LOCUS       NM_001191832            3777 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus retinol binding protein 3 (Rbp3), mRNA.
ACCESSION   NM_001191832 XM_341400
VERSION     NM_001191832.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3777)
  AUTHORS   Chiasserini,D., van Weering,J.R., Piersma,S.R., Pham,T.V.,
            Malekzadeh,A., Teunissen,C.E., de Wit,H. and Jimenez,C.R.
  TITLE     Proteomic analysis of cerebrospinal fluid extracellular vesicles: a
            comprehensive dataset
  JOURNAL   J Proteomics 106, 191-204 (2014)
   PUBMED   24769233
REFERENCE   2  (bases 1 to 3777)
  AUTHORS   Daiger,S.P., Sullivan,L.S. and Bowne,S.J.
  TITLE     Genes and mutations causing retinitis pigmentosa
  JOURNAL   Clin Genet 84 (2), 132-141 (2013)
   PUBMED   23701314
  REMARK    Review article
REFERENCE   3  (bases 1 to 3777)
  AUTHORS   Li,S., Yang,Z., Hu,J., Gordon,W.C., Bazan,N.G., Haas,A.L., Bok,D.
            and Jin,M.
  TITLE     Secretory defect and cytotoxicity: the potential disease mechanisms
            for the retinitis pigmentosa (RP)-associated interphotoreceptor
            retinoid-binding protein (IRBP)
  JOURNAL   J Biol Chem 288 (16), 11395-11406 (2013)
   PUBMED   23486466
REFERENCE   4  (bases 1 to 3777)
  AUTHORS   Garlipp,M.A., Nowak,K.R. and Gonzalez-Fernandez,F.
  TITLE     Cone outer segment extracellular matrix as binding domain for
            interphotoreceptor retinoid-binding protein
  JOURNAL   J Comp Neurol 520 (4), 756-769 (2012)
   PUBMED   21935947
REFERENCE   5  (bases 1 to 3777)
  AUTHORS   Kiser,P.D., Golczak,M., Maeda,A. and Palczewski,K.
  TITLE     Key enzymes of the retinoid (visual) cycle in vertebrate retina
  JOURNAL   Biochim Biophys Acta 1821 (1), 137-151 (2012)
   PUBMED   21447403
  REMARK    Review article
REFERENCE   6  (bases 1 to 3777)
  AUTHORS   Suzuki,H., Tsuchiya,K. and Takezaki,N.
  TITLE     A molecular phylogenetic framework for the Ryukyu endemic rodents
            Tokudaia osimensis and Diplothrix legata
  JOURNAL   Mol Phylogenet Evol 15 (1), 15-24 (2000)
   PUBMED   10764531
REFERENCE   7  (bases 1 to 3777)
  AUTHORS   Serizawa,K., Suzuki,H. and Tsuchiya,K.
  TITLE     A phylogenetic view on species radiation in Apodemus inferred from
            variation of nuclear and mitochondrial genes
  JOURNAL   Biochem Genet 38 (1-2), 27-40 (2000)
   PUBMED   10862357
REFERENCE   8  (bases 1 to 3777)
  AUTHORS   Katz,M.L., Gao,C.L. and Stientjes,H.J.
  TITLE     Regulation of the interphotoreceptor retinoid-binding protein
            content of the retina by vitamin A
  JOURNAL   Exp Eye Res 57 (4), 393-401 (1993)
   PUBMED   8282025
REFERENCE   9  (bases 1 to 3777)
  AUTHORS   Gonzalez-Fernandez,F., Van Niel,E., Edmonds,C., Beaver,H.,
            Nickerson,J.M., Garcia-Fernandez,J.M., Campohiaro,P.A. and
            Foster,R.G.
  TITLE     Differential expression of interphotoreceptor retinoid-binding
            protein, opsin, cellular retinaldehyde-binding protein, and basic
            fibroblastic growth factor
  JOURNAL   Exp Eye Res 56 (4), 411-427 (1993)
   PUBMED   7916695
  REMARK    Erratum:[Exp Eye Res 1993 Jul;57(1):127]
REFERENCE   10 (bases 1 to 3777)
  AUTHORS   Gonzalez-Fernandez,F. and Healy,J.I.
