LOCUS       NM_001271138            1486 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus RNA binding motif protein 8A (Rbm8a), mRNA.
ACCESSION   NM_001271138 XM_215637
VERSION     NM_001271138.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1486)
  AUTHORS   Zhan,X., Yan,C., Zhang,X., Lei,J. and Shi,Y.
  TITLE     Structure of a human catalytic step I spliceosome
  JOURNAL   Science 359 (6375), 537-545 (2018)
   PUBMED   29301961
REFERENCE   2  (bases 1 to 1486)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 1486)
  AUTHORS   Michelle,L., Cloutier,A., Toutant,J., Shkreta,L., Thibault,P.,
            Durand,M., Garneau,D., Gendron,D., Lapointe,E., Couture,S., Le
            Hir,H., Klinck,R., Elela,S.A., Prinos,P. and Chabot,B.
  TITLE     Proteins associated with the exon junction complex also control the
            alternative splicing of apoptotic regulators
  JOURNAL   Mol Cell Biol 32 (5), 954-967 (2012)
   PUBMED   22203037
REFERENCE   4  (bases 1 to 1486)
  AUTHORS   Gehring,N.H., Lamprinaki,S., Kulozik,A.E. and Hentze,M.W.
  TITLE     Disassembly of exon junction complexes by PYM
  JOURNAL   Cell 137 (3), 536-548 (2009)
   PUBMED   19410547
REFERENCE   5  (bases 1 to 1486)
  AUTHORS   Diem,M.D., Chan,C.C., Younis,I. and Dreyfuss,G.
  TITLE     PYM binds the cytoplasmic exon-junction complex and ribosomes to
            enhance translation of spliced mRNAs
  JOURNAL   Nat Struct Mol Biol 14 (12), 1173-1179 (2007)
   PUBMED   18026120
REFERENCE   6  (bases 1 to 1486)
  AUTHORS   Gehring,N.H., Kunz,J.B., Neu-Yilik,G., Breit,S., Viegas,M.H.,
            Hentze,M.W. and Kulozik,A.E.
  TITLE     Exon-junction complex components specify distinct routes of
            nonsense-mediated mRNA decay with differential cofactor
            requirements
  JOURNAL   Mol Cell 20 (1), 65-75 (2005)
   PUBMED   16209946
REFERENCE   7  (bases 1 to 1486)
  AUTHORS   Tange,T.O., Nott,A. and Moore,M.J.
  TITLE     The ever-increasing complexities of the exon junction complex
  JOURNAL   Curr Opin Cell Biol 16 (3), 279-284 (2004)
   PUBMED   15145352
  REMARK    Review article
REFERENCE   8  (bases 1 to 1486)
  AUTHORS   Monshausen,M., Gehring,N.H. and Kosik,K.S.
  TITLE     The mammalian RNA-binding protein Staufen2 links nuclear and
            cytoplasmic RNA processing pathways in neurons
  JOURNAL   Neuromolecular Med 6 (2-3), 127-144 (2004)
   PUBMED   15970630
REFERENCE   9  (bases 1 to 1486)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
REFERENCE   10 (bases 1 to 1486)
  AUTHORS   Kataoka,N., Yong,J., Kim,V.N., Velazquez,F., Perkinson,R.A.,
            Wang,F. and Dreyfuss,G.
