LOCUS       NM_001107611            6682 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus RNA binding motif protein 20 (Rbm20), mRNA.
ACCESSION   NM_001107611 XM_001062355 XM_220079
VERSION     NM_001107611.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6682)
  AUTHORS   Larson,E.J., Gregorich,Z.R., Zhang,Y., Li,B.H., Aballo,T.J.,
            Melby,J.A., Ge,Y. and Guo,W.
  TITLE     Rbm20 ablation is associated with changes in the expression of
            titin-interacting and metabolic proteins
  JOURNAL   Mol Omics 18 (7), 627-634 (2022)
   PUBMED   35762193
  REMARK    GeneRIF: Rbm20 ablation is associated with changes in the
            expression of titin-interacting and metabolic proteins.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6682)
  AUTHORS   Zhang,Y., Wang,C., Sun,M., Jin,Y., Braz,C.U., Khatib,H.,
            Hacker,T.A., Liss,M., Gotthardt,M., Granzier,H., Ge,Y. and Guo,W.
  TITLE     RBM20 phosphorylation and its role in nucleocytoplasmic transport
            and cardiac pathogenesis
  JOURNAL   FASEB J 36 (5), e22302 (2022)
   PUBMED   35394688
  REMARK    GeneRIF: RBM20 phosphorylation and its role in nucleocytoplasmic
            transport and cardiac pathogenesis.
REFERENCE   3  (bases 1 to 6682)
  AUTHORS   Maimaiti,R., Zhu,C., Zhang,Y., Ding,Q. and Guo,W.
  TITLE     RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity and
            Differential Hormonal Responses between Muscles and in Muscle Cell
            Cultures
  JOURNAL   Int J Mol Sci 22 (6), 2928 (2021)
   PUBMED   33805770
  REMARK    GeneRIF: RBM20-Mediated Pre-mRNA Splicing Has Muscle-Specificity
            and Differential Hormonal Responses between Muscles and in Muscle
            Cell Cultures.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6682)
  AUTHORS   Schwahn,D.J., Pleitner,J.M. and Greaser,M.L.
  TITLE     Megaesophagus Is a Major Pathological Condition in Rats With a
            Large Deletion in the Rbm20 Gene
  JOURNAL   Vet Pathol 57 (1), 151-159 (2020)
   PUBMED   31221019
  REMARK    GeneRIF: Megaesophagus Is a Major Pathological Condition in Rats
            With a Large Deletion in the Rbm20 Gene.
REFERENCE   5  (bases 1 to 6682)
  AUTHORS   Morinaga,A., Ito,J., Niimi,T. and Maturana,A.D.
  TITLE     RBM20 Regulates CaV1.2 Surface Expression by Promoting Exon 9*
            Inclusion of CACNA1C in Neonatal Rat Cardiomyocytes
  JOURNAL   Int J Mol Sci 20 (22), 5591 (2019)
   PUBMED   31717392
  REMARK    GeneRIF: RBM20 specifically regulates the inclusion of exon 9* in
            CACNA1C mRNA, resulting in reduced cell-surface membrane expression
            of l-channels in cardiomyocytes.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6682)
  AUTHORS   Maatz,H., Jens,M., Liss,M., Schafer,S., Heinig,M., Kirchner,M.,
            Adami,E., Rintisch,C., Dauksaite,V., Radke,M.H., Selbach,M.,
            Barton,P.J., Cook,S.A., Rajewsky,N., Gotthardt,M., Landthaler,M.
            and Hubner,N.
  TITLE     RNA-binding protein RBM20 represses splicing to orchestrate cardiac
            pre-mRNA processing
  JOURNAL   J Clin Invest 124 (8), 3419-3430 (2014)
   PUBMED   24960161
  REMARK    GeneRIF: combined transcriptome-wide crosslinking
            immunoprecipitation, RNA-seq, and quantitative proteomics in cell
            culture and hearts to examine how RBM20 regulates alternative
            splicing in the heart
REFERENCE   7  (bases 1 to 6682)
  AUTHORS   Guo,W., Pleitner,J.M., Saupe,K.W. and Greaser,M.L.
  TITLE     Pathophysiological defects and transcriptional profiling in the
            RBM20-/- rat model
  JOURNAL   PLoS One 8 (12), e84281 (2013)
   PUBMED   24367651
  REMARK    GeneRIF: new insights on Rbm20 function and how its malfunction
            leads to cardiomyopathy
            Publication Status: Online-Only
REFERENCE   8  (bases 1 to 6682)
  AUTHORS   Li,S., Guo,W., Dewey,C.N. and Greaser,M.L.
