LOCUS       NM_001128189            1584 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus regulator of chromosome condensation 1 (Rcc1),
            mRNA.
ACCESSION   NM_001128189 XM_001063647
VERSION     NM_001128189.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1584)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 1584)
  AUTHORS   England,J.R., Huang,J., Jennings,M.J., Makde,R.D. and Tan,S.
  TITLE     RCC1 uses a conformationally diverse loop region to interact with
            the nucleosome: a model for the RCC1-nucleosome complex
  JOURNAL   J Mol Biol 398 (4), 518-529 (2010)
   PUBMED   20347844
REFERENCE   3  (bases 1 to 1584)
  AUTHORS   Schulze,H., Dose,M., Korpal,M., Meyer,I., Italiano,J.E. Jr. and
            Shivdasani,R.A.
  TITLE     RanBP10 is a cytoplasmic guanine nucleotide exchange factor that
            modulates noncentrosomal microtubules
  JOURNAL   J Biol Chem 283 (20), 14109-14119 (2008)
   PUBMED   18347012
REFERENCE   4  (bases 1 to 1584)
  AUTHORS   Chen,T., Muratore,T.L., Schaner-Tooley,C.E., Shabanowitz,J.,
            Hunt,D.F. and Macara,I.G.
  TITLE     N-terminal alpha-methylation of RCC1 is necessary for stable
            chromatin association and normal mitosis
  JOURNAL   Nat Cell Biol 9 (5), 596-603 (2007)
   PUBMED   17435751
REFERENCE   5  (bases 1 to 1584)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   6  (bases 1 to 1584)
  AUTHORS   Nemergut,M.E., Mizzen,C.A., Stukenberg,T., Allis,C.D. and
            Macara,I.G.
  TITLE     Chromatin docking and exchange activity enhancement of RCC1 by
            histones H2A and H2B
  JOURNAL   Science 292 (5521), 1540-1543 (2001)
   PUBMED   11375490
REFERENCE   7  (bases 1 to 1584)
  AUTHORS   Renault,L., Kuhlmann,J., Henkel,A. and Wittinghofer,A.
  TITLE     Structural basis for guanine nucleotide exchange on Ran by the
            regulator of chromosome condensation (RCC1)
  JOURNAL   Cell 105 (2), 245-255 (2001)
   PUBMED   11336674
REFERENCE   8  (bases 1 to 1584)
  AUTHORS   Bischoff,F.R. and Ponstingl,H.
  TITLE     Catalysis of guanine nucleotide exchange on Ran by the mitotic
            regulator RCC1
  JOURNAL   Nature 354 (6348), 80-82 (1991)
   PUBMED   1944575
REFERENCE   9  (bases 1 to 1584)
  AUTHORS   Ohtsubo,M., Okazaki,H. and Nishimoto,T.
  TITLE     The RCC1 protein, a regulator for the onset of chromosome
            condensation locates in the nucleus and binds to DNA
  JOURNAL   J Cell Biol 109 (4 Pt 1), 1389-1397 (1989)
   PUBMED   2677018
REFERENCE   10 (bases 1 to 1584)
  AUTHORS   Ohtsubo,M., Kai,R., Furuno,N., Sekiguchi,T., Sekiguchi,M.,
            Hayashida,H., Kuma,K., Miyata,T., Fukushige,S., Murotsu,T. et al.
  TITLE     Isolation and characterization of the active cDNA of the human cell
            cycle gene (RCC1) involved in the regulation of onset of chromosome
            condensation
  JOURNAL   Genes Dev 1 (6), 585-593 (1987)
   PUBMED   3678831
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC160834.1.