  TITLE     Pre-mRNA splicing imprints mRNA in the nucleus with a novel
            RNA-binding protein that persists in the cytoplasm
  JOURNAL   Mol Cell 6 (3), 673-682 (2000)
   PUBMED   11030346
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Sep 1, 2012 this sequence version replaced XM_215637.6.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ212597.1, FQ224490.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-115               JAXUCZ010000002.1  186854036-186854150
            116-175             JAXUCZ010000002.1  186854451-186854510
            176-253             JAXUCZ010000002.1  186854627-186854704
            254-390             JAXUCZ010000002.1  186855002-186855138
            391-527             JAXUCZ010000002.1  186855587-186855723
            528-1486            JAXUCZ010000002.1  186855844-186856802
FEATURES             Location/Qualifiers
     source          1..1486
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1486
                     /gene="Rbm8a"
                     /gene_synonym="Rbm8"
                     /note="RNA binding motif protein 8A"
                     /db_xref="GeneID:295284"
                     /db_xref="RGD:1310099"
     exon            1..115
                     /gene="Rbm8a"
                     /gene_synonym="Rbm8"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..573
                     /gene="Rbm8a"
                     /gene_synonym="Rbm8"
                     /note="ribonucleoprotein RBM8A; RNA binding motif protein
                     8"
                     /codon_start=1
                     /product="RNA-binding protein 8A"
                     /protein_id="NP_001258067.1"
                     /db_xref="GeneID:295284"
                     /db_xref="RGD:1310099"
                     /translation="MADVLDLHEAGGEDFAMDEDGDESIHKLKEKAKKRKGRGFGSEE
                     GSRARMREDYDSVEQDGDEPGPQRSVEGWILFVTGVHEEATEEDIHDKFAEYGEIKNI
                     HLNLDRRTGYLKGYTLVEYETYKEAQAAMEGLNGQDLMGQPISVDWCFVRGPPKGKRR
                     GGRRRSRSPDRRRR"
     exon            116..175
                     /gene="Rbm8a"
                     /gene_synonym="Rbm8"
                     /inference="alignment:Splign:2.1.0"
     exon            176..253
                     /gene="Rbm8a"
                     /gene_synonym="Rbm8"
                     /inference="alignment:Splign:2.1.0"
     exon            254..390
                     /gene="Rbm8a"
                     /gene_synonym="Rbm8"
                     /inference="alignment:Splign:2.1.0"
     exon            391..527
                     /gene="Rbm8a"
                     /gene_synonym="Rbm8"
                     /inference="alignment:Splign:2.1.0"
     exon            528..1486
                     /gene="Rbm8a"
                     /gene_synonym="Rbm8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgaggttcc tagctactag acgcacagag agcgccgaga gaagcaagat ggcggacgtg
       61 ctggatcttc acgaggccgg gggcgaggat ttcgccatgg atgaggatgg tgacgaaagc
      121 atccacaaac taaaagaaaa agcgaagaaa cggaagggcc gcggttttgg ttctgaagag
      181 gggtcccgag cgcggatgcg ggaagattat gacagtgtgg agcaggatgg cgatgaacct
      241 ggaccacagc gctctgttga aggttggatt ctctttgtca ctggagtcca cgaagaagcc
      301 actgaagaag atatccatga caagttcgct gaatatgggg aaataaaaaa tatccacctg
      361 aatttggaca ggcgcacggg atacttgaag gggtatactc tagttgagta tgaaacatac
      421 aaagaagctc aggctgccat ggagggacta aatggtcaag atttgatggg acagccaatc
      481 agtgttgact ggtgttttgt tcgtggtcca ccaaagggca agaggagagg tggccgaaga
      541 cgaagcagga gtccagaccg aagacgccga tgagatactt aataaatcct ctgttgacca
      601 ggtggtctcc atgagtctat ttggttatgc tgccttggat aaacagggct aggatggact
      661 ttgtgtttat atttaatttc ttaccctact tggtaatttt gagtttaaga aaaaaataaa
      721 tgtcattttg ttttctacat ttaaaactgt gtttgactgt tctggaaatt ctaaacaacc
      781 tcagtgaggc cttctgagtg gttgtgaagc tacttctgtg tggcgtggcc ttctgagttt
      841 ctagaaaggc tcacagagac tgctcagcat ttctttagag catgagagtg agcaggtgta
      901 atgggttttt cttgtggtgt tcagtgaatt ttacactctt gtgagcagat gctatgtcag
      961 tgtcttgtgt agcccaggct ggctttgaac tcactgtatt gtaaagaact ttgattcttg
     1021 cctcttacct cccaagtgct aacattgcac ccatgggcca tcatacccag tttatgtggt
     1081 ctccggaatt aaaacatgga gctctgagat gctcagccag ctctactttg aatatggtgc
     1141 taaactgtga agtttgttag ttcctacaac ataaaaaccc agcttaagta ctactagacc
     1201 aatatgcaca cctttaattc cagcacttgg gaggcaggtg gatctcttga gttaggggca
     1261 acctggtcta cacaagagtt ctaagacagc cagggctaca aagacattgc tattccttta
     1321 ttatatatag tttttagctg ggatgttttt ttaggtgtgt ctgttgtaac tgatttgttg
     1381 tctgtgtggg tccctatgtg gcccacactg gcctcaaact gatgctccta tctctgtctt
     1441 cccaatgcat aatggcaaat attaaacata actttttctc agttgg
//