  TITLE     Rbm20 regulates titin alternative splicing as a splicing repressor
  JOURNAL   Nucleic Acids Res 41 (4), 2659-2672 (2013)
   PUBMED   23307558
REFERENCE   9  (bases 1 to 6682)
  AUTHORS   Guo,W., Schafer,S., Greaser,M.L., Radke,M.H., Liss,M.,
            Govindarajan,T., Maatz,H., Schulz,H., Li,S., Parrish,A.M.,
            Dauksaite,V., Vakeel,P., Klaassen,S., Gerull,B., Thierfelder,L.,
            Regitz-Zagrosek,V., Hacker,T.A., Saupe,K.W., Dec,G.W.,
            Ellinor,P.T., MacRae,C.A., Spallek,B., Fischer,R., Perrot,A.,
            Ozcelik,C., Saar,K., Hubner,N. and Gotthardt,M.
  TITLE     RBM20, a gene for hereditary cardiomyopathy, regulates titin
            splicing
  JOURNAL   Nat Med 18 (5), 766-773 (2012)
   PUBMED   22466703
  REMARK    GeneRIF: Deep sequencing of the human and rat cardiac transcriptome
            revealed an RBM20-dependent regulation of alternative splicing
REFERENCE   10 (bases 1 to 6682)
  AUTHORS   Brauch,K.M., Karst,M.L., Herron,K.J., de Andrade,M., Pellikka,P.A.,
            Rodeheffer,R.J., Michels,V.V. and Olson,T.M.
  TITLE     Mutations in ribonucleic acid binding protein gene cause familial
            dilated cardiomyopathy
  JOURNAL   J Am Coll Cardiol 54 (10), 930-941 (2009)
   PUBMED   19712804
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EU562301.1.
            
            On Aug 15, 2009 this sequence version replaced NM_001107611.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU562301.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760384, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6682              EU562301.1         1-6682
FEATURES             Location/Qualifiers
     source          1..6682
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..6682
                     /gene="Rbm20"
                     /note="RNA binding motif protein 20"
                     /db_xref="GeneID:309544"
                     /db_xref="RGD:1307427"
     exon            1..293
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     CDS             103..3726
                     /gene="Rbm20"
                     /note="probable RNA-binding protein 20"
                     /codon_start=1
                     /product="RNA-binding protein 20"
                     /protein_id="NP_001101081.2"
                     /db_xref="GeneID:309544"
                     /db_xref="RGD:1307427"
                     /translation="MVLAAAMSQDADPSGPEQPDRDACIVPGVQGPPAPQGQQGMQPL
                     PPPLPPPPQPQSSLPQIIQNAAKLLDKNPFSVSSQNPLLTSPASVQLAQIQAQLTLHR
                     LKMAQTAVTNNTAAATVLNQVLSKVAMSQPLFNQLRHPSVLGTTHGPTGVSQHAATVP
                     SAHFPSTAIAFSPPSQAGGPGPSVSLPSQPPNAMVVHTFSGVVPQTPAQPAVILSIGK
                     AGPTPATTGFYDYGKANPGQAYGSETEGQPGFLPASASAAASGGVTYEGHYSHTGQDG
                     QATFSKDFYGPSAQGSHAAGGFPADQAGSMKGDVGGLLQGTNSQWERPSGFSGQNKAD
                     ITAGPGLWAPPASQPYELYDPEEPTSDRAPPAFGSRLNNSKQGFNCSCRRTKEGQAML
                     SVRPLQGHQLNDFRGLAPLHLPHICSICDKKVFDLKDWELHVKGKLHAQKCLLFSESA
                     GLRSICATGEGTLSASANSTAVYNPTGNEDYTSTLGTSYAAIPTRAFAQSNPMFPSAS
                     SGTNFAQRKGAGRVVHICNLPEGSCTENDVINLGLPFGKVTNYILMKSTNQAFLEMAY
                     TEAAQAMVQYYQEKPALINGEKLLIRMSTRYKELQLKKPGKNVAAIIQDIHSQRERCM
                     LREADRYGPERPRSRSPMSRSLSPRSHSPPGPSRADWGNGRDSYAWRDEDRETVPRRE
