LOCUS       NM_001108633            3680 bp    mRNA    linear   ROD 17-JUL-2023
DEFINITION  Rattus norvegicus receptor accessory protein 1 (Reep1), mRNA.
ACCESSION   NM_001108633 XM_001069307 XM_342708
VERSION     NM_001108633.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3680)
  AUTHORS   Hashimoto Y, Shirane M, Matsuzaki F, Saita S, Ohnishi T and
            Nakayama KI.
  TITLE     Protrudin regulates endoplasmic reticulum morphology and function
            associated with the pathogenesis of hereditary spastic paraplegia
  JOURNAL   J Biol Chem 289 (19), 12946-12961 (2014)
   PUBMED   24668814
REFERENCE   2  (bases 1 to 3680)
  AUTHORS   Bjork S, Hurt CM, Ho VK and Angelotti T.
  TITLE     REEPs are membrane shaping adapter proteins that modulate specific
            g protein-coupled receptor trafficking by affecting ER cargo
            capacity
  JOURNAL   PLoS One 8 (10), e76366 (2013)
   PUBMED   24098485
  REMARK    Erratum:[PLoS One. 2013;8(12).
            doi:10.1371/annotation/6f86410c-63c3-4fcd-b1cb-9fd8d2ea95d0]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3680)
  AUTHORS   Park SH, Zhu PP, Parker RL and Blackstone C.
  TITLE     Hereditary spastic paraplegia proteins REEP1, spastin, and
            atlastin-1 coordinate microtubule interactions with the tubular ER
            network
  JOURNAL   J Clin Invest 120 (4), 1097-1110 (2010)
   PUBMED   20200447
REFERENCE   4  (bases 1 to 3680)
  AUTHORS   Saito H, Kubota M, Roberts RW, Chi Q and Matsunami H.
  TITLE     RTP family members induce functional expression of mammalian
            odorant receptors
  JOURNAL   Cell 119 (5), 679-691 (2004)
   PUBMED   15550249
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473957.1.
            
            [WARNING] On Apr 10, 2024 this sequence was replaced by
            NM_001108633.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001069307.1, XM_342708.3.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132283,
                              SAMD00132284 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3680
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q32"
     gene            1..3680
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /note="receptor accessory protein 1"
                     /db_xref="GeneID:362384"
                     /db_xref="RGD:1305230"
     exon            1..175
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..749
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /codon_start=1
                     /product="receptor expression-enhancing protein 1"
                     /protein_id="NP_001102103.1"
                     /db_xref="GeneID:362384"
                     /db_xref="RGD:1305230"
                     /translation="MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWII
                     FALFTTAETFTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKE
                     IDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIR
                     GDGAPAPSGPPPPGSGRSSGKHGQPKMSRSASESAGSSGTA"
     exon            176..248
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /inference="alignment:Splign:2.1.0"
     exon            249..325
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /inference="alignment:Splign:2.1.0"
     exon            326..446
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /inference="alignment:Splign:2.1.0"
     exon            447..560
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /inference="alignment:Splign:2.1.0"
     exon            561..738
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /inference="alignment:Splign:2.1.0"
     exon            739..3680
                     /gene="Reep1"
                     /gene_synonym="RGD1305230"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccgacgcg cgagcgcggg gccgggccgg gcgggtgcgc tcagtctggc ggcggcggtg
       61 cgcggacaga cagacgtgtc gggagcgcag caccgcccgc agcccagcaa tccgggccgc
      121 gcccgccagc cagcccgccc gccatggtgt cgtggatcat ctccaggctg gtggtgctca
      181 tatttggcac cctttatcct gcatattatt catacaaggc tgtgaagtct aaggacatta
      241 aagaatatgt caaatggatg atgtactgga tcatatttgc cctcttcacc acagcagaga
      301 cgttcacaga catcttcctt tgctggtttc cattctatta tgaactaaaa atagcatttg
