LOCUS       NM_152861               3106 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus RNA binding motif protein 10 (Rbm10), transcript
            variant 1, mRNA.
ACCESSION   NM_152861
VERSION     NM_152861.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3106)
  AUTHORS   Shang,Y., Li,X., Liu,W., Shi,X., Yuan,S., Huo,R., Fang,G., Han,X.,
            Zhang,J., Wang,K., Dou,Z., Zhang,Y., Zang,A. and Zhang,L.
  TITLE     Comprehensive genomic profile of Chinese lung cancer patients and
            mutation characteristics of individuals resistant to
            icotinib/gefitinib
  JOURNAL   Sci Rep 10 (1), 20243 (2020)
   PUBMED   33219256
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3106)
  AUTHORS   Xu,T., Zhang,Y., Zhang,J., Qi,C., Liu,D., Wang,Z., Li,Y., Ji,C.,
            Li,J., Lin,X., Hou,T., Liu,H., Zhang,L., Han-Zhang,H., Shen,L. and
            Wang,X.
  TITLE     Germline Profiling and Molecular Characterization of Early Onset
            Metastatic Colorectal Cancer
  JOURNAL   Front Oncol 10, 568911 (2020)
   PUBMED   33194656
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3106)
  AUTHORS   Zhao,Z., Li,J. and Shen,F.
  TITLE     Protective effect of the RNA-binding protein RBM10 in
            hepatocellular carcinoma
  JOURNAL   Eur Rev Med Pharmacol Sci 24 (11), 6005-6013 (2020)
   PUBMED   32572914
REFERENCE   4  (bases 1 to 3106)
  AUTHORS   Jin,X., Di,X., Wang,R., Ma,H., Tian,C., Zhao,M., Cong,S., Liu,J.,
            Li,R. and Wang,K.
  TITLE     RBM10 inhibits cell proliferation of lung adenocarcinoma via
            RAP1/AKT/CREB signalling pathway
  JOURNAL   J Cell Mol Med 23 (6), 3897-3904 (2019)
   PUBMED   30955253
REFERENCE   5  (bases 1 to 3106)
  AUTHORS   Yin,L.L., Wen,X.M., Li,M., Xu,Y.M., Zhao,X.F., Li,J. and Wang,X.W.
  TITLE     A gene mutation in RNA-binding protein 10 is associated with lung
            adenocarcinoma progression and poor prognosis
  JOURNAL   Oncol Lett 16 (5), 6283-6292 (2018)
   PUBMED   30405763
REFERENCE   6  (bases 1 to 3106)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   7  (bases 1 to 3106)
  AUTHORS   Hegele,A., Kamburov,A., Grossmann,A., Sourlis,C., Wowro,S.,
            Weimann,M., Will,C.L., Pena,V., Luhrmann,R. and Stelzl,U.
  TITLE     Dynamic protein-protein interaction wiring of the human spliceosome
  JOURNAL   Mol Cell 45 (4), 567-580 (2012)
   PUBMED   22365833
REFERENCE   8  (bases 1 to 3106)
  AUTHORS   Mueller,C.F., Berger,A., Zimmer,S., Tiyerili,V. and Nickenig,G.
  TITLE     The heterogenous nuclear riboprotein S1-1 regulates AT1 receptor
            gene expression via transcriptional and posttranscriptional
            mechanisms
  JOURNAL   Arch Biochem Biophys 488 (1), 76-82 (2009)
   PUBMED   19508861
  REMARK    GeneRIF: Overexpression of S1-1 sense resulted in VSMC in
            significant stabilization of AT1 receptor mRNA.
REFERENCE   9  (bases 1 to 3106)
  AUTHORS   Zhu,P., Zhou,W., Wang,J., Puc,J., Ohgi,K.A., Erdjument-Bromage,H.,
            Tempst,P., Glass,C.K. and Rosenfeld,M.G.
  TITLE     A histone H2A deubiquitinase complex coordinating histone
            acetylation and H1 dissociation in transcriptional regulation
  JOURNAL   Mol Cell 27 (4), 609-621 (2007)
   PUBMED   17707232
REFERENCE   10 (bases 1 to 3106)
  AUTHORS   Inoue,A., Takahashi,K.P., Kimura,M., Watanabe,T. and Morisawa,S.
  TITLE     Molecular cloning of a RNA binding protein, S1-1
  JOURNAL   Nucleic Acids Res 24 (15), 2990-2997 (1996)
   PUBMED   8760884
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000021.1.
