LOCUS       NM_012643               5478 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus ret proto-oncogene (Ret), transcript variant 1,
            mRNA.
ACCESSION   NM_012643
VERSION     NM_012643.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5478)
  AUTHORS   Kasanga,E.A., Han,Y., Navarrete,W., McManus,R., Shifflet,M.K.,
            Parry,C., Barahona,A., Manfredsson,F.P., Nejtek,V.A.,
            Richardson,J.R. and Salvatore,M.F.
  TITLE     Differential expression of RET and GDNF family receptor,
            GFR-alpha1, between striatum and substantia nigra following
            nigrostriatal lesion: A case for diminished GDNF-signaling
  JOURNAL   Exp Neurol 366, 114435 (2023)
   PUBMED   37178997
  REMARK    GeneRIF: Differential expression of RET and GDNF family receptor,
            GFR-alpha1, between striatum and substantia nigra following
            nigrostriatal lesion: A case for diminished GDNF-signaling.
REFERENCE   2  (bases 1 to 5478)
  AUTHORS   Kearon,J.E., Kocherry,S.C., Zoumboulakis,D., Rivera,D.,
            Lourenssen,S.R. and Blennerhassett,M.G.
  TITLE     GDNF requires HIF-1alpha and RET activation for suppression of
            programmed cell death of enteric neurons by metabolic challenge
  JOURNAL   Mol Cell Neurosci 115, 103655 (2021)
   PUBMED   34273501
  REMARK    GeneRIF: GDNF requires HIF-1alpha and RET activation for
            suppression of programmed cell death of enteric neurons by
            metabolic challenge.
REFERENCE   3  (bases 1 to 5478)
  AUTHORS   Hu,X.B., Fu,S.H., Luo,Q.I., He,J.Z., Qiu,Y.F., Lai,W. and Zhong,M.
  TITLE     Down-regulation of microRNA-216a confers protection against yttrium
            aluminium garnet laser-induced retinal injury via the GDNF-mediated
            GDNF/GFRalpha1/RET signalling pathway
  JOURNAL   J Biosci 43 (5), 985-1000 (2018)
   PUBMED   30541958
  REMARK    GeneRIF: The findings demonstrate that elevated GDNF levels can
            reduce the retinal injury, whereby down-regulated miR-216a
            aggravates the YAG laser-induced retinal injury by targeting the
            GDNF level through the GDNF/GFRa1/RET signaling pathway.
REFERENCE   4  (bases 1 to 5478)
  AUTHORS   Pertile,R.A.N., Cui,X., Hammond,L. and Eyles,D.W.
  TITLE     Vitamin D regulation of GDNF/Ret signaling in dopaminergic neurons
  JOURNAL   FASEB J 32 (2), 819-828 (2018)
   PUBMED   29018141
  REMARK    GeneRIF: the inverse relationship between GFRalpha1 and C-Ret, as
            knocking down C-Ret led to increases in GFRalpha1 expression.
REFERENCE   5  (bases 1 to 5478)
  AUTHORS   Hsu,J.Y., Crawley,S., Chen,M., Ayupova,D.A., Lindhout,D.A.,
            Higbee,J., Kutach,A., Joo,W., Gao,Z., Fu,D., To,C., Mondal,K.,
            Li,B., Kekatpure,A., Wang,M., Laird,T., Horner,G., Chan,J.,
            McEntee,M., Lopez,M., Lakshminarasimhan,D., White,A., Wang,S.P.,
            Yao,J., Yie,J., Matern,H., Solloway,M., Haldankar,R., Parsons,T.,
            Tang,J., Shen,W.D., Alice Chen,Y., Tian,H. and Allan,B.B.
  TITLE     Non-homeostatic body weight regulation through a
            brainstem-restricted receptor for GDF15
  JOURNAL   Nature 550 (7675), 255-259 (2017)
   PUBMED   28953886
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24481.. PMID: 29144449]
REFERENCE   6  (bases 1 to 5478)
  AUTHORS   Kitagawa,H., Sasaki,C., Zhang,W.R., Sakai,K., Shiro,Y., Warita,H.,
            Mitsumoto,Y., Mori,T. and Abe,K.
  TITLE     Induction of glial cell line-derived neurotrophic factor receptor
            proteins in cerebral cortex and striatum after permanent middle
            cerebral artery occlusion in rats
  JOURNAL   Brain Res 834 (1-2), 190-195 (1999)
   PUBMED   10407114
REFERENCE   7  (bases 1 to 5478)
  AUTHORS   Natarajan,D., Grigoriou,M., Marcos-Gutierrez,C.V., Atkins,C. and
            Pachnis,V.
