LOCUS       NM_001013058            1560 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus RNA binding motif protein 17 (Rbm17), mRNA.
ACCESSION   NM_001013058 XM_214504
VERSION     NM_001013058.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1560)
  AUTHORS   Lim J, Crespo-Barreto J, Jafar-Nejad P, Bowman AB, Richman R, Hill
            DE, Orr HT and Zoghbi HY.
  TITLE     Opposing effects of polyglutamine expansion on native protein
            complexes contribute to SCA1
  JOURNAL   Nature 452 (7188), 713-718 (2008)
   PUBMED   18337722
REFERENCE   2  (bases 1 to 1560)
  AUTHORS   Corsini L, Bonnal S, Basquin J, Hothorn M, Scheffzek K, Valcarcel J
            and Sattler M.
  TITLE     U2AF-homology motif interactions are required for alternative
            splicing regulation by SPF45
  JOURNAL   Nat Struct Mol Biol 14 (7), 620-629 (2007)
   PUBMED   17589525
  REMARK    Erratum:[Nat Struct Mol Biol. 2007 Aug;14(8):785. Bonna, Sophie
            [corrected to Bonnal, Sophie]]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079248.1.
            
            On Apr 20, 2005 this sequence version replaced XM_214504.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079248.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1560
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q12.2"
     gene            1..1560
                     /gene="Rbm17"
                     /note="RNA binding motif protein 17"
                     /db_xref="GeneID:291295"
                     /db_xref="RGD:1311208"
     exon            1..115
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            116..253
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..1348
                     /gene="Rbm17"
                     /codon_start=1
                     /product="splicing factor 45"
                     /protein_id="NP_001013076.1"
                     /db_xref="GeneID:291295"
                     /db_xref="RGD:1311208"
                     /translation="MSLYDDLGVETSDSKTEGWSKNFKLLQSQLQVKKAALTQAKSQR
                     TKQSTVLAPVIDLKRGGSSDDRQIVDTPPHVAAGLKDPVPSGFSAGEVLIPLADEYDP
                     MFPNDYEKVVKRQREERQRQRELERQKEIEEREKRRKDRHEASGFSRRPDPDSDEDED
                     YERERRKRSMGGAAIAPPTSLVEKDKELPRDFPYEEDSRPRSQSSKAAIPPPVYEEPD
                     RPRSPTGPSNSFLANMGGTVAHKIMQKYGFREGQGLGKHEQGLSTALSVEKTSKRGGK
                     IIVGDATEKGESQDASKKSDSNPLTEILKCPTKVVLLRNMVGAGEVDEDLEVETKEEC
                     EKYGKVGKCVIFEIPGAPDDEAVRIFLEFERVESAIKAVVDLNGRYFGGRVVKACFYN
                     LDKFRVLDLAEQV"
     exon            254..370
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            371..537
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            538..635
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            636..692
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            693..834
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            835..998
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            999..1072
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1171
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1244
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..1528
                     /gene="Rbm17"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtggaggct cggtgctgcg gcgggctccg gcggtgggcg ggcttccgcg cagggcggcc
       61 gggctcggcg ctgccgccgc cgtggcccat gggcacagtc gtctcggaag gccggtatta
      121 aaccaaaaag atgtccctat atgatgacct gggagtggag accagtgact caaaaactga
      181 aggctggtcc aaaaacttca agcttctgca gtcccagctc caggtgaaga aggcagctct
      241 cactcaagcc aagagccaaa ggacaaagca aagtacagtc ctcgctccag tcatcgacct
      301 gaagcgagga ggctcctcag atgaccgaca gatcgtagac acgccacctc atgtggcagc
      361 tgggctgaag gaccctgtgc ccagtgggtt ctctgcaggg gaagtcctga tccccttggc
      421 tgatgaatat gacccaatgt ttcctaacga ctatgagaaa gtggtgaagc gccagagaga
      481 agagcggcag aggcagcggg agctggaaag acagaaggaa atagaggaaa gagaaaagag
      541 gcgtaaagac agacatgaag ccagtgggtt ttcaagacgc ccagacccgg actcggatga
      601 ggatgaagat tatgagcgag agcggaggaa aagaagtatg gggggagctg ccatcgcccc
      661 accgacctct ctggtagaga aagacaaaga gttaccccga gattttccct atgaagagga
      721 ctcaagacct cgatcacagt cttccaaagc tgctattcct cccccagtgt atgaggagcc
      781 ggacagacca aggtctccaa ccggccccag caactccttc ctcgctaaca tgggtggcac
      841 cgtggctcat aagatcatgc agaagtatgg cttccgggaa ggtcaggggc tggggaaaca
      901 tgagcaaggg ctaagcactg cattgtccgt ggagaagacc agcaagcgtg gcggcaagat
      961 cattgttggt gacgccacag agaagggcga gtctcaggat gcatccaaga agtcggattc
     1021 aaatccatta actgaaattc ttaagtgccc tactaaagtg gtcttgctga ggaacatggt
     1081 cggtgcagga gaggtcgatg aagacttgga agttgaaacc aaggaagaat gtgaaaaata
     1141 tggcaaagtt gggaaatgtg tgatatttga gattcctggt gcccctgatg atgaagcagt
     1201 acggatattt ctagaatttg agagagtcga atcggcaatt aaagctgttg tcgatctgaa
     1261 tgggaggtat tttggtggac gggtggttaa agcctgtttc tacaatttgg ataaattcag
     1321 ggtcttggat ctagcagagc aagtgtgatt gtaacttaaa gtcacctcct tgatccttac
     1381 acgagctgca gactgagcaa tggcacaggc gtcagcctcc atggctgctg gacactgaaa
     1441 ctcttggatg gacttctaag atatatgttg atggatccct tttttatttt gtgttttttt
     1501 aatatagtat aaaaatcctt taaaaatcaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
