LOCUS       NM_001415878            3048 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus RNA binding motif protein 28 (Rbm28), transcript
            variant 2, mRNA.
ACCESSION   NM_001415878
VERSION     NM_001415878.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3048)
  AUTHORS   Sloan,K.E., Mattijssen,S., Lebaron,S., Tollervey,D., Pruijn,G.J.
            and Watkins,N.J.
  TITLE     Both endonucleolytic and exonucleolytic cleavage mediate ITS1
            removal during human ribosomal RNA processing
  JOURNAL   J Cell Biol 200 (5), 577-588 (2013)
   PUBMED   23439679
REFERENCE   2  (bases 1 to 3048)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 3048)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643286.13245.1,
                                           SRR26643284.5696.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-182               JAXUCZ010000004.1  58726787-58726968   c
            183-341             JAXUCZ010000004.1  58723271-58723429   c
            342-436             JAXUCZ010000004.1  58722892-58722986   c
            437-512             JAXUCZ010000004.1  58722071-58722146   c
            513-605             JAXUCZ010000004.1  58721397-58721489   c
            606-677             JAXUCZ010000004.1  58719936-58720007   c
            678-855             JAXUCZ010000004.1  58718001-58718178   c
            856-992             JAXUCZ010000004.1  58717769-58717905   c
            993-1065            JAXUCZ010000004.1  58714934-58715006   c
            1066-1175           JAXUCZ010000004.1  58706797-58706906   c
            1176-1249           JAXUCZ010000004.1  58702417-58702490   c
            1250-1385           JAXUCZ010000004.1  58701524-58701659   c
            1386-1450           JAXUCZ010000004.1  58700549-58700613   c
            1451-1609           JAXUCZ010000004.1  58698534-58698692   c
            1610-1759           JAXUCZ010000004.1  58695582-58695731   c
            1760-1834           JAXUCZ010000004.1  58695218-58695292   c
            1835-2088           JAXUCZ010000004.1  58692212-58692465   c
            2089-2191           JAXUCZ010000004.1  58691558-58691660   c
            2192-3048           JAXUCZ010000004.1  58688337-58689193   c
FEATURES             Location/Qualifiers
     source          1..3048
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q22"
     gene            1..3048
                     /gene="Rbm28"
                     /note="RNA binding motif protein 28"
                     /db_xref="GeneID:312182"
                     /db_xref="RGD:1311336"
     exon            1..182
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..2326
                     /gene="Rbm28"
                     /note="isoform 2 is encoded by transcript variant 2;
                     RNA-binding protein 28"
                     /codon_start=1
                     /product="RNA-binding protein 28 isoform 2"
                     /protein_id="NP_001402807.1"
                     /db_xref="GeneID:312182"
                     /db_xref="RGD:1311336"
                     /translation="MAGLTLFVGRLPPSARSDQLEELFSQVGPVKQCFVVTEKGSKAC
                     RGFGYVTFSMLEDVQRALKEITTFEGCKINVTIAKKKLKNKSKETRKNENSESPKKEP
                     KHKKAKVADKKARLIIRNLSFKCSEDDLKSVFTHYGTVLEVNIPRKPDGKMRGFAFIQ
                     FKNLLEAGKALKGANMKEIKGRTVAVDWAVAKDKYKDAQHTSVSGGKKSSERKPKESS
                     KKSCRVEEQVEDDDDDGEDEEDDDTQDDEDESRDSTVASPVSVRKRAVKRAAPEESTE
                     EDTYDDSDLEEGSSSYGDGTAHSESSTEELEDEDVPVSKKKKRKLPSDVTEGKTVFIR
                     NLSFDSEEEALGEVLQQFGDLKYVRIVLHPDTEHSKGCAFAQFVTQEAAQKCLAAASP
                     ETEGGGLKLDGRQLKVDLAVTRDEAAKLQTKKVKKPTGTRNLYLAREGLIRAGTKAAE
                     GVSAADMAKRERFELLKHQKLKNQNIFVSQTRLCLHNLPKSVDDKQLRKLLLQATGGE
                     KGVRIKECRVMRDLKAVHGKMKGQSLGYAFVEFQKHEHALRALRHFNNNPETFGPQKR
                     PIVEFSLEDRRKLKVKELRIQRSLQKMGSKPVTSKPQKEQKEQGKDKQQKAAQGGTRD
                     QSKAPGEQGKGRCTSWTGFQTKAEVEQVELPDGTRRRKVLALPSHRGPKVRLRDRGKV
                     KSLPSKKPKPQMGQRKQKKQQSASSLQAPKKKAKESKAEAHFNRLVEQYKQKLLGPSK
                     GASLVKRSKWFDS"
     exon            183..341
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            342..436
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            437..512
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            513..605
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            606..677
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            678..855
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            856..992
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            993..1065
