LOCUS       NM_133388               3144 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus RNA binding motif protein 14 (Rbm14), mRNA.
ACCESSION   NM_133388 XM_002728823
VERSION     NM_133388.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3144)
  AUTHORS   Morchikh,M., Cribier,A., Raffel,R., Amraoui,S., Cau,J., Severac,D.,
            Dubois,E., Schwartz,O., Bennasser,Y. and Benkirane,M.
  TITLE     HEXIM1 and NEAT1 Long Non-coding RNA Form a Multi-subunit Complex
            that Regulates DNA-Mediated Innate Immune Response
  JOURNAL   Mol Cell 67 (3), 387-399 (2017)
   PUBMED   28712728
REFERENCE   2  (bases 1 to 3144)
  AUTHORS   Simpson,M.T., Venkatesh,I., Callif,B.L., Thiel,L.K., Coley,D.M.,
            Winsor,K.N., Wang,Z., Kramer,A.A., Lerch,J.K. and Blackmore,M.G.
  TITLE     The tumor suppressor HHEX inhibits axon growth when prematurely
            expressed in developing central nervous system neurons
  JOURNAL   Mol Cell Neurosci 68, 272-283 (2015)
   PUBMED   26306672
  REMARK    GeneRIF: This study idnetifed that the RBM14 as inhibitors of
            neurite outgrowth.
REFERENCE   3  (bases 1 to 3144)
  AUTHORS   Shiratsuchi,G., Takaoka,K., Ashikawa,T., Hamada,H. and Kitagawa,D.
  TITLE     RBM14 prevents assembly of centriolar protein complexes and
            maintains mitotic spindle integrity
  JOURNAL   EMBO J 34 (1), 97-114 (2015)
   PUBMED   25385835
REFERENCE   4  (bases 1 to 3144)
  AUTHORS   Redshaw,N., Camps,C., Sharma,V., Motallebipour,M., Guzman-Ayala,M.,
            Oikonomopoulos,S., Thymiakou,E., Ragoussis,J. and Episkopou,V.
  TITLE     TGF-beta/Smad2/3 signaling directly regulates several miRNAs in
            mouse ES cells and early embryos
  JOURNAL   PLoS One 8 (1), e55186 (2013)
   PUBMED   23390484
REFERENCE   5  (bases 1 to 3144)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   6  (bases 1 to 3144)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   7  (bases 1 to 3144)
  AUTHORS   Li,X., Hoeppner,L.H., Jensen,E.D., Gopalakrishnan,R. and
            Westendorf,J.J.
  TITLE     Co-activator activator (CoAA) prevents the transcriptional activity
            of Runt domain transcription factors
  JOURNAL   J Cell Biochem 108 (2), 378-387 (2009)
   PUBMED   19585539
  REMARK    GeneRIF: CoAA binds Runx2 and prevents Runx2 binding to DNA
REFERENCE   8  (bases 1 to 3144)
  AUTHORS   Iwasaki,T., Koibuchi,N. and Chin,W.W.
  TITLE     Synovial sarcoma translocation (SYT) encodes a nuclear receptor
            coactivator
  JOURNAL   Endocrinology 146 (9), 3892-3899 (2005)
   PUBMED   15919756
REFERENCE   9  (bases 1 to 3144)
  AUTHORS   Iwasaki,T., Chin,W.W. and Ko,L.
