LOCUS       NM_001134546            5458 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus RAB11 binding and LisH domain, coiled-coil and
            HEAT repeat containing (Relch), mRNA.
ACCESSION   NM_001134546 XM_001056020 XM_219401
VERSION     NM_001134546.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5458)
  AUTHORS   Sobajima T, Yoshimura SI, Maeda T, Miyata H, Miyoshi E and Harada
            A.
  TITLE     The Rab11-binding protein RELCH/KIAA1468 controls intracellular
            cholesterol distribution
  JOURNAL   J Cell Biol 217 (5), 1777-1796 (2018)
   PUBMED   29514919
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474000.1.
            
            On or before Sep 4, 2008 this sequence version replaced
            XM_001056020.1, XM_219401.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132262,
                              SAMD00132266 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5458
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13p11"
     gene            1..5458
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /note="RAB11 binding and LisH domain, coiled-coil and HEAT
                     repeat containing"
                     /db_xref="GeneID:309053"
                     /db_xref="RGD:1307235"
     exon            1..765
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     CDS             240..3896
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /codon_start=1
                     /product="RAB11-binding protein RELCH"
                     /protein_id="NP_001128018.1"
                     /db_xref="GeneID:309053"
                     /db_xref="RGD:1307235"
                     /translation="MAAMAPGGGGSGSGVNPFLSDSDEDDDEVAATEDQRAGLRLGAG
                     VGLDPGSAGSLSPQDPMALGSSTRPGLPVEASAAPGALAGSGETPSRLSIDAIAAQLL
                     RDQYLLTALELHTELLESGRELPRLRDYFSNPGNFERQSGTPPGVGAPGIPGASVVGG
                     AGGREPSTTSGGGQLNRAGSISTLDSLDFARYSDDGNRETDERVAVLEFELRKAKETI
                     QALRANLTKAAEHEVPLQERKNYKSSPEIQEPIKPLEKRALNFLVNEFLLKNNYKLTS
                     ITFSDENDDQDFELWDDVGLNIPKPPDLLQLYRDFGNHQVTGKDLVDVASGVDEDELE
                     PLTPVLGNIPPTLDTPLPIENSLLVQKLEDKISLLNNEKWSLMEQIRRLESEMDILKT
                     EHFTTPAVGDSVQPSLAWPSPKDSEDSKQSPVVNSSDQDIQKAKDVHLEIPDGADSFI
                     PKEKSSDSFPTKEREELPPSSVSSKATLHFDQPNRKLSPAFHQALLSFCRMSADSRLG
                     SEVSRIADSEKSVMLMLGRCLPHIVPNVLLAKREELIPLILCTACLHPEPKERDQLLH
                     ILFNLIKRPDDEQRQMILTGCVAFARHVGPTRVEAELLPQCWEQINHKYPERRLLVAE
                     SCGALAPYLPKEIRSSLVLSMLQQMLMEDKADLVREAVIKSLGIIMGYIDDPDKYQQG
                     FELLLSALGDPSERVVSATHQVFLPAYAAWTTELGNLQSHLIPTLLSKIEKLLRDGEH
                     GLDEHKLHMYLSALQSLIPSLFALVLQNAPFSSKAKLHGEVPHIEVTRFPRPMSPLQD
                     VSTIIGSREQLAVLLQLYDYQLEHEGTTGWESLLWVVNQLLPQLIEIVGKINVTSTAC
                     VHEFSRFFWRLCRTFGKIFTNTKVKPQFQEILRLSEENIDSSAGNGVLTKATVPIYAT
                     GVLTCYIQEEDRKLLVGFLEDVMTLLSLSHAPLDSLKASFVELGANPAYHELLLTVLW
                     YGVVHTSALVRCTAARMFELLVKGVNETLVAQRVVPALITLSSDPEISVRIATIPAFG
                     TIMETVIQRELLERVKMQLASFLEDPQYQDQHSLHTEVIRTFGRVGPNAEPRFRDEFV
                     IPHLHKLALVNNLQIVDSKRLDIATHLFEAYSALSCCFISEDLMVNHFLPGLRCLRTD
                     MEHLSPEHEVILSSMIKECEQKVENKTVQEPPGSMSIAASLVSEDTKTKFLNKMGQLT
                     TSGAMLANVFQRKK"
     exon            766..855
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            856..927
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            928..983
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            984..1097
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1301
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1393
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            1394..1693
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            1694..1769
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            1770..1865
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..1978
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            1979..2069
