LOCUS       NM_001106261            3191 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus Ras interacting protein 1 (Rasip1), mRNA.
ACCESSION   NM_001106261 XM_001080759 XM_006229030 XM_214916
VERSION     NM_001106261.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3191)
  AUTHORS   de Kreuk,B.J., Gingras,A.R., Knight,J.D., Liu,J.J., Gingras,A.C.
            and Ginsberg,M.H.
  TITLE     Heart of glass anchors Rasip1 at endothelial cell-cell junctions to
            support vascular integrity
  JOURNAL   Elife 5, e11394 (2016)
   PUBMED   26780829
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3191)
  AUTHORS   McKnight,N.C., Jefferies,H.B., Alemu,E.A., Saunders,R.E.,
            Howell,M., Johansen,T. and Tooze,S.A.
  TITLE     Genome-wide siRNA screen reveals amino acid starvation-induced
            autophagy requires SCOC and WAC
  JOURNAL   EMBO J 31 (8), 1931-1946 (2012)
   PUBMED   22354037
REFERENCE   3  (bases 1 to 3191)
  AUTHORS   Xu,K., Sacharidou,A., Fu,S., Chong,D.C., Skaug,B., Chen,Z.J.,
            Davis,G.E. and Cleaver,O.
  TITLE     Blood vessel tubulogenesis requires Rasip1 regulation of GTPase
            signaling
  JOURNAL   Dev Cell 20 (4), 526-539 (2011)
   PUBMED   21396893
REFERENCE   4  (bases 1 to 3191)
  AUTHORS   Xu,K., Chong,D.C., Rankin,S.A., Zorn,A.M. and Cleaver,O.
  TITLE     Rasip1 is required for endothelial cell motility, angiogenesis and
            vessel formation
  JOURNAL   Dev Biol 329 (2), 269-279 (2009)
   PUBMED   19272373
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Feb 10, 2022 this sequence version replaced
            XM_006229030.4, NM_001106261.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.2462.1,
                                           SRR26643287.1167.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-97                JAXUCZ010000001.1  105233599-105233695
            98-238              JAXUCZ010000001.1  105233864-105234004
            239-903             JAXUCZ010000001.1  105234530-105235194
            904-1259            JAXUCZ010000001.1  105236102-105236457
            1260-1913           JAXUCZ010000001.1  105238887-105239540
            1914-1951           JAXUCZ010000001.1  105241377-105241414
            1952-2103           JAXUCZ010000001.1  105241580-105241731
            2104-2219           JAXUCZ010000001.1  105241836-105241951
            2220-2463           JAXUCZ010000001.1  105242947-105243190
            2464-2636           JAXUCZ010000001.1  105243312-105243484
            2637-2784           JAXUCZ010000001.1  105244756-105244903
            2785-3191           JAXUCZ010000001.1  105245622-105246028
FEATURES             Location/Qualifiers
     source          1..3191
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..3191
                     /gene="Rasip1"
                     /note="Ras interacting protein 1"
                     /db_xref="GeneID:292912"
                     /db_xref="RGD:1305291"
     exon            1..97
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            98..238
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..2984
                     /gene="Rasip1"