  TITLE     Identification and characterization of RRM-containing coactivator
            activator (CoAA) as TRBP-interacting protein, and its splice
            variant as a coactivator modulator (CoAM)
  JOURNAL   J Biol Chem 276 (36), 33375-33383 (2001)
   PUBMED   11443112
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Sep 16, 2012 this sequence version replaced XM_002728823.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643290.4703.1,
                                           SRR26643298.6439.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMN12840108 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-443               JAXUCZ010000001.1  211534623-211535065 c
            444-1908            JAXUCZ010000001.1  211525975-211527439 c
            1909-3144           JAXUCZ010000001.1  211523972-211525207 c
FEATURES             Location/Qualifiers
     source          1..3144
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..3144
                     /gene="Rbm14"
                     /gene_synonym="CoAA"
                     /note="RNA binding motif protein 14"
                     /db_xref="GeneID:170900"
                     /db_xref="RGD:620542"
     exon            1..443
                     /gene="Rbm14"
                     /gene_synonym="CoAA"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..2116
                     /gene="Rbm14"
                     /gene_synonym="CoAA"
                     /note="coactivator activator"
                     /codon_start=1
                     /product="RNA-binding protein 14"
                     /protein_id="NP_596879.1"
                     /db_xref="GeneID:170900"
                     /db_xref="RGD:620542"
                     /translation="MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRE
                     NAGAVRAIEALHGHELRPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERR
                     GRVIECDVVKDYAFVHMEKEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPALAIQ
                     SGDKTKKPGAGDTAFPGTGGFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLR
                     RSPPRASYVAPLTAQPATYRAQPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQ
                     PSVSLGAPYRGQLASPSSQSAAASSLGPYGGVQPSASALSTYGGQAAAASSLNSYGAQ
                     GSSLASYGNQPSSYGAQAASSYGVRAAASSYNTQGAASSLGSYGAQAASYGAQSAASS
                     LAYGAQAASYNAQPSASYSAQSAPYAAQQAASYSSQPAAYVAQPAAAAAYASQPAAYA
                     AQATTPMAGSYGAQPVVQTQLNSYGAQASMGLSGSYGAQSAAAATGSYGAAAAYGAQP
                     SATLAAPYRTQSSASLAASYAAQQHPQAAASYRGQPGSAYDGTGQPSAAYLSMSQGAV
                     ANANSTPPPYERTRLSPPRASYDDPYKKAVAMSKRYGSDRRLAELSDYRRLSESQLSF
                     RRSPTKSSLDYRRLPDAHSDYARYSGSYNDYLRAAQMHSGYQRRM"
     exon            444..1908
                     /gene="Rbm14"
                     /gene_synonym="CoAA"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..3144
                     /gene="Rbm14"
                     /gene_synonym="CoAA"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctcgctcgc cagccattcc tgtagaggac tgcgggtcgt tcggacgttt tgcctgtcgc
       61 tgtaggagag gtccagtctc tccgagaagg cggttgcggc ggcaaaatga agatctttgt
      121 aggcaatgtc gacggggcgg atacgacgcc ggaggagctg gcagccctct tcgcgcccta
      181 tggcacggtc atgagctgcg ccgtcatgaa acagtttgcc ttcgtgcaca tgcgcgagaa
      241 cgctggcgcg gtgcgcgcca tcgaggccct gcatggccac gagctgcgtc caggtcgcgc
      301 gctcgtggtg gagatgtcgc gcccgaggcc cctgaacact tggaagattt tcgtgggcaa