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            2070..2141
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2282
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            2283..2447
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            2448..2595
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            2596..2752
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            2753..2876
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            2877..2925
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            2926..3005
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3006..3112
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3113..3212
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3213..3295
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3296..3359
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3360..3498
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3499..3615
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3616..3704
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3705..3775
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
     exon            3776..5458
                     /gene="Relch"
                     /gene_synonym="RGD1307235"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgagactaga gaccaggaag acgcctgcag agtcggctac cgatgcagcg gtggctgagg
       61 ctggaggtgc tgctgcatcc cggactcctg cctcccagtc tggcctagtc cctaggtgag
      121 gagaggcgcg gccagcctgg gctgcctagt tggtcagtgg ttctcaggac ccgacgggaa
      181 ttcaggctga gtgcctgtcg ggccaagtag aaaagcaccc acactcctga cagaataaga
      241 tggcggcaat ggcgccggga ggtggtggca gtggtagcgg cgtaaatcct ttcctcagcg
      301 attcggatga ggacgacgac gaggtagcag cgaccgagga ccagcgggca ggacttcggc
      361 tgggtgctgg ggtcggccta gatcctggtt ctgcaggctc gctgtcgcct caggacccca
      421 tggccctggg aagcagcacg cggccggggc tccctgtgga ggcgtcagct gctccggggg
      481 ctctggcggg cagcggagag accccttccc gattgtcaat cgatgccatc gccgctcagc
      541 tgttgcgcga tcagtacttg ctgactgccc tggagctgca caccgagctg ttggagagcg
      601 gccgcgagct accacggctg cgcgattact tctccaatcc tggcaacttc gagaggcaga
      661 gtgggacccc accaggggtg ggggcgcctg ggatccccgg cgcatccgtc gttggaggcg
      721 ctggaggtcg ggaaccgagt acgacgtcgg gcggaggaca gctcaatcga gctgggagca
      781 ttagtactct tgattcatta gactttgcaa gatattcaga tgatggtaac agggaaacag
      841 atgaaagagt ggcggtcctg gagtttgaac tacggaaagc caaggagacc attcaggccc
      901 tccgagccaa cctaacaaag gctgcagaac atgaagttcc tttacaggaa cgaaaaaatt
      961 acaaatcaag tcctgaaatt caggagccaa tcaaacctct tgaaaagaga gctctcaact
     1021 tcctagtcaa tgagtttttg ttgaagaata attacaagct tacatcaata accttttcag
     1081 atgaaaatga tgatcaggat tttgaattgt gggatgatgt aggattaaac attcccaaac
     1141 ccccagactt gttacaactt taccgagact ttggaaatca tcaagtgact gggaaagatc
     1201 ttgtggatgt ggccagtgga gtagatgaag atgaattaga gcctcttaca ccagttttag
     1261 gcaacatccc tccaaccctt gatactcccc tgcctataga gaactccttg ctagtacaga
     1321 aattagaaga taaaattagt ttattaaata atgaaaaatg gtcattgatg gagcaaatca
     1381 gaaggcttga aagtgagatg gacatcctca agactgaaca ctttaccacc ccagcagttg
     1441 gtgattctgt tcagccttcc ttggcttggc cgtccccaaa agattctgaa gacagtaaac
     1501 agagcccagt tgtaaatagt tcggaccagg atattcaaaa agccaaggat gttcatcttg
     1561 aaataccaga tggagctgat tcctttattc ctaaagagaa atcatcagat tctttcccca
     1621 caaaggaaag agaagagctg ccaccttctt ctgtatcaag taaagccacg ctccatttcg
     1681 atcagcccaa taggaaattg tcacctgctt tccaccaagc actactctct ttttgtcgaa
     1741 tgtcagcaga tagtcggtta ggatcagagg tgtctaggat tgcagacagt gaaaaaagtg
     1801 ttatgttaat gctgggacgc tgcctgccac acattgttcc taatgtgctg ttagcaaaaa
     1861 gagaggagtt gattcctctc atattgtgta cagcgtgcct acaccctgag cctaaagaaa
     1921 gagatcagct cctccatata ctcttcaact tgatcaagag gccagatgat gagcaaaggc
     1981 aaatgatact gacaggttgt gtggcatttg cacgtcatgt tggaccaaca cgtgtggagg
     2041 ctgaactttt accacagtgt tgggaacaga ttaatcacaa atatccagaa agacgactgc
     2101 tcgtggcaga gtcctgtgga gcactggcac cctaccttcc taaagaaatc cgtagttcct
     2161 tggtcctttc aatgttgcaa cagatgttaa tggaagataa ggctgatttg gtaagagaag