                     NGEDKRDRLDVWAHDRKHYPRQLDKAELDERLEGGRGYREKYLKSGSPGPLHSASGYK
                     GREDGYHRKETKAKLDKHPKQQQQDVPGRSRRKEEARLREPRHPHPEDSGKEEDLEPK
                     VTRAPEGTKSKQSEKSKTKRADRDQEGADDKKEGRGAENEAGTEEQEGMEESPASVGT
                     QQEGTESSDPENTRTKKGQDCDSGSEPEGDNWYPTNMEELVTVDEVGEEDFIMEPDIP
                     ELEEIVPIDQKDKILPEICPCVTATLGLDLAKDFTKQGETLGNGDAELSPKLPGQVPS
                     TSTSCPNDTDMEMAGLNLDAERKPAESETGLSPEVSNCYEKEARGAEGSDVRLAPAAQ
                     RMSSPQPADERARQSSPFLDDCKARGSPEDGPHEVSPLEEKASPTTESDLQSQACQEN
                     SRYTETRSLNSRSPEFTEAELKEPLSLPSWEPEVFSELSIPLGVEFVVPRTGFYCKLC
                     GLFYTSEEAAKVSHCRSTVHYRNLQKYLSQLAEEGLKETEGVDSPSPERSGIGPHLER
                     KKL"
     exon            294..1386
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            1387..1448
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            1449..1540
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            1541..1638
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..1779
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            1780..1911
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..1991
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            1992..2616
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            2617..2721
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            2722..3361
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            3362..3493
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            3494..3615
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
     exon            3616..6682
                     /gene="Rbm20"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaggggactg ggtacaggga ccccggccag tgagcgcctg tgttccggga ccgcccctcc
       61 ctcgcgctct ttcgctgcga gcccgggtcg gtgtcgccgc gcatggtgct ggctgcagcc
      121 atgagccaag acgcggatcc cagcggtccg gagcaacccg acagagatgc ctgcattgtg
      181 cctggtgttc aagggccccc tgcgccccaa ggccagcaag ggatgcagcc cctgccgcca
      241 ccgctaccgc caccgcctca gcctcaatcc agcctgcccc agatcatcca aaatgctgcc
      301 aagctcctgg acaagaaccc tttctccgtc agtagccaga accctctgct cacttcgcca
      361 gccagcgtcc agctggccca gatacaggcc cagctcaccc tccatcggct gaagatggca
      421 cagaccgcag tcaccaacaa cactgcagcc gccactgtcc tcaaccaagt cctctccaaa
      481 gtggccatgt cccagcctct cttcaaccag cttcgccatc cgtctgtgct tggcaccaca
      541 catggcccta ctggggtctc ccagcatgct gccaccgttc ccagtgctca ctttccctca
      601 actgcaatcg ccttttcgcc cccaagccag gcaggaggcc cggggccttc tgtgagcctc
      661 cccagccagc cccccaatgc tatggtagtg cataccttca gtggggtggt gcctcagacc
      721 cctgcccagc cagcagtcat cctaagcatt gggaaggcgg ggccgacacc tgctactaca
      781 gggttctatg actatggcaa agccaaccct ggccaggcct atggttctga aacggagggc
      841 cagccgggct tcttgccagc ctcggcgtca gccgcagcat caggcggtgt gacctatgaa
      901 ggacactata gccacacagg gcaggatggc caagccacct tttctaaaga cttctatgga
      961 cccagtgccc aagggtcaca tgcagcaggt gggttcccag ctgatcaggc tgggagcatg
     1021 aaaggagacg tcggtgggtt gttgcaaggt accaacagcc agtgggagag gccctctggg
     1081 ttctctggcc agaacaaggc cgatattaca gccgggcccg gtttgtgggc tccacctgcc
     1141 agtcagcctt atgaactata tgatcctgag gagcctacct cagacagggc ccctcctgcc
     1201 tttggatctc gacttaacaa cagcaagcag ggattcaact gctcctgccg gcggacaaag
     1261 gaggggcagg ccatgctgtc cgtgaggccc ctgcagggtc atcaactgaa tgacttccga