      361 tgtatcggct gcatgcacaa gccaggaatt gcgcagcctg ttcgagcgcc gtggacgcgt
      421 catcgagtgt gacgtggtaa aagactacgc gtttgttcac atggagaagg aagcagatgc
      481 caaagccgcc atcgcgcagc tcaacggcaa agaagtgaag ggcaagcgca tcaacgtgga
      541 actctcaacc aaggggcaga agaaggggcc tgccctggct atccagtctg gggacaagac
      601 caagaaacca ggggctgggg atacagcatt ccctggaact ggtggcttct ctgccacctt
      661 cgactaccag caggcttttg gcaacagcac tggtggcttt gatgggcaag cccgtcagcc
      721 cacaccacca ttctttggtc gcgaccgcag ccccctgcgc cgttcacctc ctcgagcctc
      781 ttatgtggct cctctgacgg cccagccagc cacctaccgg gcccaaccct ctgtgtctct
      841 gggagctgca tatagggccc agccttcggc ctctttgggt gtcggctatc ggactcagcc
      901 catgacagcc caggcagctt cgtaccgtgc tcaaccctct gtctcccttg gggccccata
      961 caggggtcaa ctggctagcc ctagttccca gtctgctgca gcttcctcac ttggcccata
     1021 tggtggagtc cagccctcag cctcagccct ttccacctat gggggtcagg cagctgcagc
     1081 ttcttcgctt aattcctatg gggctcaggg ctcctccctt gcttcctatg gtaaccagcc
     1141 atcctcttat ggcgcccagg ctgcctcttc atatggggtt cgtgcggctg cttcttccta
     1201 taacacacag ggagcagctt cttccctagg ttcctatggg gctcaagcag cctcctatgg
     1261 tgcccagtct gcagcctcct cactagctta tggagcccag gcagcctctt acaatgccca
     1321 gccctcagcc tcttacagtg cccagtctgc cccatatgct gcacaacagg ctgcttctta
     1381 ttcttcccag cctgctgctt atgtggcaca gccagccgca gctgctgcct atgctagcca
     1441 gccagctgcc tatgctgcac aggccactac cccaatggcc ggttcctatg gggctcaacc
     1501 agttgttcag acccagctga atagttatgg agctcaagca tctatgggcc tgtcaggctc
     1561 atatggagct cagtctgctg ctgcggccac tggctcctat ggtgcagcag ctgcctatgg
     1621 ggcgcagcct tctgccacct tggcagctcc ttaccgcact cagtcatcag cctcattggc
     1681 tgcttcctat gctgcccagc agcatcccca ggctgctgcc tcctaccgtg gccagccggg
     1741 cagtgcctac gatgggacag gccagccgtc agcagcctac ctgtctatgt cccagggggc
     1801 cgttgccaac gccaacagca ccccaccgcc ctatgagcgt acccgcctct ccccaccccg
     1861 ggccagctac gacgatccct acaaaaaggc tgtcgccatg tcgaaaaggt atggttccga
     1921 ccggcgttta gccgagctct ctgattaccg ccgtttatca gagtcgcagc tttcgttccg
     1981 ccgctcgccg acaaagtcct cgctggatta ccgtcgcctg cccgatgccc attccgatta
     2041 cgcacgctat tcgggctcct ataatgatta cctgcgggca gctcagatgc actctggcta
     2101 ccagcgccgc atgtagggct atcctgggga tggggcacca caggagggga gagagaggga
     2161 gagatagggt agggtgcaga cccatgttat caccaccctc tctcatacct ctccctatgg
     2221 tggctattca ttccctccct ctaccatgtg ggccttcccc aggagaggac ccttttgtgt
     2281 ttggcagtaa cctgctttgt ttctttgcct cagcagcaca tcttgctact ggctttagat
     2341 ctgcggtttt ccctctaccc agccatctcc ccaaaatggg aatttctttt atattttttt
     2401 tttcctggct cccttttatt tttgtgcgcg atacttaagg ttgtttggag gtgacacaac
     2461 ctacagctga ggtcaggcgg cgcgttattc tttttagatg tgagggaggc caggaaagag
     2521 ttactttaac catttcctat gtgctgtgcc agcagtccag gggaccctga ctgtccgtgt
     2581 agcctgttga gactgagatc ctgttgggac agtcagttgg tatgtgtcca aatccctgct
     2641 taccactgat gttttagctg acggtgactg gcatggtccc aattccctat ctccccaagt
     2701 aggtggtatt agaaatctta attttccccc cctcttttgt atggactaca aataaaactt
     2761 ggggcgattc gtggtttgga aacctggttg tcattgtctt gattgcactg tcaggtgagc
     2821 cagtttgaca tccaggaaga cgtgacagct agaagagagg cagcctgaag acccagagtg
     2881 ggtgtggaaa ggcttggatg tgggattgga gtggttccct ggtaaccaat ggagttaagc
     2941 tcattatcgt cttaaatagc acgccatctt tgggactgca gagttcagac caagtggttg
     3001 gactttctca gcaatcaatt ttagttgatc acatcaaaat ttagtaaaca atgcccgttt
     3061 cctctgctta tgtttgacca ctgtccctga ttttttccca attcaagaaa aacaaaaata
     3121 aaacaaaact acagttcagc agga
//
