LOCUS       NM_001414936            3635 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus RAS protein activator like 3 (Rasal3), transcript
            variant 1, mRNA.
ACCESSION   NM_001414936 XM_006241059
VERSION     NM_001414936.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3635)
  AUTHORS   Saito,S., Kawamura,T., Higuchi,M., Kobayashi,T.,
            Yoshita-Takahashi,M., Yamazaki,M., Abe,M., Sakimura,K., Kanda,Y.,
            Kawamura,H., Jiang,S., Naito,M., Yoshizaki,T., Takahashi,M. and
            Fujii,M.
  TITLE     RASAL3, a novel hematopoietic RasGAP protein, regulates the number
            and functions of NKT cells
  JOURNAL   Eur J Immunol 45 (5), 1512-1523 (2015)
   PUBMED   25652366
REFERENCE   2  (bases 1 to 3635)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   3  (bases 1 to 3635)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Dec 15, 2022 this sequence version replaced XM_006241059.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.28658.1,
                                           SRR26643284.9761.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-501               JAXUCZ010000007.1  12061383-12061883   c
            502-641             JAXUCZ010000007.1  12057942-12058081   c
            642-720             JAXUCZ010000007.1  12057737-12057815   c
            721-782             JAXUCZ010000007.1  12057581-12057642   c
            783-853             JAXUCZ010000007.1  12054461-12054531   c
            854-980             JAXUCZ010000007.1  12053947-12054073   c
            981-1079            JAXUCZ010000007.1  12053766-12053864   c
            1080-1616           JAXUCZ010000007.1  12052826-12053362   c
            1617-1761           JAXUCZ010000007.1  12052238-12052382   c
            1762-1906           JAXUCZ010000007.1  12051463-12051607   c
            1907-2143           JAXUCZ010000007.1  12050446-12050682   c
            2144-2345           JAXUCZ010000007.1  12050148-12050349   c
            2346-2464           JAXUCZ010000007.1  12049938-12050056   c
            2465-2855           JAXUCZ010000007.1  12048793-12049183   c
            2856-3013           JAXUCZ010000007.1  12048438-12048595   c
            3014-3077           JAXUCZ010000007.1  12047748-12047811   c
            3078-3635           JAXUCZ010000007.1  12047090-12047647   c
FEATURES             Location/Qualifiers
     source          1..3635
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..3635
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /note="RAS protein activator like 3"
                     /db_xref="GeneID:314596"
                     /db_xref="RGD:1309019"
     exon            1..501
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..3233
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="RAS protein activator like-3 isoform 1"
                     /protein_id="NP_001401865.1"
                     /db_xref="GeneID:314596"
                     /db_xref="RGD:1309019"
                     /translation="MKTECGQTTRRSVTFWSCSRDSAMDPPLQNEDSQTQPSPLTSYR
                     WHTGGRGEKIAGGFRWGRFAGWGRALSHQEPMVSSQPAPRSLFRRVLSAPPKESRPNR
                     LRFSKSLWGRHKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDG
                     FALLEGRLVMLGEEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQV
                     HNVRKLLKRLKEKKRAKSELGAHTPRDGPSSALGSRESLATLSELDLGVERDVRVWPL
                     HPSLLGEPYCFQVTWAGGSRCFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVW
                     VHEAKGLPRAAAPGVRAELWLDGALLARTAPRAGPDQLFWAERFHFEALPPARRLSLR
                     LRGAGPAGATVGRVVLELDEVSIPRAPAAGLERWFPVLGAPAGAVLRARIRVRCLRVL
                     PSERYKELAEFLTFHYARLCMALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGT
                     AELERCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGQVVRSLCASTEDCEVDP
                     SKCPTPELPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEALGP
                     RLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEA
                     YMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPSGYQGSGDLALQLAVLHVQLCTIFAE
                     LDQKTRDSLEPLPTILQAIEEGRPVPVSVPMRLPLNTAHVQSSFSSGEKPGFLAPRDL
                     PKHTPLISKSQSLRSFQGAGSWARRRPDGERPQRRPRPVLRTQSVPARRPTHHRPAAG
                     SKPRPKGSLRTGPATSGRAWARTSTSLPRKPSVPWQRQLDQPGDRYQTPGTHRPVGKL
                     AEIQCEVAALREEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDS
                     KGGLPSNGSLGLKSLEHRMTEMECSQNQLRDTLQSLQLLSKTPGSRSQPPPLKAPCVN
                     GADLSMGT"
     exon            502..641
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            642..720
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            721..782
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            783..853
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            854..980
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1079
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            1080..1616
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1761
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            1762..1906
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            1907..2143
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2144..2345
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2346..2464
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2465..2855
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            2856..3013
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            3014..3077
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
     exon            3078..3635
                     /gene="Rasal3"
                     /gene_synonym="RGD1309019"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagacggct gctggttctg gactggccag gaaatcaagg taagagaggg tgtacgtgtg
       61 gcaccctcaa gtgtgttctg tcctttggag gcaaagctga gaagagactg gggaagatga
      121 agacagaatg tgggcagaca acgcgcagaa gtgtcacctt ttggtcttgt agcagagact
      181 ccgccatgga cccaccgctg cagaatgaag attcccaaac gcagccctcg ccgctgacgt
      241 cctatcgttg gcacactgga ggcagagggg agaagattgc tggagggttc cgctggggcc
      301 gcttcgcagg ctggggaagg gccctgagcc atcaggagcc catggtgagc agccagccag
      361 cccctagatc tctgtttcgt cgggtcctct ctgcacctcc taaggagtca cgacccaatc
      421 gcctccggtt ttccaagagc ctgtggggga ggcacaagaa cgtggtaccg ctggaaccca
      481 agctaaatcc gaaggcccca gagccagagc tggagttgga gggagcccca gacctgcgcg
      541 ctgcacatat ccctgagcct cccgcccctg acatgcctgt ttggaacatt gatggctttg
      601 ccctgctcga aggaagactg gtgatgctcg gtgaggagga gggtcctcgc caaatccgaa
      661 tgggaagtgc cagctcggaa agcagcatgc aggcagcctt ggggaacctc aaagacccag
      721 ttcggactcc tgggaaaatt gagccggaag ctactggttc caaccaggtc cacaatgttc
      781 ggaagttact caagaggctg aaggagaaga aaagggccaa gtcggaactg ggagcccaca
      841 ctcctcgaga tggaccctcc agtgctcttg gttccagaga atcgctggcc acactctctg