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1175
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1249
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1385
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            1386..1450
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            1451..1609
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            1610..1759
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            1760..1834
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..2088
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            2089..2191
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
     exon            2192..3048
                     /gene="Rbm28"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacccagcgg tcgctcgcgc cggtgctggt tgcgcgtggt ctcacacgct tgtttctcgg
       61 tctcatggcc ggtctgactc tattcgtggg ccgtctcccg ccctccgctc gcagtgatca
      121 gctggaagag ctgttcagtc aggtgggtcc ggtgaaacag tgcttcgtgg tgacagagaa
      181 agggagtaaa gcatgccggg gctttggcta tgtgaccttc tccatgctgg aagatgttca
      241 gagggccctt aaggagatca ctaccttcga aggttgcaag atcaatgtga ccattgccaa
      301 gaaaaaactg aagaacaagt ccaaggaaac aaggaaaaat gaaaattcag agtccccaaa
      361 aaaggagcca aagcacaaaa aagccaaagt ggcagataag aaagccagat taattatccg
      421 gaacctcagc tttaagtgtt cagaagatga cttgaaatca gtatttactc actatggaac
      481 tgttctggaa gtgaatatcc caaggaaacc agatggaaag atgcgtggtt ttgcttttat
      541 tcaattcaaa aacctccttg aagcaggaaa agctctcaaa ggcgcaaata tgaaagagat
      601 aaaagggcgg actgtggctg tggactgggc tgtggccaag gacaaataca aagatgccca
      661 gcatacttct gtctcaggtg gaaagaagag cagcgagcgt aagcctaagg agtcgagtaa
      721 gaagagctgc agggtggaag agcaagtaga agatgatgat gatgatggtg aagatgaaga
      781 agatgatgat acccaagatg atgaggacga aagtagagac tcgacggtag cttctcctgt
      841 gagcgtgcgg aagagagcag tcaagagagc agctcccgag gaaagcaccg aggaagacac
      901 ttacgatgac agcgatctgg aggaagggag cagctcctac ggcgacggga cggcacacag
      961 cgagagcagc actgaagagc tggaggacga agatgttcca gtctcaaaga aaaagaagag
     1021 gaagttaccc tccgatgtga ctgaagggaa aactgtcttc atcagaaatc tttcatttga
     1081 ctcagaagag gaagcgcttg gggaggtcct ccagcaattt ggtgatctta agtatgtccg
     1141 gattgtcttg catccagaca cagagcattc taaaggttgt gcatttgcac aattcgtgac
     1201 tcaggaagca gctcagaaat gccttgcagc agcttctcca gagaccgagg gtggtgggct
     1261 taaactggat ggccggcagc tcaaggtcga cttggctgtg acccgtgatg aggcagcaaa
     1321 gcttcagaca aagaaggtga agaagccaac tggaacgcgg aacctctatc tggcccgaga
     1381 aggcttgatc cgcgctggga cgaaggctgc tgagggtgtg agtgccgcag acatggccaa
     1441 acgcgagcgg tttgagctac tgaaacatca gaaactcaag aaccagaata tctttgtctc
     1501 ccagaccagg ctttgcctgc acaacctccc gaagtcagtg gatgataaac agctaaggaa
     1561 gctgctgctg caggccactg gaggagagaa gggggttcgc attaaggagt gtagagtgat
     1621 gcgagaccta aaggcagttc atggaaaaat gaagggtcag tccctgggct atgcctttgt
     1681 ggagttccaa aagcatgagc atgccctccg agccctccgc cacttcaaca acaacccgga
     1741 gacctttggg ccccagaaga gaccaatagt ggagttctct ttagaagatc gaaggaaact
     1801 taaagtaaag gagctgagaa tccagcgcag cctgcaaaaa atgggatcta agcctgtgac
     1861 cagtaagccc caaaaggaac agaaagaaca aggaaaagac aagcaacaga aagcagctca
     1921 gggcggcacg cgggatcaga gtaaggcgcc tggagagcag gggaagggcc gctgcacctc
     1981 gtggacaggg ttccagacca aggccgaggt ggagcaggtg gagctccccg acgggacaag
     2041 gagaagaaag gtcctggcgc tcccttcaca ccgaggcccc aaagtgaggc tgcgggacag
     2101 aggcaaagtg aagtcccttc cttctaagaa gccaaagccc cagatgggcc agcggaagca
     2161 aaagaagcag cagtcagctt cttccctgca ggcacctaag aaaaaagcta aagaaagtaa
     2221 ggcagaagcc cacttcaacc gactggttga acaatataag cagaagttgt tgggcccttc
     2281 taaaggagca tcccttgtga agagaagcaa atggtttgac agctgatcgt gcctgcagcc
     2341 tgtaagaaag ccatgtcttt cactgaggaa aggatcctag atgataccca ctttcttggg
     2401 gactctgtgg gttgtctaca ttcttggtcc gttctccagt gtggtgtttg ttagccacaa
     2461 ggaaacacct gaaaagcacc atgaaggttt ctaacttaac cgtcttagtg ctaaatctgc
     2521 acatgtaatt gcaactgatt tctaatctct tctcagatgg aaactattgt aaagagtgtc
     2581 ccagagtact gaattttaaa gatgcatatt ttgttatgga gtctgtaagt gagaaattgt
     2641 gactttttgg atgtgtctca tttttaatat acacaaatat attatttatg agtttttcta
     2701 aaagaacctt tttaacattt ttaatcggtt acagagtttg cacaactagg agcagagaaa
     2761 atgcttacta aagtagtctt gagtgctgga gatgccaggg aaggactgaa ggccgtccgt
     2821 ctggcatcag gcagcacctg agaactgtct gtccctggcg gaggggctaa ctggagatat
     2881 ggttgcgggc tgggcaccag cctgaccaca catggcccag atgtgcccct cagcaccttc
     2941 tcccagggac tgagctctct ggtgagggaa ggcagtgggc acgaggctct gacctatggg
     3001 cctgaagtct tacctggtcc tgcaaaataa acagtttaac cacatgga
//
