LOCUS       NM_001401005            1803 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus RNA binding motif protein 7 (Rbm7), transcript
            variant 1, mRNA.
ACCESSION   NM_001401005 XM_039081439
VERSION     NM_001401005.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1803)
  AUTHORS   Bugai,A., Quaresma,A.J.C., Friedel,C.C., Lenasi,T., Duster,R.,
            Sibley,C.R., Fujinaga,K., Kukanja,P., Hennig,T., Blasius,M.,
            Geyer,M., Ule,J., Dolken,L. and Barboric,M.
  TITLE     P-TEFb Activation by RBM7 Shapes a Pro-survival Transcriptional
            Response to Genotoxic Stress
  JOURNAL   Mol Cell 74 (2), 254-267 (2019)
   PUBMED   30824372
REFERENCE   2  (bases 1 to 1803)
  AUTHORS   Hrossova,D., Sikorsky,T., Potesil,D., Bartosovic,M., Pasulka,J.,
            Zdrahal,Z., Stefl,R. and Vanacova,S.
  TITLE     RBM7 subunit of the NEXT complex binds U-rich sequences and targets
            3'-end extended forms of snRNAs
  JOURNAL   Nucleic Acids Res 43 (8), 4236-4248 (2015)
   PUBMED   25852104
REFERENCE   3  (bases 1 to 1803)
  AUTHORS   Tiedje,C., Lubas,M., Tehrani,M., Menon,M.B., Ronkina,N.,
            Rousseau,S., Cohen,P., Kotlyarov,A. and Gaestel,M.
  TITLE     p38MAPK/MK2-mediated phosphorylation of RBM7 regulates the human
            nuclear exosome targeting complex
  JOURNAL   RNA 21 (2), 262-278 (2015)
   PUBMED   25525152
REFERENCE   4  (bases 1 to 1803)
  AUTHORS   Lubas,M., Andersen,P.R., Schein,A., Dziembowski,A., Kudla,G. and
            Jensen,T.H.
  TITLE     The human nuclear exosome targeting complex is loaded onto newly
            synthesized RNA to direct early ribonucleolysis
  JOURNAL   Cell Rep 10 (2), 178-192 (2015)
   PUBMED   25578728
REFERENCE   5  (bases 1 to 1803)
  AUTHORS   Blasius,M., Wagner,S.A., Choudhary,C., Bartek,J. and Jackson,S.P.
  TITLE     A quantitative 14-3-3 interaction screen connects the nuclear
            exosome targeting complex to the DNA damage response
  JOURNAL   Genes Dev 28 (18), 1977-1982 (2014)
   PUBMED   25189701
REFERENCE   6  (bases 1 to 1803)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   7  (bases 1 to 1803)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   8  (bases 1 to 1803)
  AUTHORS   Lubas,M., Christensen,M.S., Kristiansen,M.S., Domanski,M.,
            Falkenby,L.G., Lykke-Andersen,S., Andersen,J.S., Dziembowski,A. and
            Jensen,T.H.
  TITLE     Interaction profiling identifies the human nuclear exosome
            targeting complex
  JOURNAL   Mol Cell 43 (4), 624-637 (2011)
   PUBMED   21855801
REFERENCE   9  (bases 1 to 1803)
  AUTHORS   Gustafson,M.P., Welcker,M., Hwang,H.C. and Clurman,B.E.
