LOCUS       XM_017590222            8023 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus RB binding protein 6, ubiquitin ligase
            (Rbbp6), transcript variant X1, mRNA.
ACCESSION   XM_017590222
VERSION     XM_017590222.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051336.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 11, 2024 this sequence was replaced by
            NM_001427187.1.
            
            On Jan 21, 2021 this sequence version replaced XM_017590222.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8023
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8023
                     /gene="Rbbp6"
                     /note="RB binding protein 6, ubiquitin ligase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 46 ESTs, 2 long SRA reads, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 39 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:308968"
                     /db_xref="RGD:1311964"
     CDS             413..5896
                     /gene="Rbbp6"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RBBP6 isoform X1"
                     /protein_id="XP_017445711.1"
                     /db_xref="GeneID:308968"
                     /db_xref="RGD:1311964"
                     /translation="MSCVHYKFSSKLNYDTVTFDGLHISLCDLKKQIMGREKLKAADS
                     DLQITNAQTKEEYTDDNALIPKNSSVIVRRIPIGGVKSTSKTYVISRTEPVMGTTKAI
                     DDSSASISLAQLTKTANLAEANASEEDKIKAMMSQSGHEYDPINYMKKTLVGPPPPSY
                     TCFRCGKPGHYIKNCPTNGDKNFESGPRIKKSTGIPRSFMMEVKDPNMKGAMLTNTGK
                     YAIPTIDAGRLLFHKLGTMGHKQIDTYLWNRGDVYGAAATQITHLREAYAIGKKEKPP
                     FLPEEPSSSSEEDDPIPDELLCLICKDIMTDAVVIPCCGNSYCDECIRTALLESDEHT
                     CPTCHQNDVSPDALIANKFLRQAVNNFKNETGYTKRLRKQLPPPPPPISAPRPLIQRN
                     LQPLMRSPISRQQDPLMIPVTSSSAHSTPSISSLTSNPSSLAPSVPGNPSSAPAPVPD
                     ITATVSISVHSEKSDGPFRDSDNKLLPAAALASEHSKGASSIAITALMEEKGYQVPVL
                     GTPSLLGQSLLHGQLIPTTGPVRINAARPGGGRPGWEHSNKLGYLVSPPQQIRRGERS
                     CYRSINRGRHHSERSQRTQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSP
                     QFPPGQPPPAGYSVPPPGFPPAPANISTPWVSSGVQTAHSNTIPTTQAPPLSREEFYR
                     EQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYT
                     YSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSR
                     SPPYRRYHSRSRSPQAFRGQSPTKRNVPQGETEREYFNRYREVPPPYDIKAYYGRSVD
                     FRDPFEKERYREWERKYREWYEKYYKGYAVGAQPRPSANREDFSPERLLPLNIRNSPF
                     TRGRREDYVAGQSHRNRNLGGNYPEKISTRDSHNPKDNPKSKEKESENVPGDGKGNKH
                     KKHRKRRKGEESESFLNPELLETSRKSRESSGIDETKTDALFVLPSRDDATPVRDEPM
                     DAESITFKSVSEKDKREKDKPKVKSDKTKRKSDGSATAKKENVLKPSKGPQDKVDGDR