     2221 ctgtgattaa aagcctgggt atcattatgg gctacattga tgatcctgac aaatatcagc
     2281 agggctttga attgttactc tcggccctgg gtgatccctc agaaagagtt gttagtgcaa
     2341 cacaccaagt gtttttacca gcctatgctg cctggacaac tgaactggga aatttacagt
     2401 ctcatcttat acctacacta ctgagcaaga tcgaaaagct tctcagggac ggagagcacg
     2461 ggctggacga acacaagctc cacatgtatc tttctgcctt gcagtccttg atcccatctc
     2521 tctttgcatt agtgctacag aatgcacctt tctccagcaa agccaaactg catggtgaag
     2581 taccacacat tgaagtgact aggttccctc ggcctatgtc acctctgcaa gatgtctcta
     2641 ctattattgg aagtcgcgag caattggcag tgctgctaca actttatgat taccaactgg
     2701 aacacgaggg tacaaccggc tgggaaagtt tactctgggt tgtcaatcag ttgttgccac
     2761 agcttataga aatagtagga aaaataaatg taacctcaac tgcctgtgtt catgagttct
     2821 ccagattttt ctggcgcctt tgccggacat ttggcaaaat ttttacaaac actaaggtaa
     2881 aaccccagtt ccaggagatt ttaagactct ctgaagaaaa cattgattcc tcagcaggaa
     2941 atggggtcct cactaaagct actgtcccca tttatgcaac aggagtcctc acgtgttata
     3001 ttcaggaaga agaccgaaag ctattggtcg gcttcttgga agatgtgatg acgctgcttt
     3061 cactgtctca tgctcctctt gacagcctga aggcttcttt tgtggaactt ggtgcaaatc
     3121 cagcctatca tgagctgttg ttaactgtgt tgtggtatgg tgttgttcac acttctgcac
     3181 ttgtcaggtg tactgctgct aggatgtttg agctgttggt gaagggggtg aatgagactc
     3241 tggtagctca gagggttgtt cctgctctca ttactctctc cagtgaccct gaaatctctg
     3301 tcaggattgc tacaattcca gcatttggca ctattatgga aacggttatt cagagagagt
     3361 tgctagaaag agtgaaaatg cagttggctt ctttcctgga agaccctcag taccaagacc
     3421 agcattcttt gcatacagag gtcatcagaa catttggcag agttgggcct aatgcagaac
     3481 cccggttccg agatgaattt gttataccac atttacataa attagccttg gtgaacaact
     3541 tacaaattgt ggattccaaa agactggaca ttgcaaccca tctttttgaa gcctacagtg
     3601 cactgtcctg ttgtttcatt tcagaggatt taatggtaaa tcacttttta cctggcctca
     3661 gatgtttacg gactgacatg gagcatctct ctccagaaca tgaggttatt ttaagttcca
     3721 tgataaaaga atgtgaacaa aaagtagaaa acaagactgt ccaagagcct ccaggctcaa
     3781 tgtcaattgc tgcaagttta gtgagtgaag acacaaagac caagtttttg aacaaaatgg
     3841 gccagttgac aacatcaggt gccatgctgg ccaatgtgtt tcagaggaag aagtagaagt
     3901 gggagggcag ccgggtgaac actaagatgg acctcagtag actgctcctt gtacttgaag
     3961 tgcttatctt tttatttcct gactttatgt tcttgttata attttatcct aacctccaaa
     4021 gatatttgca ctgctttcaa ttattgctgt gtgtctgttg gtttgggaat tataactgtg
     4081 gtaatggaaa cttgatttaa tgatctgtac caagtcccta gtctatgttc ttatttttga
     4141 gaataacttt tatatataat atatatatgt atagtgaaga ggggtttttt ggttttgttt
     4201 ttttaatttt tatttttgga tgggatattc acaaatctgt attatactct aagctattac
     4261 aatggtactt aaaataatgt aaatttgaag tcattgttat aaagtaataa aagtggagat
     4321 tacttaagta tttaaattat gaaagaataa tgcagacttt ttattatttc ttaactgact
     4381 agaaagagcc accagcatta ctctgtgcct tttggacttg agtttgtgtt ctataggaat
     4441 tacatgcatt cccctcacac agtatttgag gctgctgtgg tgaatttgaa tggctgaccc
     4501 tacagtaagt agataatgat gagtcttaca acatttcaca cctctcttga aagtcctgta
     4561 agtgctgttt agcctctcaa cacttagatg cacatgatgg aattccctga ggaaaaacaa
     4621 cacttgagca cggtgaggag cagccagggt gaatttcaca gcatgtgtac tagatataaa
     4681 tgctcaaata taaatgtact gagaaaagct actaattatt catccccaag ttgaaataca
     4741 caacaaaata taatttaagt ctgaaattta acacccactt cctgtaacac attttaggat
     4801 gttttctgat tatttaaact ttgcagttta ctttttcatc ctgtcttgag aagtactaag
     4861 aagtttcgga catttggggg ttcgttcctt ttttccttct aaagtgaaag tgatgttggt
     4921 taagttatta ttggatactc accacctagt cccttaaact cagttgctgt tcccattgat
     4981 gtgttttatt tatatggtct tatggcgatg gacagtctca ccggaattgg ctggttgtct
     5041 acacagtgac acagagtgct gcctatggaa tggggtgact ggcttaaggg gtcaatgtga
     5101 ggccttaccc agttgatgca tatacgtgac tctcacattt gttgtataaa ttgatttact
     5161 ccacttggat tacatttacg tctctggaaa agctagcttt cccacacagt gaaaactcat
     5221 gaagtttata aatttgcctt gggcaaagcc atttgtttct tttacctata gtagagttgt
     5281 tgagtagtct ttcaaactgt tgggttctag gcattcctga gaaatcgaaa gtggcttcct
     5341 ttcatgtcaa aatgttgatc tgttataaat aaaaggtttt gcatacttgt tttagttgtg
     5401 tagtttgttt tcattttaaa tcactttatc catacaacag taagaaataa tttattct
//
