LOCUS       NM_001168593            1158 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus retinol dehydrogenase 8 (Rdh8), mRNA.
ACCESSION   NM_001168593 XM_001076291 XM_001077102
VERSION     NM_001168593.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1158)
  AUTHORS   Kiser,P.D., Golczak,M., Maeda,A. and Palczewski,K.
  TITLE     Key enzymes of the retinoid (visual) cycle in vertebrate retina
  JOURNAL   Biochim Biophys Acta 1821 (1), 137-151 (2012)
   PUBMED   21447403
  REMARK    Review article
REFERENCE   2  (bases 1 to 1158)
  AUTHORS   Maeda,A., Maeda,T., Imanishi,Y., Kuksa,V., Alekseev,A.,
            Bronson,J.D., Zhang,H., Zhu,L., Sun,W., Saperstein,D.A., Rieke,F.,
            Baehr,W. and Palczewski,K.
  TITLE     Role of photoreceptor-specific retinol dehydrogenase in the
            retinoid cycle in vivo
  JOURNAL   J Biol Chem 280 (19), 18822-18832 (2005)
   PUBMED   15755727
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On or before Dec 13, 2009 this sequence version replaced
            XM_001077102.1, XM_001076291.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-103               JAXUCZ010000008.1  27629380-27629482
            104-265             JAXUCZ010000008.1  27633755-27633916
            266-445             JAXUCZ010000008.1  27634457-27634636
            446-539             JAXUCZ010000008.1  27635431-27635524
            540-723             JAXUCZ010000008.1  27635959-27636142
            724-1158            JAXUCZ010000008.1  27636217-27636651
FEATURES             Location/Qualifiers
     source          1..1158
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q13"
     gene            1..1158
                     /gene="Rdh8"
                     /note="retinol dehydrogenase 8"
                     /db_xref="GeneID:690953"
                     /db_xref="RGD:1589829"
     CDS             1..939
                     /gene="Rdh8"
                     /EC_number="1.1.1.300"
                     /note="retinol dehydrogenase 8 (all-trans)"
                     /codon_start=1
                     /product="retinol dehydrogenase 8"
                     /protein_id="NP_001162065.1"
                     /db_xref="GeneID:690953"
                     /db_xref="RGD:1589829"
                     /translation="MASQPQRVLISGCSSGIGLELAVQLAHDPRQRYQVVATMRDLGK
                     KEPLEAAAGEALGKTLSVAQLDVCSDESVTNCLSHIEGGQVDILVNNAGVGLVGPLED
                     LSLATMQNVFNTNFFGAVRLVKAVLPGMKRRRQGHIVVVSSVMGLQGVMFNDVYAASK
                     FALEGFFESLAIQLRQFNIFISMVEPGPVITDFEGKLLAQVSKTEFPDTDPETLGYFR
                     DLYLPASRELFRSVGQSPRDVAQVIAKVIGSTRPPLRRQTNARYFPLTALKALDPSGS
                     LYVRTTHRLLFRWPHLLSLGLRCLACGCLPTRVGPT"
     exon            1..103
                     /gene="Rdh8"
                     /inference="alignment:Splign:2.1.0"
     exon            104..265
                     /gene="Rdh8"
                     /inference="alignment:Splign:2.1.0"
     exon            266..445
                     /gene="Rdh8"
                     /inference="alignment:Splign:2.1.0"
     exon            446..539
                     /gene="Rdh8"
                     /inference="alignment:Splign:2.1.0"
     exon            540..723
                     /gene="Rdh8"
                     /inference="alignment:Splign:2.1.0"
     exon            724..1158
                     /gene="Rdh8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcctctc agcctcagag ggtgctcatc tctggctgct cttcagggat cggccttgaa
       61 ctcgctgttc agctggctca tgaccccaga caacgttacc aggtggtggc caccatgagg
      121 gacttgggga agaaggagcc attggaggca gctgctggag aggctcttgg aaagaccctc
      181 agcgtggccc agctggacgt gtgcagtgat gagtcagtga ctaactgtct cagccacatc
      241 gagggaggac aagtggacat actggtgaac aacgcaggag taggccttgt ggggcccctg
      301 gaggacctca gcctagccac catgcagaat gtgttcaaca ccaacttttt tggggctgtc
      361 cgtctggtca aagctgtgct tccaggcatg aagaggaggc gccagggtca catcgtggtg
      421 gtcagcagtg ttatggggct ccagggcgtc atgttcaatg atgtctatgc agcctccaag
      481 tttgccctgg aagggttctt cgagagcctc gcgatccagc tgcgacaatt caatatcttc
      541 atctcaatgg tggagccagg cccagtcatc actgactttg aaggaaaact cctggctcag
      601 gtttccaaga cggagttccc agacactgac ccggaaaccc tgggctactt ccgggacttg
      661 tacctcccag cctccaggga gctcttccgc tctgtgggac agagcccgcg ggatgtggcc
      721 caggtcattg ccaaggtcat cggttccacc agacccccac tccgcagaca gaccaacgct
      781 cgctacttcc cactgacggc gcttaaggcc ctggacccct ctggaagcct gtatgtgaga
      841 actacccaca ggctcctttt tcgctggcct caccttctca gccttggtct ccgatgtctg
      901 gcttgtggct gcctcccaac acgtgtgggg cctacatgaa cagggcagaa ctgacccgtc
      961 ccacccggaa cagcagggct ctgcttggaa accgtacaga cacattccca ttcaggcccg
     1021 tgggggaaaa attttttttt acaaagtctt actatgtagc cctggaactt actatgtaga
     1081 ccaggctggc ctccaactca caggcgtcga gctgactcag ccttcctagt gctgaaatta
     1141 aaggcctgta ccaccaca
//
