LOCUS       NM_001037096            4939 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus Ras association domain family member 2 (Rassf2),
            mRNA.
ACCESSION   NM_001037096 XM_230543
VERSION     NM_001037096.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4939)
  AUTHORS   Song,H., Kim,H., Lee,K., Lee,D.H., Kim,T.S., Song,J.Y., Lee,D.,
            Choi,D., Ko,C.Y., Kim,H.S., Shin,H.I., Choi,J., Park,H., Park,C.,
            Jeong,D. and Lim,D.S.
  TITLE     Ablation of Rassf2 induces bone defects and subsequent
            haematopoietic anomalies in mice
  JOURNAL   EMBO J 31 (5), 1147-1159 (2012)
   PUBMED   22227519
REFERENCE   2  (bases 1 to 4939)
  AUTHORS   Ohta,S., Bukowski-Wills,J.C., Sanchez-Pulido,L., Alves Fde,L.,
            Wood,L., Chen,Z.A., Platani,M., Fischer,L., Hudson,D.F.,
            Ponting,C.P., Fukagawa,T., Earnshaw,W.C. and Rappsilber,J.
  TITLE     The protein composition of mitotic chromosomes determined using
            multiclassifier combinatorial proteomics
  JOURNAL   Cell 142 (5), 810-821 (2010)
   PUBMED   20813266
REFERENCE   3  (bases 1 to 4939)
  AUTHORS   Song,H., Oh,S., Oh,H.J. and Lim,D.S.
  TITLE     Role of the tumor suppressor RASSF2 in regulation of MST1 kinase
            activity
  JOURNAL   Biochem Biophys Res Commun 391 (1), 969-973 (2010)
   PUBMED   19962960
REFERENCE   4  (bases 1 to 4939)
  AUTHORS   Cooper,W.N., Hesson,L.B., Matallanas,D., Dallol,A., von
            Kriegsheim,A., Ward,R., Kolch,W. and Latif,F.
  TITLE     RASSF2 associates with and stabilizes the proapoptotic kinase MST2
  JOURNAL   Oncogene 28 (33), 2988-2998 (2009)
   PUBMED   19525978
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Apr 23, 2021 this sequence version replaced NM_001037096.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC107656.1, SRR26643292.14621.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-185               JAXUCZ010000003.1  139733184-139733368 c
            186-276             JAXUCZ010000003.1  139715032-139715122 c
            277-352             JAXUCZ010000003.1  139712147-139712222 c
            353-504             JAXUCZ010000003.1  139709998-139710149 c
            505-593             JAXUCZ010000003.1  139707967-139708055 c
            594-754             JAXUCZ010000003.1  139706958-139707118 c
            755-856             JAXUCZ010000003.1  139705292-139705393 c
            857-908             JAXUCZ010000003.1  139703780-139703831 c
            909-1030            JAXUCZ010000003.1  139703111-139703232 c
            1031-1128           JAXUCZ010000003.1  139702469-139702566 c
            1129-4939           JAXUCZ010000003.1  139697187-139700997 c
FEATURES             Location/Qualifiers
     source          1..4939
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..4939
                     /gene="Rassf2"
                     /note="Ras association domain family member 2"
                     /db_xref="GeneID:311437"
                     /db_xref="RGD:1305551"
     exon            1..185
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            186..276
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             218..1198
                     /gene="Rassf2"
                     /note="Ras association (RalGDS/AF-6) domain family 2; Ras
                     association (RalGDS/AF-6) domain family member 2"
                     /codon_start=1
                     /product="ras association domain-containing protein 2"
                     /protein_id="NP_001032173.2"
                     /db_xref="GeneID:311437"
                     /db_xref="RGD:1305551"
                     /translation="MDYTHQTALIPCGQDKYMPKSELLLHLKTYNLYYEGQNLQLRHR