  TITLE     Multipotential progenitors of the mammalian enteric nervous system
            capable of colonising aganglionic bowel in organ culture
  JOURNAL   Development 126 (1), 157-168 (1999)
   PUBMED   9834195
REFERENCE   8  (bases 1 to 5478)
  AUTHORS   Baloh,R.H., Gorodinsky,A., Golden,J.P., Tansey,M.G., Keck,C.L.,
            Popescu,N.C., Johnson,E.M. Jr. and Milbrandt,J.
  TITLE     GFRalpha3 is an orphan member of the GDNF/neurturin/persephin
            receptor family
  JOURNAL   Proc Natl Acad Sci U S A 95 (10), 5801-5806 (1998)
   PUBMED   9576965
REFERENCE   9  (bases 1 to 5478)
  AUTHORS   Burazin,T.C. and Gundlach,A.L.
  TITLE     Up-regulation of GDNFR-alpha and c-ret mRNA in facial motor neurons
            following facial nerve injury in the rat
  JOURNAL   Brain Res Mol Brain Res 55 (2), 331-336 (1998)
   PUBMED   9582449
REFERENCE   10 (bases 1 to 5478)
  AUTHORS   Canzian,F., Ushijima,T., Nagao,M., Matera,I., Romeo,G. and
            Ceccherini,I.
  TITLE     Genetic mapping of the RET protooncogene on rat chromosome 4
  JOURNAL   Mamm Genome 6 (6), 433-435 (1995)
   PUBMED   7647468
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Oct 23, 2007 this sequence version replaced NM_012643.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (a).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.17263.1,
                                           SRR26643298.24942.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-86                JAXUCZ010000004.1  153040471-153040556 c
            87-350              JAXUCZ010000004.1  153027766-153028029 c
            351-638             JAXUCZ010000004.1  153025537-153025824 c
            639-883             JAXUCZ010000004.1  153024133-153024377 c
            884-1079            JAXUCZ010000004.1  153023194-153023389 c
            1080-1279           JAXUCZ010000004.1  153022598-153022797 c
            1280-1538           JAXUCZ010000004.1  153020535-153020793 c
            1539-1664           JAXUCZ010000004.1  153020095-153020220 c
            1665-1775           JAXUCZ010000004.1  153019386-153019496 c
            1776-1895           JAXUCZ010000004.1  153018594-153018713 c
            1896-2152           JAXUCZ010000004.1  153017780-153018036 c
            2153-2300           JAXUCZ010000004.1  153015001-153015148 c
            2301-2408           JAXUCZ010000004.1  153013399-153013506 c
            2409-2623           JAXUCZ010000004.1  153012263-153012477 c
            2624-2746           JAXUCZ010000004.1  153012047-153012169 c
            2747-2817           JAXUCZ010000004.1  153010177-153010247 c
            2818-2955           JAXUCZ010000004.1  153008931-153009068 c
            2956-3055           JAXUCZ010000004.1  153007104-153007203 c
            3056-3203           JAXUCZ010000004.1  153001892-153002039 c
            3204-5478           JAXUCZ010000004.1  152998350-153000624 c
FEATURES             Location/Qualifiers
     source          1..5478
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..5478
                     /gene="Ret"
                     /note="ret proto-oncogene"
                     /db_xref="GeneID:24716"
                     /db_xref="RGD:3556"
     exon            1..86
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     CDS             14..3361
                     /gene="Ret"
                     /EC_number="2.7.10.1"
                     /note="isoform a precursor is encoded by transcript