      361 tagcctggct gctgtctccc tatacaaaag gatccagcct cctgtacagg aagtttgttc
      421 atcccacact gtcctcaaaa gaaaaggaaa tcgatgactg cctggtccaa gcaaaagatc
      481 gaagttatga tgccctcgtg cactttggga agcgaggctt gaatgtggcg gccaccgcag
      541 ctgtgatggc tgcctccaag ggacagggtg ccttgtcaga aagactacgg agcttcagca
      601 tgcaggacct caccaccatc aggggcgatg gtgctcctgc tccctcaggc ccccctccac
      661 cagggtctgg gaggtccagc ggcaaacacg gccagcccaa gatgtccagg agtgcttctg
      721 agagtgccgg cagctcaggc accgcctaga acccttcggt cccgcttcag gaagaaaagt
      781 acctcatcct cggccactga aaccacgtga gatgagccaa cagcaccgga tccacagatg
      841 tctctcctct gccttaaaga gctagtcact agtaactcgg aagtccgcag gctgggtgtg
      901 ctttgagtgt gcagccccac agacacggcc tttacttgct ccccccccct tctgccttta
      961 agaatttctg ttctctttcc tttttgttcc tgctggggag aggctaaagg gaaaggtggt
     1021 ggaggagggt gaactttatg tcttctgggg ttagtgattt tccacagttg gattgtcttg
     1081 tggccacagt gtttttagat atataagcac tctttccatg atgctgctga gatgtacatt
     1141 tgtaagttat ttgttgcata gtttctagtc ctgtaaatgc aaacgaagtg atctttttta
     1201 aaactccttt ggttgttctt ggtactaata cattggacta tggtgtacat atttgctgct
     1261 tttggcttaa tgttatgaac tcgcaagggc tgccagaagt tctggtaagt gagagagctg
     1321 caaaaacaaa aatgtagact aatctttcga ttctaggcaa cgtctccaac ctgcttacaa
     1381 agccagtgcc agtagggcat cacttctgca ggaaggtggc catgtgcttc cttcccatgg
     1441 ctgtgtggtt ggtagggcag agctgaggca ggagtgcagt gtttcagcaa cagggaaggt
     1501 tggtgggcat cagggagagg aaggaacaga acggcttctt cagatctgga ggtctgggtg
     1561 tcctaacagg tttgttgtgc tgtgtaccta atggcaccct tcctgccttt tggcttctga
     1621 gcccttccag gagtactgct tcaggcaggc aggcaggcag gctcgccctt acttagcatg
     1681 gatgtttgca ggatggagtc tcagctgctg gcagaattgc aagtatctca gaagcacttg
     1741 gcaagagtgt ttctccttca gggaccagtg ctgtggctga tttctccaga acgagcctgt
     1801 atctgagcac cttgttttag agtacactaa gcaagagaaa agcctagaac taggtttttg
     1861 ttacagatgt gtacagatgt gctcaaaaaa catgagaccc tcaaatctca aatgaccacc
     1921 aaaaggcagg gtctaggggg aactgaggct aagccacagg cagctgtggc tcttgctccc
     1981 tgctggcttg tgtggaagat gaacgggatg gacggacact catgtcactc catgtcttca
     2041 tggattttat acaagccagg actacactga gaattttgac aagtctctga cttagataac
     2101 attgtgttct gagggagctg ccctcttctc tgatagctga gccaaactgt agggctaatc
     2161 tatgtgcgta gagttggtgt ttcctttctg tgtaatgcat gcagaggtca caacctcttt
     2221 ggattatgtt tgttcaccgc tatgccctga aggctagaga aatcgcgttg tgtaccacat
     2281 agaactgtca actgattgca aacaggctca atgacaaacc gctctggtac tgagctatgc
     2341 aaacatgcat tgagagactg ctacattagc tggggcttgg ccatttcaca aagcgtttca
     2401 gttggagttc attgctacca gatacaccta gtggattttc caaagatgat tttgtatttt
     2461 agaacccacc ctcgggaact aacccaagag ctgatgactg aggacaaata gtctgcctgt
     2521 gccccatacc catctgaacc cattaggaaa agcatctgcc ctcttcaagc tcacccaaca
     2581 gctcctcaca agagaaatga taccctctaa aatgtacaac catgtcagtt aggtgtatcc
     2641 aggatgaatc cagagacaca ggtgcagaaa agactgagag aagaagcttt gaacctcccc
     2701 cccccgcccc ccagaatact aactggctct agggccagag tttaagtcct agtacatttt
     2761 caccgtttta caacaggaag tcataaccat ctaggctcca aggttgtact cagccatgcc
     2821 aaaacccagt cggaagcact cctctcagat atgctgtatt acttcttgct caagatttaa
     2881 aatataaagg tatctaaatt gtcgtctcat tgtaagtgta actatttttc cttcaagtgg
     2941 tgactaagaa gttgactaag tttcttctct taatgacact cactgtacag ccaaacacag
     3001 ctgtcttatt tcttaagaac tgtgtttatt tttccaacaa gctgtgtgtt tgtatgtaga
     3061 ctgacatgat gtgaatgccc ctgtacatgt agaggtgtgg tgctctgtct acacaagata
     3121 aatgaatgtt tctagtttgc tgacttaaga cacgggctgt tgacaaattg ctagcttgaa
     3181 ggtctacttg tctcggcttt gagttacagt ccatggagca catgccccat ttctgaagag
     3241 gtgcggtttc acgctcatca actggagatt tagtcagaat gcctcctggc tttgtgtgaa
     3301 tagcttgctc actttgctgg cctttgatat atgtattctc tgtggtaaac tgtccgtgtg
     3361 tttgtattaa gagtgcttgt caatcacaac catcacatag ccatcccggt tcttcatctt
     3421 gcacagtatt tgaagtatta caagtggtgg aagatgtgct tcatcctccg acagtgcacg
     3481 ctgggagagc tgatgttgcg gatcgtgact gcgcatttcc tccagcttat ttctgaggtc
     3541 tctctaggat ggaaataatt aatagtacac tggactgcgt gtctaaggga tgtaaagtgc
     3601 agtgttccgg aggctgaagc tctgctgttt tgttataatg cctgataaac atcttgaata
     3661 aagtcttaac atttttcttt
//