                     EEEDEFIVEGLLNISWGLRRPIRLQMQDDHERIRPPPSSSSWHSGCNLGAQGTTLKPL
                     TVPTVQISEVDMPVENMETHSPTDSRGLKPVQEDTPQLMRTRSDVGVRRRGNVRTSSD
                     QRRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRINSTMTTPQVLKLLLNKFKIENSA
                     EEFALYVVHTSGEKQKLKNSDYPLIARILQGPCEQISKVFLMEKDQVEEVTYDVAQYI
                     KFEMPVLKSFIQKLQEEEDREVEKLMQKYTVLRLMIRQRLEEIAETPETI"
     exon            277..352
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            353..504
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            505..593
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            594..754
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            755..856
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            857..908
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            909..1030
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1128
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..4939
                     /gene="Rassf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggggcggag gggccaggtg ggcggggcgc ccgccctcag ccgcactgtc gccgcccaga
       61 ccggcccaag cgagccggtc ccgcggatca ctggccaagc acgctggagc acccccaccc
      121 ccgcagcggc gcccccactt tccaacccct gcggcgagag cggatgcaga tggtcccgga
      181 cacaggcctc tacttctgat gaaaagagga gggaagaatg gactacactc accaaactgc
      241 cctaattcca tgcggacaag acaagtacat gcccaagagt gaacttctcc tacatttaaa
      301 gacatacaac ttgtactatg aaggccagaa cctgcaactc cgacaccgag aggaagaaga
      361 cgagttcatt gtggaggggc tgctgaacat ctcctggggg ctgcgcaggc ccattcggct
      421 gcagatgcag gatgaccacg aacgcatccg tcccccacca tcctcctcct cctggcactc
      481 cggctgtaac ctgggtgcac agggcaccac actgaagccc cttaccgtgc ccactgtcca
      541 gatctcagaa gtggatatgc ccgttgaaaa catggagacg cacagcccaa cagattccag
      601 aggcctgaag cctgtgcagg aggacacccc acagttgatg cgcacacgca gtgatgttgg
      661 ggtgcgccgc cgtggcaatg tgagaacatc cagtgaccag cggcgaatca gacgccatcg
      721 cttctccatc aatggccatt tctataacca caagacatca gtgttcacac cagcctatgg
      781 ctctgtcacc aatgtccgca tcaacagcac catgacaact ccgcaggtcc tgaagctgct
      841 gctcaacaag tttaagattg agaattcggc agaggagttc gcgttgtacg tggtccacac
      901 cagtggtgag aagcagaagc tgaagaactc tgactacccc ctgattgccc gcatcctcca
      961 gggcccctgt gagcagatct ccaaagtttt tctgatggag aaggaccagg tggaggaggt
     1021 cacctatgat gtggcccagt atataaagtt tgagatgcca gtccttaaaa gcttcattca
     1081 gaaactccag gaggaagaag accgggaggt ggagaagctg atgcaaaagt acacggtgct
     1141 ccggctaatg attcggcaaa ggctagagga gatagcagag acccctgaga ctatctgagc
     1201 catgggaata aaggcaatcc agacactcca gggcccgagg ctgacctgag aagacccatg
     1261 ggaagctaga cactgtcctt ccacagaaac gttttcacac gaaccttgca gccctccgaa
     1321 agccagtact gctcctacag taggacctac aagcagcaga cggctcccca tctctggatc
     1381 cctgctcctc ttggtttcat tctgaaagac cttcatccta aggaggaccc acaatgtgta
     1441 tgctcacata cctgagtgtg cacatgtgtg cgtatgtgcg ctacacacgc aagcgtgcat
     1501 atgtgtactt actatgtcca tgcgcctccc tgatgttctt acatttggtt aaattctgag
     1561 caggtgccgt gaggctggcg cacaaactgc ttctgcgcag gaggaacggg gggtgactga
     1621 ggcttcttgc ctcttccagt gccaacggca gccacacaga tctgacaggg aagaggaggc
     1681 cgcgggctca ccgtttggaa cgcctgaagg tttatagcag agattgttct catttgccaa
     1741 ggaggatggg tgaccctgag atctttggga attagtcaaa gtgacaaccc cacgccctgg
     1801 gggcaaggcc aatgaaatgg caaagcaaga tcaccttggg gcagatacac tgagtctgtg
     1861 agtttttgca ctggaaaggt tatcgttgta caaagcacaa ttaatgtcct gtcctatgtg
     1921 gacccctgga aagaagggat tctgattttg ttcttggctt tgtggatgct tctgggtatt
     1981 tcttctctcc agctgacact cgaattcatt ctgacctgct catgtaccta gaccgggtgt
