURNAL   Proc Natl Acad Sci U S A 98 (2), 502-506 (2001)
   PUBMED   11209052
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY641429.1.
            
            On May 27, 2005 this sequence version replaced XM_573275.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY641429.1, CV796412.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..531
                     /gene="Retnlb"
                     /note="resistin like beta"
                     /db_xref="GeneID:498074"
                     /db_xref="RGD:1624215"
     exon            1..33
                     /gene="Retnlb"
                     /inference="alignment:Splign:2.1.0"
     exon            34..185
                     /gene="Retnlb"
                     /inference="alignment:Splign:2.1.0"
     CDS             59..376
                     /gene="Retnlb"
                     /codon_start=1
                     /product="resistin-like beta precursor"
                     /protein_id="NP_001019452.1"
                     /db_xref="GeneID:498074"
                     /db_xref="RGD:1624215"
                     /translation="MKPTLCFLFILIFLLSLMVPGNTQCSFESLVDQKIKKALSQQKT
                     KKLSCTSITAAGRLASCPVGMVVTGCACGYACGSWDIRDGTTCHCQCAVMDWVTARCC
                     QMV"
     exon            186..248
                     /gene="Retnlb"
                     /inference="alignment:Splign:2.1.0"
     exon            249..513
                     /gene="Retnlb"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgaagacctc aaaaacattt cctgagcttt ctgctctagg aggctgactt tctacaacat
       61 gaagcctaca ctgtgtttcc ttttcatcct catcttcctt ctctcgctga tggtcccagg
      121 gaacacgcag tgctcctttg agtctttggt ggatcaaaag atcaagaaag cactcagtca
      181 acaaaagact aagaagctct cctgcactag tatcacggct gctggcagac tggcttcctg
      241 tcctgttggg atggttgtca ctggttgtgc ttgtggctat gcctgtggat cttgggatat
      301 ccgggatgga actacttgcc actgccagtg tgcagtcatg gattgggtca ctgcccgctg
      361 ctgccaaatg gtttaagaat aaggaagctg agaatccagt tttaaaatga taagcatcat
      421 gaaaccatga tcttgacgag gaaacccgac tcattgtctt cataatgtat ccatattact
      481 aaataattgt tcttgaataa agacagatct gcaaaaaaaa aaaaaaaaaa a
//
