LOCUS       NM_001048047            1925 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus receptor accessory protein 2 (Reep2), mRNA.
ACCESSION   NM_001048047 XM_001062164
VERSION     NM_001048047.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1925)
  AUTHORS   Esteves T, Durr A, Mundwiller E, Loureiro JL, Boutry M, Gonzalez
            MA, Gauthier J, El-Hachimi KH, Depienne C, Muriel MP, Acosta
            Lebrigio RF, Gaussen M, Noreau A, Speziani F, Dionne-Laporte A,
            Deleuze JF, Dion P, Coutinho P, Rouleau GA, Zuchner S, Brice A,
            Stevanin G and Darios F.
  TITLE     Loss of association of REEP2 with membranes leads to hereditary
            spastic paraplegia
  JOURNAL   Am J Hum Genet 94 (2), 268-277 (2014)
   PUBMED   24388663
REFERENCE   2  (bases 1 to 1925)
  AUTHORS   Bjork S, Hurt CM, Ho VK and Angelotti T.
  TITLE     REEPs are membrane shaping adapter proteins that modulate specific
            g protein-coupled receptor trafficking by affecting ER cargo
            capacity
  JOURNAL   PLoS One 8 (10), e76366 (2013)
   PUBMED   24098485
  REMARK    Erratum:[PLoS One. 2013;8(12).
            doi:10.1371/annotation/6f86410c-63c3-4fcd-b1cb-9fd8d2ea95d0]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1925)
  AUTHORS   Fong KW, Leung JW, Li Y, Wang W, Feng L, Ma W, Liu D, Songyang Z
            and Chen J.
  TITLE     MTR120/KIAA1383, a novel microtubule-associated protein, promotes
            microtubule stability and ensures cytokinesis
  JOURNAL   J Cell Sci 126 (Pt 3), 825-837 (2013)
   PUBMED   23264731
REFERENCE   4  (bases 1 to 1925)
  AUTHORS   Ilegems E, Iwatsuki K, Kokrashvili Z, Benard O, Ninomiya Y and
            Margolskee RF.
  TITLE     REEP2 enhances sweet receptor function by recruitment to lipid
            rafts
  JOURNAL   J Neurosci 30 (41), 13774-13783 (2010)
   PUBMED   20943918
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC105630.1.
            
            On Sep 14, 2006 this sequence version replaced XM_001062164.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105630.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1925
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..1925
                     /gene="Reep2"
                     /note="receptor accessory protein 2"
                     /db_xref="GeneID:682105"
                     /db_xref="RGD:1586980"
     exon            1..147
                     /gene="Reep2"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..880
                     /gene="Reep2"
                     /codon_start=1
                     /product="receptor expression-enhancing protein 2"
                     /protein_id="NP_001041512.1"
                     /db_xref="GeneID:682105"
                     /db_xref="RGD:1586980"
                     /translation="MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIV
                     FAFFTTAETLTDIILSWFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKE
                     IDEYITQARDKSYETMMRVGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIR
                     DEDALPLQGPDGRLQPGPVGLLDTIEDLGDEPALSLRSSSSQADPRTETSEDDLGDKA
                     PKRTKPIKKVPKAEPPASKTLKTRPKKKSPGGGDSA"
     exon            148..220
                     /gene="Reep2"
                     /inference="alignment:Splign:2.1.0"
     exon            221..297
                     /gene="Reep2"
                     /inference="alignment:Splign:2.1.0"
     exon            298..418
                     /gene="Reep2"
                     /inference="alignment:Splign:2.1.0"
     exon            419..532
                     /gene="Reep2"
                     /inference="alignment:Splign:2.1.0"
     exon            533..680
                     /gene="Reep2"
                     /inference="alignment:Splign:2.1.0"
     exon            681..811
                     /gene="Reep2"
                     /inference="alignment:Splign:2.1.0"
     exon            812..1898
                     /gene="Reep2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caactccgcg ctccgctgac cccacggcgg ctgccgctgc taacagcagc tcctgctgcc
       61 tcagccgccg gcctcgggca gctgcatcct cacccgggct gggtcccgcc ccgccatggt
      121 gtcctggatc atctctcgcc tggtggtgct catctttggc accctgtacc cagcctattc
      181 ttcctacaag gccgtgaaga cgaaaaacgt gaaggaatat gtaaaatgga tgatgtactg
      241 gatagtcttc gccttcttca ccacagcgga gacacttacg gatataatac tgtcctggtt
      301 ccccttctac tttgagctca agattgcttt tgtgatatgg ctgctgtccc cgtacaccaa
      361 gggctccagc gttctctacc gcaagttcgt gcatccaaca ctgtccaaca aggaaaagga
      421 aatcgacgaa tacatcacgc aagcccgaga caagagctat gagaccatga tgagggtggg
      481 caagaggggc ctgaacctgg ctgccaatgc tgccgtcaca gctgctgcca agggccaggg
      541 ggtgctgtca gaaaagctcc ggagtttcag catgcaggac ctgactctca ttcgagacga
      601 ggatgcctta ccgcttcagg ggccggatgg ccgcctccaa cccggccctg tgggtctcct
      661 ggacactatt gaggacttag gagatgagcc cgccctgagt ctaaggtcaa gctcgagcca
      721 ggcagatccc cggacagaga cctcagaaga tgacctggga gacaaggcac ccaagaggac
      781 caaacccatc aagaaagtac ccaaagctga gccaccggct tccaaaacgc tcaagaccag
      841 gcccaagaag aagagtcctg gagggggtga ctcagcttga gaacttcagc ttaccctacc
      901 cctccatctg taggacaaaa caagcactga gaagagctgc agccctggcc cctctgacag
      961 tgggccacta gccccaagtg tttcagaccc gcaaacccct agatggctgt ttccagtacc
     1021 cccatcccat gaacactcct ctggagggga cttggcaaag aggagattga ggacagacgt
     1081 gatgactaag cccttgaggt ggaggctctg tggccagcac tgctcttgct gctctagtcc
     1141 cgccctgccc atccagtgcc ttgctgacca tggccatccc ttctctgagg cctgacctgt
     1201 cccccgcctc tctcctttga atgggagtag tggtcaccat ttagaaagac cagggagggg
     1261 gccttgagaa ggggaagaaa cggagcgggt ctgggaggag tgggtctggg aggagggtgt
     1321 tttcgagggc acagctctga gtggagacac gagttttcaa tatccagcat ggccttgcca
     1381 gtactgcagc tggtagggct gtgcattcta caaaagaggt gagattccga ggctgtgcgt
     1441 gctgggaagg ttgggtgtaa ggggtcgcct cctccctact tcagccctgg tctttcttcc
     1501 tctttaccca cccatgttgg tctctgaacc tcaggactca agcctttgac agaaagaggc
     1561 tccaaggggc ctctccctac ccttccaccc ttgatccctt tcacacattc atgcccacag
     1621 gttggactcc tctactccta ggctccactg cagaggccct gccaagctgg cttctttcct
     1681 ctcctgtaaa ggggacccat cccaccttgc cacggggtcc ccttcctgtg ccaagcaaac
     1741 ccctgtcaga accaacccct ggccccggtt ctgccagcct caatggggcc aagtggaacc
     1801 tgtgaaggga aagaaatgca ggagctgagg ctcccaattt catggtgccc actggacctt
     1861 ggcactggat gagccaataa acgaagctct gacacctcaa aaaaaaaaaa aaaaaaaaaa
     1921 aaaaa
//