                     /codon_start=1
                     /product="ras-interacting protein 1"
                     /protein_id="NP_001099731.2"
                     /db_xref="GeneID:292912"
                     /db_xref="RGD:1305291"
                     /translation="MLSGERKEGGSPRFGKLHLPVGLWINSPRKQLAKLGRRWPSAAS
                     VKSSSSDTGSRSSEPLPPPPPPHVELRRVGAVKAAGGASGSRAKRISQLFRGSGAGGA
                     GGPGTPGGAQRWASEKKLPELAAGVAPEPPLPTRAAVPPGVLKIFAAGLASGANYKSV
                     LATERSTARELVAEALERYGLTGGRGAGDSGCVDAYALCDALGRPAAGVGGGEWRAEH
                     LRVLADAERPLLVQDLWRARPGWARRFELRGREEARRLEQEAFGAADADGTNAPSWRT
                     QKNRSRAASGGAALASPGPGSGSGTPTGSGGKERSENLSLRRSVSELSLQGRRRRQQE
                     RRQQALSMAPGAADAQMVPTDPGDFDQLTQCLIQAPSNRPYFLLLQGYQDAQDFVVYV
                     MTREQHVFGRGGPSSSRGGSPAPYVDTFLNAPDILPRHCTVRAGPEPPAMVRPSRGAP
                     VTHNGCLLLREAELHPGDLLGLGEHFLFMYKDPRAGGSGPARPPWLPARPGAAPPGPG
                     WAFSCRLCGRGLQERGEALAAYLDGREPVLRFRPREEEALLGEIVRAAASGAGDLPPL
                     GPATLLALCVQHSARELELGHLPRLLGRLARLIKEAVWEKIKEIGDRQPENHPEGVPE
                     VPLTPEAVSVELRPLILWMANTTELLSFVQEKVLEMEKEADQEGLSSDPQLCNDLELC
                     DEALALLDEVIMCTFQQSVYYLTKTLYSTLPALLDSNPFTAGAELPGPGAELEAMPPG
                     LRPTLGVFQAALELTSQCELHPDLVSQTFGYLFFFSNASLLNSLMERGQGRPFYQWSR
                     AVQIRTNLDLVLDWLQGAGLGDIATEFFRKLSIAVNLLCVPRTSLLKASWSSLRTDYP
                     TLTPAQLHHLLSHYQLGPGRGPPPAWDPPPAERDAVDTGDIFESFSSHPPLILPLGSS
                     RLRLTGPVTDDALHRELRRLRRLLWDLEQQELPANHRHGPPVAATP"
     exon            239..903
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            904..1259
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1260..1913
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..1951
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1952..2103
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2104..2219
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2220..2463
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2464..2636
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2637..2784
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2785..3191
                     /gene="Rasip1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggagcttgg gcagaggaaa acactttaca gagggattgg gacttaacgg aggccaacgg
       61 caccagggcc tccgggtgct acaggacccg aagcaggggc catgctatct ggtgaacgaa
      121 aggagggcgg aagcccccgc tttgggaagc tccatctccc tgtgggcctg tggatcaatt
      181 ccccaaggaa acagctcgcc aaactggggc ggcgctggcc tagcgctgcc tctgtcaagt
      241 cctcgtcctc cgacacgggg agccgcagca gcgagcccct gccgccaccg ccgccgccgc
      301 acgtggagct gcggcgcgtt ggtgcggtga aggcggcggg gggcgcctcg ggcagccgag
      361 ccaagcgcat ctcgcagctg tttcggggct cgggggccgg cggcgccggg ggtcctggca
      421 cgcccggggg cgcgcagcgc tgggccagcg agaagaagct gcctgaactg gcggcgggtg
      481 ttgctccgga gcccccgttg cccacgcgcg ccgcggtgcc cccgggagtg ctcaagatct
      541 tcgcggccgg gctggcgtcg ggcgccaact acaagagcgt gctggctacg gagcgatcta
      601 ccgcgcgcga gctggtggcg gaggcgctgg agcgctacgg gttgacgggc ggccgcggag
      661 cgggcgacag cggctgcgtg gacgcctacg cgctttgcga cgctctgggc cgacccgccg