                     variant 1; receptor tyrosine kinase; Ret proto-oncogene
                     (multiple endocrine neoplasia MEN2A MEN2B and medullary
                     thyroid carcinoma 1 Hirschsprung disease); proto-oncogene
                     tyrosine-protein kinase receptor Ret; Ret gene for
                     receptor tyrosin"
                     /codon_start=1
                     /product="proto-oncogene tyrosine-protein kinase receptor
                     Ret isoform a precursor"
                     /protein_id="NP_036775.2"
                     /db_xref="GeneID:24716"
                     /db_xref="RGD:3556"
                     /translation="MAKARSGAAGLGLKLFLLLPLLGEAPLGLYFSRDAYWERLYVDQ
                     PAGTPLLYVHALRDAPGEVPSFRLGQYLYGVYRTRLHENDWIHIDSGTGLLYLNQSLD
                     HSSWEQLSIRNGGFPLLTVFLQVFLGSTAQREGECHWPGCARVYFSFINDTFPNCSSF
                     KARDLCTPETGVSFRIRENRPPGTFYQFRMLPVQFLCPNISVKYKLLEGDGLPFRCDP
                     DCLEVSTRWALDRELQEKYVLEAECAVAGPGANKEKVAVSFPVTVYDEDDSPPTFSGG
                     VGTASAVVEFKRKEGTVVATLQVFDADVVPASGELVRRYTSTLLSGDSWAQQTFRVEH
                     TPNETLVQSNNNSVRATMHNYKLVLNRSLSISESRVLQLVVLVNDSDFQGPGSGVLFL
                     HFNVSVLPVTLNLPMAYSFPVNRRARRYAQIGKVCVENCQEFSGVSIQYKLQPSSTNC
                     SALGVVTSTEDTSGTLYVNDTEALRRPECTELQYTVVATDRQTRRQTQASLVVTVEGT
                     YIAEEVGCPKSCAVNKRRPECEECGGLGSPTGRCEWRQGDGKGITRNFSTCSPSTRTC
                     PDGHCDALESRDINICPQDCLRGPIVGGHERGERQGIKAGYGICNCFPDEKKCFCEPE
                     DSQGPLCDELCRTVITAAVLFSFIISVLLSTFCIHRYHKHAHKPPIASAEMTFCRPAQ
                     GFPISYSSSGTRRPSLDSMENQVSVDSFKIPEDPKWEFPRKNLVLGKTLGEGEFGKVV
                     KATAFRLKGRAGYTTVAVKMLKENASQSELRDLLSEFNLLKQVNHPHVIKLYGACSQD
                     GPLLLIVEYAKYGSLRGFLRDSRKIGPAYVSSGGSRNSSSLDHPDERVLTMGDLISFA
                     WQISRGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKKSKGRI
                     PVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRME
                     RPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKSRDYLDLAASTPSDSLLY
                     DDGLSEEETPLVDCNSAPLPRSLPSTWIENKLYGMSDPNWPGESPVPLTRADGTSTGF
                     PRYANDSVYANWMVSPSAAKLMDTFDS"
     exon            87..350
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            351..638
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            639..883
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            884..1079
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1279
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1538
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1664
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            1665..1775
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..1895
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            1896..2152
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            2153..2300
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2408
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            2409..2623
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            2624..2746
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            2747..2817
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            2818..2955
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            2956..3055
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            3056..3203
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
     exon            3204..5478
