LOCUS       NM_012733                696 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus retinol binding protein 1 (Rbp1), mRNA.
ACCESSION   NM_012733
VERSION     NM_012733.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Otake,H., Yamamoto,T., Deguchi,S., Taga,A. and Nagai,N.
  TITLE     Retinal proteomic evaluation of rats following
            streptozotocin-injection using shotgun proteomics
  JOURNAL   Mol Med Rep 21 (1), 379-386 (2020)
   PUBMED   31746385
  REMARK    GeneRIF: Retinal proteomic evaluation of rats following
            streptozotocininjection using shotgun proteomics.
REFERENCE   2  (bases 1 to 696)
  AUTHORS   Spade,D.J., Hall,S.J., Wortzel,J.D., Reyes,G. and Boekelheide,K.
  TITLE     All-trans Retinoic Acid Disrupts Development in Ex Vivo Cultured
            Fetal Rat Testes. II: Modulation of Mono-(2-ethylhexyl) Phthalate
            Toxicity
  JOURNAL   Toxicol Sci 168 (1), 149-159 (2019)
   PUBMED   30476341
REFERENCE   3  (bases 1 to 696)
  AUTHORS   Spade,D.J., Dere,E., Hall,S.J., Schorl,C., Freiman,R.N. and
            Boekelheide,K.
  TITLE     All-Trans Retinoic Acid Disrupts Development in Ex Vivo Cultured
            Fetal Rat Testes. I: Altered Seminiferous Cord Maturation and
            Testicular Cell Fate
  JOURNAL   Toxicol Sci 167 (2), 546-558 (2019)
   PUBMED   30329139
REFERENCE   4  (bases 1 to 696)
  AUTHORS   Menozzi,I., Vallese,F., Polverini,E., Folli,C., Berni,R. and
            Zanotti,G.
  TITLE     Structural and molecular determinants affecting the interaction of
            retinol with human CRBP1
  JOURNAL   J Struct Biol 197 (3), 330-339 (2017)
   PUBMED   28057518
REFERENCE   5  (bases 1 to 696)
  AUTHORS   Kaiser,M.F., Johnson,D.C., Wu,P., Walker,B.A., Brioli,A.,
            Mirabella,F., Wardell,C.P., Melchor,L., Davies,F.E. and Morgan,G.J.
  TITLE     Global methylation analysis identifies prognostically important
            epigenetically inactivated tumor suppressor genes in multiple
            myeloma
  JOURNAL   Blood 122 (2), 219-226 (2013)
   PUBMED   23699600
REFERENCE   6  (bases 1 to 696)
  AUTHORS   Noy,N. and Blaner,W.S.
  TITLE     Interactions of retinol with binding proteins: studies with rat
            cellular retinol-binding protein and with rat retinol-binding
            protein
  JOURNAL   Biochemistry 30 (26), 6380-6386 (1991)
   PUBMED   2054343
REFERENCE   7  (bases 1 to 696)
  AUTHORS   Levin,M.S., Li,E., Ong,D.E. and Gordon,J.I.
  TITLE     Comparison of the tissue-specific expression and developmental
            regulation of two closely linked rodent genes encoding cytosolic
            retinol-binding proteins
  JOURNAL   J Biol Chem 262 (15), 7118-7124 (1987)
   PUBMED   3584109
REFERENCE   8  (bases 1 to 696)
  AUTHORS   Sherman,D.R., Lloyd,R.S. and Chytil,F.
  TITLE     Rat cellular retinol-binding protein: cDNA sequence and rapid
            retinol-dependent accumulation of mRNA
  JOURNAL   Proc Natl Acad Sci U S A 84 (10), 3209-3213 (1987)
   PUBMED   3472205
REFERENCE   9  (bases 1 to 696)
  AUTHORS   Sundelin,J., Anundi,H., Tragardh,L., Eriksson,U., Lind,P.,
            Ronne,H., Peterson,P.A. and Rask,L.
  TITLE     The primary structure of rat liver cellular retinol-binding protein
  JOURNAL   J Biol Chem 260 (10), 6488-6493 (1985)
   PUBMED   4039728
REFERENCE   10 (bases 1 to 696)
  AUTHORS   Eriksson,U., Das,K., Busch,C., Nordlinder,H., Rask,L., Sundelin,J.,
            Sallstrom,J. and Peterson,P.A.
  TITLE     Cellular retinol-binding protein. Quantitation and distribution
  JOURNAL   J Biol Chem 259 (21), 13464-13470 (1984)
   PUBMED   6541654
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 27, 2020 this sequence version replaced NM_012733.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M16459.1, FQ218090.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-168               JAXUCZ010000008.1  107904589-107904756
            169-347             JAXUCZ010000008.1  107905140-107905318
            348-449             JAXUCZ010000008.1  107924224-107924325
            450-696             JAXUCZ010000008.1  107925863-107926109
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..696
                     /gene="Rbp1"
                     /note="retinol binding protein 1"
                     /db_xref="GeneID:25056"
                     /db_xref="RGD:3543"
     exon            1..168
                     /gene="Rbp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             96..503
                     /gene="Rbp1"
                     /EC_number="2.7.7.1"
                     /note="CRBP; CRBP-I; cellular retinol-binding protein I;
                     retinol binding protein 1, cellular"
                     /codon_start=1
                     /product="retinol-binding protein 1"
                     /protein_id="NP_036865.1"
                     /db_xref="GeneID:25056"
                     /db_xref="RGD:3543"
                     /translation="MPVDFNGYWKMLSNENFEEYLRALDVNVALRKIANLLKPDKEIV
                     QDGDHMIIRTLSTFRNYIMDFQVGKEFEEDLTGIDDRKCMTTVSWDGDKLQCVQKGEK
                     EGRGWTQWIEGDELHLEMRAEGVTCKQVFKKVH"
     exon            169..347
                     /gene="Rbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            348..449
                     /gene="Rbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            450..696
                     /gene="Rbp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccttcacccg gagcgcattg gcagccacag tcccagcgga gcccacagcc gctcccgcct
       61 tctccgtgtc gggcgatccc cagtctgtcc ccaaaatgcc tgtggacttc aacgggtact
      121 ggaagatgct gagcaacgag aatttcgagg agtacctgcg tgcgctcgat gtcaacgtgg
      181 ccttgcgaaa aatcgccaac ttgctgaagc cggacaaaga gatcgtgcag gatggcgacc
      241 acatgatcat ccgcacgctg agcacttttc gaaactatat catggacttc caagttggga
      301 aggagttcga ggaggatctg acaggcatag atgaccgcaa gtgcatgacc acagtgagct
      361 gggatggtga caagcttcag tgtgttcaga agggagagaa ggagggacgt ggctggaccc
      421 agtggattga gggtgatgaa cttcacctgg agatgagagc agagggtgtg acctgcaagc
      481 aagtgttcaa gaaagtacac tgagcggccc gagcagataa ccttggtctc gaggaacaag
      541 tgggatggcc caatggtcag gagccctctc tgcctagcac agggctgaaa cacatagcca
      601 ccccaggttt ctgccagcag agtctgtctc attgccttgt ctcttttcct tttcttaaaa
      661 tgaagctacc ccaataaaaa tgatctctgt ttaaga
//
