LOCUS       NM_001107875            5042 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus rabenosyn, RAB effector (Rbsn), mRNA.
ACCESSION   NM_001107875 XM_001076679 XM_232195
VERSION     NM_001107875.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5042)
  AUTHORS   Mishra A, Eathiraj S, Corvera S and Lambright DG.
  TITLE     Structural basis for Rab GTPase recognition and endosome tethering
            by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)
  JOURNAL   Proc Natl Acad Sci U S A 107 (24), 10866-10871 (2010)
   PUBMED   20534488
REFERENCE   2  (bases 1 to 5042)
  AUTHORS   Naslavsky N, McKenzie J, Altan-Bonnet N, Sheff D and Caplan S.
  TITLE     EHD3 regulates early-endosome-to-Golgi transport and preserves
            Golgi morphology
  JOURNAL   J Cell Sci 122 (Pt 3), 389-400 (2009)
   PUBMED   19139087
REFERENCE   3  (bases 1 to 5042)
  AUTHORS   Kang D, Oh S, Ahn SM, Lee BH and Moon MH.
  TITLE     Proteomic analysis of exosomes from human neural stem cells by flow
            field-flow fractionation and nanoflow liquid chromatography-tandem
            mass spectrometry
  JOURNAL   J Proteome Res 7 (8), 3475-3480 (2008)
   PUBMED   18570454
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473957.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_232195.4, XM_001076679.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5042
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..5042
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /note="rabenosyn, RAB effector"
                     /db_xref="GeneID:312562"
                     /db_xref="RGD:1305397"
     exon            1..166
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            167..480
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     CDS             336..2687
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /note="zinc finger, FYVE domain containing 20"
                     /codon_start=1
                     /product="rabenosyn-5"
                     /protein_id="NP_001101345.1"
                     /db_xref="GeneID:312562"
                     /db_xref="RGD:1305397"
                     /translation="MASLDDAGEVREGFLCPLCLKDLQSFYQLQSHYEEEHSGDRDVK
                     GQIKNLVQKARKAKNKLLKREGDDRVEPGTQGYESFSYGGVDPYMWEPQELGAMRSHL
                     SDFKKHRAARIDHYVIEVNKLIIRLEKLTAFDRTNTETSKIRAIEKSVVPWVNDQDVP
                     FCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELIGLPLANKLTSASKDSLSTHTSPSQS
                     PNSVHGSRRGSISSMSSVSSVLDEKDDERIRCCTHCKDTLLKREQQMDEKEHTPDIVK
                     LYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHANDLRVEVQKVYELIDALSKK
                     ILTLGLNQDPSPHPNTLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKQDL
                     EQKRTMERQAALESRRKLEERQSGLASHTANGDMRSLQGIPAPLRKAEGWLPLSEGQV
                     QSEDPDPLLQQIYNITSFIRQAKAAGRTDEVRTLQENLRQLQDEYDQQQTEKAIELSR
                     RQAEEEELQREQLQMLRQRELEREEEQFLAASLQTRTRVLELREVLPFQLEPIRGPHT
                     DLAYSLDEDSSPVQSSTAPDILSPGSALAPIHVWSGSPALSQELLLQSTISQPSSKTS
                     LNPFDEEDLSSPIEGAVSPAAVEAFLGPPAAVTKEYNPFEEDAEEEEVAELGAGNPFT
                     DPDSPAPNPFDEDDHPRSASPAAPGNPFEECPCTNPFEVDSDSGMEAEEHIEEELLLQ
                     QIDNIKAYIFDAKQCGRMDEVEVLTENLRELKCTLAKQKGAPN"
     exon            481..621
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            622..722
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            723..768
