LOCUS       XM_017599427            3931 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus RasGEF domain family, member 1B
            (Rasgef1b), transcript variant X1, mRNA.
ACCESSION   XM_017599427
VERSION     XM_017599427.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051349.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017599427.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017599427.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3931
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3931
                     /gene="Rasgef1b"
                     /note="RasGEF domain family, member 1B; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 12 ESTs, 10 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     22 samples with support for all annotated introns"
                     /db_xref="GeneID:100361238"
                     /db_xref="RGD:1562220"
     CDS             997..2628
                     /gene="Rasgef1b"
                     /codon_start=1
                     /product="ras-GEF domain-containing family member 1B
                     isoform X1"
                     /protein_id="XP_017454916.1"
                     /db_xref="GeneID:100361238"
                     /db_xref="RGD:1562220"
                     /translation="MAKFLAALLGCTLRSKGSSPMLEGTIFSTLAGEKSSSDYKKEQQ
                     WKPVYYSLATMCLSNPLIEKPGGKESMPQTPPFSAMFDSSGYNRNVYQPSEDSCGGLN
                     YHDNNLLSGSLEALIQHLVPNVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEH
                     QRLSEGDGDKNQTRKIAPKILQLLTEWTETFPYDFRDERMMRNLKDLAHRMASGEEQT
                     YRKNVQQMMQCLIRKLAALSQYEEVLAKLSSTATDRLTVLKAKPQSIQRDIMTVCSDP
                     YTLAQQLTHIELERLNYIGPEEFVQAFVQKDPLDNDKNCYSERKKTRNLEAYVEWFNR
                     LSYLVATEICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKK
                     TWAKVKTAKFDILEHQMDPSSNFLNYRTALRGAAQRSLTAHSSREKIVIPFFSLLIKD
                     IYFLNEGCVNRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKVLQYLLSVPVF
                     SEDALYLASYESEGPENNIEKDRWKSLRASLLGRV"
ORIGIN      
        1 ccagacttct tgcagctcag gacttcttgt tttaaacaaa cgtcacgggt cacccacagt
       61 acactaagtg ggagttacag ctgtcagcag taaaactcga tcgagtgcaa agctggccgg
      121 gtttcttgga agaacaacag gccgcacctg tgtgtagcag tgtccagctt tgcccatccc
      181 gggccctcct gcctgggagg caggccaagg acagagtgat caccctcttc cctttagggt
      241 ttacttgtgc agatctcacc tagtgacagg ggctcgcacg tgacaggagc tgggttctta
      301 atccacggtt tggaaccatc tccttccaca ctggaagggt ggggctggcg cgggccggag
      361 tagggagcct tgtggatagc tcgagttctg ccttggtaac tcgccaaatg tcagtggacc
      421 tgggtcccct cctctcccac ctgcattgtc acaaatcggg cagaaactag ggaagtgggt
      481 cacccgggcg actccggtga acagcccctc ccgccttggt cgcaagctgt cagcgcagcc
      541 ccaggcttcg gctcccactg gcggcggcgg cgtctgcatc tctgcctatg ggcgggcctg
      601 gctgtcgctg cgtcgctgct ctgggctcgc cgccgccctt gcccccgcgc caccgtgggt
      661 cgtgcgctgt tggccctcct gacaccccct cggcggggcc cttcccttta ctacggcgtt
      721 agtgacattc agctggtgag gcgagcgcag ccccagctcc cgcggcgcgg aggcaggggc
      781 gcccgcggct acctgctcct ctcacccggg cacctctgga gccgcagcgg cgagctcccc
      841 gcaggcccgg agacccccga cgggacgacc ttggcgggag gatccccgcc cccacccggg
      901 tccaggagct tcggtccgcc ctgcccaccc cagctctggc aagggtcgag gaccgaggcg
      961 gcgagcgcga gggggactct gcctccctgc tcgtatatgg caaagtttct cgcggcgctc
     1021 ctgggctgca cactgcggag caagggttcc tctcccatgc tggagggcac catttttagc
     1081 acgctggctg gtgagaagtc ctcttccgac tacaaaaagg agcagcaatg gaaaccggtg