                     EKSPRSEPPLKKAKEEATKVDSVKPSSSQKDEKVTGTPRKAHSKSAKEHQEAKPVKEE
                     KAKKDCSKDIKSEKPASKDEKAKKPEKNKLLESKGEKRKRKTEEKSVDFESSSMKISK
                     VEGTEIVKPSPKRKMEGDVEKLERTPEKDKSASSTTPAKKIKLNRETGKKIGNAENPS
                     TTKEPSEKLESTSNKIKQEKVKGKARRKVAGTEGPSSTLVDYTSTSSTGGSPVRKSEE
                     KTDTKRTVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDDVRTTQPIQS
                     VGKPSSIIKNVTTKPSATVKCTEKENEQSEKIQKLTKEVSHEVIQHELRSSKGSVSSE
                     KGRAKDRDHSASEKDNPDKRKTSIQPDKESTVDRLSEQGHFKNLSQSSKETRTSEKHE
                     SVRGSSNKDFTPGRDKKTDYDSRDYSSSKRRDERSELTRRKDSPPRSKDSLSGQKSKL
                     REEKDLPKKGTELKKSNSSPPRDKKPHDHKASYETKRSCEETKSVDKNAGKEREKHAA
                     EASRNGKESSGSKLPSIPNPPDPPMEKELAAGQIEKSTIKPKPQLSHSSRLSSDLTRE
                     TDEAAFEPDYNESDSESNVSVKEEEAVASVSKDLKEKATEKATESLNVATASQPGADR
                     SQSQSSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKDKKKHKKHKKHKKH
                     KKHAGVDGDVEKSQKHKHKKKKAKKNKDKEKEKDDQKVKSVTV"
ORIGIN      
        1 actagccggg aggtgcggcc gctatggacc cctgaccccg cggggtcatt cggactctaa
       61 cgtgtggact gaccgctact gactgcaccg cctgccccgg tctcttgccg gcccttagca
      121 tgagcgagtg ggacccagcc gggtgacatt gtgccggttg gcggatcctc gattgcccct
      181 tttcccgtcc tgctcctccc tcatgaagcg attctgagta cgggggggtt ccggattatt
      241 gttctcacga acccccgctt gtggttgggg ggtatttaat ctgaggcctt agggtccttc
      301 gttgtctttt gagtgttttg tgtgtgtaca tattttgctc ttaagtttat aaatatacat
      361 atattgagag tgtccacgtc tcctcgctga accttaggaa tcctttgcca caatgtcctg
      421 tgtgcactat aaattttcct ctaaactcaa ctacgacacc gtcacctttg atgggctcca
      481 tatctccctc tgcgacttaa agaagcagat tatggggaga gaaaagctga aagctgccga
      541 tagcgatctg cagatcacca acgcgcagac gaaagaagaa tatactgatg ataatgcact
      601 cattcctaaa aattcatctg taattgtcag aagaattcct attggaggtg ttaagtctac
      661 aagcaagaca tatgttataa gtcgaactga accagtgatg ggaactacaa aagcaattga
      721 tgactcttct gcgtctattt ctctggccca gcttacaaag actgccaatc tggctgaagc
      781 caatgcttct gaggaagaca aaattaaagc aatgatgtcg caatctggcc atgaatacga
      841 cccaatcaat tacatgaaga aaactctagt aggcccgcca cctccgtctt atacctgttt
      901 tcgttgtggt aaacctggtc attatattaa gaattgccca acaaacgggg ataagaactt
      961 tgaatctggt cctaggatca aaaagagcac tggaattcct agaagtttta tgatggaagt
     1021 gaaagatcct aacatgaaag gcgcaatgct tacgaacact ggaaaatacg caataccgac
     1081 tatagacgct gggagactcc tctttcacaa attgggaaca atggggcata agcaaattga
     1141 tacttatttg tggaatcgtg gtgatgtcta tggagcagct gcaacacaaa taacacacct
     1201 aagagaggcc tatgcaattg ggaagaaaga gaaaccaccc ttcttaccag aggagccatc
     1261 gtcatcttca gaagaagatg atcctatccc agatgagctc ttgtgcctca tctgcaaaga
     1321 cattatgact gatgccgttg tcattccctg ctgtggaaac agttactgtg atgagtgtat
