LOCUS       NP_001101345             783 aa            linear   ROD 26-FEB-2024
DEFINITION  rabenosyn-5 [Rattus norvegicus].
ACCESSION   NP_001101345 XP_001076679 XP_232195
VERSION     NP_001101345.1
DBSOURCE    REFSEQ: accession NM_001107875.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 783)
  AUTHORS   Mishra A, Eathiraj S, Corvera S and Lambright DG.
  TITLE     Structural basis for Rab GTPase recognition and endosome tethering
            by the C2H2 zinc finger of Early Endosomal Autoantigen 1 (EEA1)
  JOURNAL   Proc Natl Acad Sci U S A 107 (24), 10866-10871 (2010)
   PUBMED   20534488
REFERENCE   2  (residues 1 to 783)
  AUTHORS   Naslavsky N, McKenzie J, Altan-Bonnet N, Sheff D and Caplan S.
  TITLE     EHD3 regulates early-endosome-to-Golgi transport and preserves
            Golgi morphology
  JOURNAL   J Cell Sci 122 (Pt 3), 389-400 (2009)
   PUBMED   19139087
REFERENCE   3  (residues 1 to 783)
  AUTHORS   Kang D, Oh S, Ahn SM, Lee BH and Moon MH.
  TITLE     Proteomic analysis of exosomes from human neural stem cells by flow
            field-flow fractionation and nanoflow liquid chromatography-tandem
            mass spectrometry
  JOURNAL   J Proteome Res 7 (8), 3475-3480 (2008)
   PUBMED   18570454
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473957.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_232195.2, XP_001076679.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     Protein         1..783
                     /product="rabenosyn-5"
                     /note="zinc finger, FYVE domain containing 20"
                     /calculated_mol_wt=88347
     Region          150..261
                     /region_name="FYVE_RBNS5"
                     /note="FYVE domain found in FYVE finger-containing Rab5
                     effector protein rabenosyn-5 (Rbsn-5) and similar
                     proteins; cd15716"
                     /db_xref="CDD:277256"
     Site            order(153,156,174..179,181..182,249..251)
                     /site_type="other"
                     /note="putative phosphatidylinositol 3-phosphate binding
                     site [chemical binding]"
                     /db_xref="CDD:277256"
     Region          460..498
                     /region_name="Rbsn"
                     /note="Rabenosyn Rab binding domain; pfam11464"
                     /db_xref="CDD:463283"
     Region          548..726
                     /region_name="NPF"
                     /note="Rabosyn-5 repeating NPF sequence-motif; pfam16601"
                     /db_xref="CDD:406900"
     Region          740..778
                     /region_name="Rbsn"
                     /note="Rabenosyn Rab binding domain; pfam11464"
                     /db_xref="CDD:463283"
     CDS             1..783
                     /gene="Rbsn"
                     /gene_synonym="Zfyve20"
                     /coded_by="NM_001107875.1:336..2687"
                     /db_xref="GeneID:312562"
                     /db_xref="RGD:1305397"
ORIGIN      
        1 maslddagev regflcplcl kdlqsfyqlq shyeeehsgd rdvkgqiknl vqkarkaknk
       61 llkregddrv epgtqgyesf syggvdpymw epqelgamrs hlsdfkkhra aridhyviev
      121 nkliirlekl tafdrtntet skiraieksv vpwvndqdvp fcpdcgnkfs irnrrhhcrl
      181 cgsimckkcm eliglplank ltsaskdsls thtspsqspn svhgsrrgsi ssmssvssvl
      241 dekdderirc cthckdtllk reqqmdekeh tpdivklyek lrlcmekvdq kapeyirmaa
      301 slnagettys lehandlrve vqkvyelida lskkiltlgl nqdpsphpnt lrlqrmirys
      361 atlfvqekll glmslptkeq feelkkkrkq dleqkrtmer qaalesrrkl eerqsglash
      421 tangdmrslq gipaplrkae gwlplsegqv qsedpdpllq qiynitsfir qakaagrtde
      481 vrtlqenlrq lqdeydqqqt ekaielsrrq aeeeelqreq lqmlrqrele reeeqflaas
      541 lqtrtrvlel revlpfqlep irgphtdlay sldedsspvq sstapdilsp gsalapihvw
      601 sgspalsqel llqstisqps sktslnpfde edlsspiega vspaaveafl gppaavtkey
      661 npfeedaeee evaelgagnp ftdpdspapn pfdeddhprs aspaapgnpf eecpctnpfe
      721 vdsdsgmeae ehieeelllq qidnikayif dakqcgrmde vevltenlre lkctlakqkg
      781 apn
//
