LOCUS       NM_013162                904 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus retinol binding protein 4 (Rbp4), mRNA.
ACCESSION   NM_013162 XM_001080229 XM_215285
VERSION     NM_013162.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 904)
  AUTHORS   Zhang,Y., Zhang,Y., Tan,Y., Luo,X. and Jia,R.
  TITLE     Increased RBP4 and Asprosin Are Novel Contributors in Inflammation
            Process of Periodontitis in Obese Rats
  JOURNAL   Int J Mol Sci 24 (23), 16739 (2023)
   PUBMED   38069063
  REMARK    GeneRIF: Increased RBP4 and Asprosin Are Novel Contributors in
            Inflammation Process of Periodontitis in Obese Rats.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 904)
  AUTHORS   Sheng,B.W., Zhang,J.Q., Chen,M. and Ma,M.
  TITLE     The inverse association between fasting blood glucose and the
            occurrence of gallbladder cancer in type 2 diabetes mellitus
            patients: a case-control study
  JOURNAL   J Cancer Res Clin Oncol 149 (12), 10387-10398 (2023)
   PUBMED   37273108
REFERENCE   3  (bases 1 to 904)
  AUTHORS   Zhou,W., Yuan,X., Li,J., Wang,W. and Ye,S.
  TITLE     Retinol binding protein 4 promotes the phenotypic transformation of
            vascular smooth muscle cells under high glucose condition via
            modulating RhoA/ROCK1 pathway
  JOURNAL   Transl Res 259, 13-27 (2023)
   PUBMED   37003483
  REMARK    GeneRIF: Retinol binding protein 4 promotes the phenotypic
            transformation of vascular smooth muscle cells under high glucose
            condition via modulating RhoA/ROCK1 pathway.
REFERENCE   4  (bases 1 to 904)
  AUTHORS   Valencia-Martinez,A., Schaefer-Graf,U., Amusquivar,E., Herrera,E.
            and Ortega-Senovilla,H.
  TITLE     Relationship of ANGPTL6 With Neonatal Glucose Homeostasis and Fat
            Mass Is Disrupted in Gestational Diabetic Pregnancies
  JOURNAL   J Clin Endocrinol Metab 107 (10), e4078-e4085 (2022)
   PUBMED   35876300
REFERENCE   5  (bases 1 to 904)
  AUTHORS   Liu,C., Zhou,X.R., Ye,M.Y., Xu,X.Q., Zhang,Y.W., Liu,H. and
            Huang,X.Z.
  TITLE     RBP4 Is Associated With Insulin Resistance in Hyperuricemia-Induced
            Rats and Patients With Hyperuricemia
  JOURNAL   Front Endocrinol (Lausanne) 12, 653819 (2021)
   PUBMED   34177800
  REMARK    GeneRIF: RBP4 Is Associated With Insulin Resistance in
            Hyperuricemia-Induced Rats and Patients With Hyperuricemia.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 904)
  AUTHORS   Wu,Q.X.
  TITLE     [Amplification and desensitization in platelet activation]
  JOURNAL   Sheng Li Ke Xue Jin Zhan 23 (3), 199-203 (1992)
   PUBMED   1299958
  REMARK    Review article
REFERENCE   7  (bases 1 to 904)
  AUTHORS   Laurent,B.C., Nilsson,M.H., Bavik,C.O., Jones,T.A., Sundelin,J. and
            Peterson,P.A.
  TITLE     Characterization of the rat retinol-binding protein gene and its
            comparison to the three-dimensional structure of the protein
  JOURNAL   J Biol Chem 260 (21), 11476-11480 (1985)
   PUBMED   4044565
REFERENCE   8  (bases 1 to 904)
  AUTHORS   Sundelin,J., Laurent,B.C., Anundi,H., Tragardh,L., Larhammar,D.,
            Bjorck,L., Eriksson,U., Akerstrom,B., Jones,A., Newcomer,M. et al.
  TITLE     Amino acid sequence homologies between rabbit, rat, and human serum
            retinol-binding proteins
  JOURNAL   J Biol Chem 260 (10), 6472-6480 (1985)
   PUBMED   3838985
REFERENCE   9  (bases 1 to 904)
  AUTHORS   Fex,G. and Hansson,B.
  TITLE     Retinol-binding protein from human urine and its interaction with
            retinol and prealbumin
  JOURNAL   Eur J Biochem 94 (1), 307-313 (1979)
   PUBMED   571335
REFERENCE   10 (bases 1 to 904)
  AUTHORS   Peterson,P.A., Rask,L., Ostberg,L., Andersson,L., Kamwendo,F. and
            Pertoft,H.