  TITLE     Early expression of the gene for interphotoreceptor retinol-binding
            protein during photoreceptor differentiation suggests a critical
            role for the interphotoreceptor matrix in retinal development
  JOURNAL   J Cell Biol 111 (6 Pt 1), 2775-2784 (1990)
   PUBMED   1703544
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Jul 17, 2010 this sequence version replaced XM_341400.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.1203846.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3120              JAXUCZ010000016.1  9273787-9276906
            3121-3311           JAXUCZ010000016.1  9278215-9278405
            3312-3454           JAXUCZ010000016.1  9280378-9280520
            3455-3777           JAXUCZ010000016.1  9281933-9282255
FEATURES             Location/Qualifiers
     source          1..3777
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p16"
     gene            1..3777
                     /gene="Rbp3"
                     /gene_synonym="Irbp"
                     /note="retinol binding protein 3"
                     /db_xref="GeneID:24711"
                     /db_xref="RGD:3545"
     exon            1..3120
                     /gene="Rbp3"
                     /gene_synonym="Irbp"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..3777
                     /gene="Rbp3"
                     /gene_synonym="Irbp"
                     /note="retinol-binding protein 2; interphotoreceptor
                     retinol- binding protein; interphotoreceptor retinoid
                     binding protein; retinol binding protein 3, interstitial"
                     /codon_start=1
                     /product="retinol-binding protein 3 precursor"
                     /protein_id="NP_001178761.1"
                     /db_xref="GeneID:24711"
                     /db_xref="RGD:3545"
                     /translation="MMREWVLVLSTLLCVLAGPTHLFQPSLVLDMAKVLLDNYCFPEN
                     LMGMQAAIEQAMKSHEILGISDPQTLAHVLTVGVQSSLNDPRLFISYEPSTLEAPQQA
                     PALTDLTREELLAQIQRNIRHEVLEDNVGYLRVDDLPGQEVLSELGEFLVSHVWKQLT
                     GTSSLVLDLRHCAGGHVSGIPYVISYLHPGNTVLHVDTIYDRPSNTTTEIWTLPKVLG
                     ERYSADKDVVVLTSGHTGGVAEDIAYILKQMRRAIVVGERTEGGALDLQKLRIGQSDF
                     FLTVPVSRSLGPLGGGGQTWEGSGVLPCVGIPAEQALEKALAILTLRRALPGVVLRLQ
                     EALQDYYTLVDRVPGLLHHLASMDYSAVVSEEDLVTKLNAGLQAVSEDPRLLVRATGP
                     RETPSRPETGPNEPPAVTPEVPKEEDARRALVDSVFQVSVLPGNVGYLRFDRFADASV
                     LKTLGPYVLRQVWEPLQDTEHLIMDLRHNPGGPSSAVPLVLSYFQGPEAGPVRLFTTY
                     DRRTNITQEHFSHKELLGQRYGNRRGVYLLTSHRTATAAEEFAFLMQSLSWATLVGEI
                     TAGSLLHTCTVPLLDSPEGGLTLTVPVLTFIDNHGEAWLGGGVVPDAIVLAEEALERA
                     QEVLDFHRSLGALVEGTGRLLEAHYARPEIAEQARDLLQSKLAQGAYRTAVDLESLAS
                     QLTADLQEVSEDHRLLVFHSPGELVAEEVPLPPPAIPSPEELSYLIEALFKTDVLPGH
                     LGYLRFDAMAELETVKAIGPQLVRLVWQRLVDTAALVVDLRYNPGSYSSAVPLLCSYF
