LOCUS       NM_001395131            4200 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus RNA binding motif protein 25 (Rbm25), mRNA.
ACCESSION   NM_001395131 XM_039112646
VERSION     NM_001395131.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4200)
  AUTHORS   Tian,X., Zhou,G., Li,H., Zhang,X., Zhao,L., Zhang,K., Wang,L.,
            Liu,M., Liu,C. and Yang,P.
  TITLE     RBM25 binds to and regulates alternative splicing levels of
            Slc38a9, Csf1, and Coro6 to affect immune and inflammatory
            processes in H9c2 cells
  JOURNAL   PeerJ 11, e16312 (2023)
   PUBMED   37953772
  REMARK    GeneRIF: RBM25 binds to and regulates alternative splicing levels
            of Slc38a9, Csf1, and Coro6 to affect immune and inflammatory
            processes in H9c2 cells.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4200)
  AUTHORS   Zhu,Z., Pu,J., Li,Y., Chen,J., Ding,H., Zhou,A. and Zhang,X.
  TITLE     RBM25 regulates hypoxic cardiomyocyte apoptosis through
            CHOP-associated endoplasmic reticulum stress
  JOURNAL   Cell Stress Chaperones 28 (6), 861-876 (2023)
   PUBMED   37736860
  REMARK    GeneRIF: RBM25 regulates hypoxic cardiomyocyte apoptosis through
            CHOP-associated endoplasmic reticulum stress.
REFERENCE   3  (bases 1 to 4200)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 4200)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 4200)
  AUTHORS   Zhou,A., Ou,A.C., Cho,A., Benz,E.J. Jr. and Huang,S.C.
  TITLE     Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site
            selection
  JOURNAL   Mol Cell Biol 28 (19), 5924-5936 (2008)
   PUBMED   18663000
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Jun 4, 2021 this sequence version replaced XM_039112646.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.36365.1,
                                           SRR26360190.873232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-167               JAXUCZ010000006.1  109002891-109003057
            168-288             JAXUCZ010000006.1  109012663-109012783
            289-338             JAXUCZ010000006.1  109014718-109014767
            339-506             JAXUCZ010000006.1  109016477-109016644
            507-564             JAXUCZ010000006.1  109017637-109017694
            565-722             JAXUCZ010000006.1  109020303-109020460
            723-908             JAXUCZ010000006.1  109027846-109028031
            909-962             JAXUCZ010000006.1  109028713-109028766
            963-1046            JAXUCZ010000006.1  109028984-109029067
            1047-1327           JAXUCZ010000006.1  109032355-109032635
            1328-1538           JAXUCZ010000006.1  109035809-109036019
            1539-1628           JAXUCZ010000006.1  109036131-109036220
            1629-1702           JAXUCZ010000006.1  109039989-109040062
            1703-1853           JAXUCZ010000006.1  109040839-109040989
            1854-2178           JAXUCZ010000006.1  109042401-109042725
            2179-2453           JAXUCZ010000006.1  109043104-109043378
            2454-2552           JAXUCZ010000006.1  109044248-109044346
            2553-2600           JAXUCZ010000006.1  109045995-109046042
            2601-4200           JAXUCZ010000006.1  109048560-109050159
FEATURES             Location/Qualifiers
     source          1..4200
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q31"
     gene            1..4200
                     /gene="Rbm25"
                     /note="RNA binding motif protein 25"
                     /db_xref="GeneID:366693"
                     /db_xref="RGD:1308755"
     exon            1..167
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            168..288
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     CDS             183..2693
                     /gene="Rbm25"
                     /codon_start=1
                     /product="RNA-binding protein 25"
                     /protein_id="NP_001382060.1"