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            769..930
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1172
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1243
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1330
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            1331..1433
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            1434..1538
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..5042
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccaccgatg gctatggctg ccgcgggtct ctgaggaatc tcgaaggccg ggagtcggga
       61 gctggagctg gagagtaggc tgccggctga ctgtcggaag tcgcagggag agaggaaggg
      121 tgttggcttg ctcggagccg ccaccgagag cgcagcggtg gctgagattc cttctgctga
      181 agagaggaaa gctcatccaa ggccacaatg tcacttccca gttatccaag agctgcttgc
      241 tcaagctaac actgccagaa tcctgctccc ttgggaggag tcaagctgac ttggcatgag
      301 gtccctgcct tcctggggtt gagagaagta caactatggc atctttggat gacgcagggg
      361 aagtgaggga aggcttcctg tgccctctgt gcctcaagga ccttcagtct ttctatcaac
      421 ttcagtcaca ttatgaggaa gaacactcag gagatcgtga tgtcaaaggg caaattaaaa
      481 atcttgttca gaaggctagg aaagcaaaga acaagttgtt gaaacgagaa ggagatgatc
      541 gtgtggagcc agggacccaa ggatacgaat cattcagcta tggaggggtt gatccttaca
      601 tgtgggaacc tcaagagctt ggtgctatga gaagccatct ttctgatttt aaaaaacatc
      661 gtgctgcaag gattgaccac tatgttattg aagtcaataa attaataatc aggttggaaa
      721 agcttaccgc atttgacaga acaaatactg agacctcaaa gattagagca atagaaaagt
      781 ctgtggtgcc ttgggtcaat gaccaggatg ttccattctg tccagactgt gggaataagt
      841 tcagcatccg gaaccgccgt caccactgcc gcctctgtgg gtctatcatg tgcaagaagt
      901 gtatggagct cattggcctg cccttggcaa ataagctcac cagtgccagc aaggactccc
      961 tgagcaccca caccagcccc agccagtcac ctaacagtgt ccatggctcc cgccgaggca
     1021 gcatcagtag catgagcagt gtcagctcag tcctggacga gaaggatgat gagcgcatcc
     1081 gctgctgcac gcactgcaag gacacgctgc tcaagagaga gcagcagatg gatgagaagg
     1141 agcacacgcc tgacatcgtg aagctctacg agaaacttcg actttgcatg gagaaagttg
     1201 atcagaaagc tcctgaatac atcaggatgg cagcatcatt aaatgctggg gagacgacct
     1261 acagtctgga gcacgccaac gaccttcgag tggaagtgca gaaagtgtac gagctaatag
     1321 atgctttaag taagaagatc ttaaccttgg gcttgaacca agacccttca ccacatccaa
     1381 acactcttcg gctacagaga atgatcagat actcagctac actatttgtg caggaaaagt
     1441 tattgggttt gatgtcactg ccaaccaaag aacagtttga agaactaaaa aagaaaagga
     1501 agcaggacct ggagcagaag aggaccatgg agcgacaggc tgctctggag tcccgacgga
     1561 agcttgagga aaggcagagt ggtttggcat ctcatacagc caatggggac atgaggtctc
     1621 ttcaaggcat acctgccccc ttgcgaaagg ctgagggctg gctcccactg tcagaaggtc
     1681 aggtacagag tgaagacccc gaccctctcc ttcagcagat ctataacatt acatcgttca
     1741 tcaggcaggc caaggctgca ggccgcacag atgaggtgcg cacacttcaa gagaacctgc
     1801 ggcagctgca agatgagtat gaccagcagc agactgagaa ggccatcgaa ctgtcccgga
     1861 ggcaggctga ggaggaggag ctacagcggg agcagttaca gatgctccgc cagcgggagc
     1921 tggaacgaga agaagagcag ttcctggcag catctctgca aacacggact cgtgttctag
     1981 aactccgaga agttttaccc ttccagttgg agcccatccg agggcctcac actgatcttg
     2041 cctattcctt agatgaggac tcctccccag ttcagagcag cacagctcct gatatccttt
     2101 cacctggctc agctctagca cccatccatg tgtggtctgg gtccccagcc cttagccaag
     2161 aattactcct tcagagcacc atatcacagc caagtagtaa gacctctctc aacccgtttg
     2221 atgaagaaga cctctccagc cctatagagg gtgctgtcag ccctgctgct gtagaggctt
     2281 tcctgggccc tccagctgct gtcaccaaag aatacaatcc ttttgaggaa gatgctgagg