  TITLE     Zcchc8 is a glycogen synthase kinase-3 substrate that interacts
            with RNA-binding proteins
  JOURNAL   Biochem Biophys Res Commun 338 (3), 1359-1367 (2005)
   PUBMED   16263084
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Feb 1, 2022 this sequence version replaced XM_039081439.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ229819.1, SRR26360172.2701872.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760475 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-160               JAXUCZ010000008.1  57734674-57734833   c
            161-323             JAXUCZ010000008.1  57733507-57733669   c
            324-411             JAXUCZ010000008.1  57732905-57732992   c
            412-502             JAXUCZ010000008.1  57730583-57730673   c
            503-1803            JAXUCZ010000008.1  57728413-57729713   c
FEATURES             Location/Qualifiers
     source          1..1803
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q23"
     gene            1..1803
                     /gene="Rbm7"
                     /note="RNA binding motif protein 7"
                     /db_xref="GeneID:315634"
                     /db_xref="RGD:1308017"
     exon            1..160
                     /gene="Rbm7"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..862
                     /gene="Rbm7"
                     /note="isoform 1 is encoded by transcript variant 1;
                     RNA-binding protein 7"
                     /codon_start=1
                     /product="RNA-binding protein 7 isoform 1"
                     /protein_id="NP_001387934.1"
                     /db_xref="GeneID:315634"
                     /db_xref="RGD:1308017"
                     /translation="MGAAAAEADRTLFVGNLETKVTEELLFELFHQAGPVIKVKIPKD
                     KDGKLKQFAFVNFKHEVSVPYAMNLLNGIKLFGRPIKIQFRSGSSHLSQDASTSYPQH
                     HMGNLSPTSTSPNSYERTVGNVTPPAQMVQRSFSTPEDYQRQAVMNSVFRQMSYVGKF
                     GSPHADQLGFSPSVQPHGHTFNQSSSSQWRQDAVSSQRKRQNSHPYLADRHYSREQRY
                     SDHGSDYHYRGGREDFYYDDRNHDGWSHDYDNRRDSSRGGKWPSSRH"
     exon            161..323
                     /gene="Rbm7"
                     /inference="alignment:Splign:2.1.0"
     exon            324..411
                     /gene="Rbm7"
                     /inference="alignment:Splign:2.1.0"
     exon            412..502
                     /gene="Rbm7"
                     /inference="alignment:Splign:2.1.0"
     exon            503..1803
                     /gene="Rbm7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgcgcacta gggtcggtgg gccgcgagca gaccgcctag gcctgagact ggaacggcgc
       61 ggagatgggg gcggcggccg cggaggccga ccgcactctg ttcgtgggta acctggagac
      121 gaaggtgacg gaggagctcc tcttcgagct gttccaccag gctgggccag taataaaggt
      181 gaaaatccca aaagataaag atggcaaact gaagcagttt gcatttgtga atttcaaaca
      241 cgaagtgtct gttccctacg ccatgaatct tctcaatgga atcaaacttt tcgggaggcc
      301 tatcaaaatt cagtttagat caggaagtag tcacctctct caggacgcca gtacgtcata
      361 tccccagcac catatgggaa acttaagccc tacgtccaca tctcctaaca gctatgaaag
      421 gacggtgggt aacgtgactc cgccagcaca gatggtccag aggtcctttt caactccaga
      481 agattatcag cggcaagcag tgatgaacag tgttttcaga cagatgtcat atgttgggaa
      541 atttggttct ccacatgcag atcagttggg attttcaccg tcagttcaac cacatggtca
      601 cacctttaac cagtcttcca gctcccagtg gcgccaagat gcggtgtcat cacagcgtaa
      661 aagacagaat tctcacccct acctagcaga tagacactat agccgtgagc agcgctactc
      721 tgatcatggg tctgattatc attacagagg aggccgagag gatttctact atgacgacag
      781 gaatcatgat ggctggagcc atgattatga taacagaagg gacagtagta gaggtggaaa
      841 gtggccctca tcccgacact aacaagcatt ccaaggacat tgtttacagg gccattttcg
      901 gtccttttaa ctaagttgtt gcagaaatat ttctaaaaac tgtacagagt aatcccacaa
      961 ttttccacct gtctttgaaa aaaatgtttt taaacctagt aacagttcat agagaactga
     1021 gaaccgtggc tcctcgtgtg ctgctttaat cacctgacct cagggttctg atgaggaagg
     1081 tttatacaaa agagtgagca ccattctggt catttcagac agtctgggaa agatgagtat
     1141 gtagatgggt tgtattataa agcaaatatt ttacttatgt caccttttgt gttgcaagaa
     1201 atatcttggt aatgaatcaa cttggtgtat ataataggaa acatctaagt tggtagtctg
     1261 aaatggctgt ctgcattttg ttaataaatg agaaaatgga acttctcagt aatctgttta
     1321 ttaatagttt atttaagaca gtttattggc tttgcttgga gataaatcat attttctaac
     1381 tcagaattta agtacaaatt ctgtggtatg ctcttgaatt ttatcacaat tgaacatgtt
     1441 ataaatcttt tactagttca ttctaagaac tttaaaattc tttcattaag ctatatttga
     1501 tgtattacta gtcactcagg aagctcaata tatacaatgt atatttttac ataaaatgac
     1561 agtgttgatg aaaattattt tttagaaaga tgttaataca tagagaaaat ggcaaaatgt
     1621 ttcactggaa ggattataat tttgaaattt tgtttaacaa aacttccatg tttcaagatc
     1681 ctgttgttct tttcactgaa aaatcgtttt taagaattca ttcagagaaa aaaaatgtgg
     1741 attctcttta taccacagca tttatactat gttcctttta atgtattaaa tacacaaaaa
     1801 gaa
//