                     /db_xref="GeneID:366693"
                     /db_xref="RGD:1308755"
                     /translation="MSFPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPGTPMIPVPM
                     SIMAPAPTVLVPTVSMVGKHLGARKDHPGLKLKENDENCGPTTTVFVGNISEKASDML
                     IRQLLAKCGLVLSWKRVQGASGKLQAFGFCEYKEPESTLRALRLLHDLQIGEKKLLVK
                     VDAKTKAQLDEWKAKKKANGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYS
                     SELNAPSQESDSHPRKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLI
                     SREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERERER
                     EKEKERERERERDRDRDRTKERDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERER
                     EREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAY
                     QERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG
                     SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRR
                     QPQIKQEPESEEEEEEKQEKEEKREEPVEEEEEPEQKPCLKPTLRPISSAPSVSSASG
                     NATPNTPGDESPCGIIIPHENSPDQQQPEEHRPKIGLSLKLGASNSPGQPNSVKRKKL
                     PVDSVFNKFEDEDSDDVPRKRKLVPLDYGEDDKNAAKGTVNTEEKRKHIKSLIEKIPT
                     AKPELFAYPLDWSIVDSILMERRIRPWINKKIIEYIGEEEATLVDFVCSKVMAHSSPQ
                     SILDDVAMVLDEEAEVFIVKMWRLLIYETEAKKIGLVK"
     exon            289..338
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            339..506
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            507..564
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            565..722
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            723..908
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            909..962
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1046
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1327
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1538
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1628
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            1629..1702
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            1703..1853
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            1854..2178
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            2179..2453
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            2454..2552
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            2553..2600
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
     exon            2601..4200
                     /gene="Rbm25"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctccagtag ctccccgcgc agcgcggctg tgtttgcggc ctattcgagt aggcgcttcg
       61 gaaccagtct ctgagtcggg cggcgcgcag aaacctccaa ccggtggagc ctactcataa
      121 cctgacgccc agaggccgcg aagacagtac cgttttctta gcggcggact ggtgcagtca
      181 gaatgtcttt tccccctcat ttgaatcgcc ctcccatggg aatcccagct ctccctccgg
      241 ggatcccacc cccacagttt cctggctttc ctccaccagt acctccaggg acaccaatga
      301 ttcctgtacc aatgagtatt atggctcctg ctccaactgt cctagtgcct accgtgtcca
      361 tggttggaaa gcatttggga gcaagaaagg atcatccagg cttaaaatta aaagaaaatg
      421 atgaaaattg tggccctact actacagttt ttgttggcaa catttctgag aaggcctcag
      481 acatgcttat aagacagctc ttagctaaat gtggtttggt gttgagctgg aagagagtgc
      541 aaggcgcttc tggaaaactt caagcgtttg gattttgtga gtataaagag cctgaatcta
      601 ccctccgagc cctcagatta ttgcatgacc ttcagattgg agagaagaag ctacttgtta
      661 aagttgatgc aaagacaaag gcgcagttgg atgaatggaa agcaaagaag aaagctaatg
      721 ggaacgcaag accagaaact gtcactaatg atgatgaaga agccttagat gaagaaacaa
      781 agcgaagaga ccagatgatt aaaggggcca ttgaagtttt aatccgagaa tattccagtg
      841 agctaaatgc cccctcacag gagtctgact ctcaccccag gaagaagaaa aaggaaaaga
      901 aggaggacat tttccgtaga tttccagtgg ccccattgat cccttaccca ctcatcacca
      961 aggaggatat aaatgctata gaaatggaag aagacaaaag agatttgata tcccgagaga
     1021 tcagcaagtt cagagacaca cacaagaaac tggaagaaga gaaaggcaaa aaagaaaaag