  TITLE     Studies on the transport and cellular distribution of vitamin A in
            normal and vitamin A-deficient rats with special reference to the
            vitamin A-binding plasma protein
  JOURNAL   J Biol Chem 248 (11), 4009-4022 (1973)
   PUBMED   4708098
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CO561550.1 and DV725071.1.
            
            On or before Oct 13, 2007 this sequence version replaced
            XM_001080229.1, XM_215285.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CF108847.1, BC167099.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-541               CO561550.1         1-541
            542-904             DV725071.1         341-703
FEATURES             Location/Qualifiers
     source          1..904
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..904
                     /gene="Rbp4"
                     /gene_synonym="RBPA"
                     /note="retinol binding protein 4"
                     /db_xref="GeneID:25703"
                     /db_xref="RGD:3546"
     exon            1..32
                     /gene="Rbp4"
                     /gene_synonym="RBPA"
                     /inference="alignment:Splign:2.1.0"
     exon            33..161
                     /gene="Rbp4"
                     /gene_synonym="RBPA"
                     /inference="alignment:Splign:2.1.0"
     CDS             51..656
                     /gene="Rbp4"
                     /gene_synonym="RBPA"
                     /note="retinol binding protein 4, plasma; RBP; PRBP;
                     plasma retinol-binding protein"
                     /codon_start=1
                     /product="retinol-binding protein 4 precursor"
                     /protein_id="NP_037294.1"
                     /db_xref="GeneID:25703"
                     /db_xref="RGD:3546"
                     /translation="MEWVWALVLLAALGGGSAERDCRVSSFRVKENFDKARFSGLWYA
                     IAKKDPEGLFLQDNIIAEFSVDEKGHMSATAKGRVRLLSNWEVCADMVGTFTDTEDPA
                     KFKMKYWGVASFLQRGNDDHWIIDTDYDTFALQYSCRLQNLDGTCADSYSFVFSRDPN
                     GLTPETRRLVRQRQEELCLERQYRWIEHNGYCQSRPSRNSL"
     exon            162..298
                     /gene="Rbp4"
                     /gene_synonym="RBPA"
                     /inference="alignment:Splign:2.1.0"
     exon            299..405
                     /gene="Rbp4"
                     /gene_synonym="RBPA"
                     /inference="alignment:Splign:2.1.0"
     exon            406..618
                     /gene="Rbp4"
                     /gene_synonym="RBPA"
                     /inference="alignment:Splign:2.1.0"
     exon            619..904
                     /gene="Rbp4"
                     /gene_synonym="RBPA"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcggcca ggcttgcacg cggcttctgc tgggcagact ccggtgtgaa atggagtggg
       61 tgtgggcgct cgtgctgctg gcggctctgg gaggcggcag cgccgagcgc gactgcaggg
      121 tgagcagctt cagagtcaag gagaacttcg acaaggctcg tttctctggg ctctggtatg
      181 ccatcgccaa aaaggatccc gagggtctct ttttgcaaga caacatcatc gctgagtttt
      241 ctgtggacga gaagggtcat atgagcgcta cagccaaggg acgagtccgt cttctgagca
      301 actgggaagt gtgtgcagac atggtgggca ctttcacaga cacagaagat cctgccaagt
      361 tcaagatgaa gtactggggt gtagcctcct ttctccagcg aggaaacgat gaccactgga
      421 tcatcgatac ggactacgac accttcgctc tgcagtattc ctgccgcctg cagaatctgg
      481 atggcacctg tgcagacagc tactcctttg tgttttctcg tgaccccaat ggcctgaccc
      541 cggagacacg gaggctggtg aggcagcgac aggaggagct gtgcctagag aggcagtaca
      601 gatggatcga gcacaatggt tactgtcaaa gcagaccctc aagaaacagt ttgtagcaac
      661 gtcaaggatg tataaagttg gaaaacttct gattagctct catccagtct tcatctctat
      721 ttatcttaga agtttagttt ccccacctcc cctcccttct ctaggtggac attaaaacca
      781 tcgtccaaat acatgggaat gcctgaatcc attcacacaa acgtgtatct tactgagaag
      841 ttccccgaga gacgtttgag gcttgggatt ccaaacttga tttattaaac gtatagtcac
      901 catc
//