      901 agctggacct aggcgttgag agggatgtga gagtctggcc gctgcatcct agcctcctgg
      961 gggagccata ttgcttccag gtaacgtggg caggtgggag ccgctgtttc tcttgtcgct
     1021 cgagcgctga gagagaccgt tggattgagg accttcgtcg gcagttccag cctagccagg
     1081 acaatgtgga acgacaagag acctggctga cagtgtgggt gcacgaagcc aaagggcttc
     1141 cccgagcagc tgcacccgga gtgcgtgcgg agctgtggtt ggacggcgcg ctactggcgc
     1201 gcactgcccc tcgggcgggc cctgaccaac tcttctgggc cgaacgcttc cacttcgagg
     1261 cgttgccacc tgcccgtcgc ctgtcgctgc ggctgcgcgg agcaggcccg gcaggggcaa
     1321 ccgtgggcag ggtggtacta gaactggacg aggtgagcat cccccgcgcg cctgccgcag
     1381 gcctggagcg ctggttcccc gtgctcgggg ctccggcggg tgcggtgcta cgggcgcgga
     1441 tcagggtacg atgtctgcgc gtgctgccgt cggagcgcta taaggagtta gcggagttcc
     1501 tcaccttcca ctacgcgcgc ctgtgcatgg cgctggagcc cgcgctgtct gctcaggcca
     1561 aggaggagct ggcagcagcc atggtgcgcg tgctacgagc cactggccga gcgcaggcat
     1621 tggtgacaga cctaggaacc gcagagctgg agcgctgtgg aggccgtgaa gcgctgctat
     1681 tccgagaaaa taccttagcc acaaaggcca ttgatgaata catgaaactg gtggcacagg
     1741 agtacctcca ggagaccctg ggccaggttg tgcggagtct ctgtgcctcc accgaggact
     1801 gtgaagtgga ccccagcaag tgcccaacac cggagctgcc aaaatgccaa gctagactgc
     1861 gaagcagttg tgaggaggtt tttgaaaaca tcatccactc ttacaactat ttcccagcag
     1921 agctgggcac cgtgttctca aattggcggg aagcatgcaa agcacgaggc tctgaggcac
     1981 tgggcccccg gctggtgtgt gcttctctct tcctaaggct cctatgcccc gccatcttgg
     2041 cacctagcct ctttggcctg gcaccagagc accccgcccc aggcccagcc agaactctta
     2101 cactcatcgc caaggtcatc cagaatcttg ccaactgtgc tccgtttggt gagaaggaag
     2161 cctacatggt ctttatgaat agcttcctgg aagatcatgg accggccatg cgacacttcc
     2221 tggatcaggt agctatggtg gacacagata ccacacccag tggctaccag ggaagtggag
     2281 acctggccct ccagttggca gttcttcatg tccagctctg cacaatcttt gctgaacttg
     2341 accagaaaac tcgagacagc ttggaaccac tacccaccat ccttcaagcc attgaggagg
     2401 gtcggcctgt cccagtgtct gtaccaatgc gtcttcccct gaacactgct catgtccaat
     2461 ccagcttctc ttcaggggag aaacccggct tcctggcacc ccgagacctc cccaagcaca
     2521 ctcctctcat ttccaagagc cagtctttgc gcagctttca aggggcagga agctgggccc
     2581 gtcggcggcc agatggggag cggccccagc ggcggccgcg gccagtgctg cgcacacaga
     2641 gcgtccctgc cagacgccct acccaccatc gccctgctgc gggttccaag cctcgaccca
     2701 aaggctctct acgcactggt cctgcgactt ccggacgggc ctgggctagg acttccacct
     2761 ctctacctcg gaagccatcg gtgccttggc agcgccaact ggaccagccc ggggaccgat
     2821 accaaactcc gggaacgcac cgaccagtgg gcaagctagc agagatacaa tgcgaggtag
     2881 ctgcactccg cgaggaacag aaagccctgt cccatctggt ggagtcgctg agtacccaca
     2941 tccaggcctt gacggagcag caagagcagc tccgctgtca gctgcaggat ctggactcca
     3001 gactgggagc tgggatctca aagttggatt ctaagggtgg tctcccaagc aacggtagcc
     3061 tcgggctgaa aagtctggag caccgcatga ctgagatgga atgttctcag aaccagctga
     3121 gggataccct ccaaagccta cagcttcttt caaaaactcc aggatctcgg agccagcccc
     3181 cgcctctcaa agcaccatgt gtcaatggag ctgatctgtc gatgggcacc tgagtatttc
     3241 accccactcc atacagtctg gaagccagga gagccactac agaggatttt ctgactacct
     3301 cagtccttca tggcccttag taggggacag agtgggaggt gtcaatcact ctggtaactg
     3361 tgaggttgcc cagtaaatct ccatttcaga aaatcactgg tttctctgcc cctacaaaga
     3421 ttaatgcaag agcataccca gttctctact cagctccccc aaattcttac ctaatttgaa
     3481 gtctcccgaa gatgaaaatg attagcaaaa ttgtcctcac tattggtgtg atctaaggtc
     3541 atcactctaa aagactccat tctctcttct gtatctaaaa attctctgca tagttaaagg
     3601 tattcaataa aaggtattta tcattgttgt gggaa
//