     1141 tactacagtt tggccaccat gtgcctttcg aatcctctca ttgagaagcc aggaggcaaa
     1201 gaaagtatgc ctcagacacc tcccttctca gcaatgtttg acagcagcgg ttacaaccgg
     1261 aacgtctacc agccttcaga ggacagctgt gggggcctga actaccacga caataacctc
     1321 ctttcagggt ccctggaagc gctcatccaa cacttggtgc ccaatgtgga ctactatcct
     1381 gataggacat acatattcac cttcctgcta agctcccggt tgttcatgca tccctacgaa
     1441 ctcatggcca aggtttgcca cttgtgcatt gagcaccagc ggctgagcga gggggacggt
     1501 gataagaacc agacgaggaa aattgcaccg aaaattcttc aactcttgac agagtggaca
     1561 gaaacgtttc cttatgactt ccgggatgag agaatgatgc ggaaccttaa ggacctggcg
     1621 cacaggatgg ccagtggcga ggagcagacg taccggaaga atgtccagca gatgatgcag
     1681 tgtctgatcc gaaaactcgc ggccctgagc cagtacgagg aagtcctggc caaactcagc
     1741 tccacggcca cagaccggct cacggtcctg aaggccaagc cccagtccat acagcgggac
     1801 atcatgaccg tctgcagcga cccttacacg ttggcccagc agctgactca cattgagctg
     1861 gagagactca attacattgg cccagaagag ttcgttcagg cgtttgtgca gaaggaccct
     1921 ttggacaatg ataagaattg ctacagtgaa cggaagaaaa cacggaactt agaagcttac
     1981 gtagagtggt ttaatcggct aagctacttg gttgccacgg aaatctgcat gcctgtgaag
     2041 aagaaacacc gagcgaggat gatcgagtat ttcatcgacg tggctcgaga gtgtttcaac
     2101 ataggaaact tcaactcctt gatggcaatc atctctggta tgaacatgag tccggtctcg
     2161 cgacttaaga aaacctgggc caaagtgaag accgcgaagt tcgacattct tgagcatcag
     2221 atggatccgt caagcaactt ccttaactac aggacagctc tccgaggggc agcgcaaagg
     2281 tccctcactg cccacagtag cagagagaag attgtgatac cattcttcag tctcttaatc
     2341 aaagacattt atttcctcaa cgagggctgt gtcaaccgtc ttccaaatgg ccacgtcaat
     2401 tttgagaaat tttgggaact ggccaaacaa gtgagtgaat ttatgacatg gaaacaggtg
     2461 gagtgtccgt tcgagcggga ccggaaggtc ttacagtacc tgctctcagt gcccgtattc
     2521 agtgaagacg ctctctactt ggcttcatat gagagtgaag gacctgaaaa taatatagag
     2581 aaggacagat ggaagtcttt aagggccagc ctcttgggca gagtttagca caaggaaaat
     2641 gcttctgttc ctgcatcaga cagaccccgg aggggctggc cttgttttct ggcatccagt
     2701 actaggaact gtccctcgga ctgcaggcaa gcccagctgt cgatccggat ggggaatcca
     2761 tttcccacag cggacagatt gacttggatt gttttttttt tttttttttt tttttttgga
     2821 gactgaaatc ttcactgaag acacttgaga aagaatcctc taagagtccc agctctgcgt
     2881 atgattcatc ttctggaatt tccacgtgaa tcacagctct gcacctggat ggagttttct
     2941 tttgtttatg gggttttttt ttttttggcc tgaacatttg ctgctaatgg aacttacaca
     3001 gccgagtgct ggctctgtgg aagcccgtgt ttctttgtta atttaaatga aaaaggggga
     3061 gatcccactt cagtttttgg atcccagacc tcagcttgaa cagtattcca gtgagggtaa
     3121 aaaaactggg tggggttccg ctgcagactt ccccttaccc catgcggtat tgtacacacc
     3181 cctccctccc cccccccctt cctccaaggc ttgagttggc tgctggctgg caaactcctt
     3241 cttacccata taagttattt aatgtaataa tgaagctcaa cactgtggta ggaaaatagc
     3301 cactgggggg gaaaggcaga gtttgtcact gttggatcgc ccatcctgtg ggaagggacc
     3361 gtgttttctt tacccttctg agctgtttac agctgaccac tgtgtcctgt agatgtattt
     3421 ttcagtaggt tttgtttttg ttgttgtcct taacttgctt ttccatgatg ccacccccat
     3481 ccccgtcagt gtaaatgcta tgactttaag ggtcttgggg gggaaacacc catgacctaa
     3541 ccccagttgc tgtttttcac taacttattt ctcattatcc tctggagtca gttggtggct
     3601 aaacacatag acaaggaata catttaagga aagtcccctc ctccccccgt agcagtgacc
     3661 aaatgaaaac cagcttgctg gtgactgatc agtcttaaca tctaaattag gtccgtagtt
     3721 gctctgaaat tagccatctt gatactcttg gagaaacttt acagtagtga tccccgctaa
     3781 tgaaaacgca caatgccaag ctcctgccgt gtttgttaac ccttctgacg ccatcctgag
     3841 gaccagcatg tcttaactgt gcatcatctc aacaggcctg acctgtctcc gagttgtccc
     3901 ttcacaatgt caatacattt tacactctgc a
//