     1081 aaagacagga aattgagaaa gaacggagag aaagagagag ggaacgtgaa agggaacgag
     1141 aaaggcgaga acgggaacga gaaagggaaa gagaacgtga acgagaaaag gaaaaagaac
     1201 gggagcggga acgagaacgg gatagggatc gtgaccgcac aaaagagcga gaccgagacc
     1261 gagagagaga tcgggaccgg gaccgagaaa ggagctcaga tcgaaataag gatcggagtc
     1321 gatcaagaga aaaaagtaga gatcgtgaaa gggaacggga acgggagcga gagagagaac
     1381 gggagagaga acgggagaga gagagagaac gggagagaga acgggagcgt gaaagagaga
     1441 aagacaagaa aagagacaga gaagaggatg aagaagatgc atatgaacga agaaaacttg
     1501 aaagaaaact gcgagagaaa gaggctgcgt atcaagagcg ccttaagaat tgggaaatca
     1561 gagaacgaaa gaaaactagg gaatatgaga aggaggcgga aagagaagaa gaaagaagaa
     1621 gagaaatggc taaagaggct aaacgattaa aagaattcct agaagattat gacgatgaca
     1681 gagatgaccc aaagtactac aggggtagtg ctcttcagaa acggttgcgt gatagggaga
     1741 aagaaatgga agccgatgaa cgagacagga agagagagaa ggaagaactt gaggaaatca
     1801 ggcaacgttt actggcagag gggcatccag atccagatgc agagctccag aggatggaac
     1861 aagaggctga gaggcgcagg caacctcaaa taaagcaaga gccagagtca gaggaagaag
     1921 aagaagaaaa gcaagaaaaa gaagaaaaac gagaggagcc tgtggaagag gaagaagaac
     1981 cagagcaaaa gccttgtctc aaacccacct tgagacccat cagctccgct ccatctgtgt
     2041 cctctgccag cggcaatgca acacctaaca ctcccgggga cgagtctcct tgtggtatta
     2101 ttattcctca tgaaaactca ccagatcaac agcagcctga ggaacatagg ccaaaaatag
     2161 gactaagtct taaattgggt gcttccaata gtcctggcca acctaattca gtgaagagaa
     2221 agaaactacc tgtagatagt gtctttaaca aatttgagga tgaagacagt gatgatgtgc
     2281 cccgaaaaag gaaactggtt cccctggatt atggcgaaga tgataaaaat gccgccaaag
     2341 gcactgtaaa cactgaagaa aagcgcaaac acattaagag tctcattgag aaaattccca
     2401 cagccaagcc tgagctcttt gcttatcctt tggattggtc tattgtggat tctatactga
     2461 tggaacgcag aatccggcca tggatcaata agaaaatcat agaatacata ggtgaagaag
     2521 aagctacttt agttgatttt gtttgttcta aggttatggc acatagttca ccacagagca
     2581 ttttagatga tgttgccatg gtactagatg aagaagcaga agtttttata gtcaaaatgt
     2641 ggcgattatt gatatatgaa acagaagcca agaaaattgg tcttgtgaag taaacttttt
     2701 acactcagag ttacatttca gatttcttct ttcacaccct tcaaaggact tggaattttc
     2761 tgtgtcttca aagacatttg tgagatctgt aattttttta atgtagaaaa tgtgaattct
     2821 tttgtcctct aatttgttga tgctgtgtac tcacttggtt gtaaagccat ctgtgtcctt
     2881 ggttctcttt atacaccagg cacagattac tggtgtgttt tgtaagctgc agctactgta
     2941 cacagcctat ttgatagaat cttgttctgc tgattcgttc cctgtaaata ttaaaatggc
     3001 tccccaattc ttttgcagaa ttctacttaa tattaaaact gtattgtata ggcgccaaca
     3061 tgaataagtt gaatactagt cacacccatt acagtctcat ccccacgtcc ctcatcagaa
     3121 atgacaagca agctcttgta aaggcatgga gtttaaaatt agattgcaaa acctagcaga
     3181 cagttcattc ctaatgtatc tctgtattaa tgtgtttatg tgaatgtatg tataaaagtc
     3241 ttttttaaaa tttttttggt gggctccctt aaacatttcg taattcatca atatactcat
     3301 aaaagaaaag taattattgt gccaacccaa ataactagga taattatggt gtgtttccca
     3361 gaggctggta ttctgcagtg agcaaccagc tttgtgttct tctgtgaata ggatgataca
     3421 tcataatctt aaccctccct taatttgatg gctcacaatt gaagcaaagg ctaaaagtct
     3481 ggagcatttt actcaataca ttttcaacta actctaaatc tttatttaat tttggtgtat
     3541 tcattttaat aaaacaattc caaaagtata agggagggga ggagctcacc ttctttttaa
     3601 agcaaatgac cagggattac ctcagtgggc gagcttatgc ttagcatgta agggcctggg
     3661 gtctgttccc agcaacaata aacgagtaac taaggtaagt ttacaaaaga gatttgaccg
     3721 aacacagtag taattcaccg tggtagttaa atgtttacat ctttcttcca aagatacacc
     3781 attaaagaca ggtttctgct cacaacgttt tattactggt catcaagctt tagctgtatt
     3841 gatgacaaat cggctttatt agtaattcag aagatcacca ggggcaaaat ttatttgaaa
     3901 attactaagt tctaaacagc tctgccaaca gagtaggtgt ggctgttgcc atgtttgctt
     3961 attaataaga taaagactgg attgttagaa taatgtaact gtgagcttga gttactaggt
     4021 tgttttgttt tttgttttgt attttttttt aaacattcga gaggacatcc aaaacactgt
     4081 tcttaatgtt gaaccttgac atggcttcat tatgtaaata tttcagttat taaaaatgta
     4141 tatatttgat cttggagatg ctttctttga gtcttgtaaa taaatgacat tatgttataa
//