     1381 aaggacagca ctcctggagt cagatgagca tacatgtcca acatgtcatc aaaatgatgt
     1441 ttctcctgat gctttaattg ccaacaagtt tttacgacag gctgttaata acttcaaaaa
     1501 tgaaactggc tatacaaaaa gactacgaaa acagttacct ccacccccac ctccaatatc
     1561 agcgccaaga ccactcattc agcggaacct gcaacctctg atgagatctc ccatatcaag
     1621 acagcaggat cctctgatga ttccagtgac atcttcctca gctcactcaa ctccctctat
     1681 atcttcatta acttcaaatc catcctcctt ggctccttcc gtgcctggca acccatcttc
     1741 tgccccagct ccagtgcctg atataactgc aacagtatct atatcagtcc actcagaaaa
     1801 atccgatggg ccttttcggg attctgataa taaactatta ccagctgccg cccttgcatc
     1861 agaacactca aagggagcgt cctcaattgc tattactgct cttatggaag aaaagggtta
     1921 ccaggtgcca gtccttggga ctccatcttt gttgggacag tcattattgc atggacagtt
     1981 aatacccaca actggtccag taagaataaa tgctgctcgt ccaggtggtg gtcgaccagg
     2041 ttgggaacat tccaacaaac ttgggtacct ggtttcccca ccacagcaaa ttagaagagg
     2101 agaaagaagc tgttacagaa gtataaaccg cgggcgacac cacagcgaac gatcacagag
     2161 gactcaaggc ccatcactac cagcaactcc agtctttgtg cctgtcccac cacctccttt
     2221 gtatccacct cctccccata cacttcctct tcctccaggt gtacctcccc cacagttttc
     2281 tcctcagttt cctcctggcc agcctccacc agcaggatat agtgtccctc ctccagggtt
     2341 cccgccagct cctgccaata tatcaacacc ttgggtatca tcaggagtgc agactgccca
     2401 ttcaaatacc atccctacaa cacaagcacc tcctttgtcc agggaagaat tctatagaga
     2461 gcagcgacga ctaaaggaag aggaaaagaa aaagtccaag ctagatgagt ttacaaatga
     2521 ttttgctaag gaattgatgg aatacaaaaa gattcaaaag gagcgtaggc gctcattttc
     2581 caggtctaaa tctccctata gtgggtcatc gtattcaaga agttcataca cttactcaaa
     2641 gtcaaggtct ggctcaacac gttcacgctc ttactctcgg tccttcagcc gctcacactc
     2701 tcgctcctat tcacggtcac ccccataccc caggagaggc agaggcaaga gccgcaatta
     2761 ccgttcacgg tccagatctc atggatacca tcgatctagg tcaaggtcac ctccctatag
     2821 acgataccac tcacggtcga gatctcctca agcatttagg ggacagtctc ccactaaacg
     2881 caatgtacct caaggagaaa cagagcgtga gtattttaat agatacagag aagttccacc
     2941 cccttatgat atcaaagcct attatgggcg gagtgtcgac tttagagacc catttgagaa
     3001 agaacgctac cgggaatggg agaggaaata ccgagagtgg tatgagaagt actacaaagg
     3061 gtacgcagtg ggagcccagc ctagaccctc agccaacaga gaggactttt ctccagagag
     3121 actcttacct cttaatatca gaaattcacc ctttacaaga gggcgcagag aagactatgt
     3181 tgctggacaa agtcatagaa atagaaatct aggtggcaac tatccagaaa agatttcgac
     3241 aagagatagt cacaatccaa aagataatcc aaagtcgaaa gagaaggaga gtgaaaatgt
     3301 tccaggagac ggcaaaggaa acaagcataa gaaacacagg aaacgaagaa agggggaaga
     3361 gagtgagagc ttcctgaacc cagagctact ggaaacttct agaaaatcca gggaatcctc
     3421 agggatcgat gaaacaaaga cagatgcact gtttgttctc ccaagcagag acgatgctac
     3481 acctgttagg gatgaaccaa tggatgcaga atctatcacc ttcaaatcag tatctgaaaa
     3541 agacaagaga gaaaaggata aaccaaaagt aaaaagtgac aagaccaaac ggaaaagtga