            
            On Jun 15, 2008 this sequence version replaced NM_001128189.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC160834.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1584
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1584
                     /gene="Rcc1"
                     /note="regulator of chromosome condensation 1"
                     /db_xref="GeneID:682908"
                     /db_xref="RGD:1592835"
     exon            1..33
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            34..153
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            154..235
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             163..1428
                     /gene="Rcc1"
                     /codon_start=1
                     /product="regulator of chromosome condensation"
                     /protein_id="NP_001121661.1"
                     /db_xref="GeneID:682908"
                     /db_xref="RGD:1592835"
                     /translation="MPPKRIAKRRSPPEDAIPKSKKVKVSHRSHNTEPGLVLTLGQGD
                     VGQLGLGESVLERKKPALVPLLQDVVQAEAGGMHTVCLSQSGQVYSFGCNDEGALGRD
                     TSVEGSEMVPGKVELQEKVVQVSAGDSHTAALTEDGRVFLWGSFRDNNGVIGLLEPMK
                     KSMVPVQVQLDTQVVKVASGNDHLVMLTTDGDLYTLGCGEQGQLGRVPELFANRGGRQ
                     GLERLLVPRCVLLKSRGTRGRVRFQDAFCGAYFTFAISREGHVYGFGLSNYHQLGTPG
                     TGSCFIPQNLTSFKNSTKSWVGFSGGQHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEE
                     KSIPTLISRLPVVSSVACGASVGYAVSKDGRVFAWGMGTNYQLGTGQEDDAWSPVEMT
                     GKQLENREVLTVSSGGQHTVLLVKDKTQS"
     exon            236..423
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            424..603
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            604..700
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            701..823
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            824..979
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1099
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1100..1252
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1555
                     /gene="Rcc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caatgatggg ggcattgagg gggcacctcg aagccatgtg agtgaataag atcttggaga
       61 aagacattgg agtttccagg gtgaagcttg gagaaacttc accgtctacc atccaggaga
      121 ggtcatgatg gaggcagaag taaacctgaa aaggacagga agatgccacc caagcgcata
      181 gctaagagaa ggtcaccccc agaagatgct atccccaaaa gcaagaaggt gaaagtctca
      241 cacaggtccc acaacacaga accaggcttg gtgctgacat tgggccaggg cgacgtgggc
      301 cagctggggc tgggtgagag tgtgctggag aggaagaagc cggccttggt accccttcta
      361 caggatgttg tgcaggccga ggccgggggc atgcacactg tgtgtctgag ccaaagtggc
      421 caggtctact cctttggctg caatgacgag ggtgccctgg gaagggacac ctcagtcgag
      481 ggctccgaga tggtccccgg gaaagtggaa ctacaagaga aagtggtgca agtgtcagcg
      541 ggagacagtc acacagcagc tctcactgaa gacggccgag tcttcctctg gggctctttc
      601 cgggacaata atggtgtgat cgggttgttg gagcccatga agaagagcat ggtgcctgtg
      661 caggtgcagc tggacacgca ggtggtaaag gtagcctcgg ggaacgacca cttggtgatg
      721 ctcacaactg atggagatct ctacaccttg ggctgtgggg agcaaggtca gctgggccgt
      781 gtgcctgagt tatttgccaa ccgaggtggc cgtcagggcc ttgagcgact cctagtcccc
      841 aggtgtgtgc tgctgaagtc ccggggaacg cggggccgcg tgcggttcca ggatgccttc
      901 tgtggcgcct atttcacctt cgccatctcc cgtgagggcc atgtgtatgg ctttggcctc
      961 tccaactatc accagctcgg aactccaggc actgggtctt gcttcattcc tcaaaacttg
     1021 acatccttca agaattccac caagtcctgg gtgggcttct ctggtggcca gcatcataca
     1081 gtctgcatgg attcagaagg aaaagcatac agcctgggcc gggctgagta cgggcggctg
     1141 ggccttgggg agggtgctga ggagaagagc atacccaccc tcatttcccg gctaccggtg
     1201 gtctcctcag tggcctgtgg ggcttcagtg gggtacgctg tgtccaagga tggtcgtgtt
     1261 tttgcctggg gcatgggcac caactaccaa ctgggcaccg ggcaggagga cgatgcctgg
     1321 agcccggtgg agatgactgg caaacagctg gagaaccgtg aggtgttaac ggtgtccagt
     1381 gggggccagc acacagtctt actagttaag gacaagaccc aaagctgatg acatctttgt
     1441 gggcctggct tctggcccca acccagcttc acagaacagg agcggccagc tacagattcc
     1501 agaaggcccc tccccacccc tgagcagaaa tcatctcctg tctttcccat caccaaaaaa
     1561 aaaaaaaaaa aaaaaaaaaa aaaa
//