                     /gene="Ret"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcgcacgg gcgatggcga aagcgaggtc cggcgccgca gggctggggc tgaagctgtt
       61 tttgctgctg ccgctactgg gagaagcccc gctgggtctc tacttctcaa gggatgctta
      121 ctgggagagg ctgtatgtgg accagccagc tggcacacct ctgctctatg tccatgccct
      181 acgggatgcc cctggagaag tgcccagctt ccgcctgggc cagtatctct atggcgtcta
      241 ccgcacgcgt ctgcatgaga atgactggat ccacatcgat tcgggcactg gcctcctcta
      301 cctcaatcag agcctggacc atagttcctg ggagcagctc agcatccgca atggcggctt
      361 ccccttgctc accgtcttcc tccaggtctt cctggggtcc acagcccaga gagagggaga
      421 gtgtcattgg ccaggctgtg cccgtgtgta cttctccttc atcaacgaca ccttcccaaa
      481 ttgtagctcc ttcaaagccc gggatctctg caccccggag acgggtgtgt ccttccgcat
      541 cagggagaac aggccccctg gcaccttcta ccagttccgc atgctacctg tgcagttcct
      601 ttgtcctaac atcagtgtga agtacaaact cttagaaggg gacggtctgc ccttccgttg
      661 tgaccccgac tgtctggagg tgagcacgcg gtgggcgctg gatcgggagc ttcaggagaa
      721 gtatgtgctg gaggctgagt gcgcagtggc aggccctgga gccaacaagg agaaggtggc
      781 cgtgtccttc ccggtgacgg tgtatgatga agacgactcc ccgcccacct tctccggagg
      841 tgtgggcacc gccagtgctg tggtggagtt taagcggaag gagggcactg tggtagccac
      901 tctgcaggtg tttgatgcag atgtggtgcc agcatctggg gagctggtga ggcggtacac
      961 aagcacacta ctctcagggg attcctgggc ccagcagacc ttccgggtgg agcacacacc
     1021 caacgagacc ttggtccagt ccaacaacaa ctccgtgcgg gcaaccatgc acaattacaa
     1081 gctggttctc aacaggagcc tgtccatctc agagagccga gtcctgcagc tagtagtcct
     1141 ggtcaatgac tcagacttcc aggggcctgg gtcaggtgtt ctcttcctcc atttcaacgt
     1201 gtctgtgctg cctgtcaccc tgaacctacc catggcctac tccttcccag tgaataggag
     1261 agcccgccgt tatgcccaga ttgggaaagt ttgcgtggag aactgccagg agttcagcgg
     1321 tgtctccatc cagtacaagc tgcagccctc cagcaccaac tgcagtgccc taggtgtggt
     1381 cacctcaaca gaagacacct cagggaccct atatgtaaat gacacggagg ccctgcggcg
     1441 acctgagtgt accgagcttc agtacacagt ggtagccact gaccggcaga cccgcaggca
     1501 gacccaggct tcgttagtcg tcacagtgga ggggacatac attgcagaag aagtgggctg
     1561 ccccaagtcc tgtgcagtaa acaagaggcg acctgagtgt gaggagtgtg gtggcctggg
     1621 ttctccaact ggcagatgtg agtggcgtca gggagatggt aaagggatca ccaggaactt
     1681 ctccacctgt tctcctagca ccaggacctg tcctgatggc cactgtgatg ctctggagag
     1741 ccgggatatc aacatttgcc cccaggactg tctccgtggc cccattgttg gcgggcatga
     1801 gcgaggggag cgccagggga ttaaagccgg ctatggcatc tgcaactgtt tccctgatga
     1861 gaagaagtgc ttctgcgagc cagaggacag ccagggccca ttgtgcgatg agctgtgccg
     1921 tacggtcatc acagccgctg tcctcttctc cttcataatc tctgtcctgc tgtccacctt
     1981 ctgcatccac cgctaccaca agcatgcgca caagccaccc atcgcgtcag ccgaaatgac
     2041 cttctgccgg ccggcccagg gcttcccaat cagctattct tcctcgggca cccgccggcc
     2101 ctcactggac tccatggaga accaggtctc tgtggactct ttcaagatcc cggaggatcc
     2161 gaagtgggaa tttcctcgga agaacttagt tcttgggaaa accctgggag aaggcgagtt
     2221 tggaaaagta gtcaaggcca cagccttccg tctgaaaggc cgggcaggat acaccacagt
     2281 ggctgtgaaa atgctgaaag aaaacgcctc ccagagtgaa ctacgagacc tgctctctga
     2341 gttcaacctt ctgaaacaag tcaaccatcc acatgtcatc aagttgtacg gggcttgcag
     2401 ccaggatggg ccacttcttc tcattgtgga gtatgcaaag tatggatccc tgcgggggtt
     2461 cctgcgggac agccgcaaga tcgggcctgc ctatgtgagc agtggaggca gccgcaattc
     2521 cagctccctg gaccacccag acgaaagggt gctgaccatg ggcgacctca tctccttcgc
     2581 ctggcagatc tcgaggggta tgcagtactt ggctgaaatg aagctcgtac atcgagactt
     2641 agctgccaga aacatcttgg tggcagaggg acggaagatg aagatctctg actttgggct