     1321 ggcttggctc cactccacct tccacatatc tgcagcatct gtgacaagaa ggtgtttgac
     1381 ctgaaggact gggagctaca tgtgaagggg aagttgcatg cccagaaatg cctgctcttc
     1441 tcagaaagtg ctggcctccg gagtatatgt gctacaggag aagggacgct gtctgcctct
     1501 gcaaacagca cagctgttta taaccccact ggaaatgagg attatacctc aactcttgga
     1561 acatcatatg cagccattcc aacaagggcc tttgctcaat caaaccccat gtttccttcg
     1621 gcttcctctg ggacaaattt tgcacagagg aaaggtgctg gacgagttgt gcacatctgc
     1681 aatctcccag agggcagctg cacggagaat gacgtcatca acctggggct gccctttggc
     1741 aaggtcacta attacatcct tatgaagtca actaatcagg ctttcttgga gatggcttac
     1801 acagaagctg ctcaagctat ggtccagtac taccaagaaa agcccgcgct tatcaatggc
     1861 gagaagttac tcattcggat gtccacgaga tacaaggaat tgcagctgaa gaaacctggg
     1921 aaaaatgtgg ctgctatcat ccaggacatc cactcccaaa gggagaggtg catgctccgg
     1981 gaagctgaca gatatggtcc agagcgacca cgttctcgaa gtccaatgag ccgatcgctc
     2041 tccccgagat cccacagtcc tcctggcccc tctcgggctg attggggcaa tggccgtgac
     2101 tcctacgcat ggagggacga ggatcgggag acggtgccca ggagggagaa cggggaagac
     2161 aagagggaca ggttggatgt ttgggcacat gaccggaaac actatcccag gcagctggac
     2221 aaagccgagt tggatgagcg actcgaagga gggaggggct accgggaaaa gtacttgaag
     2281 tcagggtccc ccggcccact ccattctgcg tctggctaca aaggccggga agatggctac
     2341 catcgaaaag agactaaagc taagttggac aaacacccaa agcagcagca gcaggatgtg
     2401 ccaggaagat ccaggaggaa agaagaggcg cgactacggg agcccagaca ccctcaccca
     2461 gaggactctg gcaaggaaga ggatctggag cccaaggtca ctcgggcccc cgagggtacc
     2521 aagtccaagc aaagtgagaa aagtaaaacc aagagagccg acagagacca agaaggagct
     2581 gatgacaaaa aagaaggccg aggggcagag aatgaggctg ggactgagga acaggaaggc
     2641 atggaagaga gccccgcatc ggtgggcaca cagcaggaag ggacggagtc ctccgatcca
     2701 gaaaacacaa ggacaaagaa gggacaagac tgtgacagtg gaagtgagcc tgagggggac
     2761 aactggtacc ccaccaacat ggaggagctg gtcacagtgg acgaagtagg ggaggaagac
     2821 ttcatcatgg agccagacat accggagctg gaagaaattg tacccatcga ccagaaagac
     2881 aaaatcctcc ccgaaatatg tccctgtgta acagccacct taggtttgga cttggccaaa
     2941 gacttcacca agcagggaga gaccctaggg aacggagacg cagaactcag cccgaagctg
     3001 cccggacaag tgccgtctac ttccacaagc tgtcccaatg acacggacat ggagatggct
     3061 ggcctaaatc tggatgctga gcggaagcca gctgaaagcg agacaggcct ctcaccggag
     3121 gtctcaaatt gctacgagaa ggaggcgaga ggagcggagg gctcagatgt gcgtctggcc
     3181 cctgcagccc agcgaatgtc ctcccctcag ccagcagatg agagggcccg gcagtccagc
     3241 ccttttctcg atgactgcaa ggccaggggg tccccagaag atgggcctca tgaagtcagc
     3301 cccctggaag aaaaagccag ccccactact gaaagcgacc tccaaagcca ggcttgccaa
     3361 gaaaactcca ggtacacgga gacgagatct ctgaactcga gatcaccaga attcaccgaa
     3421 gcggagctga aagagcccct ttctttgcct tcctgggaac cagaggtgtt cagtgaactt
     3481 agcattcctc taggagtgga gttcgtggtt cccaggactg gcttttactg caagctgtgt
     3541 ggcctgttct acacaagcga ggaggcggcc aaagtgagcc actgccgcag cactgtacac
     3601 tacaggaact tacagaagta cctgtcccag ctggcagagg agggactgaa ggagacagag
     3661 ggggtagaca gcccaagccc cgagcgcagc gggattggtc cacacttgga aaggaagaag
     3721 ctatgatacc gaggctgcca ccgtctctgg aaggtggatg ggaagcctgc tgagctaagg
     3781 ccagcctggt ctcagggaca gaactgagac cagagaagaa ggagagccag gcaggacatg
     3841 ctgccgagat gagaaaaaca ccttgaagcc tctccaggag ctggctcacc cttccgggcc
     3901 cagccaccaa gggtgaccag cttcccatgg cctcctgatt cctttagtct gttttccctc
     3961 tctccctctc actatccctt ctgtgccaaa gtttatttcc ttttcataaa acccaacttc
