LOCUS       NM_001100585            1443 bp    mRNA    linear   ROD 08-DEC-2024
DEFINITION  Rattus norvegicus Ras converting CAAX endopeptidase 1 (Rce1), mRNA.
ACCESSION   NM_001100585 XM_001071802 XM_219685
VERSION     NM_001100585.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1443)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   2  (bases 1 to 1443)
  AUTHORS   Burrows,J.F., Kelvin,A.A., McFarlane,C., Burden,R.E.,
            McGrattan,M.J., De la Vega,M., Govender,U., Quinn,D.J., Dib,K.,
            Gadina,M., Scott,C.J. and Johnston,J.A.
  TITLE     USP17 regulates Ras activation and cell proliferation by blocking
            RCE1 activity
  JOURNAL   J Biol Chem 284 (14), 9587-9595 (2009)
   PUBMED   19188362
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC158593.1 and BC087629.1.
            
            On or before May 31, 2008 this sequence version replaced
            XM_001071802.1, XM_219685.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087629.1, CK596437.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-13                BC158593.1         1-13
            14-1443             BC087629.1         1-1430
FEATURES             Location/Qualifiers
     source          1..1443
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..1443
                     /gene="Rce1"
                     /note="Ras converting CAAX endopeptidase 1"
                     /db_xref="GeneID:309153"
                     /db_xref="RGD:1309261"
     exon            1..196
                     /gene="Rce1"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..1001
                     /gene="Rce1"
                     /EC_number="3.4.26.1"
                     /note="FACE-2; prenyl protein-specific endoprotease 2;
                     farnesylated proteins-converting enzyme 2; RCE1 homolog,
                     prenyl protein peptidase; RCE1 homolog, prenyl protein
                     protease"
                     /codon_start=1
                     /product="CAAX prenyl protease 2"
                     /protein_id="NP_001094055.1"
                     /db_xref="GeneID:309153"
                     /db_xref="RGD:1309261"
                     /translation="MAALGGDGLRLLSVSRPERQPESAALSSPGPGLCCWVSVFSCFS
                     LACSYVGSLYVWKSELPRDHPAVIKRRFTSVLVVSSLSPLCVLLWRELTGIQPGTSLL
                     TLMGFRLEGIFPAALLPLLLTMILFLGPLMQLCMDCPCDLTDGLKVVLAPRSWARRLT
                     DMRWLRNQVIAPLTEELVFRACMLPMLAPCTGLGPAVFTCPLFFGVAHFHHIIEQLRF
                     RQSSVGSIFLSAAFQFSYTAVFGAYTAFLFIRTGHLIGPVLCHSFCNYMGFPAVCAAL
                     EHPQKWPLLAGYALGVGLFLLLLQPLTDPKLYGSLPLCMLLERTGASETLLCS"
     exon            197..299
                     /gene="Rce1"
                     /inference="alignment:Splign:2.1.0"
     exon            300..383
                     /gene="Rce1"
                     /inference="alignment:Splign:2.1.0"
     exon            384..462
                     /gene="Rce1"
                     /inference="alignment:Splign:2.1.0"
     exon            463..630
                     /gene="Rce1"
                     /inference="alignment:Splign:2.1.0"
     exon            631..702
                     /gene="Rce1"
                     /inference="alignment:Splign:2.1.0"
     exon            703..765
                     /gene="Rce1"
                     /inference="alignment:Splign:2.1.0"
     exon            766..1415
                     /gene="Rce1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctgggcgt gatggcggcg ctgggcgggg acgggctgcg tttactgtcg gtatcgcggc
       61 cagagcggca gcccgagtca gccgcgttga gcagcccggg cccagggctg tgctgctggg
      121 tgtctgtgtt ctcctgcttc agcctcgcct gctcctacgt gggcagcctc tacgtgtgga
      181 agagcgagct gcccagggac caccccgctg ttatcaagcg gcgtttcacc agtgtcctgg
      241 tagtatcgag cttgtcccca ctttgcgtgc tgctctggag ggaactcact ggcatccagc
      301 caggcacatc actgcttacc ttgatgggct tcaggctgga gggcattttt ccagcagctc
      361 tgctgcccct gctgctaact atgatccttt tcctgggtcc actgatgcag ctctgtatgg
      421 attgcccgtg tgacctgaca gatgggctga aggttgtcct ggcccctcgt tcttgggccc
      481 gccgcctcac agacatgcgc tggctacgaa accaagttat agcacccttg acagaggagc
      541 tggtgttccg ggcttgtatg ctgcccatgc tagcaccatg cacaggtctg ggccctgctg
      601 tgttcacctg cccactgttt tttggagtcg cccattttca ccacattatt gagcagctgc
      661 gcttccgcca aagcagtgtg ggaagtatct tcttgtctgc agcgttccag ttctcctaca
      721 ccgctgtctt cggtgcttat acggctttcc tcttcatccg cacaggacac ctgatagggc
      781 cggttctctg ccactccttc tgcaactaca tgggcttccc tgctgtgtgt gcagccctgg
      841 agcatccaca gaagtggcca ctgctggcgg gctatgccct tggtgtggga ctcttcctgc
      901 ttctgcttca acccctgaca gaccccaagc tctatggcag ccttcctctt tgtatgcttt
      961 tggaacgaac gggggcctca gagaccctac tgtgctcctg accatcactc ttgtgtgaac
     1021 tctgatgggc tctccagccc cttcttatca atactgcgag agaggggctg gctggggtcc
     1081 ccgagatctc aggaattttt gtaggggatt gaagccagag ctagttgaat cccagggacc
     1141 aagagaaagg agcagatatc caaagggtgc agcccctcgt gatggggcgg atgagcagca
     1201 actggaagtg aggggacaag ggcaaatcct aggagctgtg cactccctct ttggattgat
     1261 gcttctctag ctcctttgcg tctccccttc tcccttgaaa agctgctggg gtgggtttat
     1321 ttatcaaacc cctcctccca acttcccagg gttttctcat tgtctttttg catcaagact
     1381 ttgtattggg atattaaaga gatttaactt gggtaaaaaa aaaaaaaaaa aaaaaaaaaa
     1441 aaa
//