     3601 tgggtctgct acagccaaga aagaaaatgt tttaaaacct tctaaaggac cccaagacaa
     3661 ggtagatgga gaccgtgaaa aatctcctcg gtctgaacct cctctcaaaa aagccaaaga
     3721 ggaggctaca aaggtcgact ctgtaaaacc ttcctcatct cagaaggatg agaaggtcac
     3781 tggaacccct agaaaagccc actccaaatc tgcaaaagaa caccaggagg caaagccagt
     3841 caaagaggag aaggcaaaaa aggactgttc caaagacatc aagtcagaaa agccagccag
     3901 taaggacgag aaggccaaga agcctgagaa aaataaacta cttgaaagca agggagagaa
     3961 acgaaagaga aaaaccgaag agaagagtgt agattttgag tcctcttcaa tgaaaatctc
     4021 taaagtggaa ggaacagaaa tagtgaaacc atcaccaaag cggaaaatgg aaggtgatgt
     4081 tgaaaagctg gaaaggaccc cagaaaagga caagagtgca tcatcaacta ccccagccaa
     4141 aaaaattaaa ctcaatagag aaactggaaa aaaaattgga aatgcagaaa atccatctac
     4201 tacaaaagaa ccctctgaaa aactggagtc aacatctaac aaaatcaaac aggaaaaagt
     4261 caagggaaag gccagacgga aagtagctgg gacagaaggc cccagctcca cgcttgtgga
     4321 ctacaccagt acaagctcaa ctggaggcag tcctgtgagg aaatctgaag aaaagacaga
     4381 tacaaagaga acagtcatta aaactatgga ggaatataat aatgataata cagcgcctgc
     4441 agaagatgtt ataattatga ttcaggttcc tcagtccaaa tgggataaag atgactttga
     4501 atctgaagaa gaagatgatg ttagaaccac acagcctata cagagtgtag ggaaaccatc
     4561 cagtattata aaaaatgtca ctactaagcc atcagctaca gttaagtgca ctgagaaaga
     4621 aaatgagcag tctgagaaaa ttcagaagct taccaaggag gtcagccatg aggtgataca
     4681 gcatgagctc aggagctcaa agggctctgt gtccagtgag aaggggagag ccaaggaccg
     4741 ggatcactca gcgtcagaga aggacaaccc tgacaagagg aagaccagta tccagccaga
     4801 caaggagagc actgtggacc gcctgagtga gcaaggacat tttaagaatc tctctcagtc
     4861 ttccaaagag accaggactt cagagaagca tgagtctgtt cgtggctcct caaataaaga
     4921 cttcactcct ggtagagaca agaaaacgga ctacgacagc agagattatt ccagttccaa
     4981 acgaagagac gaaagaagtg aattaacaag aagaaaagac tctcctcctc ggagtaaaga
     5041 ttctttatct ggacagaaaa gtaagctgag ggaggagaaa gatttaccta aaaaggggac
     5101 agagttaaaa aaaagtaatt ctagtccccc aagagacaaa aagcctcatg atcataaagc
     5161 ctcctatgaa accaaacgct catgtgaaga gacaaagtct gtagataaaa atgctgggaa
     5221 ggaacgggag aagcatgctg ctgaagcttc tcgaaacggg aaagagtcca gtggcagcaa
     5281 gttgccatct atacccaacc cgcctgaccc tcccatggaa aaggagctgg ctgccgggca
     5341 gattgagaag agcaccatca agccaaaacc ccagttgagt cattcctcaa ggctttcctc
     5401 tgatctcact agagagactg atgaggctgc ttttgaaccc gactataacg agagcgatag
     5461 tgagagtaat gtgtctgtga aggaggaaga agctgttgcc agtgtctcca aggacttgaa
     5521 agagaaagca acagagaaag caacagagag cttgaatgta gcaacagcca gccagccagg
     5581 tgcagacagg agccagagcc aaagtagccc cagtgttagt ccaagtagaa gtcatagccc
     5641 ttccggcagc cagacccgga gccacagcag cagtgccagc tcggcagaaa gccaagacag
     5701 caaaaagaag aaaaagaaga aagacaagaa aaagcacaag aagcataaaa agcacaagaa
     5761 gcacaagaag catgcaggcg tggacggtga tgtggagaag agccagaaac ataaacacaa
