LOCUS       NM_133543               1174 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus retinol dehydrogenase 7 (Rdh7), mRNA.
ACCESSION   NM_133543 XM_346796
VERSION     NM_133543.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1174)
  AUTHORS   Napoli,J.L.
  TITLE     Physiological insights into all-trans-retinoic acid biosynthesis
  JOURNAL   Biochim Biophys Acta 1821 (1), 152-167 (2012)
   PUBMED   21621639
  REMARK    Review article
REFERENCE   2  (bases 1 to 1174)
  AUTHORS   Chai,X., Zhai,Y. and Napoli,J.L.
  TITLE     Cloning of a rat cDNA encoding retinol dehydrogenase isozyme type
            III
  JOURNAL   Gene 169 (2), 219-222 (1996)
   PUBMED   8647450
REFERENCE   3  (bases 1 to 1174)
  AUTHORS   Chai,X., Boerman,M.H., Zhai,Y. and Napoli,J.L.
  TITLE     Cloning of a cDNA for liver microsomal retinol dehydrogenase. A
            tissue-specific, short-chain alcohol dehydrogenase
  JOURNAL   J Biol Chem 270 (8), 3900-3904 (1995)
   PUBMED   7876135
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088090.1.
            
            On or before Feb 5, 2005 this sequence version replaced
            XM_346796.1, NM_133543.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088090.1, BC098650.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..1174
                     /gene="Rdh7"
                     /gene_synonym="Rdh3; RGD1307178; RoDH(III)"
                     /note="retinol dehydrogenase 7"
                     /db_xref="GeneID:360420"
                     /db_xref="RGD:631370"
     exon            1..398
                     /gene="Rdh7"
                     /gene_synonym="Rdh3; RGD1307178; RoDH(III)"
                     /inference="alignment:Splign:2.1.0"
     CDS             86..1039
                     /gene="Rdh7"
                     /gene_synonym="Rdh3; RGD1307178; RoDH(III)"
                     /EC_number="1.1.1.105"
                     /note="retinol dehydrogenase type III; retinol
                     dehydrogenase 3; RODH I; RODH III; hypothetical gene
                     supported by NM_133543"
                     /codon_start=1
                     /product="retinol dehydrogenase 7"
                     /protein_id="NP_598227.3"
                     /db_xref="GeneID:360420"
                     /db_xref="RGD:631370"
                     /translation="MWLYLLALVGLWNLLRLFRERKVVSHLQDKYVFITGCDSGFGNL
                     LARQLDRRGMRVLAACLTEKGAEQLRSKTSDRLETVILDVTKTESIVAATQWVKERVG
                     NRGLWGLVNNAGISVPMGPNEWMRKKDFASVLDVNLLGVIEVTLNMLPLVRKARGRVV
                     NIASTMGRMSLLGGGYCISKYGVEAFSDSLRRELTYFGVKVAIIEPGGFKTNVTNMER
                     LSDNLKKLWDQATEEVKEIYGEKFRDSYMKAMESLVNMCSGDLSLVTDCMEHALTSCH
                     PRTRYSAGWDAKFFYLPMSYLPTFLSDAVIYWGSVKPARAL"
     exon            399..657
                     /gene="Rdh7"
                     /gene_synonym="Rdh3; RGD1307178; RoDH(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            658..821
                     /gene="Rdh7"
                     /gene_synonym="Rdh3; RGD1307178; RoDH(III)"
                     /inference="alignment:Splign:2.1.0"
     exon            822..1152
                     /gene="Rdh7"
                     /gene_synonym="Rdh3; RGD1307178; RoDH(III)"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccctgaagcc tacaccatcc tgcgtgagca gatgcccgtc tcattttgac tcagagtctg
       61 tccctctgct tgtcttctac aagccatgtg gctctacctg ctggcactgg tgggcctgtg
      121 gaacctcctg cgcttgttca gggagaggaa ggtggtgagc catctccaag acaagtatgt
      181 cttcatcacg ggctgtgact caggctttgg gaacctgctg gccagacagc tggacaggag
      241 aggcatgagg gtgctggctg catgtctgac tgagaaggga gccgagcagc tgaggagcaa
      301 gacatcggac aggctggaga cagtgatcct tgatgtcacc aagacagaga gtattgtggc
      361 agccactcag tgggtgaagg agcgagttgg gaacagagga ctctggggcc tggtcaacaa
      421 tgctggcatc tctgtcccca tgggtcccaa tgagtggatg agaaaaaagg actttgcaag
      481 tgtgctggat gtgaacctgt tgggcgtcat cgaggtgact ctgaacatgc tgcccttagt
      541 aaggaaggca aggggccgcg tggtcaacat cgccagcacc atgggccgaa tgtctctcct
      601 tggtggtggt tactgcatct ccaagtatgg tgtagaggcc ttctcagact ccctcaggag
      661 ggagctcacc tactttgggg tgaaggtggc tattatagag cctggtgggt tcaagaccaa
      721 tgtcactaat atggagaggc tatcagacaa cctgaagaag ctgtgggacc aggccactga
      781 ggaggtcaag gagatctacg gcgagaagtt tcgggactcc tatatgaaag caatggagtc
      841 actggtgaac atgtgctcag gggacctgtc tctggtaacc gactgcatgg agcacgccct
      901 gacttcctgt caccctcgca cccggtactc agctggttgg gatgccaagt tcttctacct
      961 ccccatgagc taccttccca cctttctttc ggatgccgta atctactggg gctctgtaaa
     1021 gcctgcccga gccctgtgaa tctgcacatg tgtgcagact tggggaagta aggcgggtgg
     1081 agggagataa caatgtgggg tccattgttc accatactca ttaaaataat tctgcttccg
     1141 tactactcaa aaaaaaaaaa aaaaaaaaaa aaaa
//