     2341 aagaggaggt ggcagagttg ggggcaggga atcccttcac tgacccagac agtccagcac
     2401 ccaacccctt tgatgaggat gaccatccca ggtctgccag tccagccgcc cctggaaacc
     2461 cttttgaaga gtgtccatgc accaacccct ttgaggtaga cagtgatagt ggcatggagg
     2521 ctgaggaaca cattgaggag gagctgctcc tgcagcaaat tgacaacatc aaggcttaca
     2581 tcttcgatgc caagcagtgt ggtcgaatgg atgaggttga ggttctgacg gagaacctcc
     2641 gggagctgaa gtgcaccctg gctaagcaga agggggcccc taactgacag cagtgggcag
     2701 gaactgggca gagtctttgg tagcatgata tcaagtggga ggaggagatg ggcaggcgcc
     2761 tgaaacgcac acaggtgggg gttggaaata gtagtctctt gctgtgcact ttgagacatt
     2821 tccactatag ttgaacaaga acaggaaaaa aatcggcatt atttgctggt ttttctgtat
     2881 ttcttttaat gaagtgttcc cttttcaggg gactttatga ttttatttat tgagatacag
     2941 agctgggcca aggtagaaat ggctcctggg tacctctttg tccattttct gctgactgtt
     3001 cttggtcatt atgcagtatt atagggaagc ccttaacaga ccccttccac tagccaagat
     3061 aggcaggggc tcagcaggag tctgtcctga cttggttgct tcctttcagc acctccctgc
     3121 ttggactatc tcttggacac ttagggagat gctgtgtgaa ggcagagtct aaacccagtg
     3181 ggcaccagtg cctcttttta cagatggcag gaatgttgcc agtgttgccc cctcccagtt
     3241 aaaggaagta aagttcccaa gtgtgagggt ggtggggtgg tggtgtcagt gtgagcttga
     3301 ctatgagaca gtagtgatca acttcttggt ggatgttatg gtttgggaga actttctact
     3361 tgtgcagttg tcagcccctg gggtttgata gaacgaccac tatataggtc acattcaagg
     3421 gcctgtgact tgggaattgt gactggttag tttctgtgga atattagtag gtgatggaac
     3481 acttctgagt caggagataa attctagtaa cttccaaggc cctcacgtca gccttcttcc
     3541 atgtggttca ttctggaaac tggtaagatg ttattttact acttcgagta ctgaaagaca
     3601 gaaatatttg aggcatagcc tgagatcatt ccacagctct gaagtacttg aactcttgat
     3661 agaagacaga aagggaagtt atgtagctta gtactttggt ttacaggaac aggtcagttg
     3721 acagatgacc ttgtaagatc cttggtgtgc tcagctctgg gtcatttctt tagttaatgg
     3781 acaataactg tctactagtc actttccctt tagctagctc tgggccgtgc cttttgttcg
     3841 ctactggtgt gcaagctcaa attcttctct cacattctgg tgaagatctg tcttggtggt
     3901 aagaatacca tgtgggtgca aagatctcta ttttggcagc tttaatccca attcatagta
     3961 cctgttgggg ctttggctgg atagaaagcc cacttggaga ggaagggtaa gaaccctttg
     4021 gggttctgga aggtaagcag cctggcatcg tatgttacct ggggcaggct tcccctcttt
     4081 ctaaagccta gtccccaggc atgcccagca catcaccctg cttcatctgc ttctgtgtga
     4141 tggaaaagga ggcagctcta aaataaggat gaagctgaat actggttttc accattactt
     4201 ttcctgacac agatcaggtg ttcagggtgg ttcaactgca gacattgctt ttcttataag
     4261 aatggctttc ttaattagct agtgactcat taaatgtact cctttctgga actcactcta
     4321 gatagcagtc taacagagca tggggaaaac agatgctttt caacagccat ttcttaaatc
     4381 ccgattgaat tttaaaccaa gtgaactcag attccagagg ttttactgag tttcttattg
     4441 aattcctctt tgatcatatt ctgaaagtca gagacataac aagagagaca tgtctaccca
     4501 ttggctgtat cacttcccag aattcctaca agtcagttgg tttgcagagg gtgtttggcc
     4561 tgtgagtgaa ccacagtgcc agcttcttac cttgggtgaa tatttcatga ttcccaaggt
     4621 cccaagctcc acctcagcag tgaaggagca catccttgat aaggtattgg cagatccctt
     4681 aggtgtaggt cctgttcaca gtggaagggc ttcttgcttt gttcccttct aacacactaa
     4741 ggaactggag cctcactcat tgcacttacc acacatcatg tctttgttgt cagatgttaa
     4801 aacatctttc taagtcatca tgagccatgt tgcatagcag tgccatgcag ttcaaattgt
     4861 ggaattggcc tctggacaag gtcagactag aggagcatgg tgttctggta atcatgatga
     4921 ctgtcagcaa gatggtcatt gacgcacatg cactacactg gggccttgta tcagaggctt
     4981 ttattaaaaa aatatcattt atgtgaggct tttattaaaa aaaataacat gttcatggct
     5041 gg
//