      721 ctggcgtggg cggtggcgag tggcgcgcgg agcacctgcg ggtgctggcc gacgccgagc
      781 gccccctgct ggtgcaggac ctgtggcgcg cgcggccggg ctgggcgcgg cgctttgagc
      841 tgcgcggccg cgaggaggcc cgtcggctgg agcaggaggc cttcggtgct gcggatgcag
      901 acggcacaaa cgccccatct tggcggaccc agaagaatag gtctcgggca gcatctggcg
      961 gggcagcttt ggccagtcct ggtccaggat caggatccgg gacccccact gggtccgggg
     1021 gcaaggagcg atctgaaaat ctgtcgctgc gtcgaagtgt gtctgagctg agtctacagg
     1081 ggcggaggcg gaggcagcag gaacgcaggc agcaggcact tagcatggcc ccaggggcgg
     1141 ctgatgctca gatggtgcca acggaccctg gagactttga ccagttgact cagtgcctca
     1201 ttcaggcacc cagcaaccgt ccttacttcc ttctgctcca gggctaccag gatgctcagg
     1261 acttcgtggt gtatgtgatg acacgagagc agcacgtgtt cggccgaggt gggccctcgt
     1321 cgtcccgcgg cggatcccct gccccatatg tggacacctt cctcaacgcc ccagacatcc
     1381 tgcctcgaca ttgcacggtg cgcgcgggtc ctgagccccc agctatggtg cgcccatccc
     1441 ggggcgcccc ggtcacacac aatggctgcc ttttgctgcg cgaggcagag ttgcatcccg
     1501 gagacctgct aggcctggga gagcatttcc tgttcatgta taaggacccc cgcgccgggg
     1561 gctctggtcc cgctcggcca ccctggctgc ctgcgcgccc cggggccgcg ccaccgggtc
     1621 cgggctgggc cttttcttgt cgcctgtgtg gccgtggcct gcaggagcgc ggcgaggcac
     1681 tggctgccta cctggacggc cgcgagccgg tgctgcgctt tagaccacga gaggaagagg
     1741 cgctgttggg agagatcgtg cgcgctgcag cctcgggcgc aggagacctg ccaccactcg
     1801 ggcccgccac tctgctggca ctgtgtgtgc agcattcggc gagggagcta gagctgggcc
     1861 acctgcctcg cttgctgggc cgcctggccc ggctcatcaa agaggccgtt tgggaaaaaa
     1921 ttaaagaaat tggagaccgc cagccagaga accacccaga gggagttcct gaggtgcctc
     1981 tgaccccaga ggctgtgtct gtggagctga gaccgctcat actgtggatg gccaatacca
     2041 cagagcttct gagctttgtt caggagaaag tgctagagat ggagaaagag gctgaccagg
     2101 agggcctgtc ctccgaccct cagctctgca atgatttgga attgtgtgac gaggccttgg
     2161 ccctcctgga tgaggtcatc atgtgtacct tccagcagtc cgtctactac ctcaccaaga
     2221 ctctctattc gacactgcca gctctcctgg acagtaaccc tttcactgcc ggggcagagt
     2281 tgccggggcc tggtgcagag ctggaggcca tgccacctgg actcaggcct accctgggtg
     2341 tgttccaggc agctctagaa ctgaccagtc agtgtgagct gcatcccgac ctcgtgtccc
     2401 agacttttgg ctacttgttc ttcttctcca atgcatccct tctcaactcg ctgatggaac
     2461 gaggtcaagg ccgacctttc tatcagtggt ctcgagccgt ccaaatcaga accaacttgg
     2521 atctcgtttt ggattggctg cagggggccg ggctgggtga cattgccact gagttcttcc
     2581 ggaagctctc cattgccgtg aacctgctgt gtgtaccccg tacctccctg ctcaaggctt
     2641 catggagcag cttacggact gactacccca ccttgactcc tgctcaactc caccatctcc
     2701 tcagccacta ccagttgggt cctggccgcg gaccaccacc agcttgggac ccaccacctg
     2761 cagagcgaga tgctgtggac acaggggata tctttgaaag tttttcctcg catcctcctc
     2821 tcatcctacc cctgggtagc tcacgcctgc gcctcacggg cccagtgaca gatgatgcat
     2881 tacaccgaga actacgcagg ctccgtcgcc tcctctggga tcttgagcag caggagctgc
     2941 cagccaatca tcgccatgga ccgccggtgg ctgcgacacc ttgaaaacca atgacaaaga
     3001 aacgcgcgca acttgaaatt gcaccggttt ttaagggagc ccgcctgggt gtagagcatt
     3061 ttgggagttg tagttttccc cgagcagacc gctgagagtt tgacttgttg ggttggtaga
     3121 tgatcggaca atgggaagat gggcttggga tgtgaattcc aagaagtaat aaaagtatct
     3181 gtggtattga c
//