            
            On Dec 2, 2020 this sequence version replaced NM_152861.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D83948.1, SRR26643292.64831.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-203               JAXUCZ010000021.1  4125822-4126024     c
            204-344             JAXUCZ010000021.1  4123722-4123862     c
            345-528             JAXUCZ010000021.1  4108914-4109097     c
            529-598             JAXUCZ010000021.1  4105233-4105302     c
            599-672             JAXUCZ010000021.1  4103436-4103509     c
            673-759             JAXUCZ010000021.1  4101797-4101883     c
            760-820             JAXUCZ010000021.1  4099779-4099839     c
            821-997             JAXUCZ010000021.1  4099487-4099663     c
            998-1158            JAXUCZ010000021.1  4098941-4099101     c
            1159-1256           JAXUCZ010000021.1  4098673-4098770     c
            1257-1344           JAXUCZ010000021.1  4098423-4098510     c
            1345-1528           JAXUCZ010000021.1  4097233-4097416     c
            1529-1668           JAXUCZ010000021.1  4096996-4097135     c
            1669-1786           JAXUCZ010000021.1  4096763-4096880     c
            1787-1878           JAXUCZ010000021.1  4096588-4096679     c
            1879-2043           JAXUCZ010000021.1  4096323-4096487     c
            2044-2193           JAXUCZ010000021.1  4095509-4095658     c
            2194-2259           JAXUCZ010000021.1  4095341-4095406     c
            2260-2448           JAXUCZ010000021.1  4095075-4095263     c
            2449-2523           JAXUCZ010000021.1  4094915-4094989     c
            2524-2630           JAXUCZ010000021.1  4094550-4094656     c
            2631-2760           JAXUCZ010000021.1  4094343-4094472     c
            2761-3106           JAXUCZ010000021.1  4093914-4094259     c
FEATURES             Location/Qualifiers
     source          1..3106
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq11"
     gene            1..3106
                     /gene="Rbm10"
                     /note="RNA binding motif protein 10"
                     /db_xref="GeneID:64510"
                     /db_xref="RGD:631366"
     exon            1..203
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            204..344
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     CDS             328..2886
                     /gene="Rbm10"
                     /function="RNA metabolism"
                     /note="isoform 1 is encoded by transcript variant 1;
                     RNA-binding protein 10; RNA-binding protein S1-1; S1-1
                     protein from liver"
                     /codon_start=1
                     /product="RNA-binding protein 10 isoform 1"
                     /protein_id="NP_690600.1"
                     /db_xref="GeneID:64510"
                     /db_xref="RGD:631366"
                     /translation="MEYERRGGRGDRTGRYGATDRSQDDGGENRSRDHDYRDMDYRSY
                     PREYGSQEGKHEYDDSSEEQSAEIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFS
                     HLQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCG
                     VPKSEAEQKLPLGTRLDQQALPLGGRELSQGLLPLPQPYQAQGVLTSQALSQGSEPSS
                     ENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTI
                     VEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRINAASVASTAIAAAQ
                     WAISQASQGGESTWAAPEEPPVDYSYYQQDEGYGSSQGTDSLYAHGYLKNTKGPGMTG
                     TKGDTSGAGPETSLEGGTDSVSLQAFSRAQPGAAPGLYQQSAEGSSGQGTATNSQSYT
                     IMSPAVLKSELQSPTHPSSALPPATSPTAPESYSQYPVPDVSTYQYDETSGYYYDPQT
                     GLYYDPNSQYYYNAQSQQYLYWDGERRTYIPALEQSADGHKDTGASSKEGKEKKEKHK
                     TKTAQQIAKDMERWARSLNKQKENFKNSFQPISALRDDERRESATADAGYAILEKKGA
                     LAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLA
                     CLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRA
                     AERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSG
                     LGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ"
     exon            345..528
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            529..598
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            599..672
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            673..759
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            760..820
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            821..997
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            998..1158
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1256
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            1257..1344
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1528