     5821 gaagaagaag gcgaagaaaa acaaagacaa ggagaaggag aaagatgacc aaaaagtgaa
     5881 atctgtcact gtgtgaagga cggatgtttt aattgactta attactaagt catctgtatt
     5941 aaattctgtt ataatgtaaa gagattccag ccttgtaaat aatgaatgga agaccctgtg
     6001 ctgcacttaa agtatttgct gcttgattat ttcattttta catcagagct ttataacgaa
     6061 cttttgtaca gaattgtgag ttgtgaccat ggaacatgag aggttttgct agggcctatt
     6121 atttttaacc accattaatt agttggggtg gagtttactg tgaaattttc acatttgaat
     6181 ttttttaatt gcctggcaaa tgctgatatc agttcaaaaa tatcagcaga atgatttgct
     6241 gaactcatta cagccccgtt atgtcacttt ttgattacaa taaaagtttt cagtaaactt
     6301 ttcacttgtt gaaaatgtat attatttaaa gatagtagtg tctcatttct tctctttcca
     6361 agatcctttg agcctgtaag tcaagctgac tagacaaaat tctcaacgtt gaaaatgtac
     6421 ttcagagggg gctggtggaa gatcgttgtt cttaataatt agaagctagg tttctaaaag
     6481 gagggcaggg tgcttaactc tcagtgatga ggaattgggc tgttctagct gtatggtttt
     6541 cttggaattc tgggttggta ttaaattcct taatgaaaca gaatccgctt aaaatgtgtg
     6601 gctgtgtcca ctgtctgtcc tgctgacaag catgtactgt gaggctggag gggggtcttc
     6661 actactacgt ctgtctggag ctcagtgaag gcactcaagg atttggacag gttatgtggt
     6721 tttagagaac ctggcaaaga tagggctggt cctatggtta aactgctagt ctgctgtccg
     6781 gtgcagtagc cgagggtttt ggtggtggaa tcaaaacgca ggcacatcta gcagcaaggt
     6841 gcgtggagtg tcgtgtacat ggtacttaca taattgctgg ttctctggtg cttgggtcaa
     6901 gacacttgaa tgtcgagttt taccatttaa aattctaagt gataacccct cccccctttt
     6961 ttctgtttta aagtgtgtgt gtccatggag ggagaggaga gcattggagc cctctaacca
     7021 gctggagtca caggtagttg tgagctgcct gatgtggatg ttgggaacca aattcaggtc
     7081 ctatgcaaga gcaacaagcg cttgccacca ctgagccaaa gtaacactag tgctacagat
     7141 gtggaagtca tccagagatg ctgcctttga gccagatcag ctttgctggg gcagctcagc
     7201 tctgccctga tgtcaagcgc acacacctat gccagggcta agctgtcctg accatttatg
     7261 cccacgtgca gcatactccc tctttaattg gaggtagtcc agcaagatta tattcttact
     7321 tcctactgat gagatctact actcgatcct gtttcccaca ctgactaaag atttggtaca
     7381 cagaactgtc aaatctgaac tggttactca cattattgag ctcattcttg aagctcaccc
     7441 agccttcact ttaattgcag ctccactcct gtaacaggtt cctggctacc gatcacctca
     7501 aagtgttgtt ccttttgcaa cgaagagcag tttcccagct ttgttggtgt ttgaacttag
     7561 tttctttcat atgctgaatg ttgttcaaca gaaacatgca aaggctagag acatggctca
     7621 atctgagtta agtgcttcca taagcctgag gacttgagtt caaatctcta aaacacaagt
     7681 aagtctagat gctgtgcgtg catccgtaac tccagtgttc tacagtgaga tgctacaatg
     7741 agatggcagg tagagacctg tatgccacaa acaaaagaca ctgactcaag ggggaagggc
     7801 caaccccagg gttgcccttt aatgacggcg ctgtggtaca tgtgtatcca ctcccagaaa
     7861 catacatgat acagattttt tttaaatgta tgaatgtagc atttggaggt aacttgaaat
     7921 actactcaat aaatggtctt ggttttaatt aatatttgtt aggcactgcc aggtgctctg
     7981 tactttctat aaccattaaa aatgcccatg gcccttgatg gta
//