                     FEEEPRQHLYSVFDRATSRVTEIWTLPLVAGQRYGSHKDLYILMSHTSGSAAEAFAHT
                     MQDLQRATVIGEPTAGGALSVGIYQVDNSPLYASMPTQMALSATTGEAWDLAGVEPDI
                     TVPMSEALSTAQDIVALRAKVPTVLQTAGKLVADNYASPELGAKMAAKLSGLQSRYAR
                     VTSEGALAEMLGADLQMLSGDPHLKTAHIPEDAKDRIPGIVPMQIPSPEVFEDLIKFS
                     FHTNVFEDNIGYLRFDMFGDCELLIQVSELLVEHIWKKIVHTDALIIDMRFNIGGPTS
                     SISALCSYFFDEAPPVLLDKIYNRPNDSISELWTHSQLTGERYGSKKSVAILTSGVTA
                     GAAEEFTYIMKRLGRALVVGEVTSGGCQPPQTYHVDDTHLYITIPTARSVGATDGSSW
                     EGVGVTPNVVVSSELALTRAKEILQRALRA"
     exon            3121..3311
                     /gene="Rbp3"
                     /gene_synonym="Irbp"
                     /inference="alignment:Splign:2.1.0"
     exon            3312..3454
                     /gene="Rbp3"
                     /gene_synonym="Irbp"
                     /inference="alignment:Splign:2.1.0"
     exon            3455..3777
                     /gene="Rbp3"
                     /gene_synonym="Irbp"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggagcagg gccacagtct tgtacacagt caagggagct ctgacccagc agctggggct
       61 ccagggatcc caatgatgag agaatgggtc ctggttttgt ccacactgct atgtgttctg
      121 gctggtccca cgcacctctt ccagccaagc ctggtactgg atatggccaa ggtcctcctg
      181 gataactact gcttccccga gaacctgatg ggaatgcaag cggcgattga gcaggctatg
      241 aagagtcatg agattctggg catctcggac cctcagacgc tggcccatgt gctgacagtt
      301 ggagtccaga gctctttgaa tgacccacgt ctcttcatct cctatgagcc cagtaccctc
      361 gaggcccccc agcaagcacc agcactcacc gacctcaccc gagaagagct gctggcccag
      421 atacagagga acatccgcca tgaggttctt gaggataacg tgggctacct acgagtggat
      481 gatctccctg gacaggaggt actgagtgag ctgggggagt tcctagtgag ccatgtgtgg
      541 aagcagctca cgggcacctc ctccttggtg ctagatctcc gtcactgtgc tggtggtcat
      601 gtctctggga tcccttatgt catctcctac ttgcaccctg ggaacacagt cttgcacgtg
      661 gataccatct acgatcggcc ctccaacacc accacagaga tctggacctt gcctaaggtc
      721 ctgggggaga gatacagtgc agacaaggat gtggtggtcc tcaccagtgg acacactggg
      781 ggagtagccg aggacatcgc ttacatcctc aagcagatgc gcagggccat cgtggtgggt
      841 gagcggacgg aaggtggcgc cctggacctc cagaagctga gaataggtca gtctgacttc
      901 ttccttacag tgcctgtgtc caggtccctg gggcccctag gtggaggcgg ccaaacatgg
      961 gaaggcagcg gggtgctgcc ctgtgtgggg atacctgcag agcaagccct agaaaaggcc
     1021 ctggccatcc tcaccctgcg acgtgccctg ccaggcgttg tcctccgact ccaggaagcc
     1081 ctacaggact attacacatt agtggaccga gtgccgggcc tgctgcacca cctggccagc
     1141 atggactact cggccgtggt ctccgaagag gacctggtga caaagctcaa tgctggtttg
     1201 caggctgtgt cggaggatcc caggctcctg gtgagagcca ccggacccag agaaaccccc
     1261 tcaagacctg agactggccc taacgagcca ccagcagtca cccctgaggt gcctaaggaa
     1321 gaagatgccc ggagggccct agtggattcc gtgtttcagg tgtccgtgct gccgggcaat
     1381 gtgggctacc tgcgctttga cagatttgca gatgcctctg tgctgaagac actgggccct