     4021 tcagggattg tcgctgtgtt tcaagttttg attggatgtg gtaggtccgt caagtgaggc
     4081 tgggtcacac aagaaaaaag tttaatggaa ggtctgggct tagagttatt tcagtgaacc
     4141 tgaggtggcc ttggaacctg gcttctgtgc gtcccaaggg taggtaagct gtcaggttct
     4201 gcaaccaagg aatcagttgg cagaggtgga agtggtttca ctaaggtttc ctctagtcgg
     4261 atcctcgaaa aggcttcttt tttcttttca gtttctggct agtgctggaa atggaaccca
     4321 gaaggtcgta cattctaaac aggtgctgtc ccgatgagct gtctgcctag ccaacatgtc
     4381 ccagggacag ggctcacata gtccagggat tgcctttaat ttcttctgaa gccaaggtta
     4441 tcttgaactc ctcatcctcc tgcttctacc aactgagtgc tgtgatccca ggtattgtgc
     4501 cgggaggggg gggaacccag ggcttccagc acaagtggca agccatagcc ctatttgagg
     4561 aagtcattca tcctcagcta ctctagaaaa ccactgggct atgccttaat gtgcaattgc
     4621 accgtattat agcaacaatg cattattgta catcattagt atttaaattc acattcattt
     4681 tatggagtga agaagaaccc tgtattgaag aagctccaac agattcaatc caagcttctt
     4741 ggtttaagga ttattcagga tctgttctat tcaggacagt gaatatggta cattgactaa
     4801 gctcgaggtc agccatgtct tctctctaga ggatttactc cctcaaggag gcaatcaatg
     4861 taggcctaac gaacatcaca tgctgaccac tgccctctgc cctctggcct tcattcatcc
     4921 ttggtgcctc tgctttgggt tactcggtat tagaacgatt tgaaaatgct ctcccgtcag
     4981 aggagaaacc aagagacgga ggggttgctt atgccgactt ggaggttaaa acgttagaaa
     5041 gagcaggtcc ctgattccca gcagggtcag cgccccctcc catacgggct gaaggattgt
     5101 aggggaaggt cttgggacaa aggtaccgga aggcatgagt accactagag ccatagagcg
     5161 gatccccgaa tcagaaagcc tggcgctgtc ttcacgggta ggcatgcctc cttgaaggct
     5221 cccccaaacc ccccgtccat gtggatggtt tgcttgtgtg agtttcctgt ttatgttccc
     5281 aagcaaagga aggcagagca gacagggagc acgtctattt gctccccccc cccttatact
     5341 gacattctac attctccacc aacagaaggg ctgtggagaa atgatttagt tcagtgctaa
     5401 cattttatca tcggggaaac tgaggcacag aaaggagaca ggcgtagaac ctaaaataac
     5461 catgtgtcca cttggaggcc tgtggctcct gggcaggagt gaaagaactt ctgggatctg
     5521 tgaaagagga gttagacaga gagaggccag tctggaaagg agtgatagga agttggggct
     5581 tcgggaaggt gatatccatc ccctggtgga tcccagagga ggtaacctag cgtcatggtc
     5641 atgagcaaag tctctgctat ttctcagaaa acctttgacc tctgggaaca gctgctgccc
     5701 acatccctac acccatcagc acccccatca gaggctggac atgatttctc ttccagcaga
     5761 gtgaggcaga cctcccaaca gcactggctc ccctgctagt ggcctttcta agggaagcca
     5821 catggcccag ctctcagcag cgggatggct cccttggcta tacattgacc atcatataaa
     5881 tatcagcaaa actgaagggt taaagaaaca gcagtctcta tgtttaaagt catggatggt
     5941 cctatacatg tgtgtgtata tatacgtata tatttttata taattccatt ggcatggttc
     6001 ttgcattttt taaaaattcc tgtgtgtgtt ccatgcatca cagtattaaa gacaaccagg
     6061 aagatattta tttctttttt tattttattt tattttattt tattttattt tttttttttt
     6121 ttggagctgg ggaccgaacc cagggccttg cgcttcctag gtaagcgctc taccactgag
     6181 ctaaatcccc agcccctctt tttttaaaac attaattcag tgtctcgtca atcattacaa
     6241 aacgtctctc cccaaggttg ctcataaaca gttgctacct tgtataaaaa attcatttgt
     6301 gccctgggtt aatgtgtcag caagccagtg tccttgagta ctcactgttg gtacctgatg
     6361 gtcctccagg tggcacaccc agaggctgta gtgaacctgt tgggtgagca gcagccatta
     6421 gcgttcaggt ttcccattct tggacagtcc gaggcggtga tctgtaaggt tatgcttgaa
     6481 ctggaccaga gttcctttgt ttctgtgaga ttttgaaaaa cagaactatc agttaagttt
     6541 gaacttgtaa agtattagag tattttgagt gtcttatata aattgtcacc actttttctg
     6601 atctatataa ttgacctaaa gtgtttgttt ttacaaaagg aaaaaaatgg tttttaataa
     6661 agagaatttg aaagcttgtg ag
//