     2041 gtgctgggat aaatggcact cgtagactgg agggaaggtc acaggtgcca ccatcacatc
     2101 agtaagagta tcccccacgt ggagctgggg cattgtgttt gaaattacat ggttttcttt
     2161 ccggcctttg cacacttgta agctccttca ctttatacat ggagatggat tccaagaatg
     2221 gagacctgtc ctgttcactc aacataggga agctctttgg ggagttccat gcgtgtgggc
     2281 agagaggata gtgcttgctt agcctttgag aggccatggt ttttagaacc agtctcattg
     2341 gcagaaaaga gcagggatga tcctgtagtc cctccatttg ggacgctgcc atgtagctgg
     2401 tcacctgagt gacttgtacc atttgaggtt ggacagatgg atactagggc cttgctgctg
     2461 gtctatgaaa ctcgaccaag caagatgagc agcccgtaac tcaggcatct ctgagtcttg
     2521 ctacaacagg atgccctttc ctacctgccc tcaagaaagc tctagaagca tggcagctaa
     2581 gggccctgac cagtgtgcct tttaaggaag gtggaactct gccgcagata tcttcctggg
     2641 taggagtgtt actgtccttc actctcctca gaaggttcac ggctgtggcc tcactgtggt
     2701 cagccatttt gctgggtatc atttagcacc ctagctcctc ttctagggca gcacaatgca
     2761 tcccatgagc agtgggatgg aaacccagtg gttcttagtc tctatcacag actccaaaga
     2821 cagcaaagca cagagctggg gctggggatg cagctctcct tatgagcaca actgaactca
     2881 gtgggcaact ggggtggggg ttcctttact acagacaaag aacagctttg tgaatgcaaa
     2941 tatctgagaa agtttgattt ggataatttc tctcccagtt atctttatct tgaatgttca
     3001 gagcctatgt tgatccacac ttctccctcg ggaacttggg gggtttccac ggagcacact
     3061 aactgactgg gaagttattt ctgatttatg aaagctcagt gtgatagtgt caacacgtga
     3121 ctgtttctga gtgtcaggtt gccaggctct ccaaggtggt ggtgccaagg tagatggcct
     3181 ttaaagtatg gggttcagaa agggagttgg ggtccatgct cactaatcca tctcggcaca
     3241 tcccctaaag atcatttctc acacccaaag aactaattag gagtttttag gaaattgact
     3301 ggggctgaga ctcagtggta gagcattttc taagtgtgtg tcaaaagtag cacagtctaa
     3361 cacacacaca cacacacaca cacacacaca cacacacaca cacacaagta aaaagaaaaa
     3421 aaggaagcaa gcaagcaagc agccgtagcc cagtggtaga ggggttcttg gagtgttagg
     3481 gcctggtgcc tgaaacctgc accaagctcc actctaccct gtgaacctgg gaaacctttg
     3541 acagagccgc agcagaacag accactacag tggcgaccgg attttcttgc tggtctcact
     3601 tcgcagcttt gaactccaag accgatcgat tagtgtgggc ttacgtaatt gagcgcaatg
     3661 gacctgaaat cgggaggaat aaaagactaa tgcaaggcag tggtgggggt gttaatccaa
     3721 caggtgaaaa gtggttcgcc tgcctctgga ctcttcccct cccctgctct ccacaaaggc
     3781 ttatgttaca aggtgaccaa gtgaacactg gcgtcggtct gagggaggtg gtgatgtcag
     3841 gcataggttc gctttcttgg tggccaggtt agtggggagg tgaggcctca cagcaggtgg
     3901 gggtgttagt tggaaagacc agccatgcct gtgctactga tgaagggcac actgctgaca
     3961 caccggacaa gtgcagcttg gagccgaggc tggggagaga cgacctcagc aggacagtgg
     4021 cgcagcccaa gaccgggatg ttggcctgag gcaagctgat ggtttgggaa gaaatattca
     4081 caactttctc ctttcctatt tctagaaact tccagataaa gaaattttat cagtgccata
     4141 tgatggtcct ccaatatctg caaaagcatc tcggcaagga ttgtgttttg tggttttgag
     4201 tgtgtatttg atgtcaggag ggtagataag gaatctggtc aaacagggca agaagcattc
     4261 aaggaatgac agaaacagcg aagcctcaaa gcaaaaccca aattctgttt gaagctttgt
     4321 aacatggaga acttggggtt agggatacat ttccaagaaa gaaatatgtc cgtgaccaaa
     4381 ggagttttaa tgtcccacag gaataagctt ggccctgtgt gagggaggag gcaggaggct
     4441 gtcctagctc acttactccc acagcactgc ctgttttaaa gtttcttact taacttgttt
     4501 tctgtaaagc ctggcttccg ccagatagga gagcatctat aaacctgacg tgacatcccc
     4561 tctctcagac ataattgaaa gtgttcacca tatcttgggt tacacctccc acccttcctc
     4621 ctactcccat gaaactgagc acagaggtgc ttaagctgtg aacttttgag aagccttagt
     4681 ttccaggacg ctgggttctg ggggtactac tagtgtttct tcagttttcc ctcttagttg
     4741 ggtagagtct ttttttcctc gtcataactt gcgtattagg aatggtacat gacttggttc
     4801 aactgtcggt tatgaactga aaaatcggat gttagggcat cttaacacga ttggatgagg
     4861 cctcagtggg gagccatggt tttgcaacct tttaattttg tcttagacct tatttaaata
     4921 aagcactttt agaagcgag
//