     1441 tatgtgctgc ggcaggtgtg ggagcccctg caggacacag agcacctcat catggacctg
     1501 cgtcacaacc ctgggggtcc gtcctctgcc gtgcctctgg ttctgtccta ctttcagggt
     1561 ccggaggctg ggcccgtacg gctcttcacc acctatgacc gtcgcaccaa catcacccag
     1621 gagcatttca gccacaagga gctgctaggc caacgatacg gcaaccggcg tggggtgtac
     1681 ctgcttacta gccacaggac tgccacggct gcggaagagt ttgccttcct catgcagtcg
     1741 ctgagctggg ccacgctggt aggggaaatc accgcgggca gcctgctcca cacctgcacg
     1801 gtgccactgc tggactcgcc ggagggtggc ctgacgctca cggtacccgt gctaactttt
     1861 atcgacaacc acggtgaggc ctggctaggg ggtggggtgg tgcctgacgc catcgtgctg
     1921 gctgaggaag ccttagagag agctcaggag gtgctggatt tccatcgcag tctgggtgcc
     1981 ttggtagagg gcaccggtcg cctgctggag gctcactatg cccggccgga gatcgcagag
     2041 caggccagag atctcctgca gtctaagctg gcccaaggag cctaccgcac ggctgtggac
     2101 ttggagtcgc tggcctcaca gctcactgct gaccttcagg aggtgtctga ggaccaccgt
     2161 ctgttggtgt tccacagccc cggtgagctg gtggcggagg aggtccccct gccgccccct
     2221 gccatcccgt ccccagagga actctcctat ctcatagagg ccctgttcaa aacagacgtg
     2281 ctgccaggcc atctgggcta cttgcgtttt gacgccatgg ctgagctgga gacagtaaag
     2341 gccattgggc ctcagctagt gcggctggtg tggcagaggc tggtggacac ggctgcactg
     2401 gtggttgacc tgcgctacaa tcccggcagc tactcctctg ccgttccgct gctctgctcc
     2461 tacttttttg aggaagagcc ccgccagcac ctctactccg tttttgacag ggcgacatcg
     2521 agggtcacag agatatggac cctgccgctg gttgccggtc aacgctacgg ctcccataag
     2581 gatctctaca tcctcatgag ccataccagc ggctctgcag ctgaggcctt tgctcacact
     2641 atgcaggatc tacagcgggc caccgtcata ggagagccca cagctggagg ggcactctcc
     2701 gtgggcatct accaggtgga caatagcccc ttatatgcct ccatgcccac tcagatggcc
     2761 ctgagtgcca ccactggtga ggcctgggac ttggctggtg tggaacccga catcactgtg
     2821 cccatgagcg aggccctttc cacagcccag gacatagtgg ccctgcgtgc caaggtgccc
     2881 acagtcctgc agacagccgg gaaactagtg gccgataact atgcgtcccc tgaactggga
     2941 gccaagatgg ctgccaagct cagcggtctg cagagccgat atgcaagggt gacttcagaa
     3001 ggggccttgg cagagatgct gggggcggac ctgcaaatgc tctctgggga cccacacctg
     3061 aagacggcac acatcccaga agatgccaaa gacagaattc ctggaattgt gcccatgcag
     3121 attccctccc cagaagtctt tgaggacctg atcaaatttt ccttccacac aaatgtattt
     3181 gaggacaaca ttggctacct gaggttcgac atgtttgggg attgtgagct acttatccag
     3241 gtctcagagc tgctggtaga acacatctgg aagaagatcg tgcacactga tgccctcatc
     3301 atcgacatga gatttaacat cggcggcccc acctcctcca tctcagccct gtgctcctac
     3361 ttctttgacg aggcacctcc cgttctgctg gacaagatct acaaccggcc caacgactcg
     3421 atcagcgaac tttggacaca ctcgcagctc acaggtgaac gatatggctc caagaagagt
     3481 gtagccatcc tgaccagcgg tgtgacagcc ggcgccgccg aggaatttac ttacatcatg
     3541 aagaggctgg gccgggccct ggtcgttggt gaagtgacaa gtggaggctg ccagccacca
     3601 cagacctacc acgtggacga cacgcatctc tatatcacca tccccacagc tcgctctgtg
     3661 ggcgccacgg acggcagttc ctgggaaggg gtgggtgtga cacctaatgt agttgtctct
     3721 tcagaattgg ctcttaccag agccaaggag atactccagc gggccctgag ggcgtaa
//