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            1529..1668
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1786
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            1787..1878
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2043
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            2044..2193
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            2194..2259
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            2260..2448
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            2449..2523
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            2524..2630
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            2631..2760
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
     exon            2761..3106
                     /gene="Rbm10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggctgggag gaggcggcac tgagtttcct tgggagggca acgcgttggg cgcgtctccc
       61 ttccccctgt cctccctttt gcctccagtc ttggacttgg tagttgcatg cattggctcc
      121 cgtcgaacta acagttctga aggaggtagt ggcgggcgga ggtgatgcct gggagccctc
      181 ccttgacagc ccgggccgag aagagtctct gcaggaggta tcacccagac tgacagatca
      241 tgctgacagc agcaggggag gctgagaagt gaaaggagcc agctactgag gaggggctcc
      301 agtagctcct aaagatccta tcaggacatg gagtatgaaa gacgaggtgg tcgtggtgac
      361 agaactggcc ggtatggagc tactgaccgc tcacaggacg atggtggaga gaaccgcagc
      421 cgagaccatg attatagaga catggactat cgttcatacc cacgagagta tggcagtcag
      481 gaaggcaagc atgagtatga cgactcatct gaagagcaaa gtgcagagat ccgtggccag
      541 ctgcagtccc atggtgtcca agcacgagag gtccggctga tgcggaacaa atcctcaggt
      601 cagagccggg gcttcgcctt cgtcgagttt agtcacttgc aggacgctac acgatggatg
      661 gaagccaatc agcattccct caacatcctg ggccagaagg tatccatgca ttacagcgac
      721 cccaagccca agatcaatga ggactggctg tgtaataagt gtggtgtcca gaacttcaag
      781 cgccgagaga agtgcttcaa atgcggtgtg cccaaatcag aagcagagca gaagctaccc
      841 cttggcactc gactggatca gcaggcacta ccgttgggtg ggcgggagct aagccagggc
      901 ctactcccac tgccgcagcc ctaccaggcc cagggagtgc tgacctcgca agccttgtca
      961 cagggctcag agccaagctc cgagaatgcc aatgacacca ttattttacg caacctgaac
     1021 ccacacagca ctatggattc catcctcggg gccctagcac cctatgcggt gctgtcctct
     1081 tccaatgttc gtgttatcaa ggacaagcag acccagctga accgaggctt cgccttcatc
     1141 cagctctcca ccatcgtgga agcagcccag ctgctacaga tccttcaggc cctacaccct
     1201 ccgctcacca tcgatggcaa gaccatcaac gtggagtttg ccaagggctc taagagggat
     1261 atggcctcca atgaaggcag tcgcatcaat gctgcctctg tggccagcac tgccattgct
     1321 gctgcccagt gggcaatctc acaggcctcc cagggtgggg agagtacctg ggctgccccc
     1381 gaggagccac cagttgacta cagctactac caacaggatg agggctatgg cagcagccag
     1441 ggaacagatt ccctctatgc ccatggctac cttaagaata ccaagggccc tggcatgact
     1501 gggaccaaag gggacacatc tggagcaggt cctgagacct cccttgaggg tgggacagac
     1561 tctgtgtcac tgcaggcttt ctctcgagcc cagcctggtg ctgcccctgg actctatcag
     1621 caatcagctg aggggagcag tggccagggc actgctacca acagccagtc atataccatc
     1681 atgtcacctg ctgtgctcaa gtctgagctc cagagcccta ctcatcccag ctctgcctta
     1741 ccaccggcca ccagtcccac tgccccagag tcctacagcc agtaccctgt tcctgatgtc
     1801 tctacttacc aatatgatga gacatctggc tactactatg acccccagac tggtctatac
     1861 tatgatccca actcccagta ttactacaat gctcagagtc agcagtacct atactgggat
     1921 ggggagcggc ggacctacat acctgccttg gagcagtctg ctgatggaca taaggacaca
     1981 ggggcatcat caaaggaggg aaaagagaaa aaagagaagc ataagacgaa gacggcccaa
     2041 cagattgcca aggacatgga gcggtgggcc cgcagtctca acaagcaaaa agaaaacttc
     2101 aaaaacagct tccagcctat tagtgctcta cgagatgatg aaaggcggga atcagccact
     2161 gcagatgcag gctatgccat ccttgagaag aagggagcac tagctgaaag acagcacacc
     2221 agcatggatc tcccaaagtt ggccagtgat gaccgcccta gcccacctcg agggctggtg
     2281 gcagcctata gtggagagag tgacagtgag gaggagcagg agcgaggggg tcctgagcgg
     2341 gaagaaaagc tcacagactg gcagaagcta gcctgtctgc tctgccgccg ccagtttccc
     2401 agcaaggagg cgctcatccg gcaccagcag ctctctggac tccacaagca aaaccttgag
     2461 attcatcgac gggcccactt gtcagaaaat gaattggaag cactagaaaa gaatgacatg
     2521 gagcaaatga agtatcgaga ccgtgcagct gaacgcagag agaagtatgg tatccctgag
     2581 ccaccagagc ccaaacggag gaagtacggt ggcatatcta cagcctctgt ggactttgaa
     2641 cagcccactc gggatggatt aggcagtgac aacattggta gtcgaatgct ccaggccatg
     2701 ggctggaaag aaggcagtgg tctgggccgc aagaagcagg gcattgtgac acccattgaa
     2761 gcccaaacac gtgttcgagg ttctggcctg ggtgcccggg gaagttccta tggggtcacc
     2821 tcaacagaat cctacaagga gacactgcac aagacaatgg tgacccgctt caatgaagcc
     2881 cagtgaacaa ctttgaaagc agtttctaca gacaaggggt attcatccag ggacagagaa
     2941 gatgaggtct ggaatggtct gaggaaggct cttctatcta ccagcctgct gcccaaccag
     3001 agaggccctc accaaattag acttggagtt gctgactttt gctgggaaat tgggctcaaa
     3061 tcatgtttct tttgtaataa aatctaaaaa gcctgcatct tccatt
//