     2701 gtcccgagat gtttatgaag aagattccta tgtgaagaaa agcaagggcc ggattcccgt
     2761 caaatggatg gcaatcgagt ctctcttcga tcacatctat accactcaaa gtgatgtgtg
     2821 gtcctttgga gtgctgctat gggagattgt gaccctggga ggcaacccct accctggaat
     2881 tcctcctgaa cgactcttca accttctgaa gacaggccac aggatggaga ggccagacaa
     2941 ctgcagcgag gaaatgtacc gcctgatgct gcagtgctgg aagcaggagc cggacaagag
     3001 gccagtattt gctgacatca gcaaggatct ggagaagatg atggtcaaaa gcagagacta
     3061 cttggacctg gctgcatcca ccccttcgga ctcactgctc tatgacgatg ggctctcgga
     3121 agaggagacg cccctggtgg actgtaacag tgctcccctc ccgcgctccc tcccttccac
     3181 atggattgaa aacaaactct atggcatgtc agacccgaac tggcctggag agagtcctgt
     3241 accactcacg agagccgatg gcactagcac tgggttccca agatatgcaa atgatagtgt
     3301 atatgctaac tggatggttt caccctcagc ggcaaaatta atggacacat ttgatagtta
     3361 acatttcttt gtgaacggta atgaacctcc caagggggaa gaaacatgcc aagagcatca
     3421 agtccaccga ccactttgtg cacatcatac tggccaagac cagcctcagg tggcagactt
     3481 gttttctgta gtttgtttta gctggtttcc aaagtggttt tacttcaagt agccagtgat
     3541 cctccctcac ggtggtcctc cctcctagca catctgcccc actgggtggg tgctctgagt
     3601 ctctggttag atcccctttc ccttcagcat tgggtagcac ctctgttggt ctgctcatca
     3661 gtaactacca tgagctcttg tgttcacatg tgtggggtct gccattacaa cttggatgag
     3721 aaattgtacc tgaactgtct gattttcctg gttgattaaa aaactaccac gcaccccccc
     3781 caaatgtttt taacatgaag cacacataca aacaacatca gttgaaaaac ctggctggag
     3841 tgacctgccc ttgtttagaa tgaaagccca gcataagtct gggcagttgg atccagccag
     3901 gtccactagg gttggagggg agaagggagc ctcagggctg tccttggccc agcatatgac
     3961 atcctgaata tagatttttt ttttgagttt tttttttttt aaccatgtag ccttttctta
     4021 ggaaaacgtt gtttctgacg tggttaagcg gctcttagat ttagcacaat tgagagattg
     4081 ggtgttgccc ttgcttgtac aaggcagctc gaaagaagtg gccccataag acacagtccc
     4141 cctgttgagc ccagggcatc attctcctgt tcagcgctgc gtgacaccta cccgcagacc
     4201 agaacagggt gaagaagcag ggcatttgga gtggagcagc cttcaggccc agaattgctg
     4261 gcagcagagg ccttgagcca caaatgctgc acccccagca cagcattccg cagaacgccc
     4321 tacccacctg agagtgtgct tgacctctga tggggcaggc aggtctgcct tgttttaatc
     4381 actaccttgt cagctcatgc ccggagggaa ggacagttca tctagttgta ttagaggttt
     4441 ccctgacaac gactgaggtg agagaatgag gttttggctc ttatagagct tgtgtgaaag
     4501 gcacatggat cagctctccc catccgacat ttatgctgct gctatggtac gtgttttggt
     4561 ctcctccgtt ctgaccacga ctcccgtgta aggttcttgt ctttctgtac tgacggttgt
     4621 agcctcagac attctgcact cctctggggt tttaggggtg gctcttggaa gtttctttgg
     4681 ctgtctatgg acttgtcact tcccacgaaa aggtcacatt accaaaacac tgcctggtct
     4741 tcagacttca agcactgtga taggactttt aaatagtcgt aataaaatac tatattttat
     4801 gggcatttca caaacacagt aaaattgtga cattttatgt ggctgagaat gctcagataa
     4861 gtacaccgga tagagcctta cggagtgtgt gtaatacttg tgtgtgcaca cagccagacg
     4921 gaaagatgaa aaatgcttat ttcagcatat aatatggctt tagtttgggc catttttctt
     4981 tcagatacac tgtgataaga ttttttttaa tataaatatc tctagtcatg ggatccattt
     5041 tgtttttcag atgtgcttaa taatagtttt attaaatgca gaaatacaga taagttcaaa
     5101 ttactcaaca tgcctacaca gtattgctac agcaggttta gcttcaaggg ctgagctcca
     5161 tgtctaaata gctgacccat ctgtggggaa ttaacacttg actaataacc atttgtctgt
     5221 ctgttcctga gatacaaaag tacccatact tgttaaaagt acctatacct gttagcacta
     5281 tcagacagat ttttcatcta catatatgca gaagttacca catattaaat attactgagt
     5341 attaagtagc aatctgtcag ccactaaaat ttgtaagatc catttaagaa aggctattaa
     5401 accgtaccat gttgacttgt ttttgtaatc aaggtgacta aggaaatgat ttcagctgtg
     5461 taaataaaat tataaatc
//
